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Segmental rigidity and spinal myoclonus as a paraneoplastic syndrome.

A 68 year old woman is described with persisting muscular rigidity of the left lower leg together with transient myoclonic jerking in the left quadriceps muscle. Six weeks after onset a small cell carcinoma of the lung became manifest. With radiotherapy and chemotherapy complete remission was achieved. Segmental muscular spasm improved at the same time. Necropsy revealed loss and degeneration of alpha-motor neuron cells at one side of the anterior horn of the lumbar enlargement. This case may represent another manifestation of paraneoplastic subacute motor neuronopathy.

Aged↗

[Methods for recording and quantitative measurement of rigidity and spasticity (author's transl)].

First pathophysiological aspects of rigidity and spasticity are described with special regard to the possibilities of errors during the measurement of muscle tone in man. The following methods are explained and discussed: Psychometric techniques, physical analysis of movements (kinesiology, photobadismography, kinetometry), pendulousness tests, investigations of reflexes (T-reflex, H-reflex, H/M-ratio), electromyographic methods (after-activity, silent period, unloading-reflex, stretch-reflex, release-phaenomen), and torque measurements. In the main we discussed these techniques with the view-point of diagnosis and drug effects. Furthermore we expressed our opinion on the relevance of the different methods. Last the most important sources of errors are tabulated.

Electromyography↗