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At least 865 records · Page 48Linked to original sources
PubMed2006

A prospective study of anticardiolipin antibodies as a risk factor for venous thrombosis in a general population (the HUNT study).

We prospectively examined whether there is an association between elevated anticardiolipin antibody levels and the risk for a future first venous thrombosis (VT) in a general population. We studied this in a large population-based nested case-cohort study of 508 VT cases and 1464 matched control subjects from a cohort of 66,140 participants in the Health Study of Nord-Trøndelag in Norway. Venous thrombosis was validated using standardized criteria for venous thrombosis and pulmonary embolism. Prethrombotic serum anticardiolipin antibodies were measured by an enzyme-linked immunoassay. There was no association between elevated anticardiolipin antibody levels and subsequent venous thrombosis, overall or after stratification by sex, different age groups or idiopathic vs. secondary thrombosis. The overall odds ratio was 1.11 (95% CI: 0.71-1.74) for greater than vs. less than the 95th percentile of anticardiolipin antibody levels. In conclusion, in this general population sample elevated anticardiolipin antibody levels was not a risk factor for subsequent venous thrombosis.

Adult↗
PubMed1998

Chronic hypoglycaemia in a hunting dog due to secondary hypoadrenocorticism.

A six-year-old neutered female pointer was referred for evaluation of seizures that occurred only in association with exercise. A tenacious ocular discharge was also evident and tear production was decreased bilaterally. Diagnostic testing revealed severe hypoglycaemia caused by secondary hypoadrenocorticism. Treatment was instituted with prednisone (5 mg, orally, once daily) and the seizures ceased. Tear production returned to normal without additional treatment. Glucocorticoid deficiency should be considered a cause of hypoglycaemic seizures once other, more common, causes have been ruled out.

Adrenal Insufficiency↗
PubMed2001

The hunt for a cure for Parkinson's disease.

Several exciting new scientific advances have been made in the past decade toward both understanding the causes of and finding a cure for Parkinson's disease. Heartened by an acceleration in research findings in the past several years, the government has recently called for an infusion of funds from both the National Institutes of Health and private foundations into this burgeoning area of biomedical research. Most currently available conventional treatments for the disease only temporarily delay symptom presentation while doing nothing to halt disease progression. However, the rapidly accelerating pace of research in this field has left researchers hopeful that Parkinson's will be the first major age-related neurodegenerative disease for which we have a viable cure. In this article, advances in various areas of Parkinson's disease research are reviewed.

Animals↗