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At least 829 records · Page 46Linked to original sources
PubMed1979

Granular-cell tumors of the vulva: a report of three cases.

Three black women were found to have granular-cell tumors on the vulva; in one, there were several additionally in other cutaneous sites. Although this benign neoplasm is uncommon on the vulva, it should be considered in the differential diagnosis of nodular lesions on the vulva. Granular-cell tumors in multiplicity occur frequently and are not a sign of metastatic disease. This lesion has predilection for blacks. Pseudocarcinomatous hyperplasia occurs typically in overlying squamous epithelium and may be misinterpreted as squamous-cell carcinoma.

Adult↗
PubMed1987

Multiple cutaneous granular cell tumors in children.

Multiple cutaneous granular cell tumors are rare in childhood. We cared for two children with 15 and 6 tumors respectively. The tumors were asymptomatic nodules in the skin. Histologically, they consisted of large cells containing granules that were positive on periodic acid-Schiff stain and diastase resistant.

Child↗
PubMed1977

Granular cell myoblastoma.

Electron microscopic observations in three cases of granular cell myoblastoma revealed that this tumor is made up of two types of cells. 1) Granular cells grouped into nests, surrounded by a basement membrane, and displaying characteristic inclusions. Numerous processes were observed close to these cells, showing filamentous and microtubular components lying parallel to their axes. 2) Satellite fibroblasts which included angulated bodies. The relationship between these two types of cells is discussed.

Basement Membrane↗
PubMed1986

Granular-cell tumours of the skin do not express carcino-embryonic antigen.

Granular-cell tumour (GCT) of the skin is an uncommon tumour of disputed histogenesis, that has been subjected to several immunohistochemical studies. The controversy existing in the literature concerning the expression of carcinoembryonic antigen (CEA) by GCT prompted us to study a series of 17 cases of cutaneous GCT by using an avidin-biotin-immunoperoxidase technique on routinely-processed tissue sections. No CEA activity was detected in any of the tumours screened. The reasons for this controversy are discussed.

Carcinoembryonic Antigen↗
PubMed1986

Ameloblastoma with myofibroblasts: first report.

A recurrent infiltrative ameloblastoma of the mandible with a predominantly "follicular pattern" of the epithelial component is studied. The stroma contains abundant myofibroblasts; these cells have been described in benign and malignant infiltrative processes. This raises the question of the relationship between the presence of myofibroblasts and the aggressive behavior of a neoplasm.

Ameloblastoma↗
PubMed1987

Infiltrating orbital granular cell tumour: a case report and literature review.

A surgical biopsy of an infiltrative retrobulbar mass in a 44-year-old man was diagnosed as granular cell tumour. Electron microscopy and immunoperoxidase stains were used to confirm the diagnosis and to study the histogenesis of this rare soft tissue neoplasm. S-100 stain was positive, while neuron-specific enolase and myoglobin stains were negative, suggesting a non-specific neural origin for the cells. The capability of this tumour to invade surrounding tissues has seldom been described in the orbit and is demonstrated by this case.

Adult↗
PubMed1973

Sarcoma after injection of intramuscular iron.

Two cases are presented of sarcomata arising at the site of previous iron dextran injections. One of the tumours showed a histological pattern associated with iron dextran administration in animal experiments.

Adult↗
PubMed1979

Granular cell myoblastoma: positive staining for carcinoembryonic antigen.

An immunoperoxidase technique for the detection of carcinoembryonic antigen was applied to 10 cases of granular cell myoblastoma. Consistent, strong, intracytoplasmic granular staining, which can be easily interpreted, was obtained in all cases. Schwannomas, neurofibromas, dermatofibromas, and leiomyomas were negative. The test is helpful in confirming doubtful cases. The results tend to support the suggestion that granular cell myoblastoma is derived from perineural rather than endoneural cells.

Adult↗
PubMed2001

Inflammatory myofibroblastic tumor with CNS involvement.

BACKGROUND: Inflammatory myofibroblastic tumors (IMT) represent a spectrum of neoplasms that occur in the mesentery and retroperitoneum and less frequently in the mediastinum of children and young adults. Transformation into inflammatory fibrosarcoma and metastases are rare. CASE REPORT: We report the case of a 16-year-old patient with an inflammatory myofibroblastic tumor of the mesentery with mediastinal metastases. Partial remission was obtained by chemotherapy with ifosfamide, dactinomycine, and vincristine. Two months later, relapse with infiltration of the meninges developed, and the patient died. CONCLUSION: This case demonstrates unusual features of an IMT: presentation with metastases, excellent response to chemotherapy, dissemination to the CNS.

Adolescent↗