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The centrifugal effect and other spatial artifacts of topographic EEG mapping.

Topographic maps of EEG can contain artifacts that are foreign to clinical electroencephalographers trained to read traditional EEG records. Several spatial artifacts are described and discussed here, including the centrifugal effect, ring enhancement, spatial aliasing, electrode hills and holes, color-step effects, and restriction of minima/maxima to electrode sites. Users of quantitated EEG with topographic maps should be aware of these artifacts and should have a high suspicion for other analogous artifactual spatial phenomena when interpreting individual patient records.

Color↗

A method for correcting bone induced artifacts in computed tomography scanners.

A method that corrects for artifacts in X-ray transmission scanners created by the alteration of the energy spectrum by bone is described. The method involves two reconstructions of the pictures: the first establishes the approximate distribution of bone and the second enables the artifacts to be eliminated. The first reconstruction is needed to establish the total amount of bone along each ray. Assuming that the X-ray energy spectrum is known, it is shown how the line integrals can be corrected. The method was tested on several mathematical phantoms as well as on human head data. The nonlinear nature of the spectral artifacts is shown to produce streaks in certain phantoms.

Bone and Bones↗

Artifact simulating chronic extracerebral fluid collections on computed tomography of the head.

Accurate analysis in computed tomography of the brain requires recognition of artifacts that may lead to an erroneous diagnosis or at least confuse the examination. An artifact that mimics chronic extracerebral fluid collections is described; it can occur with the Picker 600 scanner. One should be aware that an artifact can be machine specific, depending on the reconstruction and design differences of the scanner.

Child, Preschool↗

Edge artifacts in MR images: chemical shift effect.

The boundaries of some organs as seen in clinical magnetic resonance images appear to be asymmetric. This effect is caused by chemical shift differences between the resonant frequencies of the hydrogen nuclei of water and fat. The zeugmatographic technique maps resonant frequencies to unique spatial locations. These differences in resonant frequencies can appear as artifactual misplacement of information as this one-to-one correspondence is lost. Various phantoms are used to demonstrate that the boundary artifact appears only in the direction of the read (frequency-encoding) gradient when media of two different chemical shifts are separated by an interface. When the relative shift is less than the width of the interface, the boundary appears to be asymmetric; when the relative shift is greater than the width of the interface, a bright band is seen along one edge with a dark band along the other. This artifact is more pronounced in low resolution images than in high resolution images, and these effects are seen even when the relative chemical shift is smaller than a pixel bandwidth. These effects are explained both conceptually and analytically. The clinician should be aware of the potential presence of this artifact at boundary interfaces that bear diagnostic significance.

Kidney↗

Motion artifact suppression technique (MAST) for MR imaging.

A technique has been developed that significantly improves the image resolution and reduces motion artifacts in conventional two-dimensional Fourier transform and three-dimensional Fourier transform magnetic resonance imaging sequences. Modifications on the gradient waveforms completely refocus the transverse magnetization at the echo time, regardless of the motion occurring between the time of the 90 degrees radiofrequency excitation and the echo time (within-view). This accomplishes suppression of motion artifacts and regains the signal from flowing blood and CSF. Images of the head, abdomen, chest, and spine are reproduced which show the increase in signal and anatomical detail that would otherwise be degraded and lost in artifact noise. This technique has reduced the practical difficulty of obtaining clinically diagnostic T2-weighted abdominal images. It also has allowed diagnostic quality T1- and T2-weighted images to be obtained with one acquisition per view, thus reducing the total scan time.

Brain Stem↗

Round CT film static artifacts: simulation of focal pathology.

Spot-like or smudge-like film artifacts produced by static electric discharges may mimic lesions when superimposed on filmed CT images. These artifacts are typically round with a dark center that fades peripherally. Automatic film loading, low atmospheric humidity, and dirty film cassettes increase production of these artifactual pseudolesions. Misdiagnosis is prevented by familiarity with the artifacts' appearance and review of images on the viewing console.

Diagnosis, Differential↗

Improvement in signal-to-noise ratio and reduction of chemical shift and motion-induced artifacts by summation of gradient and spin echo data acquisition.

Narrow bandwidth magnetic resonance (MR) imaging allows an increase of signal-to-noise ratio (SNR) but causes increased chemical shift and motion-induced artifacts. To obtain MR images with SNR approximately equal to that obtained with narrow bandwidth but with less chemical shift and motion-induced artifact, we introduced triple readout gradient reversal centered around the spin echo. As a result, signals from two gradient echoes and a single spin echo can be collected and summed. Phantom, knee, shoulder, and abdominal MR images were obtained using a 1.5 T GE Signa System at sampling rates ranging from 10 to 60 kHz. Since the bandwidth per pixel was tripled, chemical shift misregistration was reduced by the same factor. The summation image of two gradient echoes and one spin echo had an SNR comparable with that of a single spin echo acquired within the same total sampling interval. Data acquisition at a high sampling ratio also minimizes the dispersion of T2* weighting among three echoes. In addition, summation of the three resulting images decreases motion artifact by effective averaging.

Abdomen↗

Potential misinterpretation of cervical spondylosis with cord compression caused by metallic artifacts in magnetic resonance imaging of the postoperative spine.

Tiny metallic particles produced by the contact of untempered surgical instruments with a diamond drill produce magnetic susceptibility artifacts that can both limit the diagnostic quality of postoperative magnetic resonance imaging of the cervical spine and cause diagnostic error. A case of cervical pseudospondylosis with apparent cord compression due to such an artifact is presented. The source of these metallic particles is considered, and the nature of the susceptibility artifact is discussed.

Female↗

Artifact in optical pachometry with contact lenses in situ.

We describe a measurement artifact associated with the wearing of a contact lens during optical pachometry. The contact lens essentially magnifies the image of the cornea, creating a nonphysiological apparent increase in corneal thickness. This artifact ranges from 0.27 to 1.22% with four current extended wear hydrogel lenses, depending on lens thickness and index of refraction. The implications of this artifact are discussed relative to study design and interpretation of results for contact lens-induced corneal edema.

Contact Lenses↗

Soft tissue artifact compensation in knee kinematics by double anatomical landmark calibration: performance of a novel method during selected motor tasks.

The purpose of the present work was to describe and assess the performance on two selected subjects of a new method for the compensation of soft tissue artifact on knee rotations and translations during the execution of step up/down, sit-to-stand/stand-to-sit, and flexion against gravity. Soft tissue artifact has been recognized as the most critical source of error in gait analysis data. Its propagation strongly affects joint angles, in particular those characterized by a small range of motion, such as knee ab/adduction and internal/external rotation. This may be critical in the exploitation of gait analysis data for clinical decisions. The proposed method is based on the flexion/extension angle interpolation of two anatomical landmark calibrations taken at the extremes of motion. Its performance on knee rotation and translations was tested on a kinematics data-set obtained by the synchronous combination of traditional stereophotogrammetry and 3-D fluoroscopy. The newly proposed method was extremely effective on the compensation of soft tissue artifact propagation to knee rotations, in particular mean values of the root mean square error on ab/adduction and internal/external rotation angles decreased from 3.7 degrees and 3.7 degrees to 1.4 degrees and 1.6 degrees, respectively, with respect to single calibration. Mainly, knee translations calculated from stereophotogrammetric data using the proposed compensation method were found to be reliable with respect to the fluoroscopy-based gold standard. The residual mean values of the root mean square error were 2.0, 2.8, and 2.1 mm for anterior/posterior, vertical, and medio/lateral translations, respectively.

Aged↗

Efficient Monte Carlo based scatter artifact reduction in cone-beam micro-CT.

Cupping and streak artifacts caused by the detection of scattered photons may severely degrade the quantitative accuracy of cone-beam X-ray computed tomography (CT) images. In order to overcome this problem, we propose and validate the following iterative scatter artifact reduction scheme. First, an initial image is reconstructed from the scatter-contaminated projections. Next, the scatter component of the projections is estimated from the initial reconstruction by a Monte Carlo (MC) simulation. The estimate obtained is then utilized during the reconstruction of a scatter-corrected image. The last two steps are repeated until an adequate correction is obtained. The estimation of the noise-free scatter projections in this scheme is accelerated in the following way: first, a rapid (i.e., based on a low number of simulated photon tracks) MC simulation is executed. The noisy result of this simulation is de-noised by a three-dimensional fitting of Gaussian basis functions. We demonstrate that, compared to plain MC, this method shortens the required simulation time by three to four orders of magnitude. Using simulated projections of a small animal phantom, we show that one cycle of the scatter correction scheme is sufficient to produce reconstructed images that barely differ from the reconstructions of scatter-free projections. The reconstructions of data acquired with a charge-coupled device based micro-CT scanner demonstrate a nearly complete removal of the scatter-induced cupping artifact. Quantitative errors in a water phantom are reduced from around 12% for reconstructions without the scatter correction to 1% after the proposed scatter correction has been applied. In conclusion, a general, accurate, and efficient scatter correction algorithm is developed that requires no mechanical modifications of the scanning equipment and results in only a moderate increase in the total reconstruction time.

Algorithms↗

Two-year-olds will name artifacts by their functions.

Do young children take functional information into account in naming artifacts? In three studies of lexical categorization, 112 children 2 years of age learned new names for novel artifacts with novel functions and then extended the names to new objects. The objects were designed to have functions that were causally related in simple and compelling ways to perceptible aspects of their physical structure. Despite only minimal opportunity to familiarize themselves with the objects, children generalized the names in accordance with the objects' functions. This result obtained even when children had to discover the functions of the named objects on their own (Experiment 2) and when all the test objects had some discernible function (Experiment 3). Two-year-olds name by function when they can make sense of the relation between the appearances and the functions of artifacts.

Analysis of Variance↗

Children's reliance on creator's intent in extending names for artifacts.

When children learn a name for a novel artifact, they tend to extend the name to other artifacts that share the same shape--a phenomenon known as the shape bias. The present studies investigated an intentional account of this bias. In Study 1, 3-year-olds were shown two objects of the same shape, and were given an explanation for why the objects were the same shape even though they were intended to be different kinds. The shape bias disappeared in children provided with this explanation. In Study 2, 3-year-olds were shown triads of objects, and were either given no information about the function of a named target object, told the function that object could fulfill, or told the functions all three objects were intended to fulfill. Only in the third condition did children overcome a shape bias in favor of a function bias when extending the name of the target object. These findings indicate that 3-year-olds' shape bias results from intuitions about what artifacts were intended to be.

Child, Preschool↗

When children ask, "What is it?" what do they want to know about artifacts?

When children ask, "What is it?" are they seeking information about what something is called or what kind of thing it is? To find out, we gave 2-, 3-, and 4-year-olds (32 at each age) the opportunity to inquire about unfamiliar artifacts. An ambiguous question was answered with a name or with functional information, depending on the group to which the children were assigned. Children were inclined to follow up with additional questions about the object when they had been told its name, but seemed satisfied with the answer when they had been told the object's function. Moreover, children in the name condition tended to substitute questions about function for ambiguous questions over the course of the session. These results indicate that children are motivated to discover what kinds of things novel artifacts are, and that young children, like adults, conceive of artifact kinds in terms of their functions.

Child, Preschool↗

the role of dimensional distinctiveness in children's and adults' artifact categorization.

There are conflicting results as to whether preschool children categorize artifacts on the basis of physical or functional similarity. The present study investigated the effect of the relative distinctiveness of these dimensions in children's categorization. In a physical-distinctive condition, preschool children and adults were initially asked to categorize computer-animated artifacts whose physical appearances were more distinctive than their functions. In a function-distinctive condition, the functional dimension of objects was more distinctive than their physical appearances. Both conditions included a second stage of categorization in which both dimensions were equally distinctive. Participants in a control condition performed only this stage of categorization. Adults in all conditions and stages consistently categorized by functional similarity. In contrast, children's categorization was affected by the relative distinctiveness of the dimensions. Children may not have a priori specific beliefs about how to categorize novel artifacts, and thus may be more susceptible to contextual factors.

Adolescent↗

Relevance of sonographic artifacts observed during in vitro characterization of urocystolith mineral composition.

Nine pure mineral type canine uroliths (bladder or urethral origin only) were imaged ultrasonographically using 3.5 MHz, 5.0 MHz, and 7.5 MHz fixed focus, mechanical sector transducers in a urinary bladder phantom. The uroliths studied were those composed of 100% magnesium ammonium phosphate, calcium oxalate monohydrate, calcium oxalate dihydrate, calcium phosphate appatite, and calcium hydrogen phosphate dihydrate (brushite), ammonium acid urate, sodium acid urate, cystine, and silica. The occurrence of both reverberation/streak and acoustic shadowing artifacts were compared to urocystolith mineral type (classified by effective atomic number), urocystolith width, urocystolith height (thickness), and ultrasonographic imaging frequency. No predictable relationship was found between either of the artifacts seen beyond the urocystolith (reverberation/streak or the acoustic shadowing) and urocystolith mineral type. There was no statistical relationship between the occurrence of reverberation/streak artifact and the size (width or height) of the urocystolith or the ultrasonographic frequency. There was, however, a statistically relevant relationship between ultrasonographic imaging frequency and the occurrence of acoustic shadowing and between urocystolith height (thickness) and the occurrence of acoustic shadowing. However, regardless of ultrasound frequency, acoustic shadowing was observed less than 35% of the time in any of the urocystolith mineral types examined. Based on the imaging of the bladder phantom supporting apparatus (7.0 mm bolts covered by plastic), the accurate characterization of a curved object surface directly facing the transducer was found to be directly related to the frequency of sound used for imaging and at best predictably limited to curved vs flat. Accurate measurement of the maximum transverse dimension of an echogenic curved object or accurate characterization of the lateral borders of such an object was considered unlikely with general ultrasonographic equipment of the frequencies studied. Therefore, detailed architectural characterization of urocystoliths suitable for mineral composition prediction is considered highly unlikely with general pulse-echo ultrasonographic techniques.

Animals↗

Effect of respiratory gating on reducing lung motion artifacts in PET imaging of lung cancer.

Positron emission tomography (PET) has shown an increase in both sensitivity and specificity over computed tomography (CT) in lung cancer. However, motion artifacts in the 18F fluorodioxydoglucose (FDG) PET images caused by respiration persists to be an important factor in degrading PET image quality and quantification. Motion artifacts lead to two major effects: First, it affects the accuracy of quantitation, producing a reduction of the measured standard uptake value (SUV). Second, the apparent lesion volume is overestimated. Both impact upon the usage of PET images for radiation treatment planning. The first affects the visibility, or contrast, of the lesion. The second results in an increase in the planning target volume, and consequently a greater radiation dose to the normal tissues. One way to compensate for this effect is by applying a multiple-frame capture technique. The PET data are then acquired in synchronization with the respiratory motion. Reduction in smearing due to gating was investigated in both phantoms and patient studies. Phantom studies showed a dependence of the reduction in smearing on the lesion size, the motion amplitude, and the number of bins used for data acquisition. These studies also showed an improvement in the target-to-background ratio, and a more accurate measurement of the SUV. When applied to one patient, respiratory gating showed a 28% reduction in the total lesion volume, and a 56.5% increase in the SUV. This study was conducted as a proof of principle that a gating technique can effectively reduce motion artifacts in PET image acquisition.

Algorithms↗

Correction for spectral artifacts in cross-sectional reconstruction from x rays.

A monoenergetic response correction is described which, along with adequate filtration, may be used to remove the spectral shift artifact encountered in three-dimensional reconstruction from x rays. Reconstructions were carried out by means of a convolution algorithm for simulated data using this method. These are compared with reconstructions obtained using fixed-length water-bath scans as a remedy for the special artifact. These studies suggest that the spectral artifact can be successfully eliminated from computerized cross-sectional scans without resorting to the use of the water bath while, at the same time, improving quantum statistics and/or permitting operation at a lower tube current.

Filtration↗