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PubMed1975

Relations between behavioral characteristics of infants, their mothers' behaviors, and performance on the Bayley Mental and Motor Scales.

Bayley Mental scores were significantly related to several concurrent ratings of infant and maternal testroom behavior when firstborn black male infants were 14 months (N equals 49), 18 months (N equals 34), and 22 months of age ( equals 32). With increasing age, social responsiveness played a relatively less important role in successful performance, while object responsiveness became increasingly important. Bayley Motor scores were related to many fewer ratings than the Mental scores. Gross Muscle Coordination was related to performance at all three ages, and Energy ratings at two of the three ages. For both the Mental and Motor scores, fewer relationships were observed at the 18-month testings as compared to the 14 and 22-month testings. By 22 months, infants scoring higher on the Bayley Mental scale had mothers who were more highly involved with their child's achievement as judged by testroom behaviors.

Black or African American↗

PubMed1988

[Intrinsic results of behavior as primary determinants of behavioral choice].

The present experiment was designed to test the hypothesis that the intrinsic results of behavior are powerful determinants of behavioral choice. Cooperative and independent building-blocks were studied with thirty-six kindergarten children arranged in pairs and assigned to one of the following three groups: the cooperation group in which subjects were shown a film indicating that the product (the intrinsic result) of two models working cooperatively is greater than the product of two models working independently in building blocks; the cooperation-estimation group in which subjects were shown films revealing that a cooperative model positively evaluates both cooperation and good work results; and, a control group in which no films were shown to subjects. Children in the two experimental groups observed their respective films four times. The building-blocks of all pairs were observed on ten occasions. Results indicated that children's choice of a cooperative strategy was facilitated by the presence of a large product (work) which they were given to understand was the result of cooperatively-minded models or children working together. This suggested that a good product tended to evoke positive feelings. On the other hand, choice of a cooperative strategy was inhibited by the anticipation of a negative intrinsic result (i.e., unacceptable work) of cooperation and children chose to work independently as a consequence.

Child Behavior↗

PubMed1979

Tolerance to the behavioral effects of phencyclidine: the importance of behavioral and pharmacological variables.

The effects of phencyclidine (PCP) on the behavior of rats responding to a fixed-interval 1 min schedule of water delivery were determined before, during, and after a period of daily PCP injections. The effects of acute PCP on overall response rate were biphasic: low doses increased and high doses decreased rates. In addition, PCP produced a dose-related decrease in quarter-life and high doses of PCP decreased the number of reinforcers delivered. During the daily injection regimen roughly a two-fold tolerance developed to the effects of 8.0 mg/kg PCP on response rate in animals receiving either presession or post-session injections of this dose, emphasizing the predominance of pharmacological variables in PCP tolerance. However, slight differences between these groups in tolerance development and in the rate of tolerance loss demonstrate that behavioral variables can influence tolerance to the behavioral effects of PCP.

Animals↗

PubMed1992

Age-related changes in behavioral components in relation to changes in global Type A behavior.

The current study is one of a series of studies undertaken to investigate long-term changes of the Type A behavior pattern (TABP) in surviving subjects of the Western Collaborative Group Study. Behavioral components were scored for 565 Structured Interviews (SI) of returning subjects using a recently developed methodology. Scores were compared with component ratings from the 1960-1961 intake interviews to isolate specific elements of change and evaluate their magnitude in relation to changes in global TABP. Test-retest correlations for seven behavioral components of the SI support the notion of moderate stability ranging in value from .29 to .55. Significant mean changes in component scores were observed for Type A Content, Exactingness, Competitiveness, and Hostility. Changes in Competitiveness and Hostility were Type A dependent, showing reliable increases in Type A subjects but not in Type B subjects. The observed changes in Hostility, Competitiveness, and Exactingness support the overall change in the Type A direction observed in previous analyses of these data.

Adult↗

PubMed2000

What happens when capitated behavioral health comes to town? The transition from the Fort Bragg demonstration to a capitated managed behavioral health contract.

Capitated managed care contracts for behavioral health services are becoming more prevalent across the country in both public and private sectors. This study followed the transition from a demonstration project for child mental health services to a capitated managed behavioral health care contract with a for-profit managed care company. The focus of the study was on the impact--at both the service system and the individual consumer level--pertaining to the start-up and maintenance of a capitated managed behavioral health program. A case study using multiple methods and multiple sources of information incorporated a program fidelity framework that examined micro to macro levels of program implementation. The findings of this study include the following: access to services decreased, the lengths of stay and average daily census in the more intensive levels of treatment declined, difficult-to-treat children were shifted to the public sector, and ratings of service system performance and coordination fell.

Adolescent↗

PubMedDate not supplied

Learning behavior, escape behavior, and depression in an ulcer susceptible rat strain.

The aim of the present study was to explore the relationship between depression (helpless withdrawal behavior) and susceptibility to stress ulcer in rats. The WKY genetic strain of rats has been described as highly susceptible to stomach ulcer development during water restraint, i.e., when placed in a jar of water and forced to swim to keep their head above water, a setting in which Richter identified "giving up" behavior akin to hopelessness (Richter, 1957). Since WKY rats tended to float in the water instead of swimming in an attempt to escape, and were also found to be relatively inactive in open field tests, a series of experiments were performed to ascertain whether their diminished activity and their failure to swim reflected slowness, cognitive impairment, or something actually akin to depression. The latter interpretation was supported by evidence from tests of shock avoidance behavior, of capacity to learn discrimination in an operant setting, and by the capacity of an antidepressive drug to lessen floating time in the forced swim test and also to reduce the incidence of stomach ulcers.

Animals↗

PubMed1986

Multivariate assessment of locomotor behavior: pharmacological and behavioral analyses.

A Behavioral Pattern Monitor (BPM) is described which is designed to assess the spatial and temporal sequences of the locomotor movements, investigatory holepokes, and rearings of rats. The system records these behavioral responses with 0.1 sec resolution in time and 1.5 inch resolution in space, and permanently stores all the resulting data. The sequences of these responses may then be displayed on a video terminal or on paper and are also available for the calculation of a variety of descriptive statistics. Studies are described in which rats were tested repeatedly without any pharmacological treatments or in single test sessions following the administration of saline or one of five stimulant drugs. A variety of descriptive measures of the temporal or spatial patterning of the animals' behavior are described and applied to the data resulting from the studies of the various stimulants. It is concluded that the combination of these measures enables distinctions to be made among these drugs which cannot be made on the basis of measures of the amount of locomotor activity.

Amphetamine↗

PubMed1988

Behavioral tolerance to cocaine in squirrel monkeys: acute and chronic effects on complex operant behavior.

Four food-deprived squirrel monkeys were trained to emit complex sequences of responses. The sequences involved pressing lighted response keys in orders dictated by colors that illuminated the keys, and ranged in length from two to five responses. Appropriate completion of these behavioral chains could be followed by food presentation. Acute administration of a range of doses (0.1-1.7 mg/kg) of cocaine hydrochloride produced dose-related decreases in the rate of completing chains and in accuracy of performance during chains. There was little evidence that the drug's effects on overall accuracy were related to the length of the chain. Three of the monkeys were exposed to daily administration of a large dose of cocaine, first after daily sessions and then prior to sessions. Daily postsession administration did not alter the dose-effect curves, but daily presession injection did, indicating the development of behavioral or "contingent" tolerance. In all cases, tolerance was accompanied by an increase in reinforcement frequency relative to the frequency observed following acute administration. Omission of the daily dose during presession drug administration resulted in performance near original control levels indicating essentially no withdrawal effect. The findings illustrate the importance of behavioral factors in the development of tolerance to cocaine in a primate.

Animals↗

PubMedDate not supplied

Nonopiate effects of alpha-neo-endorphin on mouse behavior using multi-dimensional behavioral analyses.

The effects of alpha-neo-endorphin on mouse behavior were investigated by using a multi-dimensional behavioral analyser (Animex II) which classifies animal's movements into nine degrees. The intracerebral injection of alpha-neo-endorphin (30 micrograms) significantly decreased the 1/1, 1/2 and 1/4 sizes of movement (linear locomotion and rearing) within 15 min after injection. None of the effects were significantly affected by naloxone even at high doses. The results suggest that a behaviorally active site within the alpha-neo-endorphin sequence is capable of quite potent but nonopiate effects.

Animals↗

PubMedDate not supplied

Reduction of motor behavioral deficits in senescent animals via chronic prolactin administration. I. Rotational behavior.

The effects of chronic prolactin administration on amphetamine or dopamine (DA) induced rotational behavior was examined in mature (6 month) and senescent (24 month) Wistar rats which were unilaterally lesioned in the left substantia nigra with 6-hydroxydopamine. Prolactin (150 ng/hr) was administered for 7 days via subcutaneously implanted Alzet minipumps. Amphetamine (AMPH) (0, 10 micrograms) or DA (0, 25 micrograms) was administered through cannula which had been implanted into the right (intact) striatum. Both DA-active agents were given prior to pump implantation and on day 4 of prolactin administration. The AMPH was dissolved in saline (1 microliter; pH, 5.5-6.0), while DA was dissolved in N2 bubbled distilled H2O (1 microliter; pH, 5.5-6.0) and the animals were pretreated with nialamide (50 mg/kg) intraperitoneally 1 hr before DA or DA-vehicle injection. The order of drug administration was counterbalanced within the age groups. Results showed that both groups of animals exhibited higher rotational behavior scores following prolactin treatment. In fact, there was a trend toward greater enhancement of rotational behavior in the senescent animals following prolactin treatment than that seen in mature animals. These results parallel those reported previously wherein it was found that striatal DA receptor concentrations (as assessed with [3H]spiperone binding) were higher in prolactin treated mature and senescent animals than in their respective controls. The findings suggest that there is a relationship between increases in the density of striatal DA receptors and improvement in motor performance tasks in senescent animals.

Aging↗

PubMed2006

Is speeding a "real" antisocial behavior? A comparison with other antisocial behaviors.

The relationship between speed and crashes has been well established in the literature, with the consequence that speed reduction through enforced or other means should lead to a reduction in crashes. The extent to which the public regard speeding as a problem that requires enforcement is less clear. Analysis was conducted on public perceptions of antisocial behaviors including speeding traffic. The data was collected as part of the British Crime Survey, a face-to-face interview with UK residents on issues relating to crime. The antisocial behavior section required participants to state the degree to which they perceived 16 antisocial behaviors to be a problem in their area. Results revealed that speeding traffic was perceived as the greatest problem in local communities, regardless of whether respondents were male or female, young, middle aged, or old. The rating of speeding traffic as the greatest problem in the community was replicated in a second, smaller postal survey, where respondents also provided strong support for enforcement on residential roads, and indicated that traveling immediately above the speed limit on residential roads was unacceptable. Results are discussed in relation to practical implications for speed enforcement, and the prioritization of limited police resources.

Adolescent↗

PubMed2005

Acute and chronic cocaine behavioral effects in novel versus familiar environments: open-field familiarity differentiates cocaine locomotor stimulant effects from cocaine emotional behavioral effects.

Cocaine is a potent stimulant drug, but its stimulant effects can be substantially modulated by environmental novelty versus familiarity. In this report, we varied exposures to a novel environment as a way to assess the impact of environmental familiarity versus novelty upon the locomotor activation induced by acute and chronic cocaine treatments. In experiment 1, the effects of 1 (PE1) versus 0 (PE0) pre-exposures to the test environment were compared for their impact upon the locomotor stimulant, central zone entry and grooming effects induced by an acute cocaine (10 mg/kg) treatment. In experiment 2, the effects of 10 (PE10) versus 0 (PE0) pre-exposures upon the cocaine effects were compared. Experiment 3 assessed the effects of nine cocaine treatments (10.0 mg/kg) initiated in a novel environment (PE0) versus familiar environment (PE10). In all experiments, cocaine had a potent locomotor stimulant effect in a novel environment, which was attenuated by environmental familiarity such that in PE10 groups, cocaine did not reliably induce an acute locomotor stimulant effect. Environmental novelty/familiarity, however, did not reliably alter cocaine effects upon central zone penetration, grooming behavior, or the neurochemical effects induced by cocaine. In the chronic treatment regimen, the PE0 group exhibited a tolerance-like decrease in locomotor activation, but the PE10 group exhibited a sensitization-like increase in locomotor activation. Despite the marked directional changes in the locomotor stimulant effects of cocaine treatments, initiated in a novel (PE0) versus familiar (PE10) environment, the same asymptotic levels of locomotor activation were achieved. In contrast, the behavioral measures of central zone activity progressively increased with repeated treatments regardless of whether the environment was initially novel (PE0) or familiar (PE10). Thus, habituation factors can profoundly alter the locomotor stimulant effects of cocaine and can induce pseudo-tolerance phenomena. In contrast, central zone activity undergoes sensitization-like effects independent of habituation state and therefore appears to represent a more fundamental behavioral effect of cocaine. In that, central zone penetration in an open-field is linked to emotional processes; this finding is of substantial importance in understanding the effects of repeated cocaine usage.

Acute Disease↗

PubMed1997

Behavioral assessment of relaxation: the validity of a Behavioral Rating Scale.

Poppen (Behavior Relaxation Training and Assessment, 1988) has developed an observational method of assessing the degree to which individuals show a relaxation response. Although promising, this method, the Behavioral Rating Scale (BRS), has yet to be thoroughly investigated. Subjects in this study were randomly assigned to a progressive relaxation training group or an attention-control group. Following a training period, subjects participated in a laboratory session in which self-report measures of relaxation were obtained, physiological measures were monitored, and behavioral observations were made using the BRS. Results supported the use of the BRS as a valid, observable measure of an individual's relaxation response. Discriminant validity was demonstrated by between-group differences on the BRS and construct validity was shown by significant correlations between changes on the BRS and changes on self-report and physiological measures. It is argued that, though alternative explanations are feasible, this study's results support the use of the BRS as an effective assessment tool when measuring an individual's response to progressive muscle relaxation.

Adolescent↗

PubMed2001

Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects.

BACKGROUND: We have examined the effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in the rat. METHODS: Rats were pretreated daily with saline or nicotine for 20 days then challenged with nicotine or saline on day 21. Animals were trained in a classical conditioned fear paradigm. Dopamine utilization in the medial prefrontal cortex and nucleus accumbens shell and conditioned fear stress-induced immobility responses were assessed. RESULTS: Saline pretreated animals rapidly acquired the conditioned fear stress response as assessed by preferential activation of mesoprefrontal dopamine metabolism and tone-elicited immobility responses. Repeated, but not acute, nicotine pretreatment significantly reduced conditioned fear stress-induced dopamine metabolism in the medial prefrontal cortex and nucleus accumbens shell. Repeated nicotine pretreatment did not modify the acquisition or expression of conditioned fear stress responses, however. CONCLUSIONS: The dissimilar effects of repeated nicotine exposure on the cortical dopamine and behavioral responses to conditioned fear stress suggest that nicotine differs from other agents with anxiolytic activity that produce coordinated changes in conditioned fear stress-induced cortical dopaminergic and behavioral responses. Furthermore, compared with results of acute footshock stress, repeated nicotine pretreatment appears to have differential effects on physical versus psychological stressors. Results are discussed within the clinical context of stress-related psychopathology syndromes and comorbid nicotine dependence.

Animals↗

PubMed2003

Behavioral adjustment of siblings of children with autism engaged in applied behavior analysis early intervention programs: the moderating role of social support.

There have been few studies of the impact of intensive home-based early applied behavior analysis (ABA) intervention for children with autism on family functioning. In the present study, behavioral adjustment was explored in 78 siblings of children with autism on ABA programs. First, mothers' ratings of sibling adjustment were compared to a normative sample. There were no reported increases in behavioral adjustment problems in the present sample. Second, regression analyses revealed that social support functioned as a moderator of the impact of autism severity on sibling adjustment rather than a mediator or compensatory variable. In particular, siblings in families with a less severely autistic child had fewer adjustment problems when more formal social support was also available to the family. The implications of these data for future research and for practice are discussed.

Adaptation, Psychological↗

PubMed1997

A cross-cultural comparison of behavior disturbance and suicidal behavior among psychiatrically hospitalized adolescents in Israel and the United States.

American adolescent psychiatric patients had significantly higher levels of suicidal behavior (49% vs. 19%) and a higher percentage of depression diagnoses (78% vs. 24%) than Israeli psychiatric inpatients. After controlling for the diagnosis of depression, American male patients obtained significantly higher scores on the Obsessive-Compulsive, Aggression, and Hyperactive subscales of the Child Behavior Checklist (CBCL) than the Israeli males. American females scored higher on the Depression subscale than Israeli females. Differences may be attributed to less tolerance or differing perceptions of deviant behavior in America, clinical practice, and/or the CBCL's greater applicability to American inpatient samples.

Adolescent↗

PubMed1986

Type A behavior in children: demographic, behavioral, and physiological correlates.

This article provides descriptive data on the Type A behavior pattern from an urban, biracial sample of 8 to 10-year-old children from Minneapolis. Type A behavior was assessed using the Matthews Youth Test for Health (MYTH). High MYTH scores were more prevalent in males relative to females and in black males relative to white males. Parent self-reports suggested that Type A children were more outgoing, talkative, and physically active than Type B children; they were more aggressive in their interactions with others and were more likely to experience a greater number of aversive significant life events than Type B children. No differences in resting heart rate, diastolic or systolic blood pressures were found between Type A and Type B children; there were no differences on measures of the family environment. These results provide additional evidence for the construct validity of the MYTH and offer new information on the correlates of Type A behavior in children.

Blood Pressure↗

PubMed1987

Ontogeny of spatial navigation behaviors in the rat: dissociation of "proximal"- and "distal"-cue-based behaviors.

Rats can use both "proximal" and "distal" cues to locate goal objects in their environments (Morris, 1981). In the proximal-cue situation, local stimuli that spatially co-occur with the goal are available to guide behavior. In the distal-cue situation, there are no cues that co-occur with the goal object; thus to directly locate the goal, the rat must learn about the spatial location of the goal relative to distal cues. Using the Morris water maze, we found that these two navigation behaviors are dissociated during ontogeny. Rats only 17-days-old are capable of using proximal cues to locate a safe platform. It was not until the rats were 20-days-old, however, that they began to display minimal evidence of distal-cue utilization. Control experiments indicated that the 17-day-old subjects' failure on the distal problem was likely due to their inadequate spatial learning skills. These results were interpreted within a Jacksonian perspective of brain-behavior relations.

Aging↗