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At least 865 records · Page 48Linked to original sources
PubMed1978

The development of haemoglobin A2 in normal negro infants and in sickle cell disease.

The development of haemoglobin A2 levels from birth to 3 years has been compared in normal, beta-thalassaemia trait, sickle cell (SS) disease, and S-beta-thalassaemia genotypes. Hb A2 levels were almost identical in normals and in children with SS disease at 1, 2 and 3 years. The most rapid increases in Hb A2 levels occurred before 6 months but levels were still rising at the end of the third year. Sickle cell-beta+ thalassaemia could be differentiated from SS disease by the higher Hb A2 levels between 6 months and 1 year. Insufficient data were available on S-beta o thalassaemia but since Hb A2 levels in this condition are generally higher than those in S-beta+ thalassaemia, differentiation from SS disease may may also be possible from the age of 6 months.

Age Factors↗
PubMed1977

HLA and cancer in South African Negroes.

Five hundred patients with cancer were tested for 32 HLA antigens and the antigen frequencies compared with those of 500 control subjects matched for race, sex and age. Although the overall frequencies showed no significant differences, detailed analysis with regard to site of cancer, age and the number of antigens detected at each locus revealed significant differences. Phenotype tables and haplotype frequencies have been included.

Black People↗