Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “THIGH”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 811 records · Page 45Linked to original sources

Metastatic choriocarcinoma in a middle-aged man presenting as a right thigh mass with venous thrombosis: a case report.

Choriocarcinoma is a highly aggressive beta-subunit of human chorionic gonadotropin (betaHCG)-producing germ cell tumor. In men, it is a rare neoplasm and can arise in the testes or in various extragonadal locations such as the retroperitoneum, mediastinum, and pineal body. We present a highly unusual case of a middle-aged man with primary metastatic betaHCG-producing choriocarcinoma of the right thigh along with right lower-extremity venous thrombosis. We comment on prognostic variables as well as discuss several theories to account for the unusual location of his choriocarcinoma.

Choriocarcinoma↗

Hepatitis B vaccine in infants: a randomized controlled trial comparing gluteal versus anterolateral thigh muscle administration.

A significantly diminished antibody response to hepatitis B vaccine has been demonstrated in adults when the buttock is used as the injection site. However, in Brazil, the buttock continues to be recommended as site of injection for intramuscular administration of vaccines in infants. In this age group, there are no controlled studies evaluating the immunogenicity of the hepatitis B vaccine when administered at this site. In the present study, 258 infants were randomized to receive the hepatitis B vaccine either in the buttock (n = 123) or in the anterolateral thigh muscle (n = 135). The immunization schedule consisted of three doses of hepatitis B vaccine (Engerix Bregister mark or target, 10 microg) at 2, 4 and 9 months of age. There were no significant differences in the proportion of seroconversion (99.3% x 99.2%), or in the geometric mean titer of ELISA anti-HBs (1,862.1 x 1,229.0 mIU/mL) between the two groups. This study demonstrates that a satisfactory serological response can be obtained when the hepatitis B vaccine is administered intramuscularly into the buttock.

Buttocks↗

Subdural empyema caused by hematogenous dissemination from an abscess in thigh to a preexisting chronic subdural hematoma--case report.

A 63-year-old male with a preexisting chronic subdural hematoma presented with progressive confusion and left hemiparesis as well as high fever. Subdural empyema was strongly suspected. At surgery, the empyema was encapsulated by definite inner and outer membranes. Cultures isolated from the subdural fluid and from an abscess of his left thigh yielded methicillin-resistant Staphylococcus aureus. A pulsed-field gel electrophoresis showed these two strains were genetically identical. Hematogenous infection of a preexisting subdural hematoma is an extremely rare cause of subdural empyema.

Abscess↗

Computed tomography in the evaluation of sarcomatous tumors of the thigh.

CT examination of a soft tissue mass in the lower extremity adds substantially to a more precise preoperative histologic diagnosis and anatomic localization of the lesion. An appreciation of the normal cross-sectional anatomy of this region is essential for adequate evaluation of the information provided by the CT scan. Four patients with sarcomatous tumors involving the soft tissues of the thigh are described and the diagnostic information provided by CT is discussed. In two of these cases anatomic cross sections are correlated with the CT scan.

Adolescent↗

Differential diagnosis in physical therapy evaluation of thigh pain in an adolescent boy.

Slipped capital femoral epiphysis (SCFE) is a condition of the adolescent hip in which the femoral head displaces relative to the femoral neck. This disorder is characterized by a synovitis of the hip joint or a mechanical limitation of motion with pain referred to the thigh or knee. The case described in this report is typical of an adolescent with SCFE. A brief review of epidemiology, etiology, clinical presentation, and treatment is presented to facilitate the physical therapist's knowledge of this condition and its proper management. Delay in diagnosis and treatment of SCFE may result in progression of the slip and chronic disability from osteoarthritis. It is imperative, therefore, that a patient suspected of having this condition be promptly referred to an orthopaedic surgeon for radiographic evaluation.

Adolescent↗

Melanotic neuroectodermal tumor of infancy occurring in the left thigh of a 6-month-old female infant.

We report an exceptional case of melanotic neuroectodermal tumor of infancy (MNTI) occurring in the soft tissue of the left thigh of a 6-month-old female infant. The tumor consisted mainly of small round cells (neuroblasts) arranged in cords and nests that were separated by broad fibrovascular areas. In addition, there were a few medium-sized tumor cells containing melanin pigment (melanocytic cells) that in electron microscopy contained melanosomes as well as tonofilaments. Both tumor cell types immunostained for neuron-specific enolase (NSE) and vimentin, and the melanocytic cells reacted additionally with the antikeratin antibody KL1. Within the tumor stroma, neurofilament- and S-100-protein-positive neural cells and vimentin- and desmin-positive myofibroblasts were seen. Although dense-core granules were demonstrated ultrastructurally in some neuroblasts, no immunostaining for chromogranin A, Leu-7, serotonin, or regulatory peptides was found. MNTI located in an extremity can be confused with malignant small round and blue cell tumors of childhood. The distinction between MNTI and these tumors is of clinical significance because MNTI, in most cases, is a benign tumor that, in contrast to the latter, can be cured by complete excision. The presence of a biphasic cell population with neuroblasts and melanocytic cells must be considered the main diagnostic feature of MNTI.

Female↗

Effects of alignment variables on thigh axial torque during swing phase in AK amputee gait.

It is suggested that a major source of discomfort for above-knee amputees during the swing phase of walking, is the thigh axial torque (TAT) transferred at the stump--socket interface. The relation between TAT and variations in its six relevant alignment adjustments, has been investigated. A computerized routine has been established which indicates optimum choice of alignment setting, based on minimal TAT peaks. Feasibility for attenuating swing phase TAT has been demonstrated in three simulated patterns of amputee gait. As a conclusion, it is suggested that a useful clinical tool could be based on the presented alignment optimization procedure and may be expanded to include other factors associated with swing and stance phase comfort and performance.

Amputation, Surgical↗

Function after removal of various hip and thigh muscles for extirpation of tumors.

Forty-six patients who had undergone excision of one or more well defined hip and/or thigh muscles because of a soft-tissue tumor or a tumoriform lesion were investigated with respect to the function of the operated limb and the isometric and isokinetic strength of the affected motion or motions, relative to the non-operated side (percentage). Hip flexion: Loss of the iliopsoas caused slight impairment of function. The flexion strength decreased with increasing flexion of the hip joint. Loss of the rectus femoris reduced the isometric strength by 37 and the isokinetic strength by 17 per cent. Hip abduction: The strength reduction was only about 50 per cent and the impairment of function only slight or moderate even in patients with extensive loss of abductor muscles. Hip adduction: Removal of all three prime adductors (longus, brevis, magnus) caused a strength reduction of about 70 per cent but the impairment of function was only slight or moderate. Hip extension: Loss of the gluteus maximus caused only a small strength reduction and no impairment or only slight impairment of function. Significant strength reduction was only seen when all hamstrings had been removed. Knee extension: Loss of one, two, and three of the quadriceps muscles reduced the isometric strength by 22, 33, and 55 per cent, respectively. The isokinetic strength was reduced somewhat more. The strength reduction usually had to exceed 50 per cent to cause more than slight impairment of function. Knee flexion: Loss of the semitendinosus, the biceps femoris, and all the hamstrings reduced the isometric strength by 24, 28, and 67 per cent, respectively. The isokinetic strength was reduced somewhat less. Loss of one of the hamstrings usually caused no impairment of function whereas loss of all three resulted in moderate impairment of function.

Adolescent↗

Scrotum-like protrusion of lipoma arising from the proximal thigh--report of two cases.

We report two cases of large lipomas arising from the proximal thigh with an extremely uncommon shape. The tumors were elastic soft and movable. MRI examination revealed both tumors with high signal intensity as fatty tissue on both T1 and T2-weighted images. Needle biopsy of the specimens revealed lipoma. Marginal excision was carried out for both cases because of the patients' discomfort. No recurrence was found three and five years after surgery, respectively.

Humans↗

Anterolateral thigh fasciocutaneous flap for simultaneous reconstruction of refractory scalp and dural defects. Report of two cases.

Infected full-thickness defects of the calvaria including the scalp, cranial bone, and dura mater, are often refractory to treatment and pose a difficult and urgent therapeutic problem for reconstructive surgeons. The authors report two cases in which successful reconstruction was achieved in one stage by using an anterolateral thigh fasciocutaneous flap. The well-vascularized fascia components were used to repair the infected dural defects. The skin flaps were used for coverage reconstruction.

Adult↗

Intermuscular lipomas of the thigh region in dogs: 11 cases.

Ten dogs with intermuscular lipomas in the thigh region were treated by surgical resection. The masses were located predominantly between the semitendinosus and semimembranosus muscles and involved the full length of the femur. These lipomas were not infiltrative but located deep between the fascial planes of the associated muscles. These tumors can appear similar to soft-tissue sarcomas in this location, but they can be differentiated by cytology and histology. Differentiation from an infiltrative lipoma is predominantly determined at the time of surgery. No tumors recurred in the median follow-up period of 17 months.

Animals↗

Appendicitis presenting as a swollen thigh.

A case of acute appendicitis presenting as an abscess in the thigh with associated gas is described. The tracking of the pus down the psoas muscle is stressed, and its association with the psoas sign is noted.

Abscess↗

Anatomical basis for congenital deformities of the lower extremities. Part I. The hip and thigh.

Congenital deformities frequently produce problems not always discernible at birth. Often, a period of time is required for the development of signs and symptoms. The present discussion presents the intrauterine anatomy of a midterm fetus relative to conditions of the hip and thigh. Cryomicrotomy is used in this study to present the best anatomical evidence of the morphology involved.

Abnormalities, Drug-Induced↗

Birthweight prediction by three-dimensional ultrasonographic volumes of the fetal thigh and abdomen.

Our validation study examined a three-dimensional ultrasonographic phantom that contained irregularly shaped volume targets ranging from 0.5 to 76.1 milliliters. Four different examiners made blinded measurements from volume datasets that were acquired by 4 and 7 MHz transducers. Birthweight predictions using abdominal and thigh volumes from 18 term fetuses also were compared with two-dimensional ultrasonographic methods. In vitro volume measurements were accurate, precise, and repeatable despite a small systematic overestimation with increasing object size. Mean systematic error and precision for birthweight predictions by three-dimensional ultrasonography (-0.03% +/- 6.1%) were not significantly different from those by two-dimensional ultrasonography (-0.60% +/- 8.8%). Conventional prediction methods yielded three birthweights with greater than 15% error. By comparison, except for one infant whose birthweight indicated an 11% error, all predictions based on fetal volume parameters were within 10% of true values. Accurate birthweight predictions by fetal volume parameters appear to be technically feasible at term gestation although their practical clinical application requires further investigation. Birthweight predictions in this manner may allow remote consultants to evaluate the fetus over wide-area computer networks despite the physical absence of the patient.

Abdomen↗

Thigh neuralgia as a symptom of obturator hernia.

A material of 8 patients with obturator hernias is presented. In 7 of the patients a neuralgic pain in the thigh was the main symptom and a hyperesthesia in the cutaneous segment of the obturator nerve was also common. A recognition and an early operation of this condition is important, since the mortality is high when an intestinal obstruction has complicated the disease.

Adult↗

The hemithigh microvascular transfer (combined anterolateral thigh flap and tensor fasciae latae flap) for a full thickness abdominal wall reconstruction: a case report.

In large, full thickness upper abdominal wall defects a free microvascular tissue transfer is the only option which will enable reconstruction of the structural integrity of the abdominal wall as well as give a good aesthetic appearance. We present a case in which such a defect was reconstructed by a 29 x 19 cm hemithigh free flap, combining the adjacent vascular territories of the anterolateral thigh flap and the tensor fasciae latae flap based on the lateral circumflex femoral artery.

Abdominal Muscles↗

[Acute compartment syndrome in the thigh: 3 cases].

We report three cases of compartment syndrome in the thigh related to drug intoxications. Compartment syndrome is an uncommon condition often diagnosed late as it may occur in unconscious patients. The typical clinical presentation begins with pain of the lower limb refractory to major antagesics. The condition then progresses with sensoromotor involvement of the sciatic nerve. Rapid onset of acute renal failure in the setting of a crush syndrome may be life-threatening with a long-term risk of major sensoromotor sequelae. Surgical treatment with aponeurotomy is required rapidly to limit sequelae.

Acute Kidney Injury↗

[A case of metachronous, multifocal development of liposarcoma in the back of left thigh, the left subclavicular region and the right perirenal tissue].

A 46-year-old woman had received surgery to remove a mass arising from the back of the left thigh 13 years before and on the left subclavicular region 3 years before. Histological diagnosis of both masses was myxoid type liposarcoma. She was admitted to our hospital because of right abdominal pain. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) revealed the presence of a large retroperitoneal tumor. The removed specimen weighed 1,450 g and measured 24 x 13 x 9 cm in size. Histological diagnosis was myxoid type liposarcoma. She has been free of any recurrence for 4 months postoperatively without adjuvant therapy.

Clavicle↗