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PubMedDate not supplied

[Effect of incorporated ionizing radiation by cesium-137 on the state of free radical processes and the lipoprotein spectrum in rat blood].

In vivo experiments it was shown that the prolonged incorporated low levels radiation by 137Cs leads to changes in free-radical processes in blood and in lipoprotein exchange. It is considered that such changes could be very important for postradiation atherogenesis, as possible distant nonstochastic consequences of Chernobyl accident.

Animals↗
PubMedDate not supplied

[Lipid peroxidation in chicken digestive organs during postnatal ontogenesis under the effect of radioactive cesium].

The activity of superoxide dismutase, catalase and content of malondialdehyde, hidroperoxide lipids was studied in the tissues of liver, duodenum, pancreas of 1-day and 2-10 weeks age chicken. It was found, that tissues of 1-day chicken ages characterized by high contents of products of hydroperoxide lipids and activity of superoxide dismutase. The content of lipid peroxide oxidation in chicken tissues has an age peculiarity. The insertion of radioactive ceziy acts as an antioxidant and influences the lipid peroxide oxidation.

Animals↗
PubMedDate not supplied

[Effect of lithium and cesium ions on the effects of catecholamines and serotonin introduced into the rat hippocampus].

Local micro-injection of dophamine, norepinephrine and serotonin into the dorsal hippocampus of rats in doses of 5gamma does not affect the muscle tone and spontaneous motor activity of the animals, but lengthens the latent period of the conditioned avoidance reflex (CAR). When administered into the hippocampus in the same dose 15 minutes after injection of lithium chloride (1gamma equiv) dophamine inhibits stronger the CAR and noticeably stimulates the motor activity. At the same time, a preliminary injection of lithium cloride into the hippocampus does not change the action of norepinephrine and serotonin on the length of the latent CAR period, but, when used against the background of lithium chloride, norepinephrine depresses the motor activity.

Animals↗
PubMed1975

[Change in rabbit blood lymphocyte count after repeated extracorporeal irradiation with cesium 137. Comparison of heparin and acenocoumarol effects].

During repetitive extracorporeal irradiation, heparin treatment is responsible for a very high lymphocytic peak which does not last more than two days. This peak is not observed after using acenocoumarol as anticoagulant. That is why the degree of lymphocyte depletion after RECIB is to be interpreted in function of the anticoagulant used. This peak is temporary. No matter the anticoagulant used, lymphopenia is obtained after 15 days. The level of lymphocytic depletion is independent of the initial lymphocytosis.

Acenocoumarol↗
PubMedDate not supplied

Assessment of spatial variation of cesium-137 in small catchments.

Surface contamination by bomb-derived and Chernobyl-derived 137Cs has been subject to changes due to physical decay and lateral transport of contaminated soil particles, which have resulted in an on-going transfer of radionuclides from terrestrial ecosystems to surface water, river bed sediments, and flood plains. Knowledge of the different sources of spatial variation of 137Cs is particularly essential for estimating 137Cs transfer to fluvial systems and for successfully applying 137Cs as an environmental tracer in soil erosion studies. This study combined a straightforward sediment redistribution model and geostatistical interpolation of point samples of 137Cs activities in soil to distinguish the effects of sediment erosion and deposition from other sources of variation in 137Cs in the small Mochovce catchment in Slovakia. These other sources of variation could then be interpreted. Besides erosion and deposition processes, the initial pattern of 137Cs deposition, floodplain sedimentation, and short-range spatial variation were identified as the major sources of spatial variation of the 137Cs inventory.

Cesium Radioisotopes↗
PubMed1976

Cesium-129 myocardial scintigraphy to quantify myocardial infarction in dogs.

The sizes of surgically induced acute myocardial infarctions were quantified in a study of 28 dogs. Four projections (right and left anterior oblique, anterior, and left lateral) were obtained with 129Cs myocardial scintigraphy. Control images, taken before surgery, were compared with images taken 24-72 hr after coronary artery ligation. From postmortem examination the size of the infarct was determined and expressed as a percentage of the total left ventricle. On a standard diagram four independent observers marked the infarcted areas in each projection, expressed the severity of involvement in each area, and determined overall infarction size as a percentage of the total left ventricle. A nonlinear least-squares method was also employed to derive the size of the infarct, using the results from each observer's diagram. There were positive correlations between each observer's percentage estimate and the autopsy results. The overall accuracy of the least-squares method was similar to that of the individual observers. In this study, Observer 3 proved that acute myocardial infarcts can be quantified accurately from multiple scintigraphic projections of the myocardium, but the other three observers had difficulty in estimating infarct size. This difficulty probably resulted from the lack of well-validated criteria to aid the observer in determining the area of infarction, the severity of involvement within that area, or the total size of a myocardial infarct. Improvement in these estimates will require the development of definitive criteria, the use of optical scanners or computer processing, and combinations of radionuclides.

Animals↗
PubMed1976

Thyroid scanning with gallium-67 and cesium-131.

The roles of 131Cs and 67Ga in the evaluation of solitary thyroid nodules were investigated. Radionuclide scans were performed with 67Ga and 131I in 27 patients and with 131Cs and 131I in 43 patients. Gallium-67 detected only two of eight malignant nonfunctioning nodules and 131Cs detected one of three such nodules. The contribution of 131Cs and 67Ga to the preoperative identification of malignant thyroid lesions is of doubtful value.

Adenocarcinoma↗
PubMed1992

[Insight into the mechanism of torsade de pointes (TDP) induced by cesium chloride].

Standard intracellular potential recording technique was used in isolated guinea pig ventricular muscle and monophasic action potential (MAP) recording technique was performed on both the epicardium and endocardium of dog hearts in vivo. The results showed that CsCl lengthened action potential durations of ventricular muscle as well as QT intervals of dog hearts. The incidence of early after depolarization (EAD) induction was 71.4%. Ventricular tachycardia induced by CsCl manifested as typical TdP in 44.4% with EAD shown on epicardial MAP recording. This suggested that EAD and triggered activity might be an important mechanism of TdP. As verapamil could depress the induction of EAD, we believe that Ca++ inward currents was responsible for the induction of EAD and TdP by CsCl.

Action Potentials↗