SEARCH · Search PubMed

Results for “CALIFORNIA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 883 records · Page 49Linked to original sources

PubMed2006

Characterization of benthic communities and physical habitat in the Stanislaus, Tuolumne, and Merced Rivers, California.

The primary goal of this study was to characterize physical habitat and benthic communities (macroinvertebrates) in the Stanislaus, Tuolumne and Merced Rivers in California's San Joaquin Valley in 2003. These rivers have been listed as impaired water bodies (303 (d) list) by the State of California due to the presence of organophosphate (OP) insecticides chlorpyrifos and diazinon, Group A pesticides (i.e., organochlorine pesticides), mercury, or unknown toxicity. Based on 10 instream and riparian physical habitat metrics, total physical habitat scores in the Stanislaus River ranged from 124 to 188 (maximum possible total score is 200). The highest total habitat score was reported at the upstream site. Tuolumne River physical habitat scores ranged from 86 to 167. Various Tuolumne River physical habitat metrics, including total habitat score, increased from downstream to upstream in this river. Merced River physical habitat scores ranged from 121 to 170 with a significant increase in various physical habitat metrics, including total habitat score, reported from downstream to upstream. Channel flow (an instream metric) and bank stability (a riparian metric) were the most important physical habitat metrics influencing the various benthic metrics for all three rivers. Abundance measures of benthic macroinvertebrates (5,100 to 5,400 individuals) were similar among the three rivers in the San Joaquin watershed. Benthic communities in all three rivers were generally dominated by: (1) Baetidae species (mayflies) which are a component of EPT taxa generally considered sensitive to environmental degradation; (2) Chironomidae (midges) which can be either tolerant or sensitive to environmental stressors depending on the species; (3) Ephemerellidae (mayflies) which are considered sensitive to pollution stress; and (4) Naididae (aquatic worms) which are generally considered tolerant to environmental stressors. The presence of 117 taxa in the Stanislaus River, 114 taxa in the Tuolumne River and 96 taxa in the Merced River implies that the benthic communities in these streams are fairly diverse but without a clear definition of benthic community expectations it is unknown if these water bodies are actually impaired.

Animals↗

PubMed2005

California ground squirrel (Spermophilus beecheyi) defenses against rattlesnake venom digestive and hemostatic toxins.

Previous studies have shown that some mammals are able to neutralize venom from snake predators. California ground squirrels (Spermophilus beecheyi) show variation among populations in their ability to bind venom and minimize damage from northern Pacific rattlesnakes (Crotalus oreganus), but the venom toxins targeted by resistance have not been investigated. Four California ground squirrel populations, selected for differences in local density or type of rattlesnake predators, were assayed for their ability to neutralize digestive and hemostatic effects of venom from three rattlesnake species. In Douglas ground squirrels (S. b. douglasii), we found that animals from a location where snakes are common showed greater inhibition of venom metalloprotease and hemolytic activity than animals from a location where snakes are rare. Effects on general proteolysis were not different. Douglas ground squirrels also reduced the metalloprotease activity of venom from sympatric northern Pacific rattlesnakes (Crotalus oreganus oreganus) more than the activity of venom from allopatric western diamondback rattlesnakes (C. atrox), but enhanced fibrinolysis of sympatric venom almost 1.8 times above baseline levels. Two Beechey ground squirrel (S. b. beecheyi) populations had similar inhibition of venoms from northern and southern Pacific rattlesnakes (C. o. helleri), despite differences between the populations in the locally prevalent predator. However, the venom toxins inhibited by Beechey squirrels did vary among venom from Pacific rattlesnake subspecies, and between these venoms and venom from allopatric western diamondback rattlesnakes. Blood plasma from Beechey squirrels showed highest inhibition of metalloprotease activity of northern Pacific rattlesnake venom, general proteolytic activity and hemolysis of southern Pacific rattlesnake venom, and hemolysis by allopatric western diamondback venom. These results reveal previously cryptic variation in venom activity against resistant prey that suggests reciprocal adaptation at the molecular level.

Adaptation, Physiological↗

PubMed2006

Public health insurance enrollment among immigrants and nonimmigrants: findings from the 2001 California Health Interview Survey.

We examine whether adult immigrants in California had the same likelihood of having public health insurance as nonimmigrants with comparable characteristics, using 44,434 non-elderly adult samples of the 2001 California Health Interview Survey public use data. Multinomial logistic regression was used to assess the likelihood of public health insurance relative to private (employment-based or privately purchased) health insurance by generation status, controlling for individual characteristics. The outcome of interest was public health insurance among three health insurance categories: private health insurance, public health insurance, and uninsured. Both first and second generation immigrants were more likely to have public health insurance than were nonimmigrants. However, the difference vanished, when demography, socioeconomic status, health status, employment sector, and English facility were controlled for. The combined effect of lower returns to education and lower employment-based insurance offer rates seems to be the underlying cause of higher prevalence of public health insurance among ethnic minorities.

Adolescent↗

PubMed2007

Factors in the delayed HIV presentation of immigrants in Northern California: implications for voluntary counseling and testing programs.

To describe the determinants of delayed HIV presentation in one Northern California County, the authors identify persons with an opportunistic infection (OI) at HIV diagnosis. From 2000-2002, a sample of HIV patients attending a public AIDS program (n=391) were identified. Immigrants composed 24% of our sample; 78.7% of immigrants were Hispanic. Immigrants, compared to U.S.-born patients, presented with lower initial CD4+ counts at diagnosis than U.S.-born patients (287 cells/mm(3) vs. 333 cells/mm(3), p=0.143), were more likely to have an OI at HIV diagnosis (29.8% vs. 17.2%, p=0.009), and were more likely to be hospitalized at HIV diagnosis (20.2% vs. 12.5%, p=0.064). We found only immigrant status was significantly and independently associated with delayed presentation. Interviews with 20 newly HIV diagnosed Hispanic patients suggest lack of knowledge regarding HIV risk, social stigma, secrecy and symptom driven health seeking behavior all contribute to delayed clinical presentation. The main precipitants of HIV testing for immigrants were HIV/AIDS related symptoms and sexually transmitted infection (STI)/HIV diagnosis in a sexual partner. These results support augmentation of STI/HIV voluntary clinical testing and partner notification services along the Mexico-California migrant corridor.

AIDS-Related Opportunistic Infections↗

PubMed2006

Koreans' use of medical services in Seoul, Korea and California.

This study assessed the types of health care services used by Korean immigrants, and differences in use between different countries, genders, health insurance status, acculturation status, and cardiovascular risk. Participant selection used probability sampling to represent the adult populations of California, United States, and Seoul, Republic of Korea. A telephone survey was administered to 2,830 adult Korean-Californians and 500 adult Koreans living in Seoul. Female gender was significantly associated with higher use of outpatient services, ER usage, and hospitalization. Californian residence was significantly associated with higher outpatient usage and lower hospitalization rates. Health insurance was associated with higher allopathic health care utilization, and lower traditional health care usage, and acculturation with lower traditional health care usage. Higher self-reported cardiac risk factors were associated with lower allopathic and higher traditional health care. This suggests barriers to allopathic health care, but not traditional health care, for Koreans living in California without health insurance.

Acculturation↗

PubMed2005

TPMG Northern California appointments and advice call center.

Kaiser Permanente (KP) has been developing its use of call centers as a way to provide an expansive set of healthcare services to KP members efficiently and cost effectively. Since 1995, when The Permanente Medical Group (TPMG) began to consolidate primary care phone services into three physical call centers, the TPMG Appointments and Advice Call Center (AACC) has become the "front office" for primary care services across approximately 89% of Northern California. The AACC provides primary care phone service for approximately 3 million Kaiser Foundation Health Plan members in Northern California and responds to approximately 1 million calls per month across the three AACC sites. A database records each caller's identity as well as the day, time, and duration of each call; reason for calling; services provided to callers as a result of calls; and clinical outcomes of calls. We here summarize this information for the period 2000 through 2003.

Adolescent↗

PubMed2006

Evaluating a program to build data capacity for core public health functions in local maternal child and adolescent health programs in california.

OBJECTIVES: To improve local Maternal and Child Health programs' capacity to collect and analyze data to support core public health functions, the California Maternal and Child Health Branch (CAMCHB) and the University of California San Francisco Family Health Outcomes project (FHOP) entered into a cooperative agreement. FHOP utilizes a 6-pronged strategy: face-to-face training, telephone technical assistance, on-site consultation, development of automated analytic tools, development of written guidelines, and web dissemination of data and materials. We evaluated the acceptability and effectiveness of these approaches. METHODS: Local Health Jurisdiction (LHJ) staff completed a self-administered questionnaire on use of and satisfaction with FHOP's services. A 34-item assessment tool was used to independently evaluate each 5-year community assessment plan submitted by LHJs to the CAMCHB. Administrative data on the use of FHOP's service was also considered. Correlational analyses were done to determine if use of FHOP services and materials was related to more adequate plans. RESULTS: LHJs with higher overall adequacy scores on their plans had an overall higher level of use of FHOP's products and services. LHJs with higher adequacy scores reported calling FHOP for technical assistance more frequently, using FHOP's book - "Developing an Effective Planning Process: A Guide for Local MCH Programs," and using FHOP's automated tools including EpiBC, an EpiINFO based program for birth certificate analysis, and Microsoft Excel data analysis templates. CONCLUSION: This 6-pronged strategy is well utilized and accepted by local MCH staff and appears to have some degree of association with better quality of local MCH plan documents.

Adolescent↗

PubMed1993

The effectiveness of seat belt legislation in reducing various driver-involved injury rates in California.

This study makes use of econometric models to examine the impact of seat belt laws on various driver-involved injury rates in California in both single- and multiple-vehicle accidents. The study makes use of a large data set from the U.S. D.O.T. State Traffic Accident Files and accounts for the general impact of seat belt laws as well as their dynamic effects on injury rates. The models adjust for a wide range of additional contributing factors to injury rates, including the influence of unemployment rates, speed limits, companion effects, and others. Robust results are obtained for the efficacy of seat belt legislation on reducing (moderate to fatal) injury rates in California.

Accidents, Traffic↗

PubMed1996

Evaluation of California's commercial driver license program.

This study evaluated the traffic-safety impact of the California Department of Motor Vehicles' Commercial Driver License (CDL) program. The program, initiated on 1 January 1989, began a new commercial-license classification and endorsement system, implemented stronger licensing standards and more comprehensive tests of knowledge and driving competency, required drivers to report specific violations to employers, and provided for more stringent post-licensing sanctions on negligent operators. The effect of the program on fatal and fatal/injury accidents involving heavy vehicles operated by drivers licensed in California was assessed using intervention time-series analysis. The results indicate that the CDL program did not have a statistically significant effect on either accident measure.

Accidents, Traffic↗

PubMed1979

Cesarean section in California--1960 through 1975.

The cesarean section rate has been rising in California since 1965. In this article, we describe the trend in cesarean section rates in California from 1960 to 1975 in relation to maternal and infant variables. Approximately proportionate increases in cesarean section rates by infant birth weight and maternal race were found. Cesarean section rates for women under 20 years of age and for those of first parity have risen proportionately more than rates for other age and parity groups. We also found that cesarean section rates for births at gestational age's exceeding 42 weeks have risen proportionately more than rates for births at other gestational ages. Maternal mortality ratios associated with cesarean section were twice those associated with noncesarean births for the years 1973, 1974, and 1975. Possible explanations of the current cesarean section rate include an increase in indications for the procedure, use of the fetal monitor, and the current medical-legal climate. The potential problems that cesarean section may create for the mother and infant are higher rates of iatrogenic prematurity and respiratory distress and of maternal morbidity and mortality.

Adult↗

PubMed1989

A prenatal diagnostic center's first-year experience with the California alpha-Fetoprotein Screening Program.

The University of California Davis Medical Center has offered secondary and tertiary care to pregnant patients with abnormal maternal serum alpha-fetoprotein levels since the start of the California alpha-Fetoprotein Screening Program in April 1986. In our first year of involvement with this method of prenatal screening, 452 patients were referred to our center for further evaluation and follow-up of either high or low maternal serum alpha-fetoprotein levels, as determined by the standard multiple of the median adjusted for maternal weight, race, and presence of insulin-dependent diabetes mellitus. This article presents the first-year results of our clinical experience. Information is presented concerning medical complications, screening and diagnostic test results and their confirmation, clinical procedures performed, and postpartum follow-up reports. Findings of pregnancy outcomes associated with low and high alpha-fetoprotein levels are presented and discussed.

Adult↗

PubMed1989

Chromium carcinogenicity: California strategies.

Hexavalent chromium was identified by California as a toxic air contaminant (TAC) in January 1986. The California Department of Health Services (CDHS) concurred with the findings of the International Agency for Research on Cancer that there is sufficient evidence to demonstrate the carcinogenicity of chromium in both animals and humans. CDHS did not find any compelling evidence demonstrating the existence of a threshold with respect to chromium carcinogenesis. Experimental data was judged inadequate to assess potential human reproductive risks from ambient exposures. Other health effects were not expected to occur at ambient levels. The theoretically increased lifetime carcinogenic risk from a continuous lifetime exposure to hexavalent chromium fell within the range 12-146 cancer cases per nanogram hexavalent chromium per cubic meter of air per million people exposed, depending on the potency estimate used. The primary sources found to contribute significantly to the risk of exposure were chrome platers, chromic acid anodizing facilities and cooling towers utilizing hexavalent chromium as a corrosion inhibitor. Evaluation of genotoxicity data, animal studies and epidemiological studies indicates that further consideration should be given to the potential carcinogenicity of hexavalent chromium via the oral route.

Air Pollutants↗

PubMed1992

Copper tolerance and copper accumulation of herbaceous plants colonizing inactive California copper mines.

Herbaceous plant species colonizing four copper mine waste sites in northern California were investigated for copper tolerance and copper accumulation. Copper tolerance was found in plant species colonizing soils with high concentrations of soil copper. Seven of the eight plant species tested were found at more than one copper mine. The mines are geographically isolated, which makes dispersal of seeds from one mine to another unlikely. Tolerance has probably evolved independently at each site. The nontolerant field control population of Vulpia microstachya displays significantly higher tolerance to copper at all copper concentration levels tested than the nontolerant Vulpia myrous population, and the degree of copper tolerance attained by V. microstachya at the two copper mines was much greater than that found in V. myrous. It suggests that even in these two closely related species, the innate tolerance in their nontolerant populations may reflect their potential for evolution of copper tolerance and their ability to initially colonize copper mine waste sites. The shoot tissue of the copper mine plants of Arenaria douglasii, Bromous mollis, and V. microstachya accumulated less copper than those plants of the same species from the field control sites when the two were grown in identical conditions in nutrient solution containing copper. The root tissue of these mine plants contain more copper than the roots of the nonmine plants. This result suggests that exclusion of copper from the shoots, in part by immobilization in the roots, may be a feature of copper tolerance. No difference in the tissue copper concentration was detected between tolerant and nontolerant plants of Lotus purshianus, Lupinus bicolor, and Trifolium pratense even though the root tissue had more copper than the leaves. It suggests that copper tolerance in these legume species is not due to a mechanism of differential capacity for copper accumulation in the roots. Different mechanisms of copper tolerance may have evolved among the plant species colonizing the northern California copper mine waste sites.

California↗

PubMed1988

California mandatory seat belt law: the effect of recent legislation on motor vehicle accident related maxillofacial injuries.

This study evaluated the effects of the California mandatory seat belt law on prevention of motor vehicle accident (MVA)-related maxillofacial injuries. The records of 950 MVA-related injury victims treated at San Francisco General Hospital during comparable 3-month periods in 1985 (451) and 1986 (499) were reviewed to assess the effect of seat belt legislation on reduction of maxillofacial trauma. No significant difference was found in the injury severity scores between the two study periods. In addition, this study did not confirm the reported beneficial effect of seat belt legislation on reduction of MVA-related facial injuries in California. This finding was attributed to poor compliance with the law (50.3% compliance rate).

Accidents, Traffic↗

PubMed2005

Bicycle safety helmet legislation and bicycle-related non-fatal injuries in California.

The objective of this study was to determine whether the bicycle safety helmet legislation in California, enacted in 1994, was associated with statistically significant reductions in head injuries among bicyclists aged 17 years and under who were subjected to the law. The study used 44,069 patient discharge cases from all public hospitals in California, from 1991 through 2000, and a case-control design to make direct comparisons between those subjected to the law (Youth) and those who were not (Adult) across the pre- and post-legislation periods. An aggregate data analysis approach and a pooled disaggregate data fitting technique using multinomial logit models were applied. The legislation was found to be associated with a reduction of 18.2% (99% confidence interval: 11.5-24.3%) in the proportion of traumatic brain injuries (Head-TBI) among Youth bicyclists. The proportions of other head, face, and neck injuries were not significantly changed across the pre- and post-legislation periods in this age group but there was a corresponding increase of 9% (5-13%) in the proportion of all other injuries. On the other hand, there was no statistically significant change in the proportions of injury outcomes for Adult bicyclists. The youngest riders, aged 0-9 years, had the greatest decrease in the proportion of Head-TBI. The reduction was the same for motor vehicle and non-motor-vehicle-related incidents. The bicycle safety helmet legislation was associated with a decrease in the likelihood of Head-TBI for non-urban residents but not for urbanites, for males but not for females, and for Whites, Asians, and Hispanics, but not Blacks and others.

Bicycling↗

PubMed2004

Cervical cancer among Hmong women in California, 1988 to 2000.

BACKGROUND: The Hmong immigrated to the United States from Laos after the Vietnam conflict ended. Hmong encounter numerous readjustment issues, including health care. Traditional Hmong health beliefs and practices encompass more spiritual than biological etiologies. Hmong usually seek the first course of treatment from traditional healers, as they had in Laos. This practice delays early diagnosis and treatment of disease because biomedicine is used only as a last resort. This study examined cervical cancer incidence, mortality, and other tumor characteristics in the Hmong female population of California between 1988 and 2000. METHODS: Data from the California Cancer Registry were used to calculate annual average incidence, mortality, and age-specific rates for Hmong women diagnosed with cervical cancer. The population at risk was estimated with linear interpolation using data from the 1990 and 2000 censuses. RESULTS: Hmong women experienced incidence and mortality rates three and four times higher than Asian/Pacific Islander and non-Hispanic white women, respectively. Fifty-one percent of Hmong women chose no treatment, compared to 5.8% for Asian/Pacific Islander women and 4.8% for non-Hispanic white women. Hmong women aged >/= 40 years carried an unequal burden of cervical cancer. They were more likely to be diagnosed with cervical cancer at later stages and poorer histologic grades, and had a lower survival rate than younger Hmong females. CONCLUSIONS: Cervical cancer is clearly a public health issue that threatens the health and well-being of Hmong women. Culturally sensitive screening and prevention programs need to be developed to target older Hmong women using bilingual and bicultural Hmong women health educators using verbal communication.

Adolescent↗

PubMed2004

The life cycle of crime guns: a description based on guns recovered from young people in California.

STUDY OBJECTIVE: We describe the life cycle of crime guns recovered from young people-the movement of those guns from manufacture to criminal use-and identify associations between the characteristics of those guns and their possessors, purchasers, sellers, and places of origin. METHODS: This is a cross-sectional study of data from gun ownership tracing records compiled by the Bureau of Alcohol, Tobacco, Firearms and Explosives for 2,121 crime guns recovered in California from persons younger than 25 years and traced in 1999. Purchaser and seller data for handguns were updated when possible by linking to California handgun sales records. RESULTS: The 2,121 traced guns were recovered from 1,717 young people. Guns recovered from persons aged 21 to 24 years were most frequently also purchased by persons aged 21 to 24 years; those recovered from persons younger than 18 years were most often purchased by persons aged 45 years or older. Small-caliber handguns made up 41.0% of handguns recovered from persons younger than 18 years but 25.2% of handguns recovered from persons aged 21 to 24 years. The median time from sale to recovery (commonly called time to crime) for all guns was 6.4 years (interquartile range 2.7 to 12.4 years). A time to crime of less than 3 years, suggesting deliberate gun trafficking, was observed for 17.3% of guns recovered from persons younger than 18 years but 34.6% of guns recovered from persons aged 21 to 24 years. Ten retailers who sold 10 or more traced guns accounted for 13.1% of all guns traced to a retailer. Handguns whose purchaser and possessor were the same person were more likely than others to be large-caliber semiautomatic pistols (29.3% and 11.7%, respectively); their median time to crime was 0.2 years (69 days). CONCLUSION: Analysis of crime-gun ownership traces reveals patterns that may help refine gun violence prevention efforts and render them more effective.

Adolescent↗

PubMed2006

Primary total knee arthroplasty in California 1991 to 2001: does hospital volume affect outcomes?

This study reports the relationship between hospital surgical volume and outcomes after total knee arthroplasty. Discharge data from 1991 to 2001 were obtained from California's Office of Statewide Health Planning and Development and linked to California death records. Multivariate logistic regression models were performed to examine the association between hospital volume and complications. The models were adjusted for patient age, sex, race/ethnicity, insurance type, Charlson comorbidity index, hospital type and size, year of surgery, and whether patients underwent bilateral procedures. A total of 222684 primary total knee arthroplasties were identified during the study period. Patients treated at low volume hospitals had a higher likelihood in the 90 days after discharge of death (rate 0.55% vs 0.49%, odds ratio [OR] 1.50, 95% confidence interval [CI] 1.14-1.98, P = .004), and readmission for infection (1.13% vs 0.65%, OR 1.60, 95% CI 1.21-2.12, P = .001), pulmonary embolism (0.48% vs 0.39%, OR 1.45, 95% CI 1.07-1.97, P = .016), and thrombophlebitis (0.49% vs 0.28%, OR 2.12, 95% CI 1.47-3.05, P </= .001). This study confirms the relationship of lower hospital volumes to a higher OR for complications after total knee arthroplasty.

Aged↗