Public notification to families with newborns at risk of methemoglobinemia from drinking water exposure, Clymer, New York, 1996-1998.
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In 1998 in 33 laboratories in the Czech Republic 1,223 rotavirus infections were revealed. The largest number of positive infections was recorded in children under the age of 3 years. The most frequent diagnostic procedure is latex agglutination which was used in 29 laboratories. In six departments the positive findings are reported directly to the appropriate epidemiological department. In the information system of the hygiene service, Epidat, in 1998 239 cases were reported, i.e. 19.5% of those confirmed by laboratory tests. The authors discuss the contemporary impact of rotavirus infections in the Czech Republic.
OBJECTIVES: To describe and analyze spontaneous reports of central nervous system (CNS) demyelinating disease including multiple sclerosis, following vaccination with GenHevac B vaccine, from 1989 to December 31, 1998. METHODS: Descriptive analysis of adverse event reports in the vaccinated population, including the number of cases of CNS demyelinating disease, their frequencies, their dates of onset in relation to dates of report and their distribution according to age, sex and the number of injections. A Kaplan-Meier curve was used to analyze the time period between the last dose of vaccine and the onset of CNS demyelinating disease. RESULTS: Overall, 187 cases of CNS demyelinating disease were spontaneously reported, (0.54 reports per 100,000 doses of GenHevac B distributed). The average time period between the occurring date of onset of the disease and its subsequent report was 24 months. The average age of onset was 31.7 years old and 73% of cases were women. The time between the last dose of vaccine and the onset of disease was regularly distributed from 1 day to 5 years (median: 60 days). CONCLUSION: These results, together with available clinical, epidemiological data regarding multiple sclerosis, do not suggest a causal relationship between CNS demyelinating disease and vaccination with GenHevac B.
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The pathologist, like every other doctor, is pledged to secrecy. The pledge of secrecy also extends to what he has found in the body of the deceased be they secrets of the patient or of a third party. Third party secrets are not protected by the obligation of secrecy if safequarding them would be against the "projected interests of the patient". The present obligation to notify according to the burial laws of some states applies to pathologists even when possible medical contributary faults are established, but he faces a dilemma which cannot be solved juridically at present. Alteration of the law should take this into account.
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