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At least 847 records · Page 47Linked to original sources
PubMed2006

Endogenous hydrogen sulfide and the cardiovascular system-what's the smell all about?

PURPOSE: Hydrogen Sulfide has been found to be produced endogenously in amounts that cause vasodilatation. The purpose of this review is to outline the effects of hydrogen sulfide as a gasotransmitter. METHODS: This article is a summary of work done in Dr. Rui Wang's laboratory and a comprehensive review of H2S on the Pub-Med website. PRINCIPLE FINDINGS: One of the specific cellular targets of hydrogen sulfide is the K(ATP) channel protein which produces vasodilatation. The other gasotransmitters like NO (nitric oxide) interact with hydrogen sulfide in complex ways. This action could be important in hypertension and other vascular diseases. CONCLUSION: Gasotransmitter research is relevant to the pathophysiology of a number of cardiovascular disease processes.

Animals↗
PubMed1988

Dysfunction of sense of smell caused by canine parainfluenza virus infection in dogs.

Olfactory function of 5 dogs that were naturally infected with canine parainfluenza virus and of 4 dogs that were inoculated with the C958 strain of canine parainfluenza virus was evaluated. Except for one dog that was inoculated, the threshold for detection of benzaldehyde and/or eugenol was found to be excessively high during the course of the disease, as determined by electroencephalographic and behavioral olfactometry. In experimentally infected dogs, an increase in threshold developed in the absence of other clinical signs of disease. Changes were not observed in electro-olfactograms recorded throughout the study. Olfactory thresholds returned to normal after the disappearance of clinical signs of disease in the naturally infected dogs. Necropsies and histologic examinations performed during the course of the disease did not reveal abnormalities of the olfactory mucosa.

Animals↗