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Two cases of atypical membranous aplasia cutis with hair collar sign: one with dermal melanocytosis, and the other with naevus flammeus.

We report two atypical cases of membranous aplasia cutis surrounded by a rim of hairs, one case associated with dense dermal melanocytosis and the other with naevus flammeus, with characteristic clinical features. A rim of hypertrichosis, 'hair collar' sign, is proposed to have a close association with neuroectodermal defects. A failure of the normal closure of the cranial neural tube might have affected foetal skin development, including melanoblast migration and capillary network formation. The changes in the present cases, as well as the hair collar sign may suggest a complex hamartomatous nature of membranous aplasia cutis.

Ectodermal Dysplasia↗

A case of eruptive milia.

A 68-year-old woman presented with a 10-year history of multiple milia on her scalp. Spontaneous eruptive milia are uncommon and the term describes cases that are more extensive in number and distribution than would be expected in primary milia.

Aged↗

Dandruff-associated smouldering alopecia: a chronobiological assessment over 5 years.

BACKGROUND: In some individuals, dandruff may be recurrent and even chronic. This represents a difficult-to-treat condition. Excessive hair shedding and diffuse alopecia may develop. OBJECTIVES: To evaluate the chronobiological aspects of dandruff, hair shedding and alopecia. METHODS: This study was performed in eight men suffering from such a scalp condition. They were examined 40 times at regular intervals for five consecutive years. Hair-density assessments and trichograms were performed at least twice per trimester on the parietal region of the scalp, corresponding to an area where dandruff was present. RESULTS: A positive correlation was found between the percentage of telogen hairs and dandruff severity as assessed by the squamometry index. Bimodal yearly biorhythms were found for dandruff severity, telogen counts and hair loss between two consecutive visits. The chronobiological fluctuations were prominent in some study participants, but remained inconspicuous in others. The biorhythms were almost synchronized in all participants, showing variations over the year. CONCLUSIONS: The biorhythms on the hair cycle in dandruff are not fundamentally different from those previously reported in subjects without dandruff. The periodicity may be an intrinsic feature of human skin.

Adult↗

Hyphal production by Pityrosporum ovale.

Pityrosporum ovale with abundant hyphae was found in 8 patients with lesions of the scalp and glabrous skin. It is thought that P. ovale in its mycelial form can produce lesions on seborrheic areas of the skin that probably represent a clinical form of tinea versicolor.

Adolescent↗

Dermatophytic infection of the scalp in the region of Butare (Rwanda).

We examined samples of hairs taken from 60 children presenting with the clinical picture of tinea capitis. In 53 cases, direct microscopic examination showed either ectothrix or endothrix parasitism, and we were able to grow the causative dermatophyte. We had 34 strains of Trichophyton violaceum, 19 of Microsporom langeroni, and two of Trichophyton verrucosum. The latter is found for the first time in this region to be a cause of ringworm in humans.

Adolescent↗

A comparison of miconazole nitrate and selenium disulfide as anti-dandruff agents.

The anti-dandruff efficacy of two shampoos containing 2% miconazole nitrate and 2.5% selenium disulfide was compared in 15 subjects and eight subjects, respectively. The antifungal drug, miconazole nitrate, was found to possess anti-dandruff activity similar to selenium sulfide, a cytostatic compound. For evaluation, techniques of clinical grading and the corneocyte count were used and the latter was found inaccurate. Instead, clinical assessment by grading the severity, supplemented by cytodiagnosis by smear examination was found more helpful. The latter helps to evaluate both the altered pathophysiologic and microbial factors operating in a given case of dandruff, which is a symptom complex brought about by multiple etiologic factors.

Adolescent↗