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Brainport: an alternative input to the brain.

Brain Computer Interface (BCI) technology is one of the most rapidly developing areas of modern science; it has created numerous significant crossroads between Neuroscience and Computer Science. The goal of BCI technology is to provide a direct link between the human brain and a computerized environment. The objective of recent BCI approaches and applications have been designed to provide the information flow from the brain to the computerized periphery. The opposite or alternative direction of the flow of information (computer to brain interface, or CBI) remains almost undeveloped. The BrainPort is a CBI that offers a complementary technology designed to support a direct link from a computerized environment to the human brain - and to do so non-invasively. Currently, BrainPort research is pursuing two primary goals. One is the delivery of missing sensory information critical for normal human behavior through an additional artificial sensory channel around the damaged or malfunctioning natural sensory system. The other is to decrease the risk of sensory overload in human-machine interactions by providing a parallel and supplemental channel for information flow to the brain. In contrast, conventional CBI strategies (e.g., Virtual Reality), are usually designed to provide additional or substitution information through pre-existing sensory channels, and unintentionally aggravate the brain overload problem.

Brain↗

FEM simulation of the eye structure with bio-heat analysis.

Computer simulation on medical sciences has gain increasing popularity as computational technology advances. Successful thermal modeling of the human eye will assist in enabling early detections of eye abnormalities such as inflammatory. However, validity of every computer simulated results must be benchmarked with experimental measurement and this can be a daunting task especially in biomedical fields where experimental data is not in abundance. This paper presents a 2D finite element (FE) human eye model developed to simulate its thermal steady state conditions based on the properties and parameters reported in the open literatures. The results are verified with experimental and computational results obtained by previous studies on human as well as animal eyes. Results show discrepancy of only 0.33% when compared to images from infrared (IR) screening and a difference of only 0.127% compared to another finite element model. The sensitivity analysis also provides good agreement with results by previous studies. This promising simulation allows new possibility in computational methods for eye health care.

Artificial Intelligence↗

Analysis of heroin seized in France.

Because of the increase in heroin trafficking in France, it was decided that data on samples of heroin seized in the country would be filed in a computer in the Interregional Forensic Science Laboratory at Lyon. The computer file has made it possible to identify certain physical and chemical similarities among samples of seized heroin. According to the data in the computer file, the colour, purity, diluents etc. of the heroin offered on the street has changed significantly since 1987. The Laboratory will be in a better position to identify the geographical sources of heroin seized in France once samples of seized heroin have been obtained directly from their countries of origin.

Databases, Factual↗

Simulation of micropopulations in epidemiology: tutorial 1. Simulation: an introduction. A series of tutorials illustrated by coronary heart disease models.

This is the first in a series of tutorials concerning the simulation of micropopulation models for use in epidemiological research. The series emphasizes the techniques that are in use at the National Micropopulation Simulation Resource at the University of Minnesota. This initial series of tutorials uses chronic disease models, specifically coronary heart disease models, to illustrate the principles and methodologies employed. The series is intended for persons having some familiarity with electronic, digital computation and desiring to know more about a specific class of simulations, namely those that apply Monte Carlo techniques in the simulation of micropopulation models as a part of biomedical research. It is the author's hope that these tutorials will be particularly useful for students in medical informatics; they could also be of interest to professionals in both the computational and the biomedical sciences.

Chronic Disease↗

Computer animation and improved student comprehension of basic science concepts.

Many medical students have difficulty learning basic science, either because they find the material challenging to comprehend or because they believe it has limited clinical application. Computer-assisted instruction (CAI)--ie, computer animation--can clarify instruction by allowing students to visualize complex, dynamic processes in an interesting presentation. At West Virginia School of Osteopathic Medicine (WVSOM) in Lewisburg, a series of computer animations have been developed to present concepts in molecular and cellular biology. The author conducted an investigation to compare the efficacy of one representative computer animation with that of traditional textbook material. The subjects were 22 students who had been admitted to WVSOM but who had not yet begun classes. The experimental design of the study consisted of a prelesson test, a lesson, and a postlesson test. The lesson explained the process of deoxyribonucleic acid (DNA) replication using either a computer animation (n=12) or a chapter from a textbook (n=10). Lesson comprehension as measured by the tests was significantly higher for subjects who used the computer animation than for subjects who used the textbook (P<.01). Furthermore, reviewing the text after studying with the computer animation did not raise test scores, suggesting that the animation was sufficient for learning and the text was unnecessary. After the study, a majority of subjects indicated a preference for the animation over the text. These results demonstrate that CAI can be an effective tool for relating basic science to medical students by improving comprehension and eliciting interest in the lessons.

Adult↗

Recommended data elements for the descriptive cataloging of computer-based educational materials in the health sciences.

A large part of the mission of the National Library of Medicine is to collect, index, and disseminate the world's biomedical literature. Until recently, this related only to serial and monographic material, but as new forms of information appear responsibility for bibliographic control of these also must be assumed by the National Library of Medicine. This paper briefly describes the type of information that will be necessary before descriptive cataloging of computer-based educational materials can be attempted.

Cataloging↗

Implementation of a computer-based test generator to evaluate health professions continuing education.

A variety of artificial-intelligence-based expert medical systems have been adapted to evaluate a learner's performance in the information areas in which the systems are expert. This paper describes a similar adaptation of a computer-based health sciences tutor (called the COMMES system). The Evaluation Consultant system to be described adapts the COMMES system to become a test generator. This computer-based consultant generates tests entirely on its own, covering programs of study that the COMMES system previously constructed to satisfy a user's identified needs. A health professional is awarded continuing education credits after (1) finishing a study unit constructed by COMMES and (2) completing successfully a test created by the Evaluation Consultant. This system is being implemented in several test sites and has significant advantages for the support of continuing education, especially in rural or isolated areas.

Computer-Assisted Instruction↗

A survey of computer search service costs in the academic health sciences library.

The Norris Medical Library, University of Southern California, has recently completed an extensive survey of costs involved in the provision of computer search services beyond vendor charges for connect time and printing. In this survey costs for such items as terminal depreciation, repair contract, personnel time, and supplies are analyzed. Implications of this cost survey are discussed in relation to planning and price setting for computer search services.

California↗

Government regulations and other influences on the medical use of computers.

This paper presents points brought out in a panel discussion held at the 12th Hawaiian International Conference on System Sciences, January 1979. The session was attended by approximately two dozen interested parties from various segments of the academic, government, and health care communities. The broad categories covered include the specific problems of government regulations and their impact on specific clinical information systems installed at The University of Texas Health Science Center at Dallas, opportunities in a regulated environment, problems in a regulated environment, vendor-related issues in the marketing and manufacture of computer-based information systems, rational approaches to government control, and specific issues related to medical computer science.

Computers↗

Time dependent neural network models for detecting changes of state in complex processes: applications in earth sciences and astronomy.

A computational intelligence approach is used to explore the problem of detecting internal state changes in time dependent processes; described by heterogeneous, multivariate time series with imprecise data and missing values. Such processes are approximated by collections of time dependent non-linear autoregressive models represented by a special kind of neuro-fuzzy neural network. Grid and high throughput computing model mining procedures based on neuro-fuzzy networks and genetic algorithms, generate: (i) collections of models composed of sets of time lag terms from the time series, and (ii) prediction functions represented by neuro-fuzzy networks. The composition of the models and their prediction capabilities, allows the identification of changes in the internal structure of the process. These changes are associated with the alternation of steady and transient states, zones with abnormal behavior, instability, and other situations. This approach is general, and its sensitivity for detecting subtle changes of state is revealed by simulation experiments. Its potential in the study of complex processes in earth sciences and astrophysics is illustrated with applications using paleoclimate and solar data.

Artificial Intelligence↗

Environmental biotechnology informatics.

Environmental biotechnology informatics is in its infancy and is growing fast. Computer and information science can assist environmental biotechnology by developing biological databases and building mathematical models of biological systems. Funding and training limitations in this field may, however, hinder its future growth.

Biodegradation, Environmental↗