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At least 883 records · Page 49Linked to original sources
PubMed1991

[Brief lavage in preparation for colposcopy].

In order to reduce the amount of fluid, necessary for whole-gut irrigation, 140 consecutive patients were pretreated with Bisacodyl before they got 2 liters of mannitol solution 5%. The cleansing effect was comparable to standard whole-gut irrigation (5-6 liters of mannite 5%), patients suffered less, duration of irrigation was reduced and there were no side effects related to Bisacodyl.

Bisacodyl↗
PubMed1991

Management of cervical intraepithelial neoplasia where colposcopy is not available.

A study was carried out to determine the effectiveness of the various methods used for treating patients with cervical intraepithelial neoplasia (CIN) detected by the cervicovaginal smear screening programme at the University College Hospital, Ibadan, Nigeria, over a period of five years. During the period, 3 004 patients were screened, of whom 292 (9.7 pc) had smears suggestive of CIN. There were no facilities for colposcopic evaluation of the patients. The patients were treated by cryotherapy, electrocautery, conization of the cervix and hysterectomy. Persistence rates of CIN after cryotherapy and electrocautery were 30.3pc and 31.2pc respectively. There was no evidence of persistent CIN in patients treated with conization or hysterectomy. It is suggested that in the absence of colposcopic guidance, conization or hysterectomy should be used to treat CIN rather than blind application of locally destructive methods like cryotherapy and electrocautery, particularly the higher grades of CIN.

Adult↗
PubMed1990

Human papillomavirus detection in cervical lesions nondiagnostic for cervical intraepithelial neoplasia: correlation with Papanicolaou smear, colposcopy, and occurrence of cervical intraepithelial neoplasia.

Human papillomavirus (HPV) is associated with cervical intraepithelial neoplasia (CIN) and carcinomas. The present study involved women who had an abnormal Papanicolaou smear and whose cervix contained acetowhite area(s) that lacked the histologic features of CIN. Sequences homologous to HPV DNA, determined by Southern blot hybridization analysis, were detected in 20 of 59 cervical biopsy specimens (34%) that lacked the histologic features of CIN. When compared with the group in which HPV DNA was not detected, the HPV DNA-positive group had a lower chance of having a normal Papanicolaou smear (30 versus 61%) at the time of the biopsy. There was no difference in the colposcopic findings between the HPV DNA-positive and -negative cases for the biopsy specimens that lacked the features of CIN. However, there was a difference in the rate of histologically proved CIN in the two groups. Twelve of 17 women (71%) in the HPV DNA-positive group for whom there was follow-up information had a biopsy-proved CIN lesion noted at another location in the cervix at the time of biopsy (six) or 3-12 months after the biopsy (six). This rate was significantly higher (P less than .05) than the rate (five of 25, 20%) in the HPV DNA-negative cases, most of whom had no colposcopic abnormalities and a normal Papanicolaou smear at the follow-up examination. These findings indicate that HPV DNA detection in women with cervical lesions that lack the histologic features of CIN predicts current or future CIN in such patients.

Biopsy↗
PubMed1990

Cervical conization findings in women with dysplastic cervical cytology and normal colposcopy.

A review of 134 cervical conizations performed in a 36-month period showed that 18 were performed on patients with two or more cervical smears showing dysplasia but with essentially negative, satisfactory colposcopic evaluations, including normal colposcopically directed biopsies and endocervical curettings. A histologic diagnosis of cervical intraepithelial neoplasia (CIN) of various grades was established in 15 (83%) of the 18 conization specimens. Six (33%) of the 18 specimens harbored CIN 3. The histologic diagnosis of a more severe lesion than that indicated on cytology was rendered in five of the cases. Cervical conization should be performed when colposcopic evaluation of the cervix, vagina and vulva fails to identify the source of persistent CIN on Papanicolaou smears.

Adult↗
PubMed1990

[Proposal for a data collection system for colposcopy services].

A computerized system for colpocytologic data collection and filing, is presented. A descriptive and easy to elaborate recording of anamnestical data and examination findings is achieved using two correlated files. Step by step filing is obtained by multichoice scheme which progressively appears on the screen.

Colposcopy↗
PubMed1989

Colposcopy of condylomatous men.

The male partners of women diagnosed with human papilloma virus (HPV) or dysplasia were examined colposcopically. Anogenital infection was found in 82% of the men, and dysplasia in two of the partners of dysplastic women. Men may not be merely asymptomatic carriers of HPV.

Adult↗
PubMedDate not supplied

Should smears in a colposcopy clinic be taken after the application of acetic acid?

Conventionally, cervical smears obtained during a colposcopic examination are taken before the application of acetic acid. However, this occasionally precipitates bleeding and removes epithelium from the cervix, particularly in the presence of cervical pathology, making colposcopic evaluation difficult. This study examined the possibility of deferring the smear until the end of the colposcopic examination. In the first part of the study, the cytologic results on cervical samples taken from the same patient before and after the application of acetic acid were compared. In the second part of the study, only one smear was taken per patient (either before or after colposcopic assessment) to eliminate the possibility that the taking of the first smear affected the quality of the second. The results of both parts of the study showed that deferring the smear until after the application of acetic acid leads to an unacceptably high rate of unsatisfactory and falsely negative smears. Thus, deferring the taking of the cervical smear until after the colposcopic evaluation results in a poor cytologic evaluation, although it might facilitate the colposcopic examination in some patients.

Acetates↗
PubMed1987

Human papillomavirus-associated lesions of the penis: colposcopy, cytology, and histology.

The diagnosis and therapy of human papillomavirus infections in men is of potential benefit because it may decrease the reservoir of virus from which genital condylomata or squamous neoplasia may arise in women. To investigate the efficacy of diagnostic methods, we examined the 127 male sexual partners of 127 women with cervical intraepithelial neoplasia. Eighty-three mostly asymptomatic men (65%) had from one to 50 (median three) small (median 3 mm) human papillomavirus-associated lesions consisting of condylomata (80 cases) and penile dysplasia (three cases). The colposcope aided diagnosis or was necessary for diagnosis of 59% of the lesions. Routine application of 3% or 5% acetic acid yielded white or grayish epithelial changes in 22% of the cases, which would have been missed without this technique. Papular, flat, spiked, and mixed lesions were more common (85%) than papillary changes or classic condylomata acuminata (15%). In contrast to smears from the external penile surface, smears obtained from the male urethra were satisfactory in most cases and yielded positive results in nine men (7%). Condylomata are common in male partners of women with cervical intraepithelial neoplasia, but the lesions are frequently not apparent unless magnification and acetic acid are used. Cytologic smears may aid in the diagnosis of condylomata in the urethra.

Adult↗