Congenital transverse facial cleft.
Explore the source record for details and available documents.
SEARCH · Search PubMed
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
This paper presents the results and analysis of the distribution frequencies of orofacial features in a population and among the relatives of 325 probands with cleft lip and palate. Our results indicate that some of the features (diastema, nostril asymmetry and others) are more frequent in the relatives of children with clefting than in a general population. These studies suggest that several minor clinical conditions in parents may be important for medico-genetical consultations.
Possibilities are indicated of early functional orthodontic treatment in babies and small children with Down's Syndrome with orofacial pathology.
Attention is directed towards the use of new techniques in cytogenetics. C-, G-, Q-, and R-banding methods are briefly discussed and illustrated. Methods of sister chromatid differential staining and silver staining for demonstration of nucleolus organizing regions are reviewed and their application in medical cytogenetics is pointed out. Frequency of chromosomal aberration and the importance of the orofacial area in diagnosis of chromosomal syndromes are the bases for the argument for the usefulness of cytogenetics in the field of stomatology-dentistry.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The growth and fusion of facial processes were studied in White Leghorn chicken embryos treated with hydrocortisone. This treatment results in complete bilateral cleft beak in 80-100% of cases. The frontonasal complex of the experimental embryos exhibited marked hypoplasia prior to cleft manifestation. During the critical period for cleft beak formation, the maximum mitotic activity was concentrated in the medial nasal processes, which thus became vulnerable to the mitosis inhibiting effect of corticoids. Primary hypoplasia of the facial processes was documented as a causative factor of corticoid-induced cleft beak which is analogous to mammalian cleft lip/palate.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.