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Line bisection in normal adults: direction of attentional bias for near and far space.

The direction of attentional bias in forty normal adults was assessed using a computer generated line bisection task. A 4 (viewing distance)x4 (line length)x2 (cursor starting position) repeated measures factorial design was employed. As predicted, differences in bisection performance as a function of viewing distance were observed. The findings confirmed that scanning direction (contingent upon the starting position of the cursor), but not line length, significantly modulated this effect. The direction of bias across near and far space was further clarified yielding a progressive shift from a leftward bias in near space to a rightward bias in far space. A significant interaction of distance, line length and starting position revealed differential effects for left and right starting positions as a function of viewing distance and line length. More specifically, a leftward start witnessed deviations shifting progressively from left-to-right as distance and line length increased though no comparable pattern was observed for rightward starts. The results provide important behavioural support for the suggestion that dissociated neural systems may be responsible for attending and acting in near and far space and that other lateralised functions (such as scanning strategies) can influence hemispheric activation. The findings have relevant theoretical implications as well as important implications for the clinical assessment of unilateral neglect using a standard line bisection task, both of which are discussed.

Adolescent↗

Spatial behaviour is driven by proximal cues even in mildly impaired Parkinson's disease.

This investigation addresses the question whether patients with mild to moderate Parkinson's disease (PD) show spatial deficits in real-life settings. Therefore, a "search through"-locomotor task incorporating basic features of both the radial arm maze and the Morris water maze paradigms was used. The participants had to find and remember five out of twenty hidden locations within a completely controlled environment. Different spatial memory errors and inter-response intervals were recorded automatically. Fourteen patients with idiopathic PD and fourteen healthy controls matched for age, sex, handedness, and education were investigated. Patients and controls were widely comparable with respect to intelligence, verbal memory, and executive functions. Results show that performance deteriorated in about half of the patients if the starting position was moved by 90 degrees and the proximal cues were deleted simultaneously. This deficit was systematically related to specific measures of attention. Moreover, patients were less able to update their locomotor strategies towards a more effective strategy. Results are discussed with respect to the patient's inability to generate rules which can be flexibly used in changing environments, especially if proximal cues are removed. It is concluded that deficits in spatial behaviour can be elicited even in near-to-real-life situations if appropriate testing procedures are used.

Adult↗

Horizontal space misrepresentation in unilateral brain damage. I. Visual and proprioceptive-motor influences in left unilateral neglect.

Patients with unilateral neglect can misperceive horizontal distances in the contralesional space as being shorter than equivalent ipsilesional ones. We evaluated the visual and motor-proprioceptive components of space misrepresentation through a distance reproduction task performed both with and without visual guidance. Four groups of right brain damaged patients (neglect with hemianopia (N+H+), neglect with inferior quandrantanopia (N+Q+), neglect without hemianopia (N+H-) and patients without neglect or hemianopia (N-H-)) and one group of healthy controls (C) performed the line bisection task and reproduced horizontal distances either by setting the endpoints or by doubling the length of a line in the contralesional or ipsilesional space. The doubling length task was administered in three different conditions: (a) visuomotor (the patient draws the line in free vision); (b) visual (by sight the patient guides the examiner drawing the line); (c) proprioceptive-motor (the patient is blindfolded and manually inspects and extends the horizontal distance subtended by the line). Compared to C and N-H- patients, only N+H+ patients exhibited a significant ipsilesional shift in line bisection. N+H+ patients showed the most severe contralesional-overextension/ipsilesional-underextension asymmetry in the endpoint, visuomotor and visual line extension task. In the proprioceptive-motor condition no asymmetry was found and N+H- showed greater overextension on both sides of space. In N+H-, brain damage was mainly centered in central-frontal cortex and basal ganglia. These findings re-emphasize the relevance of damage to visual retinotopically organized representations of space in the genesis of horizontal space misrepresentation of neglect patients and suggest the possible association of a non-lateralized defective processing of proprioceptive-motor information with unilateral neglect.

Adult↗

Horizontal space misrepresentation in unilateral brain damage. II. Eye-head centered modulation of visual misrepresentation in hemianopia without neglect.

We used a visual distance reproduction task (endpoint task) to evaluate horizontal space representation in two left brain damaged (LBD) and three right brain damaged (RBD) patients with contralateral homonymous hemianopia and no neglect. All patients were examined in the chronic phase of the stroke and were aware of their visual field defect. Along with contralesional deviation in the line bisection task, all patients estimated size (Landmark task) and distances in the contralesional space as being longer than equivalent size and distances located in the ipsilesional space. Misreproduction of distances was abolished or reduced when the task was performed in the ipsilesional head-centred space with the head turned contralesionally. This finding points out that misrepresentation of horizontal space linked to hemianopia can be modulated by combined proprioceptive input from eye and neck muscles. The pattern of misrepresentation found in chronic hemianopic patients is opposite to the one described in chronic neglect patients with concomitant hemianopia. These different patterns of space misrepresentation are the likely consequence of the presence, in hemianopics, and the absence, in neglect patients with hemianopia, of compensatory strategies based on the non-retinotopic and multimodal coding of spatial positions falling in the retinotopically organised blind field.

Adult↗

Binocular vision and prehension in middle childhood.

Binocular cues have been shown previously to make an important contribution to the control of natural prehensile movements in adults [Visual Cognition 4 (1997) 113, Vision Research 32 (1992) 1513, Neuropsychologia 38 (2000) 1473]. The present study examined the role of binocular vision in the control of prehension in middle childhood. Fourteen children aged 5-6 years, and 16 children aged 10-11 years reached out and grasped different sized objects at different distances, in either binocular or monocular viewing conditions. In contrast to adult data, many of the principal kinematic indices of the children's reaches were unaffected by the removal of binocular information. The older children, like adults, spent an increased amount of time in the final approach to the object when only monocular information was available. However, both peak wrist velocities and peak grip apertures were unaffected by the removal of binocular information and continued to scale with object properties in the normal way. These results suggest that the use of binocular cues to control prehensile movements is not yet mature at the age of 10-11 years.

Child↗

Comparing extra-retinal information about distance and direction.

The idea that extra-retinal information about the orientation of the eyes could be used to judge an object's distance has a long history, and has been the issue of considerable debate throughout this century. We here show that the poor performance in comparison with judgements of direction has geometrical rather than physiological reasons, and discuss why previous studies have misled us into believing that information about distance is even poorer than the geometry predicts.

Convergence, Ocular↗

The use of an implicit standard for measuring discrimination thresholds.

We measured thresholds for comparing the separation between lines, using either the method of constant stimuli (MCS) or the method of single stimuli (MSS). In the MCS an explicit standard is presented on each trial, whereas in the MSS the standard is the mean of the set. The thresholds for the MSS procedure were nearly identical to those with the MCS procedure, whether or not feedback was used. A statistical model is presented showing how the threshold error estimated by MSS varies according to the number of past stimuli used by the observer to calculate the mean of the set. If the model is an accurate representation of human processing, our observers were averaging over the last 10-20 trials to estimate the implicit standard. Our results show that the explicit standard in the MCS procedure is generally superfluous. Provided that the test range is small, and that the observer is given some practice trials, thresholds measured with MSS procedure are just as precise as those measured with the traditional MCS procedure.

Differential Threshold↗

A physiologically-based explanation of disparity attraction and repulsion.

Westheimer and Levi [(1987) Vision Research, 27, 1361-1368] found that when a few isolated features are viewed foveally, the perceived depth of a feature depends not only on its own disparity but also on those of its neighbors. The nature of this interaction is a function of the lateral separation between the features: When the distance is small the features appear to attract each other in depth but the interaction becomes repulsive at larger distances. Here we introduce a two-dimensional extension of our recent stereo model based on the physiological studies of Ohzawa, DeAngelis and Freeman [(1990) Science, 249, 1037-1041] and demonstrate through analyses and simulations that these observations can be naturally explained without introducing ad hoc assumptions about the connectivity between disparity-tuned units. In particular, our model can explain the distance-dependent attraction/repulsion phenomena in both the vertical-line configuration used by Westheimer [(1986) Journal for Neurophysiology, 370, 619-629], and the horizontal-line-and-point configuration used by Westheimer and Levi. Thus, the psychophysically observed disparity interaction may be viewed as a direct consequence of the known physiological organization of the binocular receptive fields. We also find that the transition distance at which the disparity interaction between features changes from attraction to repulsion is largely determined by the preferred spatial frequency and orientation distributions of the cells used in the disparity computation. This result may explain the observed variations of the transition distance among different subjects in the psychophysical experiments. Finally, our model can also reproduce the observed effect on the perceived disparity when the disparity magnitude of the neighboring features is changed.

Computer Simulation↗

Contour interaction in amblyopia: scale selection.

It has been known for some time that visual acuity in amblyopia is higher for single letters than for letters in a row (termed crowding). Early work showed that this could not be accounted for on the basis of the destructive interaction of adjacent contours (termed contour interaction), which was shown to be, in resolution units, normal in amblyopia. We have re-examined this issue using a letter stimulus that is modulated about a mean light level. This allows an examination of the effects of contrast polarity and spatial filtering within the contour interaction paradigm. We show that the majority of strabismic amblyopes that we investigated exhibit an anomalous contour interaction that, in some cases, was dependent on the contrast polarity of the flanking stimuli. Furthermore, we show that while amblyopes do select the optimum scale of analysis for unflanked stimuli, they do not select the optimum scale of analysis for flanked stimuli. For reasons that may have to do with their poorer shape discrimination, they select a non-optimal scale to process flanked stimuli.

Adolescent↗

How vertical disparities assist judgements of distance.

The ratio of the vertical sizes of corresponding features in the two eyes' retinal images depends both on the associated object's distance and on its horizontal direction relative to the head (eccentricity). It is known that manipulations of vertical size ratio can affect perceived distance, size, depth and shape. We examined how observers use the vertical size ratio to determine the viewing distance. Do they use the horizontal gradient of vertical size ratio, or do they combine the vertical size ratio itself with the eccentricity at which it is found? Distance scaling (as measured by having subjects set an ellipsoid's size and shape to match a tennis ball) was no better when the judged object was 30 degrees to the right of the head (where vertical size ratios vary considerably with distance) than when it was located straight ahead. Distance scaling improved when vertical disparities were presented within larger visual fields, irrespective of where this was relative to the head. Our results support the proposal that subjects use the horizontal gradient of vertical size ratio to estimate the distance of an object that they are looking at.

Distance Perception↗

Binocular information about time to collision and time to passage.

It is well known that, when an object's horizontal relative disparity is changing appropriately, most observers report a compelling impression that the object is approaching and will collide with the observers at some future instant. Here I derive a new equation, namely TTC approximates (ddelta/dt)/(d(2)delta/dt(2)). This equation relates TTC to retinal image variables without involving a knowledge of the approaching object's distance or speed. In this respect the new equation is the binocular equivalent of the well-known equation for tau.

Automobile Driving↗

Judging distance from ocular convergence.

Subjects misjudge distances considerably when forced to rely on extra-retinal information. Nevertheless, they can reproducibly set a target to the same distance as a reference, or to double or half that distance, even when they have to look back and forth between them because they are prevented from seeing one when looking at the other. Our explanation for this apparent discrepancy is that people have access to reasonably accurate extra-retinal information on changes in ocular convergence, but can only use this information to judge distances if they had reliable information about the orientation of the eyes before the convergence changed.

Convergence, Ocular↗

Long range interactions between oriented texture elements.

Long range interactions between texture elements (short, oriented line segments) were examined. Specifically, we studied the influence of a background array of texture elements on the detectability of a target element (separated from the background by an intermediate textured region) using textures like those of Caputo (Vis. Res. 1996, 36, 2815-2826). We found that, in general, when the background elements were oriented orthogonally to the target element, detection of the target element was better than when the background elements had the same orientation as the target element. We discuss these interactions in terms of inhibitory and excitatory connections between orientation and spatial frequency selective linear filters (e.g. filters which mimic V1 simple cells) which would respond to the individual texture elements.

Choice Behavior↗

Perceived distance, shape and size.

If distance, shape and size are judged independently from the retinal and extra-retinal information at hand, different kinds of information can be expected to dominate each judgement, so that errors in one judgement need not be consistent with errors in other judgements. In order to evaluate how independent these three judgments are, we examined how adding information that improves one judgement influences the others. Subjects adjusted the size and the global shape of a computer-simulated ellipsoid to match a tennis ball. They then indicated manually where they judged the simulated ball to be. Adding information about distance improved the three judgements in a consistent manner, demonstrating that a considerable part of the errors in all three judgements were due to misestimating the distance. Adding information about shape that is independent of distance improved subjects' judgements of shape, but did not influence the set size or the manually indicated distance. Thus, subjects ignored conflicts between the cues when judging the shape, rather than using the conflicts to improve their estimate of the ellipsoid's distance. We conclude that the judgements are quite independent, in the sense that no attempt is made to attain consistency, but that they do rely on some common measures, such as that of distance.

Cues↗

Interaction between the perceived shape of two objects.

The difference between the way in which binocular disparity scales with viewing distance and the way in which motion parallax scales with viewing distance introduces a potential indirect cue for viewing distance: the viewing distance is the only distance at which disparity and motion specify the same depth. The present study examines whether this information is used. Two simulated ellipsoids were presented on a computer screen in complete darkness. The two ellipsoids were 6 degrees to the left and right of straight ahead. Subjects set the width and depth of each ellipsoid to match a tennis ball, and set the distance of the one on the right to half that of the one on the left. The distance of the left ellipsoid varied between trials. On half of the trials it was static. On the other half it was rotating up and down around its frontal horizontal axis. Rotating the left ellipsoid influenced its set depth: rotating ellipsoids were set to be much more spherical. There was no influence on the set depth of the other ellipsoid, or on the set width of either. The set distance of the right ellipsoid was also unaffected. We conclude that subjects do not combine binocular disparity and motion parallax to obtain more veridical information about viewing distance.

Distance Perception↗

Coarse-grained information dominates fine-grained information in judgments of time-to-contact from retinal flow.

To investigate the relative importance of fine- and coarse-grained structure in the analysis of retinal flow, subjects made estimates of time-to-contact from random dot kinematograms depicting movement towards a flat, sparsely textured surface. Individual display elements moved smoothly away from each other while expanding smoothly in size. By artificially manipulating the rate at which the individual elements expanded we showed that this cue has only a small effect upon performance. When individual elements were replaced by small clusters of dots, expansion of the clusters had a similarly small effect upon performance. However, estimates of time-to-contact were possible when a single expanding cluster was presented in isolation. We conclude that both types of information are available to the subject but that estimates of time-to-contact are based primarily on coarse-grained changes in the position of image elements and that fine-grained changes in element size or position play only a minor role.

Biomechanical Phenomena↗