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At least 829 records · Page 46Linked to original sources
PubMed2004

Thyroglossal duct lesions in childhood--a review of experience in Nigerian children.

This is a retrospective study of 36 children with thyroglossal duct lesions managed at a tertiary hospital in Nigeria, between 1993 and 2003. The aim was to determine the pattern of presentation and outcome of management. The majority of patients presented with a chronic thyroglossal sinus with associated recurrent inflammation. The location and relationship of the lesions to the hyoid bone were similar to those encountered in the rest of the world. Despite their well-documented clinical features, thyroglossal duct lesions were misdiagnosed in some patients. The main complications were surgical site infections and recurrence. A plea is made for clinicians to pay attention to clinical and operative details so as to diagnose these lesions accurately and manage them properly.

Child↗
PubMedDate not supplied

[Surgical reinterventions in neck after elective procedures].

OBJECTIVE: Our objective was to determine the frequency of surgical reinterventions for recurrence or disease persistence after elective surgical procedures of the neck. METHODS: We used a transversal and comparative study, accomplished during a 6-year period. Emergency initial surgical procedures were excluded. The patients were divided according to the type of hospital where the initial surgical procedure was performed--those treated at a specialized medical center and those operated on in general hospitals. The variables evaluated were preoperative and pathological diagnosis, previous surgical procedures, and the time between the primary surgery and the definitive procedure. RESULTS: Three hundred sixty-two cases were included. Of these, 27 patients (7.45%) required surgical reinterventions. Time elapsed between the first and the definitive procedure was 1 to 19 years. Diagnostic concordance between the initial and final diagnosis was 89%. According to the type of hospital where the initial procedure was performed (specialized vs. general hospitals), we observed the following reintervention frequencies: parathyroid, 12.2% vs. 12.2% (p = 0.6); thyroid, 1.63% vs. 5.88% (p <0.05); thyroglossal duct cyst, 1.65% vs. 5.83% (p = 0.41), respectively. CONCLUSIONS: The specialized hospital admits patients with multiple problems, poor response, or inadequate therapeutic indication. For thyroid pathologies the odds ratio established a probability of 6.8 for major reintervention in those patients treated in non-specialized hospitals.

Adult↗
PubMedDate not supplied

Role of scintigraphy in congenital thyroid anomalies.

Thyroid scintigraphy using Tc-99m pertechnetate is a frequently performed procedure in routine nuclear medicine practice. The indications for thyroid scintigraphy are investigation of hyperthyroidism, nodularity of the gland, cause of thyroid stimulating hormone elevation and localization of an ectopic thyroid gland. In the pediatric population, the most common request is for the evaluation of neonatal hypothyroidism. This imaging procedure is helpful in the identification of the underlying cause as well as in making a differential diagnosis. Early diagnosis is essential for appropriate therapy planning in this age group, and thyroid scintigraphy provides important diagnostic data. This article is written to review the scintigraphic findings in various congenital thyroid anomalies and to underline its use in the differential diagnosis.

Adolescent↗
PubMed1991

[Differentiated thyroid cancer on the thyroglossal duct].

Over one hundred cases of carcinomas located on the thyroglossal duct have been reported worldwide. Most of these tumors originally were differentiated thyroid cancers. Their biological behavior is the same as that of tumors of the thyroid gland itself. On the basis of one case discovered in an 11-year-old girl, who presented with regional and systemic metastases, we discuss the various aspects of their origin, diagnosis and treatment. As far as the latter is concerned, we think that these tumors can not always be treated by exeresis of the thyroglossal duct. On the basis of the analysis of situations in which these tumors may be encountered, we propose a carcinological surgery, which might possibly be more aggressive, on the thyroid and cervical lymphatic tissues.

Bone Neoplasms↗
PubMed1991

The re-emergence of scrofula with HIV infection: a review of epidemiology, pathogenesis, diagnosis and treatment.

Scrofula has been called "The Dangerous Masquerader" because of its propensity to mimic other diseases. Scrofula has been mistaken for metastatic carcinoma, regional neoplasms, thyroglossal duct cysts, fungal disease, toxoplasmosis, lymphoma, osteosarcoma, chondrosarcoma, bacterial adenitis, and collagen vascular disease. Because of the enormous number of infectious and neoplastic diseases acquired by the HIV positive population, the diagnosis of scrofula may be further delayed in some patients. In these patients the early diagnosis of scrofula might allow the early identification of HIV infection and the early institution of anti-retroviral therapy. The recommended duration of anti-tuberculosis therapy is also different in HIV positive patients. Therefore, to ensure the patient of the most beneficial therapy, the physician must always consider scrofula in the differential diagnosis of a neck mass, and particularly because of the increases incidence of intrapulmonary tuberculosis in AIDS patients, he must consider the possibility of HIV infection.

HIV Infections↗
PubMedDate not supplied

[Thyroglossal duct with papillary carcinoma. Report of a case].

We report the case of a 32-year old woman with an anterior cervical cystic mass originating in the thyroglossal duct. At surgical exploration, the mass was reacted, including the thyroglossal duct and the mid-portion of the hyoid bone (Sistrunk's procedure). The histopathologic study demonstrated a papillary carcinoma. Fine needle aspiration biopsies of both thyroid lobes were performed postoperatively without any histopathologic abnormalities. The patient was discharged without performing any other surgical procedure and without complications. Treatment with I131 and thyroid hormones was initiated, and at 11 months of follow-up, the patient is asymptomatic without any evidence of local or distant recurrence. The clinical and histopathological features are discussed, as well as the therapeutic options for this type of uncommon malignant neoplasm.

Adult↗
PubMed1979

Chemodectoma in the mid-thyroid region.

A chemodectoma (non-chromafin paraganglioma), which presented as a neck mass in the mid-thyroid region, is reported in a 36 year old female. Clinically, it resembled a thyroglossal duct cyst and on frozen section it looked like a thyroid adenoma.

Adult↗
PubMed1990

Papillary carcinoma of a thyroglossal duct remnant with Hashimoto's thyroiditis.

A rare case of papillary carcinoma of the thyroglossal duct remnant with Hashimoto's thyroiditis of the nonneoplastic ectopic thyroid tissue and the thyroid gland is described. The need for fine-needle aspiration cytologic examination in the management is stressed. The prognosis is excellent when the tumor is limited to the ectopic thyroid tissue and managed by a combination of the Sistrunk procedure and subtotal thyroidectomy followed by long-term thyroid suppression.

Adult↗
PubMed1989

A case report of papillary adenocarcinoma in sublingual region--ultrastructural and histochemical study.

A rare case of papillary adenocarcinoma located in the sublingual region is presented. This case was initially considered to be a hemangioma and then the tentative clinical diagnosis was thyroglossal duct cyst at the time of the operation under general anesthesia. However, the final histopathologic diagnosis was papillary adenocarcinoma. We investigated its origin by histological, ultrastructural and histochemical techniques and it was suggested that this tumor arose from the minor salivary gland.

Adenocarcinoma, Papillary↗
PubMed1989

Invasive thyroglossal duct carcinoma in childhood.

Thyroglossal duct carcinoma is a very rare tumor. Extracapsular invasion is even less common and can result in possible extension of the tumor into the surrounding musculature without metastatic lymphadenopathy. A case of a 13-year-old adolescent is presented to illustrate this problem. In this case a Sistrunk operation and total thyroidectomy followed by I131 ablation and thyroid hormone suppression was considered the treatment of choice.

Adolescent↗
PubMed1989

[Cervicofacial actinomycosis. Apropos of 2 atypical locations].

Cervico-facial actinomycosis is a chronic bacterial disease caused by actinomycetes. The diagnosis may be made on the specific anatomo-pathological appearance of the granulomas and be confirmed by anaerobic culture of the germs. The authors report two atypical cases: the first is a case of a thyroglossal pseudocyst, the second that of adenoidal vegetations in an adult. Treatment with Penicillin G or V for six weeks produced a favourable response. The various clinical forms of the condition described in the literature, should encourage the physician to include bacteriological testing for actinomycetes among his investigations.

Actinomycosis, Cervicofacial↗