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Codeine self-medication in a headache patient.

Self-medicating behavior for the treatment of headaches is a widespread phenomenon with costly and hazardous consequences. The case presented illustrates the ramifications of such behavior and suggests an integrated approach to the management of headaches. Biological mechanisms for the aggravation of headaches by self-medication are discussed and integrated with psychological observations. The existing epidemiologic studies of self-medication are reviewed and reveal a need for further studies, particularly in the United States.

Analgesics, Opioid↗

Utilization of thin-layer chromatography and enzyme immunoassay systems to screen and confirm the presence of morphine, codeine, phencyclidine and benzoylecgonine.

Thin-layer chromatography (TLC) and enzyme immunoassay (EMIT) were coordinated to produce unequivocal identification of certain substances. Samples were extracted and subjected to TLC. After development, "positive" spots were scraped from the plate, buffered, centrifuged, and subjected to EMIT. Interferences were not encountered.

Analgesics, Opioid↗