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860 records · Page 48Linked to original sources
PubMed1995

Oral allergy syndrome successfully treated with pollen immunotherapy.

BACKGROUND: Some patients with allergic rhinitis have oral allergic reactions to fresh fruits and vegetables. This phenomenon has been termed "oral allergy syndrome" and is proposed to be due to cross-reacting allergens in the foods and pollens. METHODS: We report a patient with allergic rhinitis and oral allergy syndrome treated with pollen immunotherapy. Prior to immunotherapy, eating any fresh fruit or vegetable caused immediate itching and swelling of his tongue and throat. Prick skin test titration with pollens and foods was performed before and after 13 months of immunotherapy. Specific IgE immunoassay was performed with the same extracts on serum obtained before and after 7 and 13 months of immunotherapy. IgE immunoblots were performed on the same extracts separated by polyacrylamide gel electrophoresis using sera from the same time periods. RESULTS: After 1 year on immunotherapy, the patient's allergic rhinitis symptoms resolved, and he was able to eat fresh fruits and vegetables without reaction. Skin testing and specific IgE immunoassay demonstrated a marked reduction in sensitivity to not only the pollens but the foods as well. Immunoblots revealed that the intensity of IgE binding to most components of the extracts, some common to pollens and foods, declined during immunotherapy. CONCLUSIONS: These results support the notion that oral allergy syndrome is due to cross-reacting allergens in foods and pollens and may be amenable to treatment with pollen immunotherapy.

Adult↗
PubMedDate not supplied

[Clinico-experimental study of a new antibactorial agent for local use in stomatology].

Tibezonium iodide is a new drug having antibacterial activity for the therapy and the prevention of mouth infections. Before testing its therapeutic efficacy, its effect on the bacterial flora of the human saliva was verified as follows. Salivary samples, collected before and after the administration (double-blind, cross-over) to volunteers, were counted for bacteria. The drug reduced the bacterial count in the saliva with statistical significance in both the pharmaceutical forms. Subsequently the drug was tested in different dental or oral conditions. To 90 patients suffering from marginal paradentitis or other diseases with this type of complications tablets were administered. The results obtained in this group were satisfactory or almost satisfactory in 73.5% of the cases examined. The patients treated with bubble-gums were 70. All of them were suffering from the same kind of disease of the first group; a few of them had alveolitis following tooth extraction. The results in these subjects were satisfactory or almost satisfactory in 77% of the cases examined. Tibezonium proved to be particularly effective in marginal paradentitis and in piorrhoic paradontosis. Bubble-gums should not be used in subjects with dental mobile prosthesis.

Adolescent↗
PubMed1993

Faulty conclusion.

Explore the source record for details and available documents.

Glossitis, Benign Migratory↗
PubMed1995

Periodontal and soft-tissue abnormalities.

Young children come to our offices with a variety of periodontal and soft-tissue abnormalities, which require accurate diagnosis, treatment or reassurance, and possible referral to our medical colleagues. Periodic review of soft-tissue lesions can help the dental team to recognize both common and rare abnormalities affecting young children. Recent years have brought new insights into the etiology and treatment of periodontal diseases of children, making it possible to prevent or treat many formerly untreatable conditions.

Child, Preschool↗
PubMed1977

Recognizing the allergic person.

Recognition of the allergic individual is facilitated by an awareness of certain characteristic actions and various facial lesions which may be clues to other allergic problems. A gaping expression, clearing of the throat and rubbing or mashing of the eyes and nose may indicate significant rhinitis. Dark circles and bags under the eyes, long, silky eyelashes and injected conjunctivas are other signs. Bruxism and malocclusion may also be related to an allergic diathesis.

Adolescent↗
PubMed1993

Expression of intermediate filaments in human tongue mucosa.

The specific inflammatory lesions of the human tongue, namely fissured tongue and geographic tongue, have been found to differ clinically and histologically from each other and from healthy appearing tongue (control). In this study we describe expression of cytokeratin, vimentin and desmin intermediate filaments in these tongue forms. The most important findings were seen in fissured tongue; strong positive staining of cytokeratin proteins indicate the incomplete keratinization of the epithelium, vimentin staining was irregular indicating subepithelial edema and desmin expression showed the destruction of the uppermost muscle cells. The corresponding changes of geographic tongue were similar but slight when compared with those of fissured tongue. Different immunohistochemical methods can supplement the information obtained from tongue biopsies by conventional methods and lead to a better understanding of the morphology of the tongue mucosa.

Adult↗
PubMed1976

The mouth in health and disease.

Medical, dental and psychiatric conditions may cause dysfunction of the mouth in health and disease. The principle of clinical assessment of the patient, which includes a thorough assessment of the physical, social and psychological factors, is of paramount importance. This paper has attempted to describe some of the more common conditions affecting the mouth in general practice, and to underline important causes of pain which can occur in the face arising from conditions in the mouth.

Candidiasis, Cutaneous↗