Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “TREMATODE INFECTIONS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 847 records · Page 47Linked to original sources
PubMed1999

Natural mass infection by heterophyid metacercariae in aquacultured Japanese eel in Taiwan.

A natural mass infection of heterophyid metacercariae in aquacultured Japanese eel Anguilla japonica in Taiwan was observed. Of the 28,000 adult eels in 2 ponds, about 25,000 (90%) showed swollen, cloudy and white eyes. Although morbidity was about 90%, there was no mortality among the affected eels. Histopathological sections showed edema and hemorrhage of the eye. Numerous metacercariae were observed in the muscle tissues around the eyeball, the subcutaneous tissue and even in the cartilage. Of the 6 eels digested with artificial gastric juice, all were found to contain metacercariae in their muscle tissues. The average number of metacercariae recovered from the 6 eels was 1219, with a range of 50 to 3762. These metacercariae, when fed orally to immunodeficient (scid) mice, developed into adult worms which were identified as Procerovum cheni Hsu 1950. The naturally infected eels were transferred to a new pond without snails and their eye lesions were not apparent anymore after 2 wk. In a follow-up investigation, 19 of 20 apparently healthy eels in a nearby aquaculture farm were found to harbour metacercariae in their muscles. However, the number of the metacercariae ranged from 1 to 14, with an average of 4.21. This is the first report of heterophyid metacercariae causing mass morbidity in aquacultured eels.

Anguilla↗
PubMed1978

Parasites of red foxes in New Brunswick and Nova Scotia.

Sixty-one red foxes from New Brunswick and Nova Scotia were examined for helminths. Alaria americana, A. arisaemoides, A. mustelae, Cryptocotyle lingua, Echinostoma revolution and Metorchis conjunctus, Capillaria aerophila, Crenosoma vulpis, Toxocara canis, Uncinaria stenocephala and Taenia crassiceps were found. Approximately 67% of the foxes examined were clinically affected with Sarcoptes scabiei mange.

Animals↗
PubMed1975

Shrews: a review of the diseases, anomalies, and parasites.

The diseases, lesions, congenital disorders, and parasites of both Insectivora and prosimian shrews were reviewed. Preliminary baseline data provide encouraging prospects for using these animals as research models because few spontaneous diseases and lesions have been reported. It must be pointed out, however, that throughout the literature reviewed, clinical histories were incomplete and histopathologic examinations had seldom been performed, particularly with the parasitic entities.

Adenocarcinoma↗
PubMedDate not supplied

[Larval Clinostomum infection of cichlid fish in the lake of Kompienga in Burkina Faso: a menace to haleutic exploitation and public health].

Clinostomum sp. is a trematode, a parasitic worm, of which the larva infest a number of species of wild fish. In intertropical Africa and particularly in artificial lakes in the east of Burkina Faso, the infestation is especially observed in the cichlids fish. Because cichlids constitute 80 to 90% of the fish catches, enzootic infestation could infringe upon the fisheries, and also adversely affect public health. For this epidemiological study conducted during the first three quarters of 1994, we examined a total of 932 cichlids, a mix of all species. Prevalence (Pr) and intensity (I, number of parasites per fish) were the two indicators of the infestation level. 387 fish were carriers of the parasite, comprising 41.5% of the total. Differences were observed between the species of cichlids. Oreochromis niloticus was the most infested (Pr, 56%; I, 17), followed by Sarotherodon galilaeus (Pr, 44%; I,6); and Hemichromis fasciatus (Pr, 20%; I, 5). In 89% of the carriers, the parasite was localized on the internal face of the operculum and in the pericardial septum, compared to 11% of the localizations in subcutaneous and muscular tissues. These last two localizations render the fish repugnant, and can cause the fresh fish to be rejected. If the parasitized fish is not rejected and then insufficiently cooked, as occurs at public grills with multitudes of consumers, the living parasite can penetrate and stay in the upper digestive tract and constitute a threat for consumer health.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1997

Genotoxic activity of praziquantel.

Praziquantel is a synthetic drug with a remarkable activity against parasites, particularly treamatodes and cestodes. Initial genotoxicity tests used a spectrum of endpoints including tests in bacteria, yeasts, mammalian cells and Drosophila and each one gave negative results. Effects on reproductive cells of mice were negative as well. However, host mediated studies in mice and humans were contradictory and a comutagenic effect with several mutagens and carcinogens was found. Later studies, including monitoring in humans and pigs have shown that Praziquantel induces a greater frequency of hyperploid lymphocytes as well as structural chromosomal aberrations, but not in all the individuals treated. In vitro studies have demonstrated that Praziquantel can induce micronuclei in syrian hamster embryonic (SHE) cells and in lymphocytes of some individuals. The same was found about structural chromosomal aberrations. Fetal death and fetal resorption were found when Praziquantel was administered in high doses to pregnant rats between the 6th and 10th day of gestation. Due to its efficiency as a parasiticide, Praziquantel is in use in Latin-American, Asiatic, African and East-European countries where infections by trematodes and cestodes are frequent. However, the extensive use of Praziquantel in multiple reinfections, in non-infected and non-diagnosed individuals for prevention, in higher doses or repeated doses for cysticercosis treatment and in individuals exposed to environmental mutagens, in conjunction with new findings about its metabolism and genotoxic properties, make it necessary to further evaluate the potential of this drug not only to be mutagenic per se, but to contribute in the development of neoplasm.

Animals↗
PubMed2000

High-performance thin-layer chromatographic analysis of lutein and beta-carotene in Cerithidia californica (Gastropoda) infected with two species of larval trematodes.

High-performance thin-layer chromatography (HPTLC) analysis was done on lutein and beta-carotene in the digestive gland-gonad complex (DGG) and whole body of uninfected Cerithidia californica snails and those infected with the larval trematodes Mesostephanus appendiculatis or Euhaplorichis californiensis. HPTLC of the DGG extract on C-18 reversed-phase plates developed in petroleum ether-acetonitrile-methanol (1:2:2) mobile phase showed 2 identifiable pigment zones; the least polar zone had a retention factor (Rf) of 0.07, identical to a beta-carotene standard, and the more polar zone had an Rf of 0.41, identical to a lutein standard. Densitometric scanning of the pigment zones in sample versus standard chromatograms showed that the weight percent of lutein in the uninfected DGGs (3.4x10(-3)%) was significantly greater (P<0.05) than that of DGGs infected with either M. appendiculatis (0.35x10(-3)%) or E. californiensis (0.82x10(-3)%). Changes in beta-carotene in the infected DGGs were insignificant compared to the uninfected controls. However, the beta-carotene content of whole snails was significantly reduced (P<0.05) by infection with either trematode.

Animals↗
PubMed1996

Vaccination against worm parasites of animals.

The 1990s have seen the culmination of decades of painstaking research with the registration and launch of Tickgard (Hoechst), a recombinant vaccine against Boophilus microplus, and the provisional registration of a Taenia ovis vaccine. Research continues to hold promise for immunological control of Echinococcus, Fasciola, Haemonchus, Trichostrongylus and Ostertagia. Blood-sucking parasites (e.g. ticks and H. contortus) are susceptible to control by vaccines containing 'novel' or 'concealed' antigens where serum antibodies in blood meals attack targets in the gut. Antibodies also provide protection in taeniid models, whereas the protective response to be sought in Fasciola remains unclear. More problematic are formulations and delivery strategies to induce expulsion of gastrointestinal nematodes, using vaccines containing recombinant 'conventional' antigens. The use of computer models to simulate vaccine efficacy in worm control and challenges to the concept of 'hypo-responsiveness' of young lambs will encourage cautious optimism and lively debate as to the prospects for integrated worm control using parasite vaccines. This review covers the aspirations, current success and problems faced by researchers in the parasite arena.

Animals↗
PubMed1987

Heterophyes species in Greece: record of H. heterophyes, H. aequalis and H. dispar from the first intermediate host, Pirenella conica.

Heterophyes heterophyes is reported for the first time from the snail host Pirenella conica in Greece. H. aequalis and H. dispar are reported for the first time from Greece and from Europe. The results presented, together with the available data on necropsies of dogs and cats, human infections and the biotope preference of the snail, suggest that Greece is an important focus of infection in Europe.

Animals↗
PubMed1991

Studies on the infectivity of Diplostomum spathaceum in rainbow trout (Oncorhynchus mykiss).

The infectivity of Diplostomum spathaceum (Digenea: Trematoda) cercariae to rainbow trout and the efficacy of the diplostomule migration to the lens following different routes of administration was examined. The optimum age of infectivity for cercariae was between 0-5 h after liberation from the snail and for intraperitoneally injected diplostomules, 5 h post-transformation in vitro through fish skin. After exposure of the entire fish body or head to cercariae, metacercariae first appeared in the lens at 5 h and their numbers gradually increased until 22 h. Following exposure of the tail region of rainbow trout to cercariae, metacercariae first appeared in the lens at 14 h. Significantly more metacercariae established in the lens of fish following exposure of the fish head compared with the tail region; 40% of penetrating cercariae reached the lens of fish following exposure of the head or entire body, 20% of cercariae or diplostomules injected either intraperitoneally, intramuscularly or intracardially reached the lens while only 5% of cercariae established as metacercariae following exposure of the tail region.

Animals↗
PubMed2004

Eye fluke-induced cataract formation in fish: quantitative analysis using an ophthalmological microscope.

We examined the parasite-induced cataract formation in rainbow trout (Oncorhynchus mykiss) using slit-lamp microscopy to determine the relationship between cataract intensity and number of Diplostomum spathaceum parasites that were established in the lens. Cataract intensity increased significantly with parasite burden, but was also affected by the pattern of exposure to the parasite cercariae. The slit-lamp methodology proved useful in scoring the cataracts since it provides a 3-dimensional view into the lens and gives an actual picture of the location and intensity of the cataracts, which allows detailed investigations of mechanisms underlying cataract formation in various fish species. Potential applications of the method in fish farming and parasitological studies are discussed.

Animals↗