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At least 811 records · Page 45Linked to original sources
PubMed1979

[Lumbar portion of the human spinal canal at different age periods].

The investigation was performed in 253 lumbosacral parts of the spinal column in fetuses, children and adult men in order to study age dynamics of the vertebral canal both at the level of the vertebra and at the level of the intervertebral disks. For the first time reliable data were obtained on dimentions of sagittal and frontal diameters of the canal at the lumbar level in practically healthy persons of different age. "Vertical comparison" of mean values of these parameters gave information on the character of spatial reaction of the canal dimentions and its form at various levels and demonstrated age peculiarities of these relations. In persons at the age of 22-74 years in vertibral segments of the lumbar part of the spinal column certain degenerative-destructive processes were revealed; they could affect the size and form of the canal. The rate, level and degree of these processes were demonstrated to vary in different age periods.

Adolescent↗
PubMed1991

Baricity and the distribution of lidocaine in a spinal canal model.

The role of the baricity of local anaesthetic solutions in determining the distribution of local anaesthetics injected into the subarachnoid space (and hence the level of anaesthesia) has been challenged. A recent study found no difference in the extent of cephalad spread of hyperbaric and isobaric solutions and concluded that density had no effect on the spread of local anesthetics. The present study, to determine the validity of this conclusion, utilized a spinal model filled with a "cerebrospinal fluid equivalent." Following the injection of hyperbaric lidocaine, the local anaesthetic was most concentrated at the lower end of the column, whereas following the injection of isobaric solution the local anaesthetic was most concentrated around the site of injection. Therefore, baricity is an important determinant of local anaesthetic distribution in the subarachnoid space.

Atmospheric Pressure↗
PubMed1993

Compromise of the spinal canal in Proteus syndrome.

We report on 2 children with spinal stenosis and neurologic sequelae. They illustrate the 2 ways in which spinal compromise may develop in Proteus syndrome--vertebral anomalies or tumor infiltration. In one patient, spinal stenosis resulted from an angular kyphoscoliosis. In the other, cord compression resulted from infiltration of a paraspinal, intrathoracic angiolipoma.

Angiolipoma↗
PubMed2003

Pressure aberrations inside the spinal canal during rear-end impact.

Minor soft tissue injuries of the cervical spine increasingly pose problems in public health. Such injuries are conveyed particularly often in rear-end automobile collisions at low impact speeds and it has been established that they may be associated with long-term impairment. As a possible cause for this type of injury it has been hypothesized that pressure pulses induced in cervical fluid compartments during the impact could damage the membrane of spinal nerve cells. To date, animal as well as cadaver experiments performed support this hypothesis. A theoretical analysis has been undertaken in order to investigate the pressure and flow pulse emerging in a cervical fluid compartment under conditions representing rear-end impacts with a Dv of 15 km/h. Using the finite element (FE) method, a three-dimensional model of the cervical spine was developed. The model consists of eight vertebrae (C1-T1), the intervertebral discs, the intervertebral joints, all the major ligaments, most of the neck muscles and the head. Additionally, a typical venous blood vessel was included. To determine the pressure behaviour inside the blood vessel, fluid-structure interaction was taken into account. For the time interval including the development of the S-shape, the pressure pulses were calculated and found to be in qualitative agreement with the reported measurements. The shear stresses acting on the vessel wall can be determined from the associated flow pulses. An extrapolation of the results into the interstitial space where nerve cells are located at this stage does not allow assessment of whether a damage threshold may be reached.

Accidents, Traffic↗