Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Carcinosarcoma”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 829 records · Page 46Linked to original sources
PubMedDate not supplied

Intracapillary HbO2 saturation in tumor tissue of DS-carcinosarcoma during normoxia.

The measurements of the intravascular HbO2 saturation in tumor capillaries using the cryophotometric micromethod reveal that very low HbO2 saturation values predominate in malignant tumors. Under normoxic conditions only 8% of the measured values exceed 50% saturation. 53% of the intracapillary HbO2 saturation values are in the range of 0-10% HbO2 saturation. Great regional differences are seldom and can be found only in areas where a sufficient vascularization still exists. Taking into account the data of morphometric analysis of tumor vascularization and the parameters of respiratory gas exchange, the measured frequency distribution of HbO2 saturation values in tumor capillaries is simulated by means of different three-dimensional capillary structures; On the basis of these microcirculatory units, tissue pO2 values are computed in the intercapillary regions. As a result of these calculations it can be stated that the computed data derived from intracapillary HbO2 saturations are in sufficient agreement with pO2 values measured polarographically using gold- microelectrodes.

Animals↗
PubMed1983

Is renal cell (Grawitz) tumor a carcinosarcoma? Evidence from analysis of intermediate filament types.

The expression of intermediate filament type was determined in 13 renal cell (Grawitz) tumors (10 primary renal tumors and 3 lymph node metastases). All of the tumors except one lymph node metastasis contained cells expressing vimentin intermediate filaments, generally a marker of mesodermally-derived tissues and their tumors, the sarcomas. In addition, the 10 primary renal tumors and two lymph node metastases contained cells expressing keratin proteins. Using a monoclonal antibody to keratins, specific for glandular epithelial cells, it has been shown that some of the tumor cells resemble adenocarcinomas, at least in this respect. Double immunofluorescence labeling demonstrated that some of the vimentin-containing cells contained keratin while others did not. Only occasional cells were found to contain keratin but not vimentin. However, one of the lymph node metastases was positive only for vimentin. Thus Grawitz tumor cells express intermediate filament types which are generally biological markers of both sarcomatous and carcinomatous tumors.

Adenocarcinoma↗
PubMed2000

Biphasic sarcomatoid carcinoma (carcinosarcoma) of the renal pelvis with heterologous chondrogenic differentiation.

A case of a man with biphasic sarcomatoid carcinoma of the right kidney with chondrosarcomatous foci and with invasion of the pelvic mucosa and submucosa into the peripelvic adipose tissue is presented. In situ carcinoma of the urothelium of the right renal pelvis and proximal ureter was also noted. Comments on the nomenclature of malignant tumours with apparently mixed carcinomatous and sarcomatous phenotypes and a hypothesis on the histogenesis of these tumours are presented. Cytokeratin and p53 protein expression patterns, and the results of angiogenesis quantification are consistent with an epithelial-to-mesenchymal conversion induced by the stroma.

Aged↗