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Illusory color mixing upon perceptual fading and filling-in does not result in 'forbidden colors'.

A retinally stabilized object readily undergoes perceptual fading. It is commonly believed that the color of the apparently vanished object is filled in with the color of the background because the features of the filled-in area are determined by features located outside the stabilized boundary. Crane, H. D., & Piantanida, T. P. (1983) (On seeing reddish green and yellowish blue. Science, 221, 1078-1080) reported that the colors that are perceived upon full or partial perceptual fading can be 'forbidden' in the sense that they violate color opponency theory. For example, they claimed that their subjects could perceive "reddish greens" and "yellowish blues." Here we use visual stimuli composed of spatially alternating stripes of two different colors to investigate the characteristics of color mixing during perceptual filling-in, and to determine whether 'forbidden colors' really occur. Our results show that (1) the filled-in color is not solely determined by the background color, but can be the mixture of the background and the foreground color; (2) apparent color mixing can occur even when the two colors are presented to different eyes, implying that color mixing during filling-in is in part a cortical phenomenon; and (3) perceived colors are not 'forbidden colors' at all, but rather intermediate colors.

Adult↗

Almost complete colour constancy achieved with full-field adaptation.

A successive asymmetric colour-matching task was used to study the changes in colour appearance of simulated Munsell samples. Colour shifts were induced with two Planckian illuminants, standard illuminant A (u'=0.256, v'=0.524) and illuminant S (u'=0.174, v'=0.392). Measurements were conducted with a 20 degrees field and a 120 degrees field. Adaptation period varied from 1 to 30s with the smaller field and from 1 to 60s with the larger field. Colour shifts were specified in terms of a modified Brunswik ratio (BR). Higher values of BR were associated with longer adaptation periods but only when the larger background was used. Supplementary experiments showed that the changes in colour appearance were related to a slight shift in the perceived colour of the background. The timing of the colour shifts are modelled in terms of cone opponent responses. High values of BR correspond to almost complete von Kries adaptation in all three cone types.

Adaptation, Ocular↗

The role of perceptual learning on modality-specific visual attentional effects.

Morrone et al. [Morrone, M. C., Denti, V., & Spinelli, D. (2002). Color and luminance contrasts attract independent attention. Current Biology, 12, 1134-1137] reported that the detrimental effect on contrast discrimination thresholds of performing a concomitant task is modality specific: performing a secondary luminance task has no effect on colour contrast thresholds, and vice versa. Here we confirm this result with a novel task involving learning of spatial position, and go on to show that it is not specific to the cardinal colour axes: secondary tasks with red-green stimuli impede performance on a blue-yellow task and vice versa. We further show that the attentional effect can be abolished with continued training over 2-4 training days (2-20 training sessions), and that the effect of learning is transferable to new target positions. Given the finding of transference, we discuss the possibility that V4 is a site of plasticity for both stimulus types, and that the separation is due to a luminance-colour separation within this cortical area.

Attention↗

Combining local and global contributions to perceived colour: an analysis of the variability in symmetric and asymmetric colour matching.

Are surfaces' colours judged from weighted averages of the light that they reflect to the eyes and the colour contrast at their borders? To find out we asked subjects to set the colour and luminance of test disks to match reference disks, on various backgrounds, and analysed the variability in their settings. Most of the variability between repeated settings was in luminance. The standard deviations in the set colour were smallest when the disk and background were the same colour, irrespective of the colour itself. Matches were equally precise for greenish or reddish disks on a grey background, as for grey disks on a greenish or reddish background. The precision was less dependent on the colour contrast at the disks' borders when the backgrounds were more complex and when there was a large luminance contrast at the disks' borders. Subjects were less precise when different colours surrounded the two disks. These findings are consistent with the perceived colour at any position being a weighted average of the local cone excitation ratio and the change in the cone excitation ratio at the borders of the surface in question. However, the involved weights must be variable and depend systematically on parameters such as the luminance contrast at the surface's borders and other chromatic contrasts within the scene.

Color Perception↗

A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration.

PURPOSE: To assess the effects of a single 100-mg dose of sildenafil citrate on visual function in men with early-stage age-related macular degeneration. DESIGN: Randomized double-blind placebo-controlled clinical trial. METHODS: Nine men (mean age 71 years, range 59-85 years) with early-stage (minimal visual impairment and large drusen in the macula) age-related macular degeneration and 20/40 or better-corrected visual acuity in at least one eye were prospectively randomized to receive either placebo or sildenafil citrate (Viagra; Pfizer Inc, New York, New York) 100 mg as a single oral dose. After 7-14 days, they received the alternate treatment. Subjects underwent visual acuity, Amsler grid, color discrimination (D15), traffic light, Humphrey perimetry, and photo-stress testing in each eye before and at specific intervals within 8 hours after dosing. RESULTS: Compared with placebo, no pattern of errors were evident in any visual function test following sildenafil administration. No statistically or clinically relevant changes from baseline were observed in visual acuity, Humphrey perimetry (corrected pattern standard deviation), D15 color discrimination, or photo-stress tests. No clinically relevant changes were observed in the Amsler grid or traffic light tests. Sildenafil treatment was associated with transient mild or moderate headache, flushing, and rhinitis. There were no visual adverse events spontaneously reported to the investigator. CONCLUSION: A single 100-mg dose of sildenafil was well tolerated and produced no acute visual effects or exacerbation of preexisting visual impairment in nine men with early-stage age-related macular degeneration.

3',5'-Cyclic-GMP Phosphodiesterases↗

Acquired color vision defects in retrobulbar neuritis.

We used the Farnsworth-Munsell 100 Hue Test to study the incidence of acquired color vision defects in 16 patients with unilateral and and seven patients with bilateral retrobulbar optic neuritis whose visual acuity had recovered to 6/12 (20/40) or better. We recorded the visual-evoked response to a pattern stimulus on the same day. All 30 affected eyes showed an excessive number of errors on Farnsworth-Munsell 100 Hue testing. The number of errors increased with greater residual optic nerve damage. One false-positive and two false-negative visual-evoked responses were found.

Adult↗

Ishihara color plates as a test for simultanagnosia.

PURPOSE: To alert ophthalmologists to the use of Ishihara color plates in the detection of simultanagnosia. METHODS: We examined seven patients referred for impaired vision. Evaluation included color plate testing with Ishihara color plates. RESULTS: All seven patients had simultanagnosia, with marked difficulty in identifying the numbers in Ishihara color plates despite adequate visual acuity and the ability to name all of the colors in the plates correctly. One of these patients was referred with the diagnosis of a cone dystrophy because of her poor performance on the Ishihara test. All of the patients had bilateral occipitoparietal damage or atrophy on magnetic resonance imaging. CONCLUSIONS: Ophthalmologists must be aware that a poor performance with Ishihara plates may not be attributable to an impairment of color vision but rather to occipitoparietal brain damage associated with simultanagnosia.

Agnosia↗

Psychophysical tests in X-linked retinitis pigmentosa carrier status.

Psychophysical tests were performed in 22 normal women and 17 X-linked carriers of retinitis pigmentosa. The tests consisted of luminance contrast sensitivity, grating at the fovea and broken annulus at the periphery, color contrast sensitivity, letters for the fovea and broken annulus for the periphery, along the three known confusion axes of protan, deutan and tritan observers. Statistical analysis of the data shows that there were significant differences between the carriers and age-similar normal subjects with all the tests. The most significant differences (P < 0.001) were found with the color contrast sensitivity at the periphery along the protanopic and deutanopic axes and the luminance contrast sensitivity at the periphery. The influence of the age is discussed.

Adolescent↗

Chromatic induction and the layout of colours within a complex scene.

A target's apparent colour is influenced by the colours in its surrounding. If the surrounding consists of a single coloured surface, the influence is a shift 'away' from the surface's colour. If the surface is more than 1 degrees from the target area the shift is very small. If there are many surfaces, then not only the average luminance and chromaticity of the surfaces matters, but also the chromatic variability. It is not yet clear whether it makes any difference where the chromatic variability is within the scene, so we constructed stimuli in which the chromatic variability was restricted to certain regions. We found that it made very little difference where the chromatic variability was located. The extent to which the average colour of nearby surfaces influences the apparent colour of the target seems to depend on the average chromatic variability of the whole scene.

Color Perception↗

Colour discrimination thresholds in Parkinson's disease: results obtained with a rapid computer-controlled colour vision test.

A dysfunction of dopaminergic retinal neurons is thought to occur in Parkinson's disease, manifesting itself in impaired performance on various visual discrimination tasks. We have investigated whether differences in colour discrimination could readily be detected between a normal group and a Parkinsonian group, using a computer-controlled test of colour vision. Although some individual Parkinsonian patients showed an abnormal elevation of colour discrimination thresholds, there was no significant difference between the normal group and the Parkinsonian group.

Age Factors↗

Dependence of color on context in a case of cortical color vision deficiency.

Color constancy depends on sensitivity to change in both illumination spectral properties and object position. We investigated this latter form of color constancy by asking a cerebral achromatopsic to name the colors of papers that were presented atop black, gray or white backgrounds under identical illumination. Comparison of color names across background conditions reveals poor constancy, characterized by a contrasting of foreground and background values that is not corrected by proper anchoring.

Brain Diseases↗

Colour vision in normal subjects tested by the colour arrangement test 'Roth 28-hue desaturated'.

The aim of the study was to obtain normal values for the colour-arrangement test, Roth 28-hue desaturated. In 146 healthy non-smokers colour vision was tested monocularly. The subjects were divided into four age groups: 0-19, 20-39, 40-59, and 60-79 years. The overall error score for all groups was 54 +/- 24 (median +/- mean absolute deviation). The values for the 20-39 year group were significantly lower than those for the other groups (Kruskal-Wallis: P < 0.0001 with subsequent multiple Mann-Whitney test). An increasing predominance of errors along the blue-yellow-axis was observed with increasing age. The error scores of normal subjects tested by the Roth 28-hue desaturated were comparable with those on the well-known Farnsworth-Munsell 100-hue (FM-100). Because the Roth 28-hue desaturated is shorter and simpler to administer, it is an alternative to the FM-100 in situations that need to assess colour discrimination and error axis quantitatively and quickly.

Adolescent↗

Color appearance: neutral surrounds and spatial contrast.

The experimental data in this paper show that chromatic bars presented in alternation with equiluminant neutral-appearing bars are seen as more saturated than the same chromaticity presented as a uniform rectangle. This effect was diminished but not eliminated when test and match stimuli were presented within a slightly dimmer neutral surround. The test stimulus was a 2 x 5 degrees rectangle with a 0.7 cpd square wave grating composed of alternating equiluminant chromatic test bars and neutral bars. Asymmetric matching was used to match the test bar appearance to a uniform 2 x 5 degrees comparison rectangle. Test and comparison stimuli were presented to separate eyes in a haploscope and appeared flanking a central fixation target. Data were collected with test and inducing stimuli on the cardinal axes of color space. Test bars separated by neutral bars appeared more saturated than the comparison rectangle for both the l- and s-axis directions. Manipulation of excitation on one cardinal axis did not affect the appearance matches made for the other cardinal axis.

Adult↗

Colour vision in gyrate atrophy.

A follow-up study of colour vision in two patients with gyrate atrophy was performed. Gyrate atrophy was diagnosed in the first patient at the age of 17 years. Her colour vision was first tested at the age of 25 years; at the follow-up examination 7 years later, she correctly interpreted the Standard Pseudoisochromatic Plates part 2, however, with one mistake due to lens opacity. In the Farnsworth-Munsell 100 hue test and in the Color Vision Meter 712 (CVM) anomaloscope, the results were within normal ranges. In the second patient, gyrate atrophy was diagnosed at the age of 4 years. At the ages of 4 and 5 years, he correctly interpreted the Ishihara, AO H-R-R, and Lanthony Tritan Album plates as well as the City University test. At the ages of 6, 7, and 8 years, he correctly interpreted the plate tests, the Farnsworth Panel D 15, and Lanthony's Desaturated Panel. The CVM anomaloscope results were normal.

Adult↗

Recent evolution of uniform trichromacy in a New World monkey.

Until recently, New World primates were found to have a single M/L photopigment gene on the X-chromosome. This arrangement limits males to dichromatic, or monochromatic color vision. Only females who were heterozygous for the M/L gene were trichromatic. Recently, an exception has been discovered. Male howler monkeys appear to have more than one M/L pigment gene, and both genders are uniformly trichromatic. We characterized promoter regions corresponding to two M/L pigment genes in howlers. Comparison of DNA sequences with those of humans and three species of New World primate suggest a recent and independent acquisition of a second M/L gene locus in the howler.

Animals↗

The oblique effect with colour defined motion throughout the visual field.

We assessed the extent of the oblique effect (OE) and the meridional orientation effect (MOE) for a chromatic motion task using red/green gratings throughout an 80 degrees visual field. Four different stimulus orientations were tested. Generally, sensitivity to chromatic motion decreased with increasing eccentricity regardless of the visual field meridian. Also, sensitivity was highest for horizontal or vertical gratings, thus supporting the presence of an OE rather than of a MOE. The strength of the OE varied between subjects, but was present from the fovea to 20 degrees of eccentricity. At 40 degrees of eccentricity, chromatic motion was always perceived but the grating orientation did not consistently influence chromatic motion sensitivity. The present study confirmed our previous results on chromatic motion sensitivity and isoluminance ratios throughout the visual field. In addition, our data show that the chromatic system can exhibit OEs at lower spatial frequencies than is observed for the achromatic system.

Analysis of Variance↗