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[Symptoms reported by mobile cellular telephone users].

A survey study, using questionnaire, was conducted in 161 students and workers in a French engineering school on symptoms experienced during use of digital cellular phones. A significant increase in concentration difficulty (p < 0.05) was reported by users of 1800-MHz (DCS) cellular phones compared to 900-MHz (GSM) phone users. In users of cellular phones, women significantly (p < 0.05) complained more often of sleep disturbance than men. This sex difference for sleep complaint is not observed between women and men non-users of cellular phone. The use of both cellular phones and VDT significantly (p < 0.05) increased concentration difficulty. Digital cellular phone users also significantly (p < 0.05) more often complained of discomfort, warmth, and picking on the ear during phone conversation in relation with calling duration per day and number of calls per day. The complaint of warmth on the ear might be a signal to users for stopping the call.

Academies and Institutes↗

[Video screen exposure and 6-sulfatoxymelatonin urinary excretion in women].

A study in blind conditions was conducted on 13 women (mean age < 30 years). Six women worked at least four hours per day, five days a week, since more than one month, in front of a video screen constituted the exposed group. Radioimmunoassay of 6-sulfatoxymelatonin was done on urine collected during night. Results were analysed by a non parametric rank-test (Mann-Withney). It was observed an important (- 54%) and significant lower level (p < 0.01) of 6-sulfatoxymelatonin in urine of women exposed to video screen.

Adult↗

The evolution of display technologies in PACS applications.

Picture archiving and communications systems (PACS) systems have been around for over a decade now. The most visible components in a PACS system are the PACS workstations. Most of the clinical users of PACS only interact with the display hardware/software pieces and never truly think about the archival and communications that occur behind the scenes. This paper discusses the evolution of PACS display technology in the past 16 yr, which can roughly be divided into three phases and will also discuss future emerging trends.

Computer Terminals↗

Pulmonary nodule detection and visual search: P45 and P104 monochrome versus color monitor displays.

RATIONALE AND OBJECTIVES: The faceplate of a cathode-ray tube (CRT) display monitor is covered on the vacuum side with a phosphor screen. The different phosphors that can be used for this screen have distinctly different physical properties that can affect the noise properties of the display. Differences in noise affect the signal-to-noise ratio and, hence, may affect diagnostic performance. This study evaluated observer performance and visual search parameters in the detection of pulmonary nodules, comparing two monochrome CRT monitors with different phosphors (P45 and P104) and a color CRT monitor. MATERIALS AND METHODS: The receiver operating characteristic paradigm was used to evaluate observer performance with a series of radiographic chest images containing solitary pulmonary nodules. Eye position was recorded as the observers searched the images on each type of monitor. RESULTS: Observer performance, as indicated by the area under the receiver operating characteristic curve and compared by means of an analysis of variance test, was best for the P45 monitor, next best for the P104 monitor, and worst for the color monitor. All differences were statistically significant. Eye-position parameters were also affected by monitor type. The time required to fixate the lesion and overall search times were longest with the color monitor. CONCLUSION: The type of phosphor used in the CRT monitor faceplate can affect diagnostic performance and visual search parameters. Care should be taken in the selection of monitors for use in clinical radiology.

Analysis of Variance↗

Adaptive local contrast enhancement method for medical images displayed on a video monitor.

It is known that light-box luminance is an important factor in the detection of objects on radiographs. Existing methods for image contrast enhancement do not consider the luminance effect so that the enhancement may be inappropriate for the processed image displayed on a video monitor. Based on the properties of human visual system (HVS), an adaptive local contrast enhancement (ALCE) method was developed to enhance the medical image displayed on the video monitor by investigating the influence on human eyes of display luminance difference between a conventional light-box and a video monitor. The HVS model indicated parts of a radiograph unclear to human eyes at a given display luminance. By calculating the contrast of the image pixel by pixel, we found the parts of an image that are needed to be amplified at low display luminance and provided these parts with adequate enhancement. The processed image displayed on a video monitor was visually equivalent to the raw radiograph displayed on a light-box. A quantitative evaluation method of image quality assessment was used to compare the ALCE-processed image with others.

Biophysical Phenomena↗

Communication technologies in health care environments.

A successful implementation of hierarchical health care networks is dependent on a number of different technical and non technical factors. This paper investigates how the networking technologies, both 'traditional' and broadband, can support the communication requirements of medical environments. The general purpose is to implement communication infrastructures and services, which will improve the collaboration between the different partners in the health sector in offering better healthcare services at affordable costs.

Computer Communication Networks↗

A comprehensive software suite for the analysis of cDNAs.

We have developed a comprehensive software suite for bioinformatics research of cDNAs; it is aimed at rapid characterization of the features of genes and the proteins they code. Methods implemented include the detection of translation initiation and termination signals, statistical analysis of codon usage, comparative study of amino acid composition, comparative modeling of the structures of product proteins, prediction of alternative splice forms, and metabolic pathway reconstruction.

Alternative Splicing↗

Recycling of scrap cathode ray tubes.

It is estimated that approximately 50% of the weight of a computer monitor is composed of cathode ray tube (CRT) glass. Thus, the successful recycling of scrap CRT glass can greatly relieve the disposal problem created by scrap monitors. CRT glass may be considered a hazardous waste due to its high lead concentration. A CRT can be divided into panel (front) glass and funnel (back) glass. Several coatings have been applied to the surface of the CRT panel and funnel glass. These coatings may present an adverse effectto the environment by obstructing the recycling and reuse of the CRT glass. To recycle CRT glass, a series of tests has been conducted to remove the coatings from scrap CRT glass. In this study, the CRT panel and funnel glass obtained from scrap computer monitors was cleaned by wet-scrubbing and ultrasonic cleaning methods. This cleaned CRT glass is intended to be recycled and reused by CRT manufacturers. This study shows that the wet-scrubbing method has a better coating removal performance and no associated pollution problem (i.e., no additional chemical additives). Thus, the wet-scrubbing method is recommended for use as a CRT coating removal method. The results of these tests are presented in this paper.

Beta Particles↗

Patients' experiences using a computerized program with a touch-sensitive video monitor for the assessment of health-related quality of life.

This study assessed patients' experiences using a computerized program with a touch-sensitive video monitor (TSVM) for the assessment of health-related quality of life (HRQoL). A software program was developed for a computerized form of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, the QLQ-C30. One hundred and seventy-eight patients completed the QLQ-C30, followed by a structured interview designed to assess perceived difficulties with the use of the TSVM. Patients were asked to evaluate the ease of use of different aspects of the TSVM system (using the touch-sensitive screen, entering the patient identification number, reading the screen and following the on-screen instructions). The majority of patients found all aspects of the TSVM system 'very easy' to use. A few patients (1-2%) admitted finding any aspect of the TSVM use 'somewhat difficult' and none ranked any aspect as 'very difficult'. There were no unanswered items in the QLQ-C30. All patients found the amount of time spent on answering the questionnaire acceptable, (the mean time to complete was 6.8 min with a median of 5 min) and 96% stated they were willing to complete a similar questionnaire on a future occasion. From the patients' perspective the TSVM system appears to be a highly acceptable approach for the collection of HRQoL data in clinical practice.

Aged↗

Effectiveness of arm supports during typing for adults with neurological disorders.

Four computer-typing accommodations were evaluated to determine if arm supports would enhance typing performance and/or comfort of adults with neurological disorders. Each of 12 adults (6 females and 6 males) participated in 7-min typing tasks under the following conditions: 1) without arm support, 2) Ergo Rest arm support, 3) custom arm support in fixed mode, and 4) custom arm support with movable mode. The objective dependent variables were speed, errors, and type of errors. The subjective dependent measures were reported body part discomfort, and arm support ratings. The data were found to be nonparametric in nature. Therefore, nonparametric techniques were employed to analyze the data. Only one of the objective dependent measures were statistically significant; Type of error (additional key). This result may be attributed to the wide range of disability manifestations among participants. Subjective dependent measures were found to be statistically significant, leading to the conclusion that typing with an arm support was more comfortable and easier than without an arm support.

Adult↗

Muscle learning therapy--efficacy of a biofeedback based protocol in treating work-related upper extremity disorders.

Work-related upper extremity disorders (WRUEDs) continue to present significant treatment and financial challenges to providers, employers, and insurers. This retrospective study reviews outcomes for 309 subjects who, between 1995 and 1999, were referred through the workers' compensation system for treatment of computer keyboard- and mouse-related WRUED injuries. The mean length of time from the recorded date of injury to the date of intake was 12.9 months. Subjects were offered a 12-visit course in muscle learning therapy (MLT). MLT is an operant conditioning program which uses surface electromyography (sEMG) to train injured workers to control their muscles during work activities. Patient response to therapy was obtained by a therapist-administered questionnaire during Visit 8 of 12. A group of 309 subjects, who had failed to respond to a previous course of therapy (typically physical therapy), reported significant improvements of pain in the neck, thorax, and upper extremities. Ninety six percent reported that they felt "more in control," 86% reported feeling "better overall," and 81% reported either "working the same and feeling better" or "working and accomplishing more." This study provides preliminary support for this approach and provides justification for controlled clinical trials in the future.

Adult↗

Understanding work-related upper extremity disorders: clinical findings in 485 computer users, musicians, and others.

Four hundred eighty five patients whose chief complaints were work related pain and other symptoms received a comprehensive upper-body clinical evaluation to determine the extent of their illness. The group had a mean age of 38.5 years. Sixty-three percent of patients were females. Seventy percent were computer users, 28% were musicians, and 2% were others engaged in repetitive work. The time between the onset of symptoms and our initial visit ranged from 2 weeks to over 17 years. A majority sought care within 30 months with the greatest number of them seeking care before 12 months. Fifty nine percent of subjects were still working when seen despite increasing pain and symptoms such as weakness, numbness, tingling, and stiffness. Following a history, a physical assessment utilizing commonly employed clinical tests were performed including evaluation of joint range of motion, hyperlaxity, muscle tenderness, pain, strength, and imbalance. Neurologic tests included Tinel's sign performed in wrist, elbow, tricipital sulcus, and neck and tests for thoracic out syndrome (TOS). Specific tests such as Finkelstein's test for deQuervain's tenosynovitis, Phalen's test for carpal tunnel syndrome and grip strengths were included in the examination protocol. Significant findings included postural misalignment with protracted shoulders (78%), head forward position (71%), neurogenic TOS (70%), cervical radiculopathy (0.03%), evidence of sympathetic dysfunction (20%), and complex regional pain syndrome (RSD) (0.6%). Hyperlaxity of fingers and elbows was found in over 50%, carpal tunnel syndrome in 8%, radial tunnel syndrome in 7%, cubital tunnel in 64%, shoulder impingement in 13%, medial epicondylitis in 60%, lateral epicondylitis in 33%, and peripheral muscle weakness in 70%. We conclude that despite initial presentation distally, work-related upper-extremity disorders are a diffuse neuromuscular illness with significant proximal upper-body findings that affect distal function. While neurogenic TOS remains a controversial diagnosis, the substantial number of patients with positive clinical findings in this study lends weight to the concept that posture related neurogenic TOS is a key factor in the cascading series of physical events that characterize this illness. A comprehensive upper-body examination produces findings that cannot be obtained through laboratory tests and surveys alone and lays the ground work for generating hypotheses about the etiology of work related upper-extremity disorders that can be tested in controlled investigations.

Adolescent↗

Effective medical examination of VDT workers using a new testing method of ocular alignment.

To investigate the relationship between asthenopia of VDT workers and the ocular alignment, we measured far and near alignment of 407 subjects (74 VDT workers with asthenopia, 137 VDT workers without asthenopia, and 196 non-VDT workers) using Total Vision tester (VT-500). There was no relationship between the asthenopia and the records of far alignment test. On the other hand, the incidence of exophoria and convergence insufficiency type in near alignment test was significantly high in the group of VDT workers with asthenopia. From these results, we speculate that cases who have exophoria or show incomplete fusional response measured under the near testing distance (50 cm) tend to complain of asthenopia.

Adaptation, Physiological↗

Bioinformatic analysis of the link between gene composition and expressivity in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

The compositional non-randomness was studied in genes of Saccharomyces cerevisiae and Schizosaccharomyces pombe. In both species, codon usage is well correlated with expressivity (measured as the codon adaptation index). Both species generally display higher nucleotide non-randomness in the group of highly expressed genes than in the lowly expressed genes. The highly expressed genes in both species are furthermore characterized by marked peaks in non-randomness at N=3 upstream of start codons, N=2 downstream of start codons and at N=1 and N=7 downstream of stop codons, indicating that these nucleotides may be key elements in translational regulation. Intragenic variation in codon usage was also observed to be linked to expressivity. It is suggested that the firm link between expressivity and codon usage calls for codon optimization. Based on bioinformatic calculations, examples of proteins are given for which codon optimizations might be relevant.

Base Sequence↗

Young children can extend motion verbs to point-light displays.

In the first study using point-light displays (lights corresponding to the joints of the human body) to examine children's understanding of verbs, 3-year-olds were tested to see if they could perceive familiar actions that corresponded to motion verbs (e.g., walking). Experiment 1 showed that children could extend familiar motion verbs (e.g., walking and dancing) to videotaped point-light actions shown in the intermodal preferential looking paradigm. Children watched the action that matched the requested verb significantly more than they watched the action that did not match the verb. In Experiment 2, the findings of Experiment 1 were validated by having children spontaneously produce verbs for these actions. The use of point-light displays may illuminate the factors that contribute to verb learning.

Child, Preschool↗