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PubMedDate not supplied

Multi-center evaluation of a new wound dressing.

Ninety-two wounds were evaluated for at least three dressing changes each. The vast majority of the wounds were lightly exuding Stage II pressure ulcers and skin tears. This evaluation confirmed the hypothesis that the protective, conformable, and elastic properties of Flexzan, combined with its limited absorption capacity, high moisture vapor permeability and easy to use adhesive system, provided a dressing well suited to the management of the non- to lightly exuding wounds included. In addition, it was found to be a "superior" secondary dressing for alginate dressings on highly exuding wounds.

Adult↗
PubMed1993

Wound dressing.

Dressings are applications for wounds, burns, and ulcers. Dressings should be regarded as supportive of healing; they are desirable but not essential in an emergency. This article reviews measurement of wound healing and the functions of wound dressings. A variety of dressings and their respective advantages and disadvantages are discussed.

Adhesiveness↗
PubMed1998

[A new generation of dressings in the treatment of leg ulcers].

Current methods of topical treatment of leg ulcers are reviewed. Leg ulcers are chronic wounds in a trophically altered tissue that affects the healing capacity. Complete healing requires prolonged and rather expensive treatment and the patient is often disabled during this period. The conventional methods of treatment of leg ulcers, including various compresses, ointments, pastes and other topical drugs, that may possess a considerable sensitizing potential, are to an increasing extent replaced by updated therapy consisting in the use of a new generation of dressings. The latter include a number of materials that have been developed on the basis of recent knowledge of wound healing, such as hydrogels, hydrocolloids, xerogels, hydropolymer dressings, polyurethane foam sheets, alginate dressings, and non-adherent, non-woven cloth impregnated with silver and activated charcoal. The selection of the available materials must depend on the character and stage of the healing process. Each group of dressings exerts specific effects and none of them can recommended generally for the treatment of any types of ulceration. A brief survey of indications is given for each group to avoid their abuse.

Bandages↗
PubMed1991

Evolution of wound dressings and their effects on the healing process.

Over the last decade, there has been a rebirth of interest in wound healing research, partly due to advances in biotechnology leading to the feasibility of producing large quantities of pure, human growth factors thought to be important in the healing process and also due to the recognition that certain new dressing materials have a favorable impact in wound healing. This paper describes some of the newer dressing materials and discusses the basis for the biological effects of these products. As progress continues, it is likely that future approaches will combine the use of dressings with drugs or active agents selected to prevent or treat infection, start or stimulate the healing process, or control the production of scar tissue.

Biological Dressings↗
PubMed1998

The Hyphecan cap: a biological fingertip dressing.

An occlusive biological dressing, the Hyphecan cap, was evaluated in the management of full-thickness pulp defects of fingers and thumb in 20 consecutive patients. The cap was applied directly to the tip of the injured finger and allowed to separate gradually over the course of several weeks as new skin regenerated. This approach proved simple and effective in achieving a good functional and cosmetic result within a relatively short time, and eliminated the pain and discomfort associated with conventional dressing changes. We recommend the use of this dressing material in the Accident and Emergency department for the out-patient management of de-epithelializing fingertip injuries in both children and adults.

Adolescent↗
PubMed2002

Dressing selection in chronic wound management.

The concept of moist wound healing has been examined and gradually accepted by wound care clinicians during the last 40 years, and has led to the development of hundreds of dressings that support a moist wound environment. This article discusses the characteristics of an ideal dressing in an effort to assist clinicians in making appropriate dressing choices from common categories, including transparent films, hydrocolloids, foams, absorptive wound fillers, hydrogels, collagens, and gauzes. Reimbursement issues are also discussed.

Biological Dressings↗
PubMed1992

[Clinical experience with collagenous wound dressing in severe traumatic soft tissue injuries].

We treated 34 patients during 1987-1990 with a collagen wound dressing. Eleven patients had traumatic soft tissue defects, 10 patients had 3 degrees-grade open fractures, 7 patients had infected soft tissue wounds and 6 patients had deep 2 degrees and 3 degrees-degree burns. Our clinical experience confirmed the excellent clinical experimental results of collagen wound dressings. In all cases after 4 until 6 days of treatment good granulation and vascularisation of the wound bed was obtained, so that a skin transplant could be performed, which in all cases healed primarily. Moreover, the wound dressing had a good antibacterial effect and integrated actively in the wound healing process.

Adolescent↗
PubMed1987

The in vitro gaseous transmission of wound dressings.

The permeation properties of dressings to gases are important to the healing processes. It is necessary that dressings are permeable to water vapour, oxygen and carbon dioxide. A series of commercially available dressings have been assessed in vitro in respect of their permeability characteristics to these gases.

Bandages↗
PubMed2005

Biological evaluation of ChuangYuLing dressing-a multifunctional medicine carrying biomaterial.

The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China, the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing.

Animals↗
PubMed1976

Comparison of coarse mesh gauze with biologic dressings on granulating wounds.

Twenty patients with large area granulating wounds were selected for the study. On each patient, a small area of uniform appearance was divided into four subareas, and each subarea was randomly assigned treatment with a single 24 hour application of cadaver allograft, fresh porcine xenograft, formalinized xenograft, or "wet-to-dry" applications of coarse mesh gauze changed three times daily. At 24 hours, all four areas were uncovered. The subareas were ranked in terms of appearance on a best, second best, third best, and worst scale by experienced paramedical personnel who were not told which area received which treatment. Contact sponge quantitative microbiology was performed on each subarea before and after treatment on seventeen of the twenty patients. The results of these rankings suggest that coarse mesh gauze, changed three times daily, was significantly better at improving wound appearance than any of the biologic dressings. Among the biologic dressings, formalinized xenograft was significantly the worst. There was no significant difference between cadaver allograft and porcine xenograft. Analysis of quantitative cultures was limited by the problems of applying statistical methods to series of paired cultures in which initial values are quite different. Within the framework of such limitations and our 24 hour study, there was not significant change in surface colonization when either coarse mesh gauze or biologic dressings were used.

Adolescent↗
PubMedDate not supplied

A comparison of the use of polythene sheet and Jelonet as temporary dressings for excised wounds.

This paper reports our experience of the use of polythene sheet as a temporary dressing for excised wounds. A prospective randomised double-blind trial was conducted to see whether or not polythene dressing was less painful to remove than our traditional dressing of Jelonet. Polythene was found to be less painful (p less than 0.01). Other advantages of the use of polythene are presented.

Adolescent↗
PubMed1992

Evaluation of intra-alveolar chlorhexidine dressings after removal of impacted mandibular third molars.

Chlorhexidine gluconate (CHX) has been investigated for its possible benefit in the prevention of alveolar osteitis complicating third molar removal. In a double-blind, placebo-controlled clinical study, 70 randomly selected healthy patients were subjected to uncomplicated mandibular third molar removal followed by CHX-gelatin sponge and saline solution-gelatin sponge intra-alveolar dressings. Each patient was followed for 6 days for postoperative discomfort and complications, and scored accordingly. The results demonstrated that patients receiving 0.2% CHX intra-alveolar dressings exhibited a significant reduction in postoperative discomfort and complications when compared with saline solution-treated control sites (p less than 0.005). Further, this phenomenon was not found to be related to patient factors including age, sex, and race, nor did any correlation exist between treated or control sites, and surgical factors including performing surgeon, surgeon's dominant hand, time of surgery, surgical site, and difficulty of the removal. These findings warrant further studies concerning the apparent clinical benefit of postextraction intra-alveolar CHX dressings for the reduction of postoperative alveolar osteitis.

Adult↗
PubMed1996

Application of benzyl hyaluronate membranes as potential wound dressings: evaluation of water vapour and gas permeabilities.

Membranes of 75% and 100% benzyl hyaluronate esters (percentage of total carboxylate groups esterified) were prepared and their water vapour, oxygen and carbon dioxide transmission rates determined. The values of these properties were compared with the values obtained for several commercial wound dressings under the same conditions. The benzyl hyaluronate membranes showed water vapour transmission rates (2157-2327 gm-2 per day) comparable to those from commercial skin dressings (426-2047 gm-2 per day). In the dry state, the benzyl hyaluronate membranes showed lower oxygen and carbon dioxide transmission rates. Taking into account the biocompatibility of the hyaluronic acid esters, and the possibility that therapeutic agents could be incorporated into these membranes, the results indicate that the benzyl hyaluronate membranes have potential wound dressing applications.

Biocompatible Materials↗
PubMed1984

Experimental infection and hydrogel dressings.

The prolonged use of a hydrogel (polyacrylamide) dressing on circular 1 cm skin defects was tested in a rat experimental model. The rate of healing and changes in bacterial content following inoculation of 1 X 10(8) Staphylococcus aureus, Escherichia coli or Pseudomonas aeruginosa were measured. Wounds inoculated with Staph. aureus or E. coli prior to polyacrylamide occlusion did not have delayed wound contraction and healing and numbers of organisms were falling at 10 days. Wounds inoculated with Ps. aeruginosa showed a delay in healing with a large increase in organisms (greater than 1 X 10(10] after 10 days occlusion. Prolonged wound occlusion by hydrogel dressings may aid in healing by secondary intention but the presence or growth of pseudomonas indicates that frequent changes of dressings should be made.

Animals↗
PubMed1984

A comparison of the morbidity associated with occlusive and non-occlusive dressings applied to peripheral intravenous devices.

In a non-randomized controlled study of the effects of an occlusive polymer dressing on the morbidity associated with intravenous (iv) cannulation, it was found that the polymer dressing adversely affected the rate of cannula tip colonization, but that this could not be generally related to an increased risk of thrombophlebitis. A strong association was found between Staphylococcus aureus colonization and thrombophlebitis. It is proposed that the materials, method of manufacture and the use to which the cannula is put are more important in the genesis of the minor complications of iv cannulation than the type of dressing.

Catheters, Indwelling↗
PubMed1983

Stomahesive as a tracheostomy dressing.

Seven patients had occlusive stomahesive dressings placed on their tracheostomies. These patients were compared with four patients managed with standard tracheostomy care. Stomahesive was applied using a defined technique and all seven patients were followed until tracheostomy closure. The average duration of stomahesive care was 26 days and the dressings remained occlusive for an average of 4 days. Photographic evidence revealed that skin changes were less in patients treated with stomahesive dressings.

Humans↗
PubMed1987

The use of silver nitrate-incorporated amniotic membrane as a temporary dressing.

Human amniotic membrane is one of the most effective biological dressings used in burn treatment. Since 1978, we have been using human amniotic membrane incorporating 0.5 per cent silver nitrate. Studies in 96 patients using this method showed that the silver-incorporated membranes gave a better therapeutic effect than plain amniotic membranes. It was noted that 0.5 per cent silver nitrate incorporated into the membranes increased their manageability, provided easier application to the burned area and created a bactericidal effect, therefore reducing the risk of contamination and infection. One of the main advantages of wound coverage with amniotic membrane is that it does not appear to discourage re-epithelization, reduces fluid, protein, heat and energy loss, increases mobility and most important this may be the ideal wound cover next to the patient's own skin. Therefore, we highly recommend the use of 0.5 per cent silver nitrate-incorporated amniotic membrane, since it is readily available and freely obtainable, has low preparation and storage costs that make it an ideal dressing to use, especially in countries where economic factors prevent the purchase of other types of dressings.

Adolescent↗