Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Trace Elements”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 829 records · Page 46Linked to original sources
PubMed1982

Trace elements in tissues from New Zealanders: a compilation of published data.

The information currently available on the levels of trace elements in New Zealand autopsy material is reviewed. Concentrations of copper, manganese, zinc, selenium and cadmium have been reported in a variety of tissues from fetuses, infants and adults, nickel and lead in some fetal tissues and adult liver, and arsenic, bismuth, cobalt, mercury, silver and thallium in adult livers. Except for Se levels, which are markedly lower, and Cu levels which are at the lower end of the range for adults, levels of trace elements are generally similar to those reported from other countries.

Adolescent↗
PubMed1971

Radionuclides and selected trace elements in marine protein concentrates.

The concentrations of various trace elements and radionuclides have been measured in marine protein concentrates prepared from surface feeding fishes. As with concentrates prepared from benthic fishes, the 210Pb-210Po pair are the most significant radionuclides present. Concentrations of stable Pb, Co and Ag in certain concentrates are sufficiently high to contribute substantially to estimated current intakes of these elements.

Animals↗
PubMed2005

Comparison of sample preservation methods for clinical trace element analysis by inductively coupled plasma mass spectrometry.

The effects of chemical additives and storage temperatures on measurement of 16 trace elements in urine by inductively coupled plasma mass spectrometry (ICP-MS) were evaluated. A 24-hour urine specimen was supplemented with concentrations of the elements. Aliquots containing 1 of 4 chemical additives were stored at 3 different temperatures in sealed polypropylene containers. Elemental concentrations were determined by ICP-MS for the resulting samples after 1, 2, 8, and 65 days of storage. Initial element concentrations measured within 8 hours of specimen preparation were consistent with expected concentrations (except for aluminum). For most elements, preservation and storage conditions yielded consistent measured concentrations throughout the experiment. Notable exceptions were for aluminum (general rise over time) and mercury (general decrease over time). Adding boric acid and potassium pyrosulfate resulted in sample contamination; elemental contamination was concentration-dependent for both. Although little microbial contamination was observed during the experiment, refrigeration of samples is recommended to curtail bacterial growth in nonsterile specimens. In light of these results, refrigerated urine storage without the use of chemical additives is an effective preservation method for ICP-MS analysis of many trace elements.

Humans↗
PubMed2006

[Determination of trace elements in Spirulina platensis (Notdst.) Geitl. by flame atomic absorption spectrometry combined with microsampling pulse nebulization technique].

The contents of trace elements Ni, Zn, Mn, Cu, Mg, Fe, Ca and Pb in Spirulina platensis (Notdst.) Geitl. were determined by flame atomic absorption spectrometry combined with microsampling pulse nebulization technique. The results of the determination show that Spirulina platensis (Notdst.) Geitl. are rich in the inorganic elements such as Mg, Zn, Fe, Ca and Cu. Its recovery ratio obtained by standard addition method ranged between 96.58% and 106.12%, and its RSD was lower than 4.26%. The result will provide scientific data for the study on the trace elements in Spirulina platensis (Notdst.) Geitl. and on their relativity of efficacy of medicine.

Calcium↗
PubMed2003

Characterisation of trace elements and methylmercury in an estuarine sediment reference material, IAEA-405.

An estuarine sediment sample, IAEA-405, was recently characterised for trace elements and methylmercury (MeHg) for ultimate use as a marine reference material. The reference values were calculated using data sets from 120 laboratories that participated in a world-wide intercomparison exercise. The data evaluation is highlighted, and includes comparisons of different analytical methods, as well as the distribution of data. Overall laboratory performance for this exercise was encouraging: 86 laboratories (72%) reported data with <25% outliers. There was sufficient acceptable data to establish recommended values for 17 elements and information values for a further 15 elements. In addition, a recommended value was established for methylmercury. The estuarine sediment sample, IAEA-405, can be used as a reference material for quality control in the determination of trace elements and methylmercury in moderately polluted sediments.

Environmental Monitoring↗
PubMed1995

[Administration of multivitamin combinations and trace elements in diabetes].

BACKGROUND: Many free radicals are formed in diabetes mellitus due to the oxidative stress in hyperglykemia. The objective of the investigation was to evaluate the influence of an antioxidant mixture and trace elements on some biochemical parameters in controls and diabetic patients. METHODS AND RESULTS: 13 controls (6 men and 7 women, the average age was 53 years) and 9 diabetic patients (4 men and 5 women, the average age was 52 years) were supplemented with multivitamin mixture and trace elements with respect to antioxidant activities. Both groups received the same amount of the mixture, controls 50 days, diabetic patients 35 days. Blood samples were measured before and after the treatment. Renal, liver tests and acid-base balance were not influenced. Apolipoprotein A increased significantly (p < 0.05). Glycosylated hemoglobin in the diabetic group decreased significantly from 9.4 +/- 1.6 to 7.2 +/- 1.5 mumol fructose/g of hemoglobin (p < 0.01). In the diabetic group increased the levels of ionorganic phosphorus from 0.99 +/- 0.08 to 1.15 +/- 0.13 mmol/L (p < 0.01), zinc from 10.4 +/- 1.3 to 14.3 +/- 1.7 mumol/L (p < 0.01), copper from 20.3 +/- 2.3 to 25.9 +/- 6.3 mumol/L (p < 0.05) and selenium in blood from 0.96 +/- 0.21 to 1.65 +/- 0.38 mumol/L (p < 0.001). Selenium in blood of the control group increased from 0.88 +/- 0.26 to 1.66 +/- 0.34 mumol/L (p < 0.001). The activity of superoxide dismutase (SOD) in diabetic group increased from 598 +/- 105 to 696 +/- 103 U/g of hemoglobin (p < 0.01), the activity of glutathion peroxidase (GSHPx) did not change, malondialdehyde (MDA) decreased from 7.1 +/- 1.1 to 5.8 +/- 1.1 mumol/L (p < 0.01) and uric acid decreased from 261 +/- 83 to 236 +/- 96 mumol/L (p < 0.01). CONCLUSIONS: Multivitamin mixture with trace elements significantly protects diabetic patients and the control group against injurous actions of free radicals. That is confirmed by the decrease of plasmatic malondialdehyde and uric acid and by the increase of superoxide dismutase in erythrocytes. The decrease of glycosylated hemoglobin reduces the probability of diabetic complications, the increase of plasmatic Zn and Se in the diabetic group increased the plasmatic antioxidant ability.

Diabetes Mellitus↗
PubMed1989

[Clinical significance of the measurement of trace elements in the gastric mucosa and their oxides in patients with spleen diseases and gastric cancer].

The gastric mucosa trace elements and oxides were investigated with X-ray energy disperse analysis system in 41 cases of gastric disease due to Spleen deficiency. The differences in the change of the quantity of Zn, Cu, ZnO and CuO were very significant (P less than 0.05-0.001) in the gastric mucosa between normal area and focal area, between Spleen Qi deficiency and Spleen deficiency with Qi stagnation, and between benign gastric disease and gastric cancer. The experiments showed that: (1) The trace elements in the organism form its own system, the values being within the relatively constant scope. (2) The ratios of Zn/ZnO and Cu/CuO reflected "the rate of effectual utility" of Zn and Cu. (3) There was a very close internal relation between Spleen deficiency with Qi stagnation and gastric cancer. (4) The quantitative changes of Zn, Cu, ZnO, CuO, Zn/ZnO and Cu/CuO were related to pathologic change and the TCM syndrome pattern, and is worthy of further research.

Adult↗
PubMed1997

Analysis of trace elements in the hair of volunteers suffering from naso-pharyngeal cancer.

This article describes a study where the trace elements (TEs) of four groups of volunteers were analyzed. The volunteers were divided into four groups A, B, C, and D. Group A was made up of healthy subjects, group B was made up of volunteers who had just been diagnosed as having naso-pharyngeal cancer (NPC), group C was made up of volunteers who had been diagnosed as having NPC after 3 mo of treatment, and group D was made up of volunteers who had been diagnosed as having NPC after 6 mo of treatment. In all groups, 11 trace elements in hair were analyzed. Our study shows that the concentrations of zinc (Zn), copper (Cu), manganese (Mn), and cobalt (Co) in group B are less than that of group A, whereas the concentration of titanium (Ti) in group B is higher. Our results also show that the difference in the level of TEs between group A and the other groups is dramatically decreased as the time of the treatment is increased. This may be a reflection of successful treatment.

Absorption↗
PubMed2000

[Analysis of trace elements in liver, spleen and brain of rats infected with Toxoplasma gondii].

OBJECTIVE: To study the level of five trace elements(Fe2+, Cu2+, Zn2+, Ca2+, Mg2+) in the liver, spleen and brain of the rats infected with Toxoplasma gondii. METHODS: 20 rats were randomly and equally divided into two groups: normal group and experimental group. On the 64th day after injection of 1.5 x 10(6) T. gondii/2 ml, all of the rats were killed and the atomic absorption method were used. RESULTS: Compared with the normal group, the level of Cu2+ in liver in experimental group was significantly reduced (P < 0.01), and the amount of Fe2+ of sick rats were higher than that of the normal (P < 0.01). No differences in the content of Zn2+, Ca2+, Mg2+ between the experimental and control group were determined; the level of Fe2+, Cu2+ in spleen in experimental group was significantly altered (P < 0.01). The amount of Mg2+ of sick rats were higher than that of the normal (P < 0.01), and no difference on the content of Zn2+, Ca2+ between the experimental and control group were estimated; the level of Fe2+, Cu2+, Mg2+ in brain in experimental group was significantly reduced (P < 0.01). The amount of Ca2+ of sick rats were higher than that of the normal (P < 0.02). No difference on the content of Zn2+ between the experimental and control group were estimated. CONCLUSION: T. gondii infection might cause changes in trace elements in the liver, spleen and brain of rats.

Animals↗
PubMed2003

Trace element concentration in various tissues following fluoride administration to female mice.

Brain, liver, kidney and muscles demonstrate significant changes in essential trace element (Cu, Zn, Mn and Fe) level in adult female mice given 30, 60 and 120 ppm sodium fluoride (NaF) in drinking water. These changes involve excess removal or accumulation of these trace elements in respective tissues. Changes observed were dose dependent and significant at 120 ppm NaF concentration in drinking water.

Animals↗
PubMed1976

Surface predominance of trace elements in airborne particles.

A number of minor and trace elements including Be, C, Ca, Cr, K, Li, Mn, Na, P, Pb, S, Tl, V, and Zn present in coal fly ash are found to be preferentially concentrated on the particle surfaces. Environmentally effective concentrations of these elements are thus much higher than indicated by conventional bulk analyses.

Air Pollutants↗
PubMed1999

Trace element and magnesium levels and superoxide dismutase activity in rheumatoid arthritis.

It has been suggested that reactive oxygen metabolites and trace elements play some role in the etiology and pathogenesis of rheumatoid arthritis (RA). Superoxide dismutase (SOD) is believed to exert an important protective role against oxygen toxicity. The aim of the study was to investigate the probable changes in the levels of trace elements and SOD activity in RA. Plasma and erythrocyte copper, zinc, and magnesium levels and erythrocyte SOD activity were measured in groups of controls and RA cases. Significantly increased erythrocyte SOD activity was found in RA patients in comparison with controls (p < 0.0001). A rise in erythrocyte Zn level (p < 0.0001) and plasma Cu level (p < 0.0001) and a decrease in erythrocyte Cu level (p < 0.05) and plasma Zn level (p < 0.05) were obtained in RA patients when compared to controls. Plasma and erythrocyte Mg levels of the RA patients showed slight and statistically insignificant reductions when compared to controls (p > 0.05). In RA patients, there were positive correlations between erythrocyte SOD activity and Mg level (r = 0.4345, p < 0.01) and between erythrocyte Zn level and plasma Cu level (r = 0.4132, p < 0.01). There were negative correlations between erythrocyte SOD activity and plasma Zn level (r = -0.3605, p < 0.05) and between plasma Zn level and erythrocyte Cu level (r = -0.4578, p < 0.01) in RA patients.

Adult↗
PubMed2006

Determination of mineral and trace elements in some medicinal herbs and their infusions consumed in Turkey.

Fourteen mineral and trace elements (Al, Ba, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Ni, Pb, Sr and Zn) were determined in the herbs and their infusions consumed for medical purposes in Turkey such as chamomile (Matricaria chammomile L.), fennel (Foeniculum vulgare), linden (Tilia vulgaris), nettle (Urtica dioical), rosehip (Fr.Rosa caninae), sage (Salvia officinalis) and senna tea (Cassia anqustifolia). Microwave digestion procedure was applied under optimized conditions for dissolution of medicinal herbs. Element concentrations in the medicinal herbs and their infusions were determined by FAAS and ICP-AES. The accuracy and precision were verified against a GBW 07605 Poplar leaves and Tea certified reference material. The mineral and trace element content of medicinal herbs and their infusions showed a wide variability. However, distribution of the elements in the infusions is not high and it is nil especially for Cd, Co, Cr and Pb.

Beverages↗
PubMed1980

The influence of a high-bran diet on trace element retention in primates.

Proton-induced x-ray emission (PIXE) has become an established analytical method for the determination of trace elements in biomedical samples. The standard PIXE technique has been modified, resulting in a considerable improvement in detection limits. Refinements include the use of an external proton beam, the incorporation of a triggered beam-pulsing system, and the backward angle location (135 degrees to the incident ions) of the Si(Li) x-ray detector. The technique is now clearly capable of rapid, multielemental investigations, and requires a minimum of target preparation. Samples of liver and oesophagus tissue were obtained from 26 baboons at autopsy. Of these, 13 had been maintained on a semi-synthetic (high-bran) diet, with the remaining 13 forming the control group. Some 15 elements were analysed quantitatively; optimum detection limits were in the range 10-20 PPB (1 billion = 10(9). Clear differences were obtained: the high-bran diet is shown to produce imbalances in biologically active elements such as S, K, Ca, Ni Cu and Zn. These results are discussed on the basis of the phytate hypothesis, in terms of which trace elements in the diet are rendered physiologically unavailable to the subject.

Animals↗
PubMed1993

Concentrations of trace elements in the hair of the guinea pig. A review.

Various animal models have been employed for research on the significance of measuring trace element concentrations in the human scalp hair. The objects of such research were the establishment of relationships between the concentrations of trace elements in human scalp hair and (1) their concentrations in other compartments of the human body or (2) specific pathophysiological conditions. The guinea pig appears to be the animal of choice for such studies because the elemental composition and growth pattern of its hair parallel those of the human scalp hair.

Animals↗
PubMed1984

Mineral and trace element content of vegetarian diets.

Lacto-ovo, lacto, and vegan vegetarian diets were analyzed for calcium, phosphorus, magnesium, zinc, iron, and nitrogen at four calorie intake levels ranging from 1,700 to 2,800 kcal/day. Diets containing dairy products had a high calcium and phosphorus content, ranging from 1,279 to 1,755 mg calcium and 1,378 to 2,160 mg phosphorus for the four calorie levels, respectively, and vegan diets contained less calcium, ranging from 612 to 810 mg. The magnesium content of all three types of vegetarian diets was adequate or high, ranging from 366 to 560 mg/day. The zinc content was lower than that of the RDA (15 mg/day), and was particularly low at the 1,700 calorie intake levels of all diets. The iron content of these diets varied widely and ranged from 12.7 to 22.7 mg. This study has shown that vegetarian diets planned and presented at the higher calorie intake levels contain adequate amounts of minerals and trace elements, whereas this is not the case at the 1,700 calorie intake level. This observation is of importance as the mineral and trace element content of relatively low calorie vegetarian diets would not supply sufficient amounts of these nutrients. In addition, the bioavailability of minerals and trace elements from these diets remains to be determined.

Calcium↗