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The role of polyneuropathy in motor convalescence after prolonged mechanical ventilation.

OBJECTIVE: To test the hypothesis that prolonged motor recovery after long-term ventilation may be due to polyneuropathy and can be foreseen at an early stage by electromyography (EMG). DESIGN: Cohort study with an entry period of 18 months. Polyneuropathy was identified by EMG studies in the intensive care unit (ICU). During a 1-year follow-up, amount of time was recorded to reach a rehabilitation end point. SETTING: The general ICU of a community hospital. PATIENTS: Fifty patients younger than 75 years who were receiving mechanical ventilation for more than 7 days. MAIN OUTCOME MEASURES: A rehabilitation end point was defined as return of normal muscle strength and ability to walk 50 m independently. RESULTS: In 29 of 50 patients, an EMG diagnosis of polyneuropathy was made in the ICU. Patients with polyneuropathy had a higher mortality in the ICU (14 vs 4; P = .03), probably related to multiple organ failure (22 vs 11; P = .08) or aminoglycoside treatment of suspected gram-negative sepsis (17 vs 4; P = .05). Rehabilitation was more prolonged in 12 patients with polyneuropathy than in 12 without polyneuropathy (P = .001). Of nine patients with delays beyond 4 weeks, eight had polyneuropathy, five of whom had persistent motor handicap after 1 year. In particular, axonal polyneuropathy with conduction slowing on EMG indicated a poor prognosis. CONCLUSIONS: Polyneuropathy in the critically ill is related to multiple organ failure and gram-negative sepsis, is associated with higher mortality, and causes important rehabilitation problems. EMG recordings in the ICU can identify patients at risk.

APACHE↗

[A multimodality method for the rehabilitation of myocardial infarct patients with a hyperkinetic type of hemodynamics during convalescence].

120 postmyocardial infarction patients with hyperkinetic hemodynamics have taken iodine-bromine baths, received beta-adrenoblockers and undergone electric sleep. The treatment effects on central hemodynamics, vegetative tone and collagen formation allowed the authors to develop a procedure combining physical factors and beta-adrenoblockers which proved advantageous for postmyocardial infarction patients.

Adrenergic beta-Antagonists↗

[Detection of convalescent Vibrio cholerae carriers using the enterotest].

Although the existence of chronic carriers of Vibrio cholerae has been posited, the information in this regard is limited and contradictory. In order to determine the usefulness of the encapsulated string test (enterotest) for detecting V. cholerae in duodenal secretions of biliary origin (biliduodenal secretions), 59 patients (30 males and 29 females) over the age of 15 with clinically and bacteriologically diagnosed cholera were evaluated. All the patients, who were treated at the María Auxiliadora Departmental Hospital in Lima, Peru, were put on the same rehydration regimen and were given 2 g of tetracycline daily for 3 days. Between 24 h and 7 days after completion of the antibiotic treatment the first control tests were performed: culture of biliduodenal secretions obtained using enterotest and culture of feces obtained by rectal swab. No patient had diarrhea at the time of the first test. The biliduodenal secretion cultures revealed the presence of V. cholerae in five patients (8.5%) (four females and one male), while the fecal culture yielded negative results in all cases. One week later the control test was repeated on four of the five patients. All the biliduodenal secretion cultures were negative and only one fecal culture was positive at this stage. The patient in question was subjected to the same control tests one week later and both were negative. It is concluded that enterotest can be a simple, well-tolerated, low-cost method for detecting V. cholerae carriers.

Adolescent↗

[The clinical course of the immediate and late convalescent periods in viral meningoencephalitis].

The frequency and severity of residual phenomena after viral meningoencephalitis is to large degree determined by the premorbid background, etiology, severity of the acute period of the disease hospitalization terms. Among the residual phenomena functional disorders are more frequent while organic are rare and regress within 1.5-2 years. Complete cure of the patients should therefore be 1.5-2 years after discharge from the hospital.

Adenovirus Infections, Human↗

How long do patients convalescence after inguinal herniorrhaphy? Current principles and practice.

Over the course of this century it has become apparent that there is no longer any rationale behind the old-established advice to rest for several weeks after hernia repair. It was our impression that such advice continues to be widely accepted, and we therefore sent questionnaires to 100 recently appointed consultant surgeons, 400 of their patients and 200 recently established partners in general practice to assess current practices. Our findings show that surgeons advised a mean of 4.4 weeks off work and GPs 6.2 weeks off-work, in both cases the period varying with the nature of the patient's occupation. Patients actually took a mean of 7.0 weeks off work. The wide variation reflects the lack of evidence that an early return to work after hernia repair causes any detrimental effect. We believe that this should be explained to patients, who should be free to return to work as soon as they feel comfortable. Such a policy could substantially decrease the current loss of productivity.

Convalescence↗

[Behavior therapy of schizophrenia patients during convalescent period].

58 of schizophrenia patients at restoration stage in the hospital were studied. The ineffective adaptive behaviors were assessed and behavior therapy plans were made. The behavior therapy was provided in group or individually. The result indicated that patients' ineffective adaptive behaviors such as laziness, passive, withdrawal, role conflict, sexual dysfunction, ineffective adaptation in the society, and aggressive were improved a lot than those before receiving therapy (P < 0.01).

Adaptation, Psychological↗