Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CANADA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 847 records · Page 47Linked to original sources
PubMed1999

Disability terminology in the media: a comparison of newspaper reports in Canada and Israel.

The terminology used to refer to persons with disability may both reflect and influence attitudes towards them. Negative references may perpetuate negative attitudes and stereotypes. This is of particular importance in the mass media which reaches a broad spectrum of the population. This study looked at disability terminology used in major newspapers in Canada and Israel. It focused on the nature of that terminology and whether its use was related to other factors, such as the disability model reflected in the article, the content of the article (e.g. attributes of the disabled person) and its context (e.g. type of newspaper, feature versus news items). Overall, the use of inappropriate terminology of varying types was quite prevalent in both countries. In addition, in Canada there were a considerable number of articles which had no direct reference to the disability. In general, the terminology used was considerably more positive in articles dealing with individual persons with disabilities (as opposed to groups), with disabled children and with problems of mobility and rights. The results of the study indicate that the choice of terminology cannot be explained by journalistic expedience and conciseness alone.

Attitude to Health↗
PubMed2000

Prevalence and genotypic characterisation of Giardia in dairy calves from Western Australia and Western Canada.

In this study, the prevalence of Giardia duodenalis infections was determined in Western Canadian and Western Australian dairy calves. Faecal samples were collected from Holstein calves located on a commercial dairy near Lethbridge, Alta., Canada (N=28) and from calves located on two commercial dairies located near Perth, WA, Australia (N=36). Faecal samples were examined for the presence of Giardia cysts using sucrose gradient centrifugation, followed by immunofluoresence microscopy. DNA was then extracted from Giardia isolates obtained from positive samples. A PCR based method was employed to amplify and sequence a 292bp region of the 16S-rRNA gene. Genetic sequences obtained from Giardia isolates were compared to each other and to previously sequenced isolates. Following a single faecal sample, 58% of Western Australian calves and 57% of Western Canadian calves were positive for Giardia. Geometric mean cyst counts/g of faeces were 839 for Western Australian calves and 3475 for Western Canadian calves, but these values did not differ significantly. Genetic sequences were obtained from 10 calves from Western Canada, while six sequences were obtained from Western Australian calves. Of the Western Canadian isolates, eight aligned with the proposed 'Hoofed livestock' genotype. Of the five isolates obtained from Western Australian calves, four sequences were identical to the 'Hoofed livestock' genotype. Two isolates from the Western Canadian calves and one isolate from the Western Australian calves had the identical genetic sequence to the Genotype (Assemblage) A sequence, a common human genotype. The results of this study demonstrate, for the first time, that Giardia infections occur in Western Australian calves. Also, calves from different geographical locations appear to be primarily infected with a Giardia genotype unique to hoofed livestock. However, calves can shed Giardia cysts potentially infective for humans. Thus, Giardia infections should be considered important to Australian dairy producers, and infections in calves may pose a risk to public health regardless of geographical location.

Animals↗
PubMed2000

Radiation treatment for cervical esophagus: patterns of practice study in Canada, 1996.

PURPOSE: To assess the patterns of practice among Canadian radiation oncologists who treat esophageal cancers, using a trans-Canada survey, completed at the end of 1996. METHODS AND MATERIALS: One of 3 case presentations of different stages of cervical esophageal cancer was randomly assigned and sent to participating radiation oncologists by mail. Respondents were asked to fill in questionnaires regarding treatment techniques and to outline target volumes for the boost phase of radiotherapy. Radiation oncologists from 26 of 27 (96%) of all Canadian centers participated. RESULTS: High-energy X-rays (>/= 10 MV) were employed by 68% of the respondents in part of the treatment course. The majority (83%) of the radiation oncologists used at least two phases of treatment. Very few, 10 of 59 (17%), responses started with multifield treatment. The most frequently used prescription dose was 60 Gy/30 fractions/6 weeks, given with concurrent chemotherapy. Dose prescriptions were to the isocenter in 39 of 48 (81%) or to a particular isodose line in 9 of 48 (19%) of respondents. CONCLUSION: There was a variety of radiation treatment techniques in this trans-Canada survey. The majority of the patients had combined cisplatin-based chemoradiation. The isocenter was not used consistently as a dose prescription point.

Aged↗
PubMed2000

Biogerontological research in Canada.

There is an ever increasing interest in the study of the aging process. This review is aimed to make an overview of the biological aging research in Canada. I will summarize, to the best of my knowledge, the biological aging research undertaken actually in Canadian institutions dealing with various aspects of this research using many different experimental approaches, models from animals to humans and a huge array of techniques. The biological aging research is developing continuously in Canada, however, it is very important that we assist in a near future to its huge explosion if we would respond to the needs of an ever increasing aging population. Initiatives recently proposed by the Canadian government concerning the creation of Canadian Institutes on Health Research will provide good opportunities to establish a performant, cost-effective, and innovative biological aging research.

Academies and Institutes↗
PubMed1999

Bacterial pathogens isolated from patients with skin and soft tissue infections: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997). SENTRY Study Group (North America).

As part of the SENTRY Antimicrobial Surveillance Program, 1562 bacterial isolates were recovered from hospitalized patients with skin and soft tissue infections (SSTIs) in 30 United States (U.S.) and 8 Canadian medical centers between October and December, 1997. The overall rank order of recovery of the six most common pathogens was Staphylococcus aureus (42.6%) > Pseudomonas aeruginosa (11.3%) > Enterococcus spp. (8.1%) > Escherichia coli (7.2%) > Enterobacter spp. (5.2%) > beta-hemolytic streptocci (5.1%). With one exception, essentially the same order was observed in both the U.S. and Canada. The single exception was the Enterococcus group, which were the third most common isolate in the U.S. (9.6%), but the seventh most common isolate in Canada (3.7). Of note, 24.0% of S. aureus isolates were oxacillin resistant; vancomycin was uniformly active. Vancomycin resistance among Enterococcus spp. (16.5%) was observed only in the U.S. Several antimicrobial agents remained broadly active for SSTI isolates of P. aeruginosa, including meropenem, amikacin, tobramycin, and piperacillin with or without tazobactam. Imipenem resistance (MICs, > or = 8 micrograms/mL) was observed in 11.9% of isolates of P. aeruginosa and ceftazidime, and cefepime had equivalent activity (85.2% and 85.8% susceptible, respectively). Numerous beta-lactams, aminoglycosides and fluoroquinolones were broadly active against E. coli SSTI isolates (i.e. < 5% resistance). Extended-spectrum beta-lactamase production was uncommon both with E. coli and Klebsiella spp. in both nations. Cefepime, imipenem, and meropenem; the aminoglycosides; and fluoroquinolones were conspicuously more active against Enterobacter spp. than other agents tested. High-level, stably derepressed Amp C beta-lactamase production was commonly observed in this group (26.8%), but cefepime generally retained activity against these ceftazidime-resistant organisms. The results of this study serve to define the most common bacterial causes of SSTIs in North America, elucidate patterns of antimicrobial resistance and can be used as a basis for making initial empiric antimicrobial management decisions in hospitalized patients with such infections.

Anti-Bacterial Agents↗
PubMed1998

Antimicrobial activity of quinupristin-dalfopristin (RP 59500, Synercid) tested against over 28,000 recent clinical isolates from 200 medical centers in the United States and Canada.

A total of 200 medical center laboratories in the USA and Canada contributed results of testing quinupristin-dalfopristin, a streptogramin combination (formerly RP 59500 or Synercid), against 28,029 Gram-positive cocci. Standardized tests [disk diffusion, broth microdilution, Etest (AB BIODISK, Solna, Sweden)] were utilized and validated by concurrent quality control tests. Remarkable agreement was obtained between test method results for characterizing the collection by the important emerging resistances: 1) oxacillin resistance among Staphylococcus aureus (41.0 to 43.7%); 2) vancomycin resistance among Enterococcus faecium (50.0 to 52.0%); and 3) the penicillin nonsusceptible rate for pneumococci (31.1% overall, with 10.6% at MICs of > or = 2 micrograms/mL). The quinupristin-dalfopristin MIC90 for oxacillin-susceptible and -resistant S. aureus was 0.5 microgram/mL and 1 microgram/mL, respectively. The quinupristin-dalfopristin MIC90 for vancomycin-resistant E. faecium was 1 microgram/mL, and only 0.2% of isolates were resistant. Other Enterococcus species were generally not susceptible to the streptogramin combination but were usually inhibited by ampicillin (86 to 97% susceptible; MIC50, 1.0 microgram/mL) or vancomycin (86 to 95%; MIC50, 1.0 microgram/mL). Among all tested enterococci, the rate of vancomycin resistance was 16.2%. The quinupristin-dalfopristin MIC90 (0.75 microgram/mL) for 4,626 tested Streptococcus pneumoniae strains was not influenced by the penicillin or macrolide susceptibility patterns. When five regions in the USA and Canada were analyzed for significant streptogramin and other antimicrobial spectrum differences, only the Farwest region had lower numbers of streptogramin-susceptible E. faecium. Canadian strains were generally more susceptible to all drugs except chloramphenicol and doxycycline when tested against E. faecalis (73% and 89% susceptible, respectively). The U.S. Southeast region had S. pneumoniae strains less susceptible to macrolides (73%) but had more susceptibility among E. faecium isolates tested against vancomycin and ampicillin. The Northeast region of the USA had the greatest rate of vancomycin resistance among enterococci. Strains retested by the monitor because of quinupristin-dalfopristin resistance (MICs, > or = 4 micrograms/mL) were generally not confirmed (2.2% validation), and only 0.2% of E. faecium isolates were identified as truly resistant. The most common errors were: 1) species misidentification (28.0%); 2) incorrect susceptibility results (65.6%); and 3) mixed cultures (4.3%) tested by participants. Overall, quinupristin-dalfopristin was consistently active (> or = 90% susceptible) against major Gram-positive pathogens in North America, regardless of resistance patterns to other drug classes and geographic location of their isolation.

Academic Medical Centers↗
PubMed2003

Waiting times, revascularization modality, and outcomes after acute myocardial infarction at hospitals with and without on-site revascularization facilities in Canada.

OBJECTIVES: This study was designed to determine whether admission to a Canadian hospital with on-site revascularization (invasive hospital) affected revascularization choice, timing, and outcome compared with community (non-invasive) hospitals. BACKGROUND: Health care systems in Canada are characterized by relative restraint in diffusion of tertiary cardiovascular services, with capacity for revascularization procedures concentrated in large regional referral centers. METHODS: We used linked administrative data and a clinical registry to follow-up 15,166 Ontario patients who underwent revascularization within the year after their index acute myocardial infarction (MI). Outcomes included recurrent urgent cardiac hospitalization, hospital bed-days, and death within the same year after the index admission. We adjusted for age, gender, socioeconomic status, illness severity, attending physician specialty, and academic hospital affiliation. RESULTS: After adjusting for baseline factors, patients admitted to invasive hospitals were more likely to receive angioplasty than bypass surgery (adjusted odd ratio: 1.85; 95% confidence interval: 1.68 to 2.04, p < 0.001). The converse pattern was seen for patients admitted to community hospitals. Median revascularization waiting times were significantly shorter at invasive hospitals (12 vs. 48 days, p < 0.001). Patients admitted to invasive hospitals had fewer cardiac re-admissions (41.5 vs. 68.9 events per 100 patients, p < 0.001) before their first revascularization and consumed fewer hospital bed-days (379 vs. 517 per 100 patients, p < 0.001). There were no differences in outcomes beyond revascularization. CONCLUSIONS: Outcome advantages associated with timely post-MI revascularization highlight the importance of organizing revascularization referral networks and facilitating access to revascularization for patients with acute coronary syndromes admitted to community hospitals in Canada.

Canada↗
PubMed2003

Romanow, Kirby and Courchene: Canada's health system--a moral or a business enterprise?

This paper examines Thomas Courchene's argument that Senator Kirby was closer to the truth than Commissioner Romanow when Kirby argued that Canada's healthcare system is only sustainable though introducing more private investment. The paper finds that Romanow's position, and indeed the nature of Canada's healthcare system, have been misrepresented by those seeking a larger private market share. The paper concludes the balance of evidence supports Ramanow, not Kirby.

Canada↗
PubMed2002

Towards 2020 strategic triad partnerships in ICT and healthcare: bridging the chasms in Canada and the European Union.

This study examines the management challenges and practices of partnerships between the information and communication technology and healthcare sectors through interviews with selected executives of ICT and healthcare organizations in Canada, Germany, Sweden and the United Kingdom. Underscoring the implications for current and future healthcare executives in Canada, the article also takes a glimpse of the world of strategic partnerships management between these two sectors in the year 2020.

Canada↗
PubMed1999

Is there room for managed care in Canada? A preliminary inquiry of physicians.

Managed care, which is becoming increasingly prevalent in the United States, is virtually absent in Canada. Yet managed care, if implemented judiciously, has the potential to provide comprehensive, high quality care while containing spiraling healthcare expenditures. Managed care is also the foundation of integrated health systems, which have been widely discussed during the past few years. Then why has Canada been so slow to accept managed care? Since physicians have a great deal of influence on how healthcare is ultimately delivered, a group of Ontario physicians was surveyed to determine their perceptions of managed care. It was found that physicians were knowledgeable about the cost-containment capabilities of managed care but had misperceptions about managed care with respect to quality of patient care, preventive services and necessary medical care. Education and further research are recommended so that any debate about managed care, integrated systems or alternative physician payment can be meaningful, objective, beneficial and accurate.

Attitude of Health Personnel↗
PubMed1993

Toward national health system guidelines in Canada: reflections of a comprehensive audit.

A comprehensive assessment of the Health Program Guidelines (HPG) in Canada was undertaken between January and September 1992. This review examined the strategic effectiveness and operational efficiency of the guidelines under the auspices of the Federal, Provincial and Territorial Committee on Institutional and Medical Services. To assess the perceived needs for the guidelines, over 185 structured mail questionnaires were sent to a sample of health care agencies, institutions and organizations across Canada; the response rate was over 80.5%. A key informant approach was also used to assess the perceived effectiveness and efficiency of the guidelines. Based on the results of the questionnaires, over 45 interviews and an extensive content analysis of key documents, recommendations were made that may be relevant to the Canadian health system community.

Canada↗
PubMed1988

The low cost of universal access to healthcare in Canada.

The significant difference between Canada and the United States in respective share of productive activity consumed by healthcare has emerged only since 1971. This difference, currently about 2.5 percent of GNP, is concentrated in three components--medical care, hospital care and administration. Highlighted are the Canada-U.S. dissimilarities, both in overall healthcare cost and experiences since 1971. The reasons are tracked to greater U.S. hospital daily servicing intensity, higher U.S. physician fees, and the cost of the fragmented public-private U.S. system of administration and regulation.

Canada↗
PubMed1999

In vitro activity of several antimicrobial agents against 1003 isolates of Streptococcus pyogenes collected from Western Canada.

Streptococcus pyogenes is a common pathogen which may be associated with significant morbidity and mortality. Recent information is not readily available, in Canada, regarding the susceptibility of clinical isolates to penicillin, extended spectrum and/or newer agents. We collected and tested 1003 isolates of S. pyogenes to seven antimicrobial agents and found the following susceptibility rates: azithromycin 97%, ceftriaxone 100%, ciprofloxacin 99.4%, clarithromycin 98.5%, clindamycin 99.9%, erythromycin 96.5% and penicillin 100%. These results indicate that antimicrobial resistance is not yet a problem of S. pyogenes in Canada.

Adolescent↗
PubMed2000

Trends in antimicrobial susceptibility of bacterial pathogens isolated from patients with bloodstream infections in the USA, Canada and Latin America. SENTRY Participants Group.

From January through June of 1998, 4579 bloodstream infections (BSI) due to bacterial pathogens were reported from SENTRY hospitals in Canada, the USA and Latin America. Staphylococcus aureus, Escherichia coli, and coagulase-negative staphylococcus (CoNS) were the most common pathogens, together accounting for 55.2% of all BSI during this time period. Compared with the 5794 BSI reported from SENTRY from January through June of 1997, no major change was seen in the frequencies of occurrence of the most common bacterial causes of BSI. Between 1997 and 1998, the major change in antimicrobial resistance was an increase in oxacillin-resistance in both S. aureus and CoNS in all regions. These data demonstrate widespread antimicrobial resistance in Canada, Latin America and the USA, with a notable increase in oxacillin-resistance among staphylococci. Ongoing surveillance remains essential, and will enhance efforts to limit the scope of this worldwide problem.

Bacteremia↗
PubMed1998

Nineteenth century Canada: indigenous place of dis-ease.

During the nineteenth century period of intensive European Expansion into Canada, place was experienced with dis-ease by indigenous people. Not only was there less land available for people of the First Nations to live on as in the past centuries, but their intimate relationship with the land was disturbed causing a dis-ease, as their ability to experience place through ceremony was denied. The effects of this process of Euro-Canadian invasion within Canada created a sense of dis-ease, a sense of being out of place for indigenous people. It is my contention that in order to understand health, an awareness of the dynamic connection between a people and their land is needed, recognizing that a quintessential human quality is to imbue the world with meaning in the creation of sense of place. Through examination of a variety of published and unpublished material, archival sources, memos, letters, official documentation, I explore the effects of control of the place of First Nations, on the health and healing practices of the indigenous people.

Canada↗
PubMed1998

Standardization in health informatics in Canada.

Around the world, informatics has been cited as a key enabler of health sector reform. Recent reform programs in Canada, reflecting this global consensus, have emphasized the importance of quality information and information technology in meeting their goals. Standards are an important building block for achieving the required comprehensive and integrated health information infrastructure. This paper describes the current status of, and future plans for, health informatics and related standards in Canada.

Canada↗
PubMed2006

Sex ratio of multiple sclerosis in Canada: a longitudinal study.

BACKGROUND: Incidence of multiple sclerosis is thought to be increasing, but this notion has been difficult to substantiate. In a longitudinal population-based dataset of patients with multiple sclerosis obtained over more than three decades, we did not show a difference in time to diagnosis by sex. We reasoned that if a sex-specific change in incidence was occurring, the female to male sex ratio would serve as a surrogate of incidence change. METHODS: Since environmental risk factors seem to act early in life, we calculated sex ratios by birth year in 27 074 Canadian patients with multiple sclerosis identified as part of a longitudinal population-based dataset. FINDINGS: The female to male sex ratio by year of birth has been increasing for at least 50 years and now exceeds 3.2:1 in Canada. Year of birth was a significant predictor for sex ratio (p<0.0001, chi(2)=124.4; rank correlation r=0.84). INTERPRETATION: The substantial increase in the female to male sex ratio in Canada seems to result from a disproportional increase in incidence of multiple sclerosis in women. This rapid change must have environmental origins even if it is associated with a gene-environment interaction, and implies that a large proportion of multiple sclerosis cases may be preventable in situ. Although the reasons why incidence of the disease is increasing are unknown, there are major implications for health-care provision because lifetime costs of multiple sclerosis exceed pound1 million per case in the UK.

Adult↗
PubMedDate not supplied

From nursing outposts to contemporary midwifery in 20th century Canada.

Knowledge of the history of one's profession is always related to the informed practice of the profession and can aid midwifery in its expansion and recognition. Understanding the long and diverse history of Canadian midwifery expands the appreciation by midwives in the United States of midwifery north of our border, which, although newly regulated, has much experience to share. This article documents the evolution of midwifery in Canada during the 20th century. Government-sanctioned midwifery prior to 1991, the year when Ontario passed legislation to regulate midwifery for the first time in modern Canadian history, was limited to isolated, usually northern, frontier and outpost regions of Canada, but the providers who practiced it were well-educated and important figures in the broader history of midwifery.

Canada↗