[Remnants and abnormalities of the thyreoglossal tract: histological and statistical study of 200 operative specimens of laryngectomy].
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The case of a 24-year-old woman with follicular carcinoma arising de novo in a thyroglossal duct is reported. A review of the literature disclosed seven case reports of thyroglossal duct carcinoma with a mixed papillary-follicular pattern. There are three criteria for the diagnosis of follicular carcinoma of a thyroglossal duct: presence of a thyroglossal duct, absence of carcinoma within the thyroid gland and angioinvasion. A plan of treatment, based on the literature survey, should include Sistrunk excision of the tumour if possible, and subtotal thyroidectomy should be performed to eliminate the presence of a primary thyroid carcinoma.
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This study was undertaken in order to find out the frequency of thyroglossal duct remnants and to specify the relationship between this tract the hyoïd bone. The remnants having undergone cystic pathology refer to tracks edged with an epithelial lining which can be various, associated or isolated, types. Thyroïd follicles may be annexed to this track, in or out of its cystic part. The systematic study of 23 hyoïdal and sub hyoïdal regions of adults exempt of any pathologic remnants allows one to find tracks in 13 cases, that is in every other case. This frequency is higher than the one normally described. These remnants always refer to some thyroïd follicle islands and rarely to an epithelial track. Furthermore, we can sometimes observe the frankly intra hyoïdal situation of the thyroid tissue. This last location is discussed according to embryologic data.
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