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Autokinetic movement and inverted vision.

It was considered that inverted vision could influence the condition of the subject's relative framework. The aim of this study was to investigate whether autokinetic movement observed during inverted vision might differ from that in normal vision. One subject wearing inverting spectacles and another one subject in normal vision observed autokinetic movement for five days. The results showed that directional changes increased with the time spent in visual inversion, while in normal vision such tendency was not observed. One speculative interpretation was suggested in terms of subject-related framework.

Adult↗

Comparative study of eye movements in extent of central and peripheral vision and use by young and elderly walkers.

This study compares the visual abilities of young and elderly groups while walking, focusing on differences in the ranges and velocities of eye movements and on differences in the extent and use of their central and peripheral vision. On the basis of two experiments, the following differences between young and elderly walkers in the use of vision, as well as the effect of these differences on walking cadence (the number of steps per minute) were clarified. Elderly subjects depended more on central vision than younger subjects while they were walking, and their walking cadences were hindered by limited visual range. In contrast, younger subjects made use of both their central and peripheral vision while walking; the clarity of peripheral vision gave them greater control over the process of their walking than elderly subjects had.

Adult↗

Intersensory conflict between vision and touch: the response modality dominates when precise, attention-riveting judgments are required.

In four experiments, reducing lenses were used to minify vision and generate intersensory size conflicts between vision and touch. Subjects made size judgments, using either visual matching or haptic matching. In visual matching, the subjects chose from a set of visible squares that progressively increased in size. In haptic matching, the subjects selected matches from an array of tangible wooden squares. In Experiment 1, it was found that neither sense dominated when subjects exposed to an intersensory discrepancy made their size estimates by using either visual matching or haptic matching. Size judgments were nearly indentical for conflict subjects making visual or haptic matches. Thus, matching modality did not matter in Experiment 1. In Experiment 2, it was found that subjects were influenced by the sight of their hands, which led to increases in the magnitude of their size judgments. Sight of the hands produced more accurate judgments, with subjects being better able to compensate for the illusory effects of the reducing lens. In two additional experiments, it was found that when more precise judgments were required and subjects had to generate their own size estimates, the response modality dominated. Thus, vision dominated in Experiment 3, where size judgments derived from viewing a metric ruler, whereas touch dominated in Experiment 4, where subjects made size estimates with a pincers posture of their hands. It is suggested that matching procedures are inadequate for assessing intersensory dominance relations. These results qualify the position (Hershberger & Misceo, 1996) that the modality of size estimates influences the resolution of intersensory conflicts. Only when required to self-generate more precise judgments did subjects rely on one sense, either vision or touch. Thus, task and attentional requirements influence dominance relations, and vision does not invariably prevail over touch.

Adult↗

The role of central and peripheral vision in perceiving the direction of self-motion.

Three experiments were performed to examine the role that central and peripheral vision play in the perception of the direction of translational self-motion, or heading, from optical flow. When the focus of radial outflow was in central vision, heading accuracy was slightly higher with central circular displays (10 degrees-25 degrees diameter) than with peripheral annular displays (40 degrees diameter), indicating that central vision is somewhat more sensitive to this information. Performance dropped rapidly as the eccentricity of the focus of outflow increased, indicating that the periphery does not accurately extract radial flow patterns. Together with recent research on vection and postural adjustments, these results contradict the peripheral dominance hypothesis that peripheral vision is specialized for perception of self-motion. We propose a functional sensitivity hypothesis--that self-motion is perceived on the basis of optical information rather than the retinal locus of stimulation, but that central and peripheral vision are differentially sensitive to the information characteristic of each retinal region.

Adult↗

A new night vision disturbances parameter and contrast sensitivity as indicators of success in wavefront-guided enhancement.

PURPOSE: To determine the level of success of wavefront-guided repair of night vision disturbances after conventional (Munnerlyn) myopic LASIK using a new parameter to describe higher order aberrations, and to compare the improvements to matched myopic LASIK controls who were symptom-free. METHODS: We developed a single parameter metric to represent raw spherical aberration (RAWS) to functionally describe the cumulative spherical aberration for an eye over a range of physiological pupil sizes. To derive the RAWS parameter, spherical aberration is plotted over pupil analysis zones from 3000 to 6000 microm. The RAWS parameter (unit = microm2) is then equal to the area under the plot. Sixteen eyes treated for night vision disturbances by wavefront-guided repair were each compared to the mean of four matched control eyes (total 64 eyes) treated by aspheric myopic ablation and without night vision disturbances. Contrast sensitivity and RAWs parameter for spherical aberration were determined for each of the repair eyes and control eyes before and after surgery. RESULTS: Following wavefront-guided repair, 76% of eyes were subjectively reported to have night vision disturbances improved by at least 80%. The percentage of eyes within normal contrast range increased from 25% to 80% following wavefront-guided repair (P < .05). For the control eyes, LASIK increased RAWS by 126% (RAWS was 122 microm2 preoperatively and 276 microm2 postoperatively). For the night vision disturbances repair eye group, RAWS at presentation was 104% (563 microm2) above the respective postoperative RAWS control eyes. Following wavefront-guided repair, RAWS was decreased (P < .05) to only 49% (410 microm2) above the postoperative control group. CONCLUSIONS: The RAWS parameter enabled a single digit descriptor of overall higher order aberrations for an eye over the principal physiological pupil range. By comparing RAWS parameter changes in wavefront-guided repair eyes to matched postoperative asymptomatic eyes, we were able to determine the magnitude of the deficit in the symptomatic eyes and the relative efficacy of wavefront-guided repair.

Contrast Sensitivity↗

[Quality system Vision 2000].

A recent document of the Italian Ministry of Health points out that all structures which provide services to the National Health System should implement a Quality System according to the ISO 9000 standards. Vision 2000 is the new version of the ISO standard. Vision 2000 is less bureaucratic than the old version. The specific requests of the Vision 2000 are: a) to identify, to monitor and to analyze the processes of the structure, b) to measure the results of the processes so as to ensure that they are effective, d) to implement actions necessary to achieve the planned results and the continual improvement of these processes, e) to identify customer requests and to measure customer satisfaction. Specific attention should be also dedicated to the competence and training of the personnel involved in the processes. The principles of the Vision 2000 agree with the principles of total quality management. The present article illustrates the Vision 2000 standard and provides practical examples of the implementation of this standard in cardiological departments.

Italy↗

Heritability of defects of far vision in young adults--a twin study.

A questionnaire to study defects in far vision in the Finnish Twin Cohort Study was sent to 600 twin pairs of 30 and 31 years of age divided equally by gender and zygosity. An excess in female prevalence of defects in far vision was observed (p less than 0.001). Validation of the questionnaire method to assess negative spherical equivalent of refraction was performed by asking the twins to send their last prescription for glasses. Accuracy of the questionnaire method to detect in far vision was tested using a subsample of cases where actual refraction obtained from the prescription for glasses was available. This actual refraction value was compared with the individuals answers to the questions of far vision. Of the subjects 5.5% were false negatives and 1.8% of the individuals were false positives. In 152 pairs one or both twins had a defect in far vision. Under a threshold liability model, the proportion of total (phenotypic) variance in liability attributable to additive genetic effects was 0.91 in this twin data, while no evidence for effects due to dominance was found.

Adult↗

A machine vision system with CCD cameras for patient positioning in radiotherapy: a preliminary report.

PURPOSE: To determine positioning accuracy of a machine vision system in radiotherapy. MATERIALS AND METHODS: The machine vision system was composed of 640 x 480 pixel CCD cameras and computerized control systems. For image acquisition, the phantom was set up for the reference position and a single CCD camera was positioned 1.5 m from the isocenter. The image data of the fiducial marker with 1.5 mm lead pellet on the lateral surface of the phantom was captured onto the CCD, and then the position of the marker was accurately calculated. The phantom was moved 0.25, 0.50, 0.75, 1.00, 2.00, and 3.00 mm from the reference position, using a micrometer head. The position of the fiducial marker was analyzed using a kilo-voltage fluoroscopic imaging system and a machine vision system. RESULTS: Using fluoroscopic images, the discrepancy between the actual movement of the phantom by micrometer heads and the measurement was found to be 0.12 +/- 0.05 mm (mean +/- standard deviation). In contrast, the detection of the movement by the machine vision system coincided with the discrepancy of 0.0067 +/- 0.0048 mm. CONCLUSION: This study suggests that the machine vision system can be used to measure small changes in patient position with a resolution of less than 0.1 mm.

Head↗

Visual evoked potentials through night vision goggles.

Night vision goggles (NVG's) have widespread use in military and civilian environments. NVG's amplify ambient illumination making performance possible when there is insufficient illumination for normal vision. While visual performance through NVG's is commonly assessed by measuring threshold functions such as visual acuity, few attempts have been made to assess vision through NVG's at suprathreshold levels of stimulation. Such information would be useful to better understand vision through NVG's across a range of stimulus conditions. In this study visual evoked potentials (VEP's) were used to evaluate vision through NVG's across a range of stimulus contrasts. The amplitude and latency of the VEP varied linearly with log contrast. A comparison of VEP's recorded with and without NVG's was used to estimate contrast attenuation through the device. VEP's offer an objective, electrophysiological tool to assess visual performance through NVG's at both threshold and suprathreshold levels of visual stimulation.

Contrast Sensitivity↗

Comparison between "readables" aspheric spectacle lenses and conventional spherical spectacle lenses for overcorrection of presbyopic single-vision contact lens wearers.

Binocular spectacle overcorrection for near with "Readables" progressive-addition lenses and with lenses having spherical surfaces were compared by 36 successful presbyopic wearers of single-vision contact lenses. The two forms of near correction were each worn by these subjects for 3 weeks in a randomized cross-over study and were also directly compared for 1 week in which both overcorrections were available. "Readables" spectacle correction was significantly better than the conventional overcorrection in four of the five patient response categories studied (visual comfort, close vision, intermediate vision, and function without removal) and was not significantly different in one of the five categories (ability to adapt). When asked to choose between the two near corrections, 81 percent of the subjects (29 of 36) preferred their "Readables" spectacles. It appears that "Readables" spectacle lenses offer a viable alternative to single-vision lenses when used for near correction of presbyopic patients wearing single-vision contact lenses for distance correction.

Adult↗

Urinary glucose testing inaccuracies among diabetic patients. Effect of acquired color vision deficiency caused by diabetic retinopathy.

The performance of two urinary glucose tests (Clinitest and Diastix) and several color vision and lightness discrimination tests was assessed in 43 diabetic patients and 43 age-matched controls. Most of the diabetics had proliferative diabetic retinopathy, with normal or mildly reduced visual acuity. The diabetics made significantly more errors on color interpretation of the urinary test results than did controls. The extent of errors for both diabetics and controls correlated with the severity of color vision deficiency but not with lightness discrimination deficiency. The diabetics' performance of the Clinitest test and, to a lesser extent, of the Diastix test was significantly better in bright light than in dimmer light. The type of color vision deficiency among most of the diabetics was characteristic of the acquired blue-yellow defect associated with diabetes mellitus. All of the color vision tests enabled identification of patients likely to make a large number of urine-testing errors with high sensitivity and fairly high specificity.

Adult↗

Color vision defects in early diabetic retinopathy.

Four color vision tests were used to assess color vision in 51 insulin-dependent diabetic patients and 41 normal controls. Right and left eyes of diabetic patients, selected because they had minimal retinopathy, had significantly more color vision defects than controls on Lanthony desaturated D-15, Farnsworth-Munsell 100-Hue, and chromagraph tests. The 100-Hue scores were significantly higher in both right and left eyes of diabetic patients than in controls. There were no significant associations between presence or absence of a color vision defect and age, sex, age at onset, duration of diabetes, or its metabolic control.

Adult↗

Color vision defects in sickle cell anemia.

The Farnsworth-Munsell 100-hue test was used to compare color vision in patients with sickle cell anemia, 20/20 visual acuity, and mild to severe peripheral retinopathy, but without posterior retinal vessel involvement, with matched normal controls. Patients with sickle cell anemia had significantly more blue-yellow and mixed color vision defects and significantly higher Farnsworth-Munsell 100-hue scores than did controls. There were no significant associations between color vision defects and the severity of peripheral retinal findings or the diameter of the foveal avascular zone. These results suggest that color vision defects may exist in patients with sickle cell anemia in the absence of ophthalmoscopic retinal changes in the posterior fundus.

Adult↗

Reversible color vision loss in occupational exposure to metallic mercury.

Color vision was evaluated in twenty-one mercury exposed workers and referents matched for sex, age, tobacco smoking, and alcohol habits. The Lanthony 15 Hue desaturated panel (D-15 d) was applied. In the workers, mean urinary Hg (HgU) was 115+/-61.5 microg/g creatinine; in all but one the values exceeded the biological limit (BEI) proposed by the American Conference of Governmental Industrial Hygienists. A dose-related subclinical color vision impairment was observed in Hg-exposed workers compared to the referents. Just after the survey, working conditions were improved. Twelve months later the workers were reexamined. Mean HgU was 10.0 microg/g creatinine and in no subjects was the BEI exceeded. Color perception was significantly improved compared to the first examination and, furthermore, no differences were observed between exposed workers and referents. The results add evidence that the color vision loss observed during the first part of the study was related to Hg exposure and, moreover, show that this effect is reversible. These data indicate that metallic Hg can induce a reversible impairment in color perception. This suggests that color vision testing should be included in studies on the early effects of Hg. The possibility of applying the D-15 d as an early effect index in the biological monitoring of Hg exposed workers should also be entertained.

Adult↗

Printed cards for measuring low-vision reading speed.

There is a growing consensus that clinical evaluation of the real-world consequences of eye disease requires new performance-based tests. This is because Snellen acuity and other common clinical tests are often poor predictors of everyday function. Ahn and Legge [(1995) Vision Research, 35, 1931-1938] validated a computerized test of reading speed by showing that it provides an accurate prediction of low-vision reading performance with magnifiers. Here, we describe development of a printed-card version of the test suitable for clinical use. This printed-card test retains key design features of the validated computerized test, including the same set of sentences and display format. Data from 23 low-vision subjects showed that a very simple testing procedure using printed cards and a stop watch could be used effectively to estimate reading speed. Reading speed based on a single card was quite accurate (SD equal to about 18% of the mean) and showed no practice effects from one card to the next. Reading speeds obtained with printed cards correlated highly (r = 0.887) with those from computerized testing. We conclude that a simple test, using printed cards, can be used to obtain useful estimates of low-vision reading speed.

Adult↗

Quality of vision after AMO Array multifocal intraocular lens implantation.

PURPOSE: To evaluate safety and efficacy of Array SA40N multifocal intraocular lens (IOL) (AMO) implantation in cataract surgery. SETTING: Helsinki University Eye Hospital, Helsinki, Finland. METHODS: In this prospective randomized comparative trial, 80 patients scheduled for cataract surgery were selected based on preoperative counseling and randomized to have multifocal or monofocal IOL implantation. Fifty-three eyes of 35 patients received a multifocal IOL and 67 eyes of 40 patients, a monofocal IOL. The incidence of complications and visual outcome in the multifocal and monofocal IOL groups were compared. Quality of vision was measured by comparing the severity of visual symptoms (glare, halos, and cataract symptoms score), changes in functional impairment measured by a 7-item visual function test (VF-7), changes in global measures of vision (trouble and satisfaction with vision), and range of accommodation and contrast sensitivity. RESULTS: Intraoperative and postoperative complications and adverse events were few and required no further surgical intervention. Both distance and near visual acuities were significantly better in the multifocal group than in the monofocal group; the difference was most prominent in distance corrected near acuity (P<.001). Thirty-five eyes (67.3%) in the multifocal group and 10 eyes (14.9%) in the monofocal group achieved a distance corrected near acuity of J6 (20/40) or better; 30 eyes (56.6%) and 19 eyes (28.4%), respectively, achieved a best corrected distance acuity of 20/20 or better. Glare symptoms decreased postoperatively in both groups but were slightly more common in the multifocal group. In contrast, halos were significantly more common at 1 month in the multifocal group (P<.001). Contrast sensitivity values were slightly lower with multifocal IOLs at almost all spatial frequencies, but the difference was not significant. The change in the quality of life postoperatively, measured with the VF-7, was significant and identical in both groups. CONCLUSIONS: Pseudophakic eyes with multifocal IOLs had better distance and near acuity and range of accommodation than eyes with a monofocal IOL. Slightly lower contrast sensitivity and increased perception of halos by subjects with the multifocal IOL appear to be an acceptable compromise to enhanced near and distance vision.

Accommodation, Ocular↗

A prospective study of the EYEPORT vision training system.

BACKGROUND: The purpose of this study was to determine if vision training with the EYEPORT system affects vision and reading performance. (Subsequent to this study, the "E.Y.E." has been renamed "EYEPORT") METHODS: College students with normal vision (n = 31) participated in a blind, crossover study to assess within-subject and between-group effects of EYEPORT training. Half the subjects initially underwent training (10 minutes per day, 6 days a week for 3 weeks), and then crossed over to the no-train control condition (3 weeks); the other half underwent the reverse sequence. Vision and reading performance were assessed at baseline, 3 weeks, and 6 weeks. RESULTS: Multivariate analyses (Hotelling's T2) found small improvements in vergence and accommodative facility, reading performance, and stereopsis response time after EYEPORT training (P < 0.025). Enhancements in reading performance and vergence facility were still present 3 weeks after cessation of training (P < 0.001). CONCLUSIONS: The EYEPORT training system shows potential to enhance visual performance and reading ability. Studies are underway to assess its efficacy in symptomatic populations.

Accommodation, Ocular↗

Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma.

BACKGROUND AND PURPOSE: To report on the efficacy and follow-up of 23 patients with primary optic nerve sheath meningioma (ONSM) with fractionated stereotactic conformal radiotherapy (SCRT). PATIENTS AND METHODS: Between 1996 and 2003, 23 patients ( = 23 eyes) with ONSM were treated. Indications for primary stereotactic radiotherapy were tumour progression documented by imaging or symptoms (loss of vision, pain). All patients received SCRT with a median dose of 50.4Gy in 6 weeks. RESULTS: After a median follow-up of 20 months (1-68 months) a 95% (21 of 22) visual control was seen: vision improved in 16 patients and remained stable in 5. For 13/16 patients improvement was documented already within 1-3 months after SCRT. Vision became worse in one patient. An improvement of pain was observed after radiotherapy in 6 patients as well as of proptosis in 1 patient. For 1 patient pain was persistent after SCRT. In one patient 4 years after SCRT a radiation retinitis and vitreous haemorrhage was seen. CONCLUSIONS: Fractionated stereotactic radiotherapy improves vision, often shortly after treatment, and is thus a viable treatment option for this tumour entity.

Adolescent↗