Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CASTS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 865 records · Page 48Linked to original sources

Protein composition of urinary casts from healthy subjects and patients with glomerulonephritis.

Urinary casts from 46 healthy volunteers and 60 patients with glomerulonephritis were examined for the presence of Tamm-Horsfall glycoprotein and other proteins. All samples gave immunofluorescence evidence of Tamm-Horsfall protein in casts. Casts from 59 of the patients but only three of the controls contained other proteins in addition (p less than 0.001). Immunoglobulins (IgG, IgM, IgA) were detected in casts from 53 of the patients but none of the healthy volunteers. Examination of urinary casts for immunoglobulins, complement, and fibrin provides a non-invasive method for distinguishing patients with active glomerular disease.

Complement Activating Enzymes↗

Technique for making hollow central airway casts.

We have developed a method for producing rigid hollow casts of the central airways. Woods metal (melting point 70 degrees C) was poured into the airways at the trachea of an excised canine lung air-dried at a transpulmonary pressure of 30 cmH2O. The tissue was dissolved and removed, and the resulting negative cast was carefully trimmed leaving only airways with a diameter of 2 mm or greater. The cast was then electroplated with copper that provided a rigid jacket encasing the Woods metal. Heating this structure to 100 degrees C liquefied the Woods metal allowing the majority of it to flow out. Residual amounts were readily removed by a high-pressure steam hose attached to the trachea. Comparisons were made between airway diameters from in vivo radiographic bronchograms (DB) and direct measurements of the resulting trimmed Woods metal cast (DC). Linear regression analysis of these data indicated a high degree of correlation (DC = 0.98 DB + 0.03, r = 0.99). We concluded that this technique produces positive casts which provide a good representative model of the central airways.

Animals↗

Airflow characteristics in a baboon nasal passage cast.

Airflow patterns in the nasal passages influence the distribution of air-pollutant-induced lesions in the airway mucosa. Little is known about airflow characteristics of the complex nasopharyngeal airway of humans and experimental animals. Airflow characteristics in the nasopharyngeal airways of an adult male baboon (13.9 kg body wt) were investigated with thermistor probes and the findings compared with flow visualization, using a cinephotographic technique. A clear, acrylic, hollow cast of a baboon nose was made, and thermistor probes were inserted to record air velocity in the cast lumen using a wind tunnel to propel air through the cast. An identical cast was studied by passing water through the cast, with pulses of dye to reveal flow, and cinephotography was used for determination of flow velocities and flow patterns. Flow rates adjusted on the basis of a Reynolds conversion showed good correlations between the two methods, whereas cinephotography revealed areas of turbulence and vortex-like flow not detected by thermistor probes. These results suggest that water flow may provide useful information in complex airways where airflow cannot be determined by other methods.

Animals↗

Comparison of vaginal shapes in Afro-American, caucasian and hispanic women as seen with vinyl polysiloxane casting.

Full vinyl polysiloxane casts of the vagina were obtained from 23 Afro-American, 39 Caucasian and 15 Hispanic women in lying, sitting and standing positions. A new shape, the pumpkin seed, was found in 40% of Afro-American women, but not in Caucasians or Hispanics. Analyses of cast and introital measurements revealed: (1) posterior cast length is significantly longer, anterior cast length is significantly shorter and cast width is significantly larger in Hispanics than in the other two groups and (2) the Caucasian introitus is significantly greater than that of the Afro-American subject.

Black People↗

The CAST (Childhood Asperger Syndrome Test): preliminary development of a UK screen for mainstream primary-school-age children.

The article describes a pilot and follow-up study of the preliminary development of a new tool to screen for Asperger syndrome (AS) and related social and communication conditions (the Childhood Asperger Syndrome Test, CAST) in children aged 4-11 years, in a non-clinical setting. In the pilot study, parents of 13 children with AS and of 37 typically developing children completed the CAST. There were significant differences between the AS and typical sample means. The pilot was used to establish preliminary cut-off scores for the CAST. In the main study, parents of 1150 primary-school-age children were sent the CAST, and 174 took part in the full data analysis. Results suggest that compared with other tools currently available, the CAST may be useful for identifying children at risk for AS and related conditions, in a mainstream non-clinical sample. Further research is ongoing.

Asperger Syndrome↗

The CAST (Childhood Asperger Syndrome Test): test accuracy.

The Childhood Asperger Syndrome Test (CAST) is a parental questionnaire to screen for autism spectrum conditions. In this validation study, the CAST was distributed to 1925 children aged 5-11 in mainstream Cambridgeshire schools. A sample of participants received a full diagnostic assessment, conducted blind to screen status. The sensitivity of the CAST, at a designated cut-point of 15, was 100 percent, the specificity was 97 percent and the positive predictive value was 50 percent, using the group's consensus diagnosis as the gold standard. The accuracy indices varied with the case definition used. The sensitivity of the accuracy statistics to case definition and to missing data was explored. The CAST is useful as a screening test for autism spectrum conditions in epidemiological research. There is not currently enough evidence to recommend the use of the CAST as a screening test within a public health screening programme in the general population.

Asperger Syndrome↗

'Severe' wear challenge to 'as-cast' and 'double heat-treated' large-diameter metal-on-metal hip bearings.

The wear generation of double-heat-treated and as-cast large-diameter metal-on-metal (MOM) hip bearings was investigated using standard- and 'severe'-gait simulations. The test hypothesis was that double heat treatment would change MOM hip wear compared with the as-cast condition. Two groups of high-carbon MOM bearings of 40 mm diameter were manufactured and subjected to either hot isostatic pressing (HIP) and solution annealing (SA) or no heat treatment (as cast). The results showed no statistical difference between the two groups under both running-in and steady state conditions. Even under the most 'severe'-gait simulation published to date, the mean volumetric wear rates were 2.9 and 3.9 mm3 per 10(6) cycles for the HIP-SA and as-cast bearings respectively, showing a ten-fold increase in wear compared with walking. These differences were not statistically different; therefore our hypothesis was negated. Changes in alloy microstructure do not appear to influence the wear behaviour of high-carbon cast MOM articulations with similar chemical compositions. This is in sharp contrast with the published significance of bearing diameter and radial clearance on the wear of MOM hip bearings.

Biocompatible Materials↗

Accuracy of casts produced from alginate and hydrocolloid impression materials.

It is recognized that alginate impression materials have been used to obtain casts from which castings have been fabricated for a number of years. This study indicates that more dimensionally accurate casts are produced from hydrocolloid compared with casts produced from alginate. The most accurate casts were produced from the polyether impression material.

Alginates↗

The effect of axial grooves on the resistance form of cast restorations.

Fifteen sets of castings were fabricated to machined stainless steel dies of 5 degrees, 10 degrees, and 15 degrees of taper and 3, 4, 6, 8, and 10 mm of preparation length. Each casting was loaded vertically on its sloped surface in an attempt to unseat the casting. Only the castings of 3 and 4 mm of preparation length and 10 degrees and 15 degrees taper were unseated. Two experiments were performed on these four sets of dies to test parallel proximal and parallel buccolingual grooves. Dies with grooves oriented on the proximal surfaces provided complete resistance to horizontal dislodgement, whereas dies with grooves oriented on the buccal and lingual surfaces provided only partial resistance to horizontal displacement and potential failure of the castings.

Crowns↗

Excretion of casts and uromucoid in urine after prolonged heavy exercise.

Excretion of uromucoid, albumin and casts in urine were determined in twenty well-trained men, ten aged 20-30 years, and ten aged 50-60 years, before, during and after a 70 km cross country ski race. During the race there was only a slight increase in uromucoid excretion, but a marked increase in the excretion of casts and albumin. The older subjects had a tendency to lower urine output during the race compared to the younger group. Reduction of urine output below ca. 25 ml/h was accompanied by a conspicuous increase in urine cast and albumin concentrations, with only a slight increase in uromucoid concentration, and even a reduction in uromucoid excretion. No significant relationship was found between cast excretion and uromucoid concentration. Thus the gross cylindruria observed during longstanding exercise must be ascribed to other urinary factors facilitating the formation of casts.

Adult↗

Psychometric evaluation of the Children of Alcoholics Screening Test (CAST) in a psychiatric sample.

The Children of Alcoholics Screening Test (CAST) is a 30-item screening instrument developed to identify children who are either living with or have lived with alcoholic parents. In a sample of 250 psychiatric patients, the CAST exhibited substantial item-total scale correlations and a high level of internal consistency reliability. Total CAST scores discriminated self-identified children of problem drinkers from control subjects and were significantly correlated with the severity of parental psychological and social complications due to alcohol misuse. Factor analysis indicated a unidimensional scale structure. CAST cut-off scores produced a low false positive and false negative rate. The psychometric properties of the CAST suggest that it is a useful screening instrument for identifying the offspring of problem drinkers and alcoholics.

Adult↗

Development of a new high-speed measuring system to analyze the dental cast form.

A new non-contact measurement system employing of a line laser and CCD camera was developed to rapidly measure maloccluded dental casts with large depth and high accuracy. In this system, the measuring interval along the line laser and the model scanning direction perpendicular to the line laser were both 0.2 mm. By averaging the raw data through repetitious input and smoothing by local filtering, the noise was effectively decreased. Sub-pixel processing, which calculates the pixel position with the largest brightness within one pixel, improved the accuracy in the measurement to 22 microns compared with 65 microns before sub-pixel processing. Dental casts with malocclusion were measured with this system. The time and the depth for the measurement were about 10 minutes and 60 mm, respectively. This was a vast improvement compared with our previous system employing a point laser. In the CG of the measured dental casts, smooth and detailed surface morphology were sufficiently reproduced, and recognition of the characteristic points in the cast could be accomplished with the accuracy of 30 microns. This measurement system will be helpful to analyze the dental cast form with malocclusion in progress.

Humans↗

Dispersion-casting thin and ultrathin fabric-reinforced silicone rubber membrane for use in the membrane lung.

Pinholes in thin silicone rubber membrane have previously been traced to undispersed silica filer aggregates within the silicone rubber. This was overcome by centrifuging the dispersion to remove the aggregates prior to membrane fabrication. Thin (less than 75 mu) and ultra-thin (less than 25 mum) membrane could then be dispersion-cast. To facilitate handling and to increase mixing of blood in the membrane lung, it is often desirable to reinforce the silicone rubber membrane with fabric. Unfortunately, this process frequently introduces pinholes of its own. We have found than pinhole-free fabric-reinforced silicone rubber membrane can consistently be produced by the double-layer casting technique. First, the dispersion is cast onto aluminum foil, solvent evaporated, and partially cured. A second layer is next cast on top of it, followed by fabric. After solvent evaporation, final cure is under nitrogen using organic peroxide catalysts. This technique has permitted us to consistently cast strong pinhole-free membranes as thin as 9 mu.

Humans↗

Response of three types of cast posts and cores to static loading.

OBJECTIVE: An analysis is made of the influence of continuous compression loading on different types of cast posts and cores and its effects on the crowns and teeth. METHOD AND MATERIALS: Thirty extracted maxillary canines were prepared and divided into three groups (n = 10) according to the type of cast posts and cores used for restoration: chrome-nickel alloy, acetalic resin, and IPS-Empress porcelain. Metallic cast crowns were luted onto the cores. The specimens were evaluated with an Instron testing machine at an angulation of 45 degrees and a forward speed of 0.5 mm/min. After testing, the specimens were sectioned along the axis and examined under x40 magnification. RESULTS: Mean load resistance of the restorations until fracture was 2,120 N, 1,491 N, and 2,139 N in the chrome-nickel, IPS-Empress ceramic, and acetalic resin groups, respectively. CONCLUSION: Significant differences in resistance were observed between metal and porcelain and between resin and porcelain. Microscopically, the apical portion was found to be most affected by fracture and compromised the teeth subjected to chrome-nickel restorations. The metal cast posts and cores exhibited different angulations, while the ceramic restorations showed cracks. The acetalic resin cast posts and cores presented no fractures.

Acetals↗

[The disinfection efficiency comparison of different treatments on dental impression and gypsum casts].

OBJECTIVE: In this study, the disinfecting efficiency of five disinfecting methods to three bacterial: Staphylococcus epidermidis, Streptococcus sanguis and Bacillus subtilis were evaluated. METHODS: Germ free impressions and gypsum casts were divided into three teams contained 16 impressions and 5 gypsum casts for each one. Each team was smeared with each one of the three bacterial solutions. Then four disinfecting methods were administrated on these impressions separately, 2% glutaraldehyde immersion, 2% glutaraldehyde spray, 5% Eric immersion, 5% Eric spray. And ozone treatment was administrated on gypsum casts. Control teams were set up. After the treatment the impressions and gypsum casts were sampled at standard sites. The colonies were counted after culture and were used to deduce the germicidal ratio as the standard of disinfecting efficiency. RESULTS: There was no difference between the efficiencies of five disinfecting methods for Streptococcus sanguis and Staphylococcus epidermidis. But for B. subtilis, the immersion methods have the highest efficiency among the methods and the ozone treatment has the least efficiency. CONCLUSION: 2% glutaraldehyde immersion, spray, 5% Eric immersion, spray are all effective disinfecting methods for impressions and ozone treatment is an effective method in disinfecting the gypsum casts.

Bacillus subtilis↗

Cellular allergen stimulation test (CAST) 2003, a review.

Specific diagnosis of immediate type allergies, such as rhinoconjunctivis, asthma, urticaria/angioedema and anaphylaxis, particularly when IgE-mediated, traditionally rests on prick and/or intradermal skin tests and, since about 30 years, on the determination of allergen specific IgEs. Some cellular tests, i.e. tests determining the reactivity of blood cells in vitro, particularly basophils, to allergens, have been available for many years. The determination of histamine release has been widely used in allergy pathophysiological research but its routine application in allergy diagnosis has been restricted to few groups. Basophil degranulation, as determined by microscopic examination, was promoted by some groups in the 1980's but has been largely abandoned since around 10 years ago; an alternative cellular test, based on the determination of sulfidoleukotrienes (LTC4, LTD4, LTE4) produced by IL-3 primed basophils stimulated by allergens in vitro, has been proposed. This test became available commercially in 1993 under the name of CAST (Bühlmann Laboratories, Allschwil, Switzerland). The CAST assay has been used in allergy diagnosis in a variety of indications, such as inhalation allergies, allergies to insect venoms, foods, occupational allergens and various drugs. A large number of reports on CAST diagnostic value, however, have been anecdotal. A meta-analysis of validated and well controlled studies encompasses 37 studies, 1614 patients and 1145 controls. This should definitely establish the value of this diagnostic test, particularly in instances where other in vitro or in vivo diagnostic tests are not reliable, such as food or drug allergies, as well as in non-IgE-mediated immediate hypersensitivity reactions. However, a number of questions about the CAST diagnostic assay are still open or have not been systematically explored. This may explain, in addition to the practical limitations inherent to all allergy cellular tests, why CAST has not yet become a very widely used assay worldwide, having gained broad acceptance in some countries but not in others.

Allergens↗

Calf antibiotic and sulfonamide test (CAST) for screening antibiotic and sulfonamide residues in calf carcasses.

The Calf Antibiotic and Sulfonamide Test (CAST), a microbial inhibition screening test, was developed for detecting antibiotics and sulfonamides in bob veal calf carcasses. The test uses Bacillus megaterium ATCC 9885 as the indicator organism and Mueller Hinton agar as the growth medium. Compared to Swab Test on Premises (STOP), developed in 1970, this screening test has higher sensitivity and the ability to detect a wider range of veterinary antimicrobial residual drugs, particularly sulfonamides, at lower concentrations. Carcasses that are tested with CAST and suspected of containing chemical residue above tolerance level are retained for confirmation. Disposition of these carcasses are determined upon laboratory result. Routine testing of bob veal calves with CAST allowed the Food Safety and Inspection Service to release most calf carcasses within 24 h post-slaughter, thus conserving shipping and handling resources. However, changes in the regulation in 1990 dictate that disposition of carcasses found to contain violative levels of sulfonamide residues should be based on laboratory findings. The analysis of the data for the years 1990-1994 and 1998 indicate that the use of CAST over the years was significant, and had a direct impact on reduction of residue violations in veal carcasses. With the use of CAST, potentially harmful antimicrobial chemicals entering the human food chain through veal meat have been minimized.

Animals↗

[The manufacture and application of compound cast post-core in maxillary molars].

PURPOSE: To investigate the clinical results of compound cast post-core in maxillary molars. METHODS: Compound cast post-core was used to repair maxillary molars which had wide defects in crowns and had difficulty in finding the common insert path. RESULTS: Compound cast post-cores were used in 32 patients for 35 teeth. Full crown or fixed bridge were then fabricated. There was no post-core lost during a follow up of 1 to 5 years. CONCLUSIONS: Compound casting post-core not only solved the problem of making cast post-core in complex maxillary molars, but also improved the retention of these post-cores and strengthened the restorations by using the undercut area of the teeth.

Crowns↗