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Results for “ADRENAL GLAND HYPERFUNCTION”

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At least 865 records · Page 48Linked to original sources
PubMed2001

[Diagnosis and surgical treatment of arterial hypertension of adrenal origin].

230 patients with arterial hypertension of adrenal origin were treated. 205 of them underwent adrenalectomy with surrounding paranephral fat. There were no lethal outcomes. Endogenic adrenocorticism was diagnosed in 134 patients. Cushing's syndrom was in 96 patients, Cushing's disease--in 34, ACTH-ectopic syndrome--in 2, adrenocortical cancer--in 2. Primary hyperaldosteronism was diagnosed in 42 cases: idiopathic hyperaldosteronism in 23 patients, aldosteronproducing adenoma (Conn's syndrome)--in 19. Tumors of chromaffine tissue were defected in 30 patients. All the patients underwent complex examination (hormonal profile, US, CT, MRT, angiography if it was necessary). Symptomatic arterial hypertension of adrenal origin was diagnosed during one year in 10% patients only because of absence of typical clinical picture. Use of complex examination has permitted to make a correct topical diagnosis and to choose optimum treatment policy in all the cases.

ACTH Syndrome, Ectopic↗
PubMed1995

[Adrenalectomy under celioscopy. Experience of 25 operations].

OBJECTIVES: Determine the indications for laparoscopic adrenalectomy on the basis of our experience. METHODS: We performed 25 laparoscopic adrenalectomies for primary hyperaldosteronism (n = 10), non-ACTH-dependent hypercortisolism (n = 6), Cushing's disease (n = 2 including one bilateral operation), pheochromocytoma (n = 1) and tumoral formation (n = 5). RESULTS: The operation required conversion to an open procedure in 4 cases (16%). The post-operative period was uneventful in 19 and was clearly less painful. Improved delay to normal intestinal function and rapid return to normal activities was also beneficial in these patients with no parietal damage. Complications occurred in two cases: one local asymptomatic collection and one localized pancreatitis requiring surgical drainage of an abscess. COMMENTS: Compared with our experience with open procedures, the inconvenience of a long laparoscopic procedure (2h 45 min for unilateral adrenalectomy), is counterbalanced by the reduction in risk to complications in 64% of the cases due to the simplicity and lack of parietal damage. We currently propose the laparoscopic procedure for tumours under 6 cm in diameter and for certain pheochromocytomas and rely on the open procedure for proven or suspected corticoadrenalomas.

Adrenal Gland Neoplasms↗
PubMed1993

Hyperadrenocorticism associated with adrenocortical tumor or nodular hyperplasia of the adrenal gland in ferrets: 50 cases (1987-1991).

Adrenocortical adenoma, nodular hyperplasia, or carcinoma was diagnosed in 50 ferrets. Thirty-five (70%) ferrets were female and 15 (30%) were male. The mean age at which clinical signs were first noticed was 3.4 years (range, 1 to 7 years). Clinical signs included large vulva (n = 31; 89% of females), alopecia (n = 43; 86%), pruritus (n = 20; 40%), and increased consumption of water and increased urine output (n = 4; 8%). A mass was palpated at the cranial pole of the kidney during physical examination of 17 (34%) ferrets. Ultrasonography, performed on 39 of 50 ferrets, revealed a unilateral adrenal gland mass in 19 (49%). Four ferrets were anemic, and 2 ferrets were thrombocytopenic. Baseline plasma concentrations of cortisol and corticosterone were within or below the reference range in all 17 ferrets tested, whereas baseline plasma estradiol concentrations were high in 4 of the 11 ferrets (36%) tested. AFter adrenocorticotropic hormone (ACTH) administration, only 1 ferret had a slightly exaggerated response on the basis of plasma cortisol concentrations, and all 17 had normal responses on the basis of plasma corticosterone concentrations. There was little or no increase in plasma estradiol concentrations after ACTH administration. Of the 50 ferrets, 39 were treated by adrenalectomy. Unilateral adrenalectomy was performed in 34 ferrets in which 1 adrenal gland was large, whereas subtotal bilateral adrenalectomy was performed in 5 ferrets with bilateral adrenal disease. Five ferrets died in the immediate postoperative period, and follow-up information was available for the remaining 34, 1 to 34 months after surgery.(ABSTRACT TRUNCATED AT 250 WORDS)

Adrenal Cortex Neoplasms↗
PubMed1979

Familial pheochromocytoma: a report of 2 cases in a kindred.

A kindred with 2 current cases of pheochromocytoma is reported. The proband had classical features of adrenal medullary hyperfunction, in addition to Raynaud's phenomenon. After surgical removal of the right adrenal gland, containing a pheochromocytoma and a small paraganglioma, the patient was free of symptoms. The 12-year-old son of the proband was discovered to have relatively asymptomatic sustained hypertension on routine examination. Biochemical and radiological tests confirmed the diagnosis of a left adrenal pheochromocytoma, which was removed successfully.

Adrenal Gland Neoplasms↗