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Association between maternal fever and psychological/behavior outcomes: a hypothesis.

BACKGROUND: This study is one of the first to investigate the association between maternal report of fever during middle to late pregnancy and psychological, behavioral, and educational outcomes in offspring. The hypothesis guiding this research was that maternal fever during the second trimester of pregnancy has an adverse effect on the development of the central nervous system (CNS) of the fetus, resulting in abnormalities of psychological development and behavior that can be observed in childhood. METHODS: Multivariate analyses of a birth cohort compared outcomes for children whose mothers never reported fever during pregnancy and those who reported fever in the second and third trimesters. Children were compared on measures of temperament, behavior, and academic performance in infancy and at five and 12 years of age. RESULTS: Associations were obtained for second-trimester fever and distress to novelty (p < 0.05) in infancy. Significant associations were also obtained for inhibition (p < 0.01), negative emotionality (p < 0.05), and lack of task persistence (p < 0.01) at age five. Furthermore, school achievement (p < 0.05) and task orientation (p < 0.01) at age 12 were associated with maternal reports of second-trimester fever exposure. CONCLUSIONS: Much of the gestation/hyperthermia research has focused on the relationship between hyperthermia exposure and profoundly teratogenic outcomes. In this study we investigated subtler psychological/behavioral associations that may not be observable until later in development. Although the current study was hampered by technical limitations, the results support the need for more rigorously controlled research into a possible association between gestational fever and psychological/behavioral outcomes.

Behavior↗

A large-scale survey of eating disorder symptomatology among female adolescents in the People's Republic of China.

OBJECTIVES: This study was designed to document comprehensively the prevalence of the signs, symptoms, and associated features of anorexia nervosa and bulimia nervosa among schoolgirls in the People's Republic of China. METHODS: Female participants were recruited from both junior and senior high schools with varying levels of academic performance in six cities (Beijing, Shanghai, Guangzhou, Zunyi, Xin Xiang, and Yinchuan) that are representative of different geographical regions in China (North East, Central East, South East, South West, North West, and North). In each school, girls were recruited across all grades, in order to cover ages 12-19 years. The final sample comprised 1,246 participants whose mean age was 15.76 years. The questionnaire, developed specifically for the purpose of this research, assessed the diagnostic criteria and associated features of anorexia nervosa and bulimia nervosa outlined in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders. RESULTS AND DISCUSSION: Our results have shown a surprisingly high level of weight-related concerns among schoolgirls across mainland China. There would seem to be few cases of anorexia or bulimia, although some girls satisfy criteria for partial diagnoses. Our findings highlight the difficulty of identifying girls who are underweight, at least by applying the standard Western procedure for categorizing body mass index.

Adolescent↗

Dealing with substance abuse among people with disabilities.

Many persons with physical disability have a hidden disability: substance abuse involving alcohol and/or psychotropic drugs. Patterns of substance abuse behavior vary according to use before disability, following the onset of disability, or both before and following the onset of disability. Substance abuse has a negative impact on a person's vocation, academic performance, family life, and social life, as well as on physical health. Rehabilitation nurses need assessment skills and interventions specifically aimed at dealing with substance abuse.

Adult↗

Neuropsychologic and CT examinations in leukemic patients surviving 10 or more years.

Long-term survivors of childhood leukemia were studied to determine their neuropsychologic status. All had had cranial irradiation 10 or more years before. The results were 1. The IQ and academic performance of 56 cured leukemic patients show no significant difference from the normal population. 2. More exact neuropsychological tests (attention, reaction time, visual-motor coordination, memory) reveal important deficits. 3. The frequency of CT aberrations in 33 study patients was 45% and showed no correlation with either the IQ or other neuropsychological results.

Adolescent↗

Early amplification options.

Children with permanent hearing loss have been remediated with hearing amplification devices for decades. The influx of young infants identified with hearing loss through successful newborn hearing screening programs has established a need for amplification resources for infants within the first six months of life. For the approximately two of every 1000 infants born who are identified with bilateral hearing loss [Mehl and Thomson, 1998, Pediatrics 101, p. e4], the use of amplification is commonly the first step in treating the sequella of their loss. The use of hearing aids, combined with early intervention, has been shown to significantly improve the speech and language skills of young children with hearing loss [Yoshinaga-Itano, 2000, Seminars in Hearing 21, p. 309]. Speech and language delays have contributed to compromised academic performance of school aged children with hearing loss [Johnson et al., 1997, Educational Audiology Handbook, Singular Publishing, San Diego]. Most hard-of-hearing and deaf children use hearing aids and other assistive listening devices every day throughout their lifetime and the life expectancy of a hearing aid is only five to eight years. The current challenge for pediatric audiologists is selecting and evaluating the available amplification to provide the best options for children and their families. Amplification technology has seen an explosion in growth the past few years and the options continue to expand rapidly. This article examines currently available amplification technology and reviews the selection criteria that may be used for infants and young children. Issues such as style, type, amplification features, signal processing strategies, and verification and validation tools are also discussed.

Cochlear Implants↗

Adolescents' coping with surgery for scoliosis: effects on recovery outcomes over time.

Surgery for adolescent idiopathic scoliosis is painful and stressful and has a long and demanding recovery. The purpose of this study was to examine pre- and postoperative avoidant/vigilant coping and long-term activity outcomes through 9 months postsurgery for adolescents (11-18 years, N = 113) undergoing scoliosis surgery. Generally, more vigilant copers (preoperatively and 1 month postoperatively) participated in more activities (usual, new, and social) and had higher academic performance during recovery. Several moderation effects indicated these relationships were stronger for older adolescents and those more internal in locus of control. Adolescents were more vigilant in the hospital, became more avoidant 1 month after surgery, and remained at these levels 6 months postsurgery. Understanding coping processes and individual factors is necessary to develop interventions to help adolescents cope successfully with recovery demands.

Adaptation, Psychological↗

Trisomy 8 mosaicism in chorionic villus sampling: case report and counselling issues.

We report an unusual case involving chorionic villus sampling (CVS) and trisomy 8 mosaicism. CVS showed a normal direct preparation while the culture showed mosaicism for trisomy 8. Subsequent amniocentesis revealed only normal chromosomes. A peripheral blood culture after birth revealed low-level trisomy 8 mosaicism. The patient appeared phenotypically and developmentally normal at 30 months of age. We conclude that prenatal counselling for similar cases needs to include the rare but real possibility that chromosome mosaicism detected prenatally may be found postnatally with largely unknown consequences. Secondly, low-level chromosomal mosaicism may be more common than previously recognized. Thirdly, very low-level trisomy 8 mosaicism may be compatible with a normal phenotype but long-term follow-up is required. And lastly, the use of fetal blood sampling is questionable in these cases because the phenotype may not be accurately predicted. Further studies of such cases are needed to address these important and unanswered issues, including the potential implication of mosaicism on academic performance and cognitive functioning.

Adult↗

Cigarette smoking among schoolboys in Beijing, China.

The current study was designed to assess the recent rate of cigarette smoking and to examine the association of cigarette smoking with individual factors and problem behaviors using data collected in December 1997 from 323 middle school students (43% females) in Beijing, China. About 15% of the study sample (23% males and 5% females) reported having ever smoked. The data in the current study confirmed findings from our earlier study (Li et al., 1996, Substance Use and Misuse, 31, 545-563) that the prevalence of cigarette smoking among Chinese adolescents was higher among males, increased with advancing age and was associated with participation in other problem behaviors and with poorer self-perceived academic performance. The data underscore the need for smoking-prevention programs targeting Chinese children and adolescents.

Adolescent↗

Effectiveness of a universal drug abuse prevention approach for youth at high risk for substance use initiation.

BACKGROUND: Universal school-based prevention programs for alcohol, tobacco, and other drug use are typically designed for all students within a particular school setting. However, it is unclear whether such broad-based programs are effective for youth at high risk for substance use initiation. METHOD: The effectiveness of a universal drug abuse preventive intervention was examined among youth from 29 inner-city middle schools participating in a randomized, controlled prevention trial. A subsample of youth (21% of full sample) was identified as being at high risk for substance use initiation based on exposure to substance-using peers and poor academic performance in school. The prevention program taught drug refusal skills, antidrug norms, personal self-management skills, and general social skills. RESULTS: Findings indicated that youth at high risk who received the program (n = 426) reported less smoking, drinking, inhalant use, and polydrug use at the one-year follow-up assessment compared to youth at high risk in the control condition that did not receive the intervention (n = 332). Results indicate that a universal drug abuse prevention program is effective for minority, economically disadvantaged, inner-city youth who are at higher than average risk for substance use initiation. CONCLUSIONS: Findings suggest that universal prevention programs can be effective for a range of youth along a continuum of risk.

Adolescent↗

The epidemiology of headache among children with brain tumor. Headache in children with brain tumors. The Childhood Brain Tumor Consortium.

In this report we present aspects of the epidemiology of headache (i.e., pain in the head, face, ear, or neck) among children with brain tumors. The data are derived from the 3,291 subjects in the Childhood Brain Tumor Consortium databank. Overall, 62% of the children with brain tumors experienced chronic or frequent headaches prior to their first hospitalization: 58% of children with supratentorial tumors and 70% of children with infratentorial tumors. The relative frequency of headache increased through age 7 and then leveled off regardless of tumor location. For children under age 5, headache rarely had a duration of more than 1 year prior to hospitalization. Among children over age 4, headache duration of at least one year was significantly greater for supratentorial than for infratentorial tumors. Children with a brain tumor and headache had a different distribution of symptoms and neurologic signs than those without headache. Tumor location and headache status were interactively associated with the presence of other symptoms and neurologic signs. Children with headache had a greater number of other symptoms and neurologic signs. Regardless of tumor location among children with headache, nausea or vomiting, papilledema, and hypoactive tendon reflexes were more frequent, while upper extremity weakness, optic atrophy, and irritability were less frequent. Diplopia, coma, stiff neck, anesthesia or hypesthesia, pupillary abnormalities, and abnormalities of personality, academic performance, or speech were associated with headache in children with supratentorial tumors. No specific symptoms or neurologic signs were associated with headache in children with infratentorial tumors. Supratentorial craniopharyngioma, ependymoma, and protoplasmic astrocytoma were associated with significantly high rates of headache as was infratentorial pilocytic astrocytoma.

Adolescent↗

Epidemiology of seizures in children with brain tumors. The Childhood Brain Tumor Consortium.

We examined potential clinical and pathologic correlates of seizures among the 3,291 children in the Childhood Brain Tumor Consortium database. Fourteen percent had seizures prior to their hospitalization for a brain tumor. Among children who had a supratentorial tumor, seizures occurred in 22% of those less than 14 years of age. The prevalence of seizures increased to 68% of older teenagers. Among children with an infratentorial tumor, the prevalence of seizures was relatively constant at 6% over all age groups. The onset of seizures began more than one year prior to surgical tumor removal in over half of the children aged five or more with supratentorial tumors, significantly longer than for those of the same age with infratentorial tumors. Almost all children (98.9%) with an infratentorial tumor and seizures had at least one other symptom and more than three-fourths of them had at least three. Eighty-nine percent of children with a supratentorial tumor and seizures had at least one other symptom and more than one-half had at least three symptoms. Regardless of whether the tumor was above or below the tentorium, confusion or stupor and coma were more common in children with seizures than in children without seizures. Among children with supratentorial tumors, symptoms of a declining academic performance or an abnormality of personality, speech, walking, or sensation were significantly more frequent in children with seizures, while visual symptoms (other than visual loss or diplopia) and nausea or vomiting were less frequent. Among children with supratentorial tumors, those who had seizures were more likely to have paralysis of an arm, hand, or face, confusion or stupor, or coma and less likely to exhibit irritability, papilledema, optic atrophy, decreased visual acuity, pupillary abnormalities, or abducens paresis. Among children with infratentorial tumors, those with seizures were significantly less likely to have truncal ataxia, but more likely to experience confusion, stupor, or coma. In the supratentorial compartment, astrocytoma (nos), protoplasmic astrocytoma, anaplastic astrocytoma, and ependymoma were more frequently associated with seizures than was craniopharyngioma. No infratentorial tumor type was more or less likely to be associated with seizures. All common tumor types that were represented in both the supratentorial and the infratentorial compartment except astrocytoma (nos) were associated with significantly greater rates of seizures when located in the supratentorial compartment. The tumor location with the highest incidence of seizures was, as expected, the superficial cerebrum. More than 40% of the children with such tumors had seizures.(ABSTRACT TRUNCATED AT 400 WORDS)

Adolescent↗

Prenatal hydrocephalus: outcome and prognosis.

The clinical records of 108 infants presenting with hydrocephalus at birth and operated on from 1971 to 1981 were reviewed in order to evaluate the functional results. Premature newborns and spina bifida patients were excluded. Communicated hydrocephalus (39 cases) and aqueductal stenosis (32 cases, excluding 6 X-linked hydrocephalus and 4 toxoplasmoses) were the two main types of hydrocephalus in this series. Eighty-four percent of the infants were operated on before the age of 3 months. The mean follow-up time was 7 years (range 1 to 14 years). The survival rate, calculated by the life table method, was 62% at 10 years. The functional results were evaluated according to intellectual performance, academic level, and psychological status. Of the 75 surviving children, 28% have an I.Q. over 80 and 50% an I.Q. under 60. The mean I.Q. is 54 (range 0 to 130). Of the 52 children who have now reached school age, only 29% have reached a normal academic level. The psychological status is normal or borderline in 46% of the patients. The importance of head enlargement at birth, ventricular size, and the age at the time of surgery are not related to late functional results. The results were best when there were no associated malformations, no shunt infection, when hydrocephalus was due to aqueductal stenosis (excluding X-linked hydrocephalus and toxoplasmosis), or when the first developmental quotient measured at 6 months was over 80.

Age Factors↗

Evaluation of two test-anxiety reduction treatments in a secondary prevention program.

The study evaluated the effectiveness of both a new anxiety management training program and a cognitive modification procedure as part of a secondary prevention effort to identify and treat test anxiety early in the academic career of college students. Subjects were 40 college freshmen who had been identified as high test-anxious in an initial mail-out survey of the Test Anxiety scale. Subjects were randomly assigned to three experimental conditions: anxiety management training, a cognitive modification procedure, and a no-treatment control group. Results indicated that both the cognitive modification and anxiety management training treatments were effective in reducing test anxiety on a posttreatment administration of the Test Anxiety scale. Especially interesting, a significant difference in academic performance emerged between treatment and control groups three semesters after treatment, underscoring the preventive value of the program.

Adaptation, Psychological↗

The functional independence of response latency and accuracy: implications for the concept of conceptual tempo.

Kagan (1965a) developed the concepts of impulsive and reflective cognitive styles (conceptual tempo) to add a new dimension to the understanding and assessment of human intelligence. Although latency (the principal component of conceptual tempo) is negatively correlated with academic performance, it may not be necessary to modify latency in order to modify accuracy.. With 40 disadvantaged preschool children, it was found that reinforcing long latencies in choice tasks did not increase accuracy and vice versa, and that reinforcing both long latencies and accuracy was no more effective than reinforcing accuracy alone. These data were used to question the usefulness of the construct of conceptual tempo.

Achievement↗

A matched-subject comparison of underachievers with normals on intellectual, behavioral, and emotional variables.

Children labeled as underachievers are compared to a matched group functioning normally within the classroom. Factor analyses of the data from several tests reveal that the "normal" children not only have achieved higher academic performance but also have better learning aptitude. The inference may be made that many "underachievers" actually have a low general aptitude when carefully measured.

Achievement↗

Televised classroom events as distractors for reading-disabled children.

Three experiments examined the influence of videotaped classroom events on the academic performance and study behavior of reading-disabled and normally reading children in grades 1 through 6. In experiments 1 and 2a an experimenter-controlled presentation of these distractors resulted in performance decrements, the magnitude of which was greater for higher difficulty tasks. The distractor effects were similar for the two groups in this condition. However, when the children themselves were allowed to control their degree of exposure to the same distractors in experiment 2b, the reading-disabled children were less likely to act to escape the distraction. Results are discussed in terms of children's metacognitive awareness of distraction, and implications for the classroom are considered.

Achievement↗

Marks and classroom adjustment as early indicators of mental health at age twenty.

The data are derived from a 15-year longitudinal study of 659 urban children who entered kindergarten in 1968, 371 who were interviewed at the age of 20. Analyses related school adjustment and academic performance in the early primary grades, early adolescence, and middle adolescence to mental health outcomes based on responses to a short form of the MMPI at age 20. The results suggest that poor marks, absence of positive coping behaviors, and presence of negative coping behaviors are indicators of later mental health problems, that the absence of positive coping behaviors may be more indicative of later problems than the presence of negative coping behaviors, and that there are sex differences in the time periods at which indicators of school productivity are important.

Achievement↗

Measuring depression in children: a multimethod assessment investigation.

The present investigation examined measures for the assessment of depressive symptomatology in children, as well as two related constructs (self-esteem and anxiety). The sample consisted of 166 elementary school children from grades 3 through 6. Two self-report depression measures, the Children's Depression Inventory (Kovacs, 1979) and the Child Depression Scale (Reynolds, in press), as well as anxiety and self-esteem scales, were completed by the children. Parents (mothers and fathers) evaluated their children on the depression and anxiety scales from the Personality Inventory for Children (Wirt, Lachar, Klinedinst, & Seat, 1977), and teachers provided global ratings of depression and academic performance. The results support the reliability and validity of both self-report children depression measures. Data obtained on the parent report measure do not recommend its use at this time for assessing depression in children, while results on teachers' global ratings of depression provide some evidence that teachers may be a good source of information regarding depression in children.

Achievement↗