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Aneurysmal bone cyst of the ilium associated with pregnancy.

A 19-yr-old primigravida presented with a back mass which was found to originate from the right ilium and was associated with oblique fetal lie. Elective caesarean section and excision of the mass were done. Histologically, the lesion proved to be an aneurysmal bone cyst. Review of bone tumors associated with pregnancy is presented, with discussion of the problems related to diagnosis of this condition.

Adolescent↗

Spontaneous resolution of simple bone cysts.

OBJECTIVE: To determine whether spontaneous resolution of simple bone cysts (SBC) is possible. METHODS: Ten patients were diagnosed as SBC on clinical and radiographic criteria and followed up for 1 to 7 years (mean 3.8). The degree of resolution was assessed subjectively by four radiologists and objectively by changes in the grey level histogram. RESULTS: All cases remained asymptomatic over the follow-up period. One of the lesions was considered static, two were increased, six remodeled and one resolved. The mean difference in grey levels between the lesion and the contralateral normal mandible decreased in 8 out of 10 cases. CONCLUSION: It is probable that SBC resolves spontaneously. A protocol for clinical and radiographic diagnosis and follow-up is proposed.

Adolescent↗

[Aneurysmal bone cysts of the base of the skull].

On the basis of two observation of aneurysmatic bone cysts in the region of the skull, the diagnostic and therapeutic problems of this clinical picture are discussed. The highest diagnostic value is offered by computed tomography. The operation with a total extirpation to be aimed at is recommended.

Adult↗

[Transverse myelopathy caused by aneurysmal bone cyst of the thoracic vertebra in an old person].

A 63-year-old woman developed progressive weakness and sensory disturbance in the legs, and had to walk with a stick three months later. Neurological examination revealed symptoms of transverse myelopathy at the level of the first lumbar cord. The plain X-rays revealed flattening and osteolytic changes of the 11th thoracic vertebra which suggested a spine tumor. CT showed a destruction of the 11th vertebra which invaded the spinal canal. The 11th vertebral body and the arches were filled by lobulated tumor masses. MRI of the spine revealed the 11th vertebra to be low in T1 and high in T2 images with marked spotty enhancement effect by gadolinium. The neighboring discs and spines were not involved by the tumor. The tumor was surgically resected with resultant massive bleeding. Histological diagnosis of the tumor was aneurysmal bone cyst. She developed a postoperative stress ulcer with perforation, but recovered. Finally she was able to walk without a stick nine months after surgery. Aneurysmal bone cyst, though very rare in elderly persons, should be considered in differentiating spine diseases which cause transverse myelopathy. It is important to make a preoperative diagnosis because severe bleeding may occur during a surgical procedure, as was seen in our case.

Bone Cysts, Aneurysmal↗

[Aneurysmal bone cyst arising in the rib; report of a case].

We experienced with a relatively rare case of an aneurysmal bone cyst (ABC) arising in the left rib. A 34-year-old female, had experienced chest discomfort on the left anterior side and pain for 1 year. A chest X-ray suggested a left chest wall tumor involving the ribs. Computed tomography (CT), magnetic resonance imaging (MRI) and a bone scintigram revealed an expansive tumor of the anterior portion of the left 4th rib involving the 3rd and 5th rib with "blow out appearance" and "fluid-fluid level". Wide excision of the tumor and adjacent muscle tissue was performed with an antero-axillary incision. Chest wall reconstruction was performed with prolene mesh (140 x 90 mm). The resected specimen showed an encapsulated bony mass (75 x 60 x 35 mm) with multiple blood-filled spaces. Histopathological diagnosis was an ABC originating in the left 4th rib. She has been doing well with no evidence of recurrence 12 months postoperatively.

Adult↗

[Aneurysmal bone cyst or giant cell tumor. The value of x-ray diagnosis for differential diagnosis].

Depending on analysis of radiographic morphology, location and patient's age of 72 aneurysmal bone cysts (ABC) and 47 giant cell tumours (GCT), the following criteria suggest an ABC with a high positive predictive value: location in the diaphysis (100%), in the shaft (92%), in the metaphysis or metadiaphysis (86%), patient younger than 17 years (97%) and growth rate grade Lodwick-IA (88%). GCT were selected via the following criteria: epimetaphyseal location (82%) and growth rate grade Lodwick-II (100%). In 14% of the cases, differential diagnosis between both entities is radiologically impossible.

Adolescent↗

[Aneurysmal bone cyst of the thoracic and lumbar spine. Report of 4 personal cases and description of an improved radical operation technic].

This report presents results in 4 cases of aneurysmal bone cyst of the thoracic- and lumbar spine with inclusion of the vertebral body. A new own modified radical method of resection (transthoracic or retroperitoneal) for the total resection of the lesion is described. The defect created after vertebral body resection is filled with a homologous femoral head transplant (prepared from material removed during total hip replacement). For correction of the deformity (kyphosis) and stabilisation of the area of VDS-Implant System of Zielke is used. The results thus obtained are excellent, complications or recurrences of the lesion have not been observed.

Adolescent↗

Fine-needle aspiration biopsy of solid aneurysmal bone cyst in the humerus.

We report the fine-needle aspiration biopsy (FNAB) cytology findings of a solid aneurysmal bone cyst in the left humerus of a 69-yr-old woman. Radiographically, the lesion showed an extensive, relatively well-defined osteolysis in the diaphysis, with a pathologic fracture. FNAB smears of the lesion consisted of benign, mononuclear cells and numerous osteoclast-like multinucleated giant cells. Some clusters of the mononuclear cells were closely associated with dense, homogeneous, extracellular, matrix material. To our knowledge, the FNAB features of solid ABC of the long bones have not been described previously in the English-language literature. The cytologic features are indistinguishable from those of giant cell tumors of bone and brown tumors of hyperparathyroidism.

Aged↗

Total destruction of the fourth metacarpal bone by aneurysmal bone cyst: reconstruction with strut fibular graft--a case report.

Total destruction of the fourth metacarpal bone by aneurysmal bone cyst is presented. Despite the benign nature of the lesion on plain radiograms, magnetic resonance imaging (MRI) has revealed total destruction of metacarpal bone with shelling off the articular cartilages on both ends of the metacarpal. Both adjacent dorsal interosseous muscles were also involved with tumour. After removal of the metacarpal bone and third and fourth interossei, fibular bicortical strut graft was used for reconstruction. Arthrodesis was done both at the carpometacarpal and metacarpophalangeal (MCP) joints. The follow-up radiograms at one year revealed excellent incorporation of the graft with no evidence of local recurrence. A careful pre-operative work-up including MRI seems necessary even in lesions that look typically benign with intraosseous location on plain radiograms. This approach may prevent unpredicted morphologic picture during surgery, high recurrence rate and the number of operations.

Adult↗

Unicameral bone cyst of the talus.

The authors present a rare case of a talar unicameral bone cyst in a 9-year-old boy. This is the first such case presented in podiatric literature; the lesion has been cited infrequently in world literature. A brief review of the literature is discussed, along with the diagnostic tests, possible complications, and proper therapy for this lesion.

Bone Cysts↗

Concurrent osteoblastoma and aneurysmal bone cyst of the ethmoid sinus: case report.

A unique case of osteoblastoma and aneurysmal bone cyst of the ethmoid sinus is reported. A causal relationship may exist between the two entities. The computed tomography appearance consisted of a dense lesion with a thin sclerotic rim containing a low-attenuation center, causing ethmoid sinus enlargement. Similar radiologic appearances are seen with other less rare pathologies.

Adolescent↗

Aneurysmal bone cyst of the clavicle in a child.

We report a case of an aneurysmal bone cyst (ABC) of the clavicle in a 9-year-old boy, which initially presented as a pathological fracture of a benign cystic lesion. ABC of the clavicle is rare in children less than 10 years old and radiological diagnosis may prove difficult in the early stages of presentation.

Bone Cysts, Aneurysmal↗

Aneurysmal bone cyst of the coronoid process of the mandible.

A rare case of an aneurysmal bone cyst (ABC) involving the right coronoid process of the mandible in a 12-year-old girl is presented. The characteristic features with fluid-fluid levels within the lesion observed on Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) was helpful in the preoperative diagnosis.

Bone Cysts, Aneurysmal↗

[Case of aneurysmal bone cyst in sternal manubrium].

A 27-year-old female who suffered from aneurysmal bone cyst in sternal manubrium, which is histologically confirmed, underwent sternal manubriumectomy. Tumor was totally resected. Manubrial defect was replaced with two metal plates, which joined both stumps of the second ribs and both sternal ends of clavicles, respectively, and wide Marlex mesh. Using non-absorbable sutures, two metal plates were fixed to the mesh, and the mesh was also secured to surrounding structures, to hold the normal function of thorax and shoulder joints.

Adult↗

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.

BACKGROUND: Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), or Nasu-Hakola disease, is a presenile dementia associated with loss of myelin, basal ganglia calcification, and bone cysts. It is caused by recessively inherited mutations in two genes encoding subunits of a cell membrane-associated receptor complex: TREM2 and DAP12. The clinical course of PLOSL has not been characterized in a series of patients with TREM2 mutations. METHODS: The authors compare neurologic and neuroradiologic follow-up data of six patients carrying TREM2 mutations with PLOSL due to defective DAP12 genes. The authors review the known mutations in these two genes. RESULTS: Mutations in DAP12 and TREM2 result in a uniform disease phenotype. In Finnish and Japanese patients with PLOSL, DAP12 mutations predominate, whereas TREM2 is mutated more frequently elsewhere. CONCLUSIONS: Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy should be considered in adult patients under age 50 years with dementia and basal ganglia calcification. Radiographs of ankles and wrists, and DNA test in uncertain cases, confirm the diagnosis.

Adaptor Proteins, Signal Transducing↗