[Extraperiosteal osteochondromatosis].
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Two patients are described who developed heterotopic ossification after a minor trauma. The clinical symptoms, pathophysiology and treatment are discussed. We conclude that disabilities and handicaps will be limited by rehabilitation, which includes training of still available functions, and compensation for the lost functions by offering adaptive equipment and adjusting the circumstances. The treatment of patients with heterotopic ossification requires a multidisciplinary approach.
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Synovial chondromatosis is a rare condition that presents as juxta-articular masses which arise due to metaplasia of the synovia and formation of cartilaginous nodules. It will present as a monoarticular mass that is a chronically progressive condition without any tendency to resolve spontaneously. The authors present a review of the literature with a rare case study involving the ankle joint of a 29-year-old black male. The clinical presentation, surgical excision, histologic analysis, and postoperative course are discussed.
Two cases of post-traumatic transection of the popliteal artery in patients with exostosis of the lower extremities are reported. This complication does not seem to have been previously described in the literature. The pathogenetic, clinical, diagnostic and therapeutic aspects are analysed.
Pulmonary hypoplasia is a life threatening condition in newborns resulting from a generalized underdevelopment of the lungs. The lung disorder is usually secondary to conditions outside the lung such as thoracic volume reduction. The precise mechanism by which thoracic volume reduction prevents normal lung development and growth is unknown. As a model for human pulmonary hypoplasia associated with lethal skeletal dysplasia, a stereoscopic SEM study of chondrodystrophic (cho) fetal mouse lungs fixed by intratracheal instillation with 3% glutaraldehyde was conducted. In comparison with lungs of phenotypically normal littermates, the mutant's lungs appeared unaffected with respect to structure of major bronchiolar airways and in the morphology and amount of surfactant precursors (multilamellar bodies). The primary saccules within the mutant's lungs were significantly smaller and more numerous relative to those of normal littermates. These observations provide evidence that the lungs for this type of pulmonary hypoplasia are ultrastructurally normal with respect to upper airways, but that the primary saccules, or units of function in neonatal breathing in the rodent, are significantly smaller. This effect, however, does not appear to inhibit differentiation of type II pneumocytes or production of surfactant.
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An achondrogenic fetus, in whom the diagnosis was made prior to delivery by plain abdominal X-rays, is presented. The intrauterine characteristic roentgenographic manifestations are the short dense tubular bones of the extremities. An early diagnosis in fetuses with this disease can be made on a plain abdominal X-ray in the 22nd-24th week of gestation.