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At least 847 records · Page 47Linked to original sources
PubMed2000

Inspiratory effort sensation to added resistive loading in patients with obstructive sleep apnea.

STUDY OBJECTIVES: Repeated episodes of upper-airway occlusion are the main characteristics of patients with obstructive sleep apnea (OSA) during sleep. It has been reported that an impairment in the sensation of detection and a depression of ventilatory compensation to added load could be observed in such patients. In this study, we examined patients with OSA to evaluate the inspiratory effort sensation (IES), ventilation, and mouth occlusion pressures during added resistive loading while awake and to determine whether they can be reversed by nasal continuous positive airway pressure (CPAP) treatment. DESIGN: A hospital-based case-control study. SETTING: A sleep laboratory of a medical unit in Japan. SUBJECTS: Seventeen patients with moderate to severe OSA and 10 control subjects were included in this study. MEASUREMENTS: All patients with OSA had undergone standard nocturnal polysomnography. Patients with OSA and control subjects were evaluated for IES measured by a modified Borg score, ventilation, and mouth occlusion pressure during control and inspiratory resistive loaded breathing. These tests were repeated in all patients with OSA after 2 weeks of nasal CPAP treatment. RESULTS: IES to inspiratory resistive loading was lower in patients with OSA than in control subjects. There were no differences in ventilation and mouth occlusion pressure between patients and control subjects during loaded breathing. After 2 weeks of nasal CPAP, the decreased IES was increased in patients with OSA. CONCLUSION: In patients with OSA, the decreased IES to inspiratory resistive loaded breathing is reversible with nasal CPAP. This could be one additional benefit of nasal CPAP in the treatment of OSA.

Airway Obstruction↗
PubMed1995

A study on the difference of human sensation evaluation to whole-body vibration in sitting and lying postures.

The evaluation of vibration sensation is a problem which has large individual differences. In order to clarify the relationship between posture and psychological response, human sensation to whole-body vibration (from 2 to 11 Hz) in sitting and lying postures was evaluated by the semantic differential method, and the influences of posture on the evaluation were investigated by using the fuzzy measure. Furthermore, the paired t-test was used to test the significant differences in the results of evaluation between the two postures. The results were as follows: (1) Psychological responses of human beings to whole-body vibration were greatly affected by the postures. (2) Changes of the psychological responses in the lying posture were smaller than those in the sitting posture. (3) There were significant differences between sitting and lying postures in the evaluation results of physiological factor, psychological factor and synthetic evaluation (P < 0.025).

Adaptation, Psychological↗
PubMed1992

Fatigue sensation and surface electromyogram during sustained shoulder flexion with spontaneous alternations of working arm.

Sustained contractions were compared between with (AW) and without (NAW) spontaneous alternations of working arm to investigate the fatigue level at which the contraction is felt to be stopped. Subjects maintained an upper limb in the horizontally flexed position at 5%, 10%, 15% and 20% of maximum voluntary contraction strength (MVC). Contractions were continued until they felt exhausted or 45min. had passed. Fatigue level was evaluated with 4 levels of fatigue sensations and surface electromyogram (EMG) of the deltoid. Mean amplitude (AEMG) and relative power in 8-40Hz (RPLF) of EMG were calculated. The following results were obtained. Fatigue level was lower in AW than in NAW for the same amount of work done by one arm. As AEMG often decreased with time, fatigue was estimated by relating AEMG to RPLF. At 20% MVC in AW the alternation interval decreased and the muscle fatigued with repeated contractions though the fatigue level was not severe. Contraction was felt to be stopped when the first fatigue sensation occurred. But it was not necessary to stop the contraction until considerable tiredness or apparent pain occurred.

Adult↗
PubMed1999

Mandibular-position sensation during sedation by administration of nitrous-oxide (N2O) gas.

Our aim was to confirm the influence of N2O gas on mandibular-position sensation. The subjects in this study were eight healthy adults. Each subject was asked to hold the reference stick for five seconds between the central tooth in his or her upper and lower jaws. Then, the reference stick was replaced by the test sticks with different thickness, each of which the subjects were again asked to hold at the same position for five seconds. The subjects were instructed to determine, based on judgement of the interincisal distance, whether the thickness of each test stick was larger or smaller than the reference stick. A series of trials was administered to each subject using all eight sizes of test sticks. We compared the ability of the subjects to discriminate mandibular position both before and after the application of a vibrating stimulus to the masticatory muscles, and before and during the administration of N2O gas. Discrimination ability was significantly decreased after the application of the vibrating stimulus. However, during the administration of N2O gas, no significant difference in discrimination ability was observed between before and after the vibrating stimulus. The results of this study indicated that N2O gas had an inhibitory effect on gamma-motor neuron activity, which is presumed to be mediated to some extent through the higher central nervous system. This is the case because the gamma-motor neurons are generally activated by vibrating stimuli applied to the muscle causing decreased discrimination ability of mandibular position. Thus, we conclude that mandibular-position sensation was influenced by N2O gas during the administration of N2O gas.

Adult↗
PubMed1987

Sensation seeking and estimation of numerosity.

In a sample of 81 subjects, significant negative correlations were obtained between scores on Zuckerman's Sensation Seeking Scale and estimates of numerosity. A cognitive view of sensation seeking was suggested, according to which high scores are a function of an underestimation of the amount of stimulation experienced and low scores a function of overestimation. This approach was discussed in relation to motivational theories and those involving strength of the nervous system.

Adult↗
PubMedDate not supplied

The effect of lignocaine on nasal resistance and nasal sensation of airflow.

The effect of lignocaine on nasal sensation of airflow and nasal resistance was assessed in twenty-five subjects. A randomised crossover trial was conducted with lignocaine as the active drug and saline as the placebo. Both substances were delivered to the nasal mucosa as a nasal spray. Lignocaine caused a sensation of increased nasal patency in twenty-two of the twenty-five subjects studied. Saline had no such effect. The difference between this subjective effect of the two substances was highly significant (p less than 0.001). Neither spray had any significant effect on nasal resistance to airflow assessed objectively by rhinomanometry.

Adult↗
PubMed1990

Spatial features of vibrotactile masking effects on airpuff-elicited sensations in the human hand.

It was recently shown that the cutaneous sensitivity to airpuffs is decreased by a low-frequency vibrotactile masker in the hairy skin, and by a low-frequency but especially by a high-frequency masker in the glabrous skin. In the current study, the spatial features of this masking effect were determined in four healthy human subjects, using a reaction time paradigm. The masking effect decreased monotonically with increasing interstimulus distance, and identically in longitudinal and transverse (i.e., lateral) directions in the palm or dorsal surface of the hand. The masking effect was stronger in the glabrous than in the hairy skin, especially in the fingers. In the glabrous skin, the spread of masking effect produced by a high-frequency masker was more extensive than that produced by a low-frequency masker. The mechanical spread of high-frequency vibration was less extensive than that of low-frequency vibration in the skin. In the glabrous skin, a masker applied to the tip of the finger produced a stronger masking effect on sensations in the base of the finger than when the masker was located at the base and the test stimulus was located at the tip. It is concluded that mechanical spread of vibration in the skin is of minor importance in explaining the masking effects. Different peripheral neural mechanisms underlie the airpuff-elicited sensations in the hairy and glabrous skin. The afferent inhibitory mechanisms are stronger for signals coming from the glabrous skin of the fingers than for signals coming from the hairy skin. Furthermore, the peripheral innervation density and size of the cortical representational areas may be of importance in determining the magnitude of the masking effect.

Adult↗
PubMed1989

[Psychosomatic aspect of a choking lump sensation in the throat].

In order to elucidate the relationship between a choking lump sensation in the throat and psychosomatic status, the authors subjected 339 in-patients above 17 years of age with various kinds of otorhinolaryngologic diseases and evaluated their psychosomatic conditions by means of two questionnaires: Cornell Medical Index Questionnaire (CMI) and Maudsley Personality Inventory (MPI). According to the answer to one of the CMI questions "Do you often feel a choking lump in your throat?", the patients were divided into two groups: "Yes" group and "No" one. "Yes" group comprised 51 males (56.1 +/- 15.6 years old of mean +/- SD age) and 34 females (57.9 +/- 13.9 years old) and "No" group 170 males (57.7 +/- 14.3 years old) and 84 females (47.8 +/- 15.8 years old). The data were analysed for comparison between the two groups and the following results were obtained. Patients with benign and malignant oral, pharyngeal and laryngeal diseases were included in the "Yes" group with a significantly higher rate when compared to the patients with benign and malignant ear or nasal diseases. Patients in "Yes" group made significantly more complaints and judged to be significantly more neurotic and autonomic nerve dysfunctioning than those in "No" group. Therefore, diseases in the pharyngolaryngeal region more likely produces abnormal sensation in the throat as well as many other symptoms relating to the autonomic nerve function.

Adolescent↗
PubMed1989

[An attempt to construct the Sensation Seeking Scale-Abstract Expression].

The purpose of this study is to construct Sensation Seeking Scale-Abstract Expression (SSS-AE), consisting of 15 items. All items were described in relatively abstract terms. Data were collected from Japanese college students (246 males and 121 females). The total SSS-AE scores had positive correlation with the general factor of sensation seeking. This confirms the validity of the SSS-AE proposed in this study. From the factor analysis of the items, three factors were extracted: Thrill and Adventure Seeking (TAS), Disinhibition (Dis), and Experience Seeking (ES). But Boredom Susceptibility (BS) was not confirmed. These results were discussed in comparison with the factors reported by Zuckerman. Males showed higher ES scores than females, but females showed higher Dis scores than males.

Adult↗
PubMed1999

[An attempt to restore protective sensation after a greater omentum flap coverage due to circular soft tissue defect in the hand].

The paper presents method of restoration of protective sensation after major hand injuries primarily treated with great omental flap. Existing methods have been modified on assumption that free end of transplanted sural nerve might act as sensation receptor. Two patients were operated on. Several months after surgery patients reported paresthesiae at skin compression. Function improvement is seemingly indicated by objects less frequently falling of out of the hand.

Hand↗
PubMed1997

[The effects of menthol, borneolum and moschus on nasal airflow sensation and nasal resistance].

Menthol and borneolum have been used widely in traditional Chinese medicine for the treatment of nasal obstruction, but the mechanism has been still unknown. The effects of inhalation of menthol, borneolum, moschus on nasal resistance and airflow sensation were investigated in 52 subjects. All of these medicines could cause a highly significant enhancement of nasal airflow sensation but had no effect on nasal resistance. Therefore this sort of medicine is regarded as pseudo nasal decongestant.

Adult↗
PubMed2000

Perception of surrounding space controls posture, gaze, and sensation during Coriolis stimulation.

BACKGROUND: Motion sickness evokes not only discomfort but also marked equilibrium ataxia. However, its mechanism of ataxia remains unclear. HYPOTHESIS: We supposed that stance, gaze, and sensation may be uniformly controlled by the perception of the surrounding space. METHODS: Using Coriolis stimulation, we examined eight normal subjects and two patients with bilateral labyrinthine loss. They were asked to stand on a platform; then while being rotated clockwise 60 degrees x s(-1), they tilted their head 30 degrees. Displacement of the center of pressure and ocular movements were recorded using a force platform set on the device and an infrared CCD-video camera fixed to goggles, respectively. RESULTS: In normal subjects with eyes covered, tilting of the head resulted in shifts of the center of pressure and torsional or vertical nystagmus. When they could see the surroundings, they showed stable posture and optokinetic nystagmus regardless of head tilting status. In contrast, the two patients were not affected by head tilting when their eyes were covered, although they showed remarkable body swaying even while they were static. CONCLUSIONS: From the present study, it seems probable that posture, gaze, and sensation are absolutely controlled by the perception of surrounding space, which may be theoretically represented as a vector in the head.

Adult↗
PubMed2002

Prevention of phantom sensations after spinal anesthesia.

BACKGROUND AND OBJECTIVES: Phantom limb sensation (PLS) after the spinal anesthesia is an unpleasant experience. The occurrence rate was 80 to 83 per cent from previous studies. The purpose of this study is to evaluate the incidence of PLS, comparing between placing the lower limbs in the neutral position when analgesic level reach L1 dermatome (L1 group) and T6 dermatome (T6 group). METHODS: Ninety ASA physical status I-II patients, 19-50 year of age, scheduled for lower abdominal surgery under spinal anesthesia were enrolled. Immediately after the spinal injection, the patients were placed supine with one of lower limbs flexed (both hip and knee) and the other kept straight in the neutral position. The analgesic levels were checked every minute; the flexed limbs were turned to the neutral position when the analgesic level reached L1 and T6, the L1 group and the T6 group respectively. The images of the lower limbs and patients' satisfactions were evaluated 15 minutes after the blockage. RESULTS: Twenty per cent of the patients in the L1 group experienced PLS of the flexed limbs while 82.2 per cent of the patients in the T6 group did (P<0.05). None of the patients in the L1 group felt unsatisfied with PLS, on the other hand, 11.1 per cent of the patients in the T6 group expressed their dissatisfaction and would like to have their limbs extended. CONCLUSIONS: This study revealed that by placing the lower limbs in the neutral position immediately after the spinal injection, before the unwanted positions are memorized, could effectively minimize phantom limb sensation after spinal anesthesia.

Adult↗
PubMed1975

[Construction of a finger substitute with sensation following the loss of all fingers].

On a patient with traumatic loss of all of the fingers a light but satisfactory grip was obtained by the construction of an opposition post with sensation. This was achieved by a tubed abdominal pedicle flap containing iliac bone graft. A neurovascular cross-finger flap was transfered from the uninjured hand in such a way that an anastomosis to a branch of the nerve of the injured hand was possible, allowing for the development a satisfactory sensation.

Abdominal Muscles↗
PubMed1992

[Is the lower urinary tract sensation different in patients with bladder instability?].

The author examined the sensory innervation of the lower urinary tract in two ways: by evaluation perception of bladder fullness and by determining the perception threshold to electrical stimulation of the urethral and bladder wall. The results obtained in 95 patients with detrusor instability were compared to those of 312 patients with no neurological disease and a stable detrusor. Patients with detrusor instability reported sensations of fullness at statistically significantly lower volumes than patients with a stable detrusor. In contrast, the threshold of perception of electrical stimulation was the same in the two groups, which indicates that the sensory system involved in the perception of electrical stimulation is independent of motor function, while the sensation of fullness is influenced by detrusor motor activity. These results constitute additional evidence that perception of fullness and perception of electrical stimulation are related to two different pathways of afferent innervation.

Adolescent↗
PubMed1992

Nasal airway resistance and nasal sensation of airflow.

Nasal obstruction is a common symptom which is most frequently associated with an increased nasal airway resistance. However it is important to appreciate that the objective measurement of nasal airway resistance does not always correlate with the subjective perception of the degree of nasal obstruction. Damage to trigeminal sensory nerve endings can cause a sensation of nasal stuffiness without any change in nasal airway resistance and similarly inhalation of menthol can cause a subjective improvement in nasal sensation of airflow without any change in nasal resistance.

Airway Resistance↗
PubMed2003

[Penis reconstruction with sensation and erectile function maintained (report of 40 cases)].

OBJECTIVE: To reconstruct a penis with sensation and erectile function maintained by corpora cavernosa lengthening and skin flap transferring in the penis defect cases. METHODS: The procedure was based on the use of releasing the suspensory ligaments and part of crus, various flaps were designed as coverage material. Penis residual stump was advanced to anterior portion of the newly reconstruction penile body as "glans". RESULTS: 40 patients with penis defect have been operated by the above methods. In the cases, length of the penis varied from 0.5-4.0 cm in the flaccid, 1.5-5.0 cm in erect state before operation. And after operation, it turned to 5.0-8.5 cm in the flaccid, 7.0-12.5 cm in erect state. Most of the patients recovered gross tactile sensation and had satisfactory erectile function. CONCLUSION: With this method, the reconstructed penis tends to have a better appearance and function. It's a more optimal method compared with the conventional operation.

Adult↗