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PubMed1982

[Pathogenic mechanism, morphology, diagnosis and therapy of the rejection of the transplanted kidney].

A review of renal rejection is given. The immunology, morphology, clinical presentation, diagnosis and therapy of hyperacute, accelerated, acute and chronic rejection is given. Own data are given showing that repeated bedside renograms and repeated bedside sonograms are extremely helpful in confirming the rejection diagnosis especially in anuric patients. New fast fixation method is described, so morphological workup can be done within 4 h after renal biopsy is taken.

Biopsy↗
PubMed1994

[Prognostic factors in the course of kidney transplantation].

The success rate of kidney transplants is influenced by many factors. Analysis of the largest available collection of transplant data shows a statistical influence of HLA compatibility, immunosuppression with cyclosporin, donor age, preservation solution with preservation times longer than 24 h, and prophylactic treatment with anti-CMV immunoglobulin in transplants from CMV-positive donors to CMV-negative recipients. Type and duration of pretransplant dialysis and recipient age were not shown to have a significant influence. These results demonstrate that the analysis of retrospective data allows a quantitative estimation of the influence of risk factors. This knowledge can be utilized prospectively to improve the transplant success rate.

Adolescent↗