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[Study on evaluation of fetal scalp tissue pH value during labor].

OBJECTIVE: To assess the predictive value of serial monitoring fetal scalp tissue pH value (tpH) during labor. METHOD: Fifty two primipara with singleton and cephalic presentation were recruited during their active phase of labor after rupture of membrane. Their fetal scalp tpH were determined by a new type of alloy pH spiral electrode and pH-LS-1 sensor. These values were compared with the umbilical blood pH values (bpH) measured immediately after delivery. RESULTS: The fetal tpH values were significantly positive correlated with the bpH values (r = 0.822 and 0.725). The incidence of neonate asphyxia in tpH >or= 7.20 group was significantly lower than those to tpH<7.15 group. No adverse effect was observed in this study. CONCLUSION: Determination of fetal scalp tpH during labor is of predictive value and harmless fro detecting fetal distress.

Body Fluids↗

Scalp necrosis in temporal (giant cell) arteritis:implications for the dermatologic surgeon.

Temporal arteritis, a variant of giant cell arteritis, is a systemic granulomatous vasculitis of large and medium-sized arteries. Usually the clinical features are dominated by ophthalmological and neurological complications. In rare instances, ischaemic necrosis, especially of the scalp, may lead patients to the dermatologist. We report a 76-year-old woman presenting with a unilateral scalp necrosis, accompanied by a dramatic ipsilateral impairment of vision. Immediately after duplex-sonography of the extracranial vessels and after initiation of corticosteroid therapy, the diagnosis of temporal arteritis was confirmed by temporal artery biopsy. One month later, because of insufficient secondary healing of the ulcer, the defect was covered by a mesh graft. The taking of the graft was delayed due to immunosuppressive therapy, but was complete. The patient unfortunately died as a result of complications related to surgical removal of an aspergilloma in the sphenoid cavity secondary to immunosuppressive therapy. We discuss the technique of artery biopsy and the possibility of surgical management of scalp necrosis in temporal arteritis.

Aged↗

Ultrastructural abnormalities in the dermal papillae of both lesional and clinically normal follicles from alopecia areata scalps.

Alopecia areata is a form of balding whose aetiology is uncertain. Although the dermal papilla in the hair bulb regulates the follicle and may play a part in the pathogenesis of alopecia areata, its ultrastructure has not been well described. As clinically normal, i.e. non-balding, follicles from alopecia areata scalps show abnormalities at the light microscope level, it would be expected that they should exhibit the earliest pathological changes involved in the dysfunction of the follicle. This study was designed to investigate the ultrastructure of normal human scalp follicular dermal papillae and to see if changes occurred in the ultrastructure of dermal papillae from either lesional or non-balding regions of alopecia areata. Normal dermal papillae contained well formed fibroblast-like cells with large, oval nuclei and well-developed endoplasmic reticulum; the cells were separated from each other by extracellular matrix containing small pieces of collagen and basal lamina-like material. Dermal papillae from both clinically normal and lesional alopecia areata follicles were less well organized and the dermal papilla cells exhibited signs of cell injury and contained abnormal amounts of pigment; an increased concentration of fibrous material in the extracellular matrix and thickening of the dermal papilla-epithelial junction were also seen. Follicles from lesional areas showed more pronounced changes than clinically normal ones. Ultrastructural abnormalities in the dermal papillae of clinically normal scalp follicles support the study of these follicles as a prime research target. The changes detected suggest that dermal papilla cells in alopecia areata would be less able to synthesize regulatory factors and that these may have more difficulty crossing into the epithelial compartment. They are consistent with an early pathological role for the dermal papilla in alopecia areata, but do not distinguish whether this is a primary aetiological role or a secondary response to an insult elsewhere in the follicle.

Adolescent↗

[A case of tension pneumocephalus due to scalp-ventricle fistula following trepanation after a 9-year interval].

We report a case of tension pneumocephalus due to scalp-ventricle fistula following trepanation surgery after a 9-year interval. A 68-year-old man had a past history of subarachnoid hemorrhage (unknown etiology) in 1987. At that time, he underwent an operation for ventriculoperitoneal (V.P) shunt and subduroperitoneal (S.P) shunt following ventricular drainage for hydrocephalus. He was admitted to our hospital with generalized convulsions on Feb. 26, 1996. On admission, he presented with disoriented consciousness and mild left hemiparesis. The skull films and CT showed abundant air collection in the bifrontal lobe mainly in the bilateral anterior horns of the lateral ventricle. We initially suspected air entry from frontal skull base fracture. However, a dimple was found on the right frontal scalp and connection between the dimple and the intracranial space was detected by fistulography. Scalp-ventricle fistula following trepanation was proved to be the air entry and it brought about tension pneumocephalus. On Mar. 6, closure of the fistula with a rotation skin flap was achieved. The collected air was completely absorbed, but a low-density area in the right frontal lobe remained on CT examination. We surmised that irreversible brain damage had been caused by longtime air exposure injury.

Aged↗

[TCD observation on cerebral blood flow dynamics inference of cerebral palsy with scalp therapy].

Through TCD test, observation on the blood flow dynamics change before and after treatment with 31 cases of the child cerebral atrophy was made. It is found that scalp therapy is able to speed up the blood flow of part artery, especially increase the even blood flow speed of MCA, ACA obviously (P < 0.05), which preliminary shows the mechanism of scalp therapy for child cerebral atrophy mean while. It is found that scalp therapy also has the function to restrain epilepsy.

Acupuncture Therapy↗

Hair tie-over dressing. A simple dressing for hair-bearing scalp wounds.

OBJECTIVE: To describe a temporary dressing for Mohs micrographic surgery wounds of the hair-bearing scalp. METHOD: The technique of using hair at the wound edges to hold down the dressing is described. RESULTS: This is an effective, simple, comfortable, and inexpensive scalp dressing, which our patients have found to be very acceptable. CONCLUSION: We consider that the hair tie-over dressing is an ideal temporary dressing for Mohs micrographic surgery wounds of the hair-bearing scalp.

Bandages↗

Alopecia areata. Autoreactive T cells are variably enriched in scalp lesions relative to peripheral blood.

BACKGROUND AND DESIGN: Alopecia areata is a condition characterized by hair loss in association with perifollicular infiltration of T cells and antigen-presenting cells. Autoreactive T cells are postulated to amplify this abnormality by interacting with DR+ follicular epithelium. These cells may recognize either autologous major histocompatibility complex class II antigen or an autoantigen restricted by major histocompatibility complex class II. Limiting dilution analysis was used to determine the frequency of autoreactive lymphocytes in scalp biopsy specimens and peripheral blood from seven adult patients with alopecia areata. Autoreactive T cells are defined for this study as those that proliferate in response to autologous irradiated peripheral blood mononuclear cells. RESULTS: Autoreactive lymphocytes were enriched in scalp biopsy specimens relative to peripheral blood in five of seven patients. This enrichment was statistically significant in four of five patients. Five autoreactive T-cell clones derived from lesional scalp were characterized. Four of these clones were CD3+CD4+CD8- and one clone was CD3+CD4-CD8+. CONCLUSIONS: Enrichment of autoreactive cells in lesions of alopecia areata supports a role for these cells in the pathogenesis of this condition. Enrichment of autoreactive lymphocytes is also found in allergic contact dermatitis. Thus, these autoreactive lymphocytes may have a general role in inflammation.

Adult↗

Angiosarcoma of the face and scalp, prognosis and treatment.

72 patients with angiosarcoma (AS) of the face and scalp have been analyzed with respect of various prognostic factors and the effects of different treatment regimes. This disease predominantly occurs in the elderly (age range, 56-92 years), and affects men rather more frequently than women (men: 44, women: 28). The clinical presentation varied, and included bruise-like lesions, dusky plaques, chronic edema or cellulitis, ulcerated nodules, pyoderma, and infected conditions. Due to lack of clinical awareness and problems with histologic assessment, delays in diagnosis were frequent. The majority of the tumors arose in the upper part of the face or scalp. Less commonly, the central part of the face was affected while only three tumors developed in the mandibular region. Overall the prognosis was poor; one half of the patients died within 15 months of presentation. Only 12% of the patients survived 5 years or more. Patients with lesions that were less than 10 cm in diameter responded better to treatment and statistically survived longer than those with larger lesions, emphasizing the crucial importance of early diagnosis. There is some indication that men, younger patients, patients with lesions on the central part of the face survived longer, but this was not of statistical significance. The histologic differentiation of the tumors at presentation also was of doubtful prognostic significance. Despite the overall poor prognosis, radical radiotherapy (mostly wide-field electron-beam therapy) in seven patients resulted in the apparent eradication of the local skin disease and prolonged survival of the patients. Pulmonary metastases developed 10 years later in two of those patients, however, but the face and scalp remained tumor-free.

Aged↗

Characteristics of medial temporal lobe epilepsy: II. Interictal and ictal scalp electroencephalography, neuropsychological testing, neuroimaging, surgical results, and pathology.

Sixty-seven patients with temporal lobe epilepsy without circumscribed, potentially epileptogenic lesions, who were studied with intracranial electrodes and who became seizure free following temporal lobectomy were retrospectively evaluated with regard to preoperative scalp electroencephalographic (EEG) findings, neuropsychological test results, neuroimaging findings, results of surgery, and pathology of resected tissue. Interictal scalp EEG showed paroxysmal abnormalities during prolonged monitoring in 64 patients (96%). These were localized in the anterior temporal region in 60 (94%) of these 64 patients. Bilateral independent paroxysmal activity occurred in 42% of the patients and was preponderant over the side of seizure origin in half. Ictal EEG changes were rarely detected at the time of clinical seizure onset, but lateralized buildup of rhythmic seizure activity during the seizure occurred in 80% of patients. In 13%, the scalp EEG seizure buildup was, however, contralateral to the side of seizure origin as subsequently determined by depth EEG and curative surgery. Lateralized postictal slowing, when present, was a very reliable lateralizing finding. Neuropsychological testing provided lateralizing findings concordant with the side of seizure origin in 73% of patients. When neuropsychological testing produced discordant results or nonlateralizing findings, those patients were usually found to have right temporal seizure origin. Intracarotid amobarbital (Amytal) testing demonstrated absent or marginal memory functions on the side of seizure onset in 63% of patients, but 26 patients (37%) had bilaterally intact memory. In those patients who had magnetic resonance imaging, it was very sensitive in detecting subtle medial temporal abnormalities. These abnormalities were present in 23 of 28 magnetic resonance images, and corresponded with mesial temporal sclerosis on pathological examination in all but 2 patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Brain↗

Source-density mapping of human visual receptive fields using scalp electrodes.

A triangular array of 20 electrodes spaced by 1.5 cm was used to record the distribution of current source-densities at 12 locations over the occipital scalp, in response to tachistoscopic presentation of a 1/2 degrees X 1/2 degrees scanning pattern element which explored a 2 degrees X 2 degrees area of the visual field. Single scalp locations had visual receptive fields of the order of 1 degrees-2 degrees in diameter, their shape varying somewhat according to the response in question. Source density analysis can resolve details of the AEP scalp map to better than 1 cm. Even with a 1/2 degrees X 1/2 degrees stimulus, averages of only a few tens of sweeps gave adequate signal-to-noise ratios.

Electrodes↗

Right/left differences of median nerve evoked scalp potentials in multiple sclerosis.

Scalp potentials evoked by electrical stimulation of the median nerve at the wrist were examined in multiple sclerosis patients and healthy controls. The latencies of the first negative peak (about 18 ms latency) of the response to right and to left-sided stimulation were compared. Forty-eight of 60 measured latency differences in 15 suspected or certain MS patients were more than 3 standard deviations beyond the average difference in controls (arbitrary norm limit), whereas none of the 56 results of the 14 controls was in that range. Fifteen of 24 latency differences in 6 patients without anamnestic or clinical sensory disturbances in the arms were above the limit. On the other hand, conduction velocity between wrist, neck and scalp did not differentiate controls from patients. We suggest using latency differences of the early components of right and left median nerve-evoked scalp potentials as a mean for the early detection of functional disturbances in multiple sclerosis.

Adult↗

Scalp marking of intracranial lesions using computed tomography (CT) images. A technical note.

A technique for scalp marking using computed tomography (CT) images is described. A reference marker is placed on the scalp and a plain lateral skull film is obtained. Using the CT scan image and the CT scout film, the target is marked on the plain skull film. The distance and angle of the target from the reference point on the plain film are measured and marked on the scalp to indicate the location of the target.

Brain Neoplasms↗

A special tissue expander in combination with extensive scalp-lifting.

Although posterior closure of male pattern baldness is usually accomplished in two procedures when using extensive scalp-lifting, there is the occasional patient who will require three operations because of very poor scalp laxity. A newly developed horseshoe-shaped tissue expander was designed for these patients so that a third procedure could be eliminated. This differential expander is actually placed during the first extensive scalp-lifting operation. This differs from the conventional placement as a separate preliminary operation. The significant salient features of this expander and the technique of placement are discussed in detail.

Alopecia↗

Scalp cavernous angioma presenting as sinus pericranii: diagnostic value of cerebral angiography and magnetic resonance imaging.

OBJECTS: Sinus pericranii is only a symptom complex, and it can have a variety of etiologies. Therefore, it is important to differentiate these etiologies preoperatively by means of radiological examinations. A 5-year-old boy was admitted with a soft and fluctuant tumor in the right parietal region near the midline. The tumor appeared when the child was in a recumbent position, distending noticeably with the Valsalva maneuver and disappearing completely when the patient was in the sitting position. METHODS: Magnetic resonance imaging showed the lesion with honeycomb-like heterogeneous iso- and low-intensity signals on the T1-weighted image and with heterogeneous high- and isointensity signal on the T2-weighted image. Dynamic study with an injection of gadolinium diethylene-triaminopentaacetic acid demonstrated and nodular peripheral enhancement at early phase and subsequent progressive enhancement towards the center of tumor. The internal carotid angiogram was normal. The external carotid angiogram, however, showed a tumor stain fed by the superficial temporal arteries. The stain was retained until the late phase and drained into the scalp veins and into the superior sagittal sinus. Following direct injection of contrast medium into the tumor there was prolonged retention of the medium in the tumor and leakage into scalp veins and the superior sagittal sinus. The mass under the periosteum was totally removed and proved to be a cavernous angioma. CONCLUSIONS: Scalp cavernous angioma is one of the etiologies of sinus pericranii and may be diagnosed preoperatively by cerebral angiography or magnetic resonance imaging. Serial dynamic magnetic resonance imaging will be particularly helpful for this diagnosis.

Cerebral Angiography↗

Scalp and depth recordings of induced deep cerebral potentials.

A balanced square wave was introduced between two adjacent depth electrodes implanted in the course of studying patients with intractable epilepsy and who were being considered for surgery. The stimulus current was designed so that charge density loading was well within limits of safety to avoid tissue damage. No neuronal activation was seen, and the stimulus intensity was significantly less than that used in subsequent stimulation session for the purpose of eliciting a clinical response and after-discharges. Averaging techniques were used to record the stimulus at distant electrodes both within the cerebrum and on the scalp. The recorded voltage decrement from the source was nearly identical with the theoretical voltage decrement predicted using principles of electric field theory in which the brain was assumed to be a homogeneous conductive medium. When the voltage recorded on the scalp was compared with the voltages recorded from depth electrodes, it was found that the effect of the highly resistive skull on voltage decrement was relatively less the more centric the source. This result also confirmed predictions based on electric field theory. Most significantly, voltages well within the physiologic range introduced in deep mesial temporal lobe structures were recorded from the scalp.

Brain↗

Spinal and early scalp-recorded components of the somatosensory evoked potential following stimulation of the posterior tibial nerve.

Somatosensory evoked potentials (SEPs) were elicited by stimulation of the posterior tibial nerve (PTN) in 12 normal adults. Recording using both cephalic and non-cephalic references were obtained from multiple electrodes placed over the spine and scalp. Following PTN stimulation, the fastest recorded potentials of the afferent sensory volley proceeds up the spinal cord at constant velocity. After arrival of the volley at cervical cord levels, 3 widely distributed waves, P28, P31 and N34, are recorded from scalp electrodes. These 'far-field' potentials are followed by a localized positivity (P38) which has a peak voltage either at the vertex or just laterally toward the side of stimulation. A contralateral negativity (N38) was present in most individuals. We propose that P28 arises from medial lemniscus; that P31 is generated by ventrobasal thalamus; and that N34 is probably the result of further activity in thalamus and/or thalamocortical radiations. The P38/N38 complex represents the primary cortical response to PTN stimulation. Its most consistent characteristic is a positivity at the vertex or immediately adjacent scalp areas ipsilateral to the stimulated leg. The topography of the P38/N38 potential varies slightly from individual to individual in a manner consistent with a functional dipole situated in the leg and foot area on the mesial aspect of the postcentral gyrus, whose exact location and orientation changes in accordance with known variations in the location of the leg area.

Adolescent↗

Scalp topography of the short latency somatosensory evoked potentials following posterior tibial nerve stimulation in man.

The scalp topography of the short latency somatosensory evoked potentials (SEPs) to unilateral posterior tibial nerve stimulation at the ankle was studied by using a non-cephalic reference in 22 normal young adults. At least 3 components (P28, N31 and N32) were identified preceding the major positive peak (P36). The first 2 components had similar peak latency at all scalp electrodes, and were considered to be generated in deep structures. However, N32 was localized to the hemisphere contralateral to the side of stimulation. P36 was maximal at the midline foot sensory area, or at the contralateral parasagittal area, and its amplitude decreased more steeply anteriorly than posteriorly. The peak latency of P36 progressively increased from ipsilateral to the side of stimulation in the coronal plane. P36 occurred earlier in the somatosensory area, and increased in peak latency anteriorly. Generator source of scalp-recorded far-field potentials (P28 and N31) remains to be elucidated. N32 might reflect activities of the thalamo-cortical pathway or an initial cortical response. P36 appeared to be generated in the somatosensory foot area.

Adult↗

Contrast and stereoscopic visual stimuli yield lateralized scalp potential fields associated with different neural generators.

The use of dynamic random-dot stereograms (RDS) allows to investigate evoked potential components generated exclusively by cortical structures. We analyzed the scalp distribution of stereoscopically evoked or contrast evoked potential field by recording electrical brain activity in 20 channels simultaneously from an electrode array covering the occipital scalp areas. Evoked brain activity was obtained from 13 healthy adults with dynamic RDS stimuli presented as a stereoscopic checkerboard pattern in the center, or in the right or left visual half-field. Such stereoscopically evoked scalp potential distributions were compared to those elicited by a conventional 2-dimensional checkerboard reversal stimulus of the same mean luminance and retinal extent. We found that the latencies of the major evoked components were similar for contrast and stereoscopic stimuli, while significant differences were observed when we compared the strength of the evoked potential fields or the topographical pattern elicited by lateralized stereoscopic and contrast stimuli. The functional relation of evoked electrical brain activity to the retinal stimulus location was significantly different for stereoscopic and contrast stimuli. We present evidence that stereoscopic perception relies on the activation of cortical structures in the human visual system that are different from those activated by comparable contrast stimuli, supporting the conclusions derived from our earlier electrophysiological experiments on stereoscopic vision. These data on the physiological correlates of processing of stereoscopic information in humans are in line with the results obtained with single neuron recordings from the cat and monkey visual cortex.

Adolescent↗