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An argument for the use of total side frequencies of bilateral nonmetric skeletal traits in population distance analysis: the regression of symmetry on incidence.

In population studies based on frequencies of bilateral nonmetric skeletal traits, the choice between sampling by individuals or by sides should depend less on the exigencies imposed by fragmentary remains than on fundamental assumptions about the biological meaning of symmetry/asymmetry. Though the latter has been interpreted in various ways, little attention has focused on the possibility that bilateral correlation is meaningful in quantifying genetic liability for a trait. Analysis of two independent mandibular features, mylohyoid bridge and suppressed third molar, in Indian and Eskimo population samples (total N congruent to 1,200) reveals a statistically significant pattern of increasing bilateral occurrence with increasing population incidence. This pattern is consistent with the theory that liability for a "quasi-continuous" variant is normally distributed with constant increment between thresholds on an underlying scale. According to theory, phenotypes with more pronounced expression (bilateral occurrence) have greater genetic potential than those with less pronounced expression (unilateral occurrence). Therefore, scoring traits in total left and right sides, by giving greater weight to bilaterally affected individuals, may provide a better estimate of the liability for the trait in the population. Viewed in a theoretical context broader than that of the sampling debate, this pattern of positive regression of symmetry on incidence means that prevalence of unilateral occurrence probably cannot be used to assess the relative strength of genetic versus nongenetic control of threshold variants.

Age Factors↗

Form and patterning of anterior tooth wear among aboriginal human groups.

Form and severity of dental attrition was assessed in aboriginal human groups including hunter-gatherers (Eskimos, Australians) and those with dependence to a varying degree on food production (Southwest U.S. and Ohio American Indians). Wear on anterior teeth was both relatively and absolutely greater in the hunter-gatherers, as indicated by comparisons of wear on anterior and posterior teeth which come into occlusion at roughly the same time. Distinct differences in form of anterior wear were also apparent: The hunter-gatherers exhibited steadily increasing incidences of labially rounded wear with greater functional age, while the food-producing groups showed little or no rounding but instead high frequencies of heavily cupped wear (especially in those with premature loss of posterior teeth). These differences were attributed to nonmasticatory utilization of the front teeth in hunter-gatherers and to employment of the anterior teeth in masticatory (grinding) activities necessitated by large-scale molar loss in food producers.

Age Factors↗

Bone mineral-osteon analysis of Yupik-Inupiaq skeletons.

Living adult Eskimos from St. Lawrence Island, North Alaska, and Canada undergo an earlier and more rapid rate of age-related bone mineral loss compared to U.S. whites. Further, it has been shown that Eskimos and Indians differ in patterns of osteon remodeling at the Haversian envelope. Femoral bone cores from adult Eskimos skeletons from St. Lawrence Island (n = 53), Kodiak Island (n = 92), Baffin Island (n = 44), and Southampton Island (n = 69) were analyzed and the results compared with those obtained from cores from U.S. whites (n = 144). Cortical thickness, bone mineral content of cores, cortical bone density, secondary osteon and Haversian canal number and area were quantified for each core. Ages at death were estimated by histological methods and compared with the ages at death estimated by morphological methods for the Eskimo skeletons. Known ages at death were compared with histologically estimated ages at death for the U.S. white series. St. Lawrence Island and Kodiak Island (Yupik speakers) Eskimo cortical thickness values were significantly (P less than .05) greater than Baffin Island and Southampton Island (Inupiaq speakers) Eskimos cortical thickness values but less than the cortical thickness values for U.S. whites. The bone mineral content of the Southampton Eskimos femoral cores was the lowest found in this study. Histological analysis of the femoral bone sections showed that Eskimos contain more osteons per unit area than U.S. whites. No differences in osteon size were noted between the two populations. Differences in patterns of osteon remodeling between Eskimos and whites were inferred. Age at death estimation by histological methods in Eskimos using U.S. white regression equations yielded age estimates in poor agreement with those obtained by morphological methods.

Age Determination by Skeleton↗

Reindeer Chukchi and Siberian Eskimos: studies on blood groups, serum proteins, and red cell enzymes with regard to genetic heterogeneity.

Phenotype and allelic frequencies for ABO, MNSs, P, Rh, Kell, Duffy, and Diego blood groups, as well as for transferrins (Tf), haptoglobins (Hp), phosphoglucomutase 1 (PGM1), adenylate kinase (AK), 6-phosphogluconate dehydrogenase (PGD), and acid phosphatase (AcP) are described in 9-10 adjoining populations of Reindeer Chukchi. Additionally, one of three presently existing territorial subgroups of Siberian Eskimos was studied. The total sample size ranges from 931 to 1,066 in Chukchi, and from 99 to 102 in Eskimos, depending on the genetic system studied. Substantially reduced samples for Kidd and ABO secretion were investigated solely in the Reindeer Chukchi. Significant heterogeneity of allelic frequencies has been observed among Chukchi populations (X(2)124 = 378.47, P less than 0.001). Summed genetic heterogeneity between Reindeer Chukchi and Siberian Eskimos was also found to be highly significant (X(2)14 = 186.54, P less than 0.001). Both groups can be readily discriminated with only four outliers: Ns, P1, R1, and pa. Random genetic drift is suggested to be responsible for a large proportion of heterogeneity of allelic frequencies at the MNSs, P, and Rh blood-group system sites both among the Chukchi and Eskimos. Conversely, stabilizing selection is assumed as the principal agent maintaining homogeneous allelic frequencies at the AcP locus within the Chukchi subdivisions, whereas disruptive selection may be considered as a major factor leading to different Pa frequencies between Chukchi and Eskimos.

Arctic Regions↗

Population structure of Alaskan and Siberian indigenous communities.

Genetic data consisting of 14 red cell antigen groups and 11 serum and erythrocytic protein marker systems from four Eskimo populations of the Norton Sound area of Alaska are reported. The population structure of these four groups in analyzed both separately and within the larger context by comparison to 15 other circumpolar groups. These analyses reveal a good fit between genetic structure, geographic distribution, linguistic affiliation, and the ethnohistory of the region.

Alaska↗

The St. Lawrence Island Eskimos: genetic variation and genetic distance.

The Eskimos of St. Lawrence Island have been typed for genetic variation at 44 discrete genetic loci. Three private polymorphisms, at the 2,3-diphosphoglycerate mutase, peptidase B, and purine nucleoside phosphorylase loci, have been observed, which may be useful in future studies of genetic relationships between Eskimos and other circumpolar populations. Genetic distance analysis reveals a close relationship between the St. Lawrence Island Eskimos and other Eskimo populations and that the Eskimo populations form a distinct cluster from Amerindian populations. The St. Lawrence Island Eskimos appear to be more similar to Asiatic Eskimos than to other groups. Caucasian admixture in this population is estimated to be between 2 and 7%.

Alaska↗

Intra- and interobserver error in craniometry: a cautionary tale.

This study investigates intra- and interobserver measurement error in craniometry. Data consists of 72 craniometric measurements taken on a series of 28 Sadlermuit Eskimo crania. Utermohle measured the series twice; Zegura measured it once. Statistical procedures used to demonstrate measurement imprecision include the mean difference, the method error statistic, two-way anova without replication, the t-test for paired comparisons, Fisher's distribution-free sign test, and the t-test for independent samples. The result indicate less intraobserver repeatability than expected as well as an alarming lack of interobserver reproducibility for many of these craniometric measurements. We hope these results will serve as a caution against the widespread belief that craniometric measurements are always produced with a high degree of precision by experienced craniometrists. In addition, these results suggest that investigators employing craniometric measurements to study population affinities, functional morphology, forensics, fossil primates, and human microevolution might profit from conducting a measurement error analysis as an important baseline for the interpretation of the biological significance of their results.

Cephalometry↗

Physical growth of St. Lawrence Island Eskimos: body size, proportion, and composition.

Growth patterns of body size, proportion, and composition were analyzed in 57 male and 56 female Eskimos from St. Lawrence Island in the Bering Sea, ranging in age from 1.23 through 19.82 years. Age-groups means for whites and blacks of the U.S. Health Examination Survey served as reference data. Relative to HES data, the Eskimo sample were shorter with lower values for leg length, while there were no differences from the reference values for sitting height. The Eskimos also had higher values of Quetelet's Index, the sitting height/height ratio, and the upper arm muscle circumference, while there were no differences in body weight or triceps skinfold thickness. Differences from the reference data were more pronounced in males than in females. The growth patterns for size and body proportion are in conformity with known relationships between morphology and climate.

Adolescent↗

Periodontal disease in the prehistoric Ipiutak and Tigara skeletal remains from Point Hope, Alaska.

Two large groups of prehistoric Eskimo skeletons from Point Hope, Alaska, were evaluated for dental wear and several measures of periodontal disease. Occlusal attrition was found to increase steadily with increasing age. Crown height decreased proportionately. Assessing periodontal disease by inspecting apparent alveolar recession was judged ineffective due to possible supereruption. Infrabony pockets, the result of severe localized periodontal disease indicated that in Ipiutak people between the ages of 25 and 30, and Tigara people between 35 and 40, more dental sites were affected by periodontal disease than were not. This suggests a cultural, genetic, or dietary difference between the two groups. Male/female differences were slight in all parameters studied.

Adolescent↗

HLA types of mummified Eskimo bodies from the 15th century.

In 1978 the bodies of eight Eskimos were discovered in two tombs among the rocks at Qilakitsoq in the Umanak District on the west coast of Greenland. By C14 analysis at the Danish National Museum the burial was dated around A.D. 1460. The climatic conditions have been favorable for the preservation of the bodies, which were freeze-dried by nature to almost the consistency of wood. With skin and muscle tissue from the thigh, a human leukocyte antigen (HLA) type determination was carried out by means of a microabsorption method developed in this laboratory on spleen tissue from recently deceased persons (Hansen and Gürtler, 1979, 1982). The aim of the HLA determinations of these mummies was to reveal possible family relationships, and to see whether the HLA antigens found would be typical for now-living Eskimo populations. The results indicate that two families were buried, one in each of the two tombs.

Genetic Variation↗

Morphologic characteristics of the Alaskan Eskimo dentition: IV. Cusp number and groove patterns of mandibular molars.

Data on the permanent dentition of 63 coastal and 33 inland Alaskan Eskimos are presented. The number of cusps and groove pattern of the mandibular molars were recorded. Agenesis of the mandibular third molars was classified and the mesiodistal and buccolingual crown diameter was measured on the first and the second mandibular molars. The predominant pattern of the lower first molars was Y5, while for the second molar the dominating patterns were +5 and +4. In the lower third molar, +5 was found in the majority of cases. For M1 and M2, men showed a stronger tendency toward a conservative pattern than did women. In the case of M2, the inland population exhibited a more conservative trait than did the coastal population. No connection was seen between the groove pattern and agenesis of M3, however, a reduction in the mesiodistal crown diameter for the second molars was seen when the number of cusps is reduced from 5 to 4.

Alaska↗

Effects of age and sex on the amount and distribution of mineral in Eskimo tibiae.

The bone mineral content (BMC), bone width, and cross-sectional moment of inertia (CSMI) of 141 Alaskan Eskimo tibias were measured using photon absorptiometry. The effects of age and sex on the bones' structural properties were studied. It was found that in women, BMC decreased by 50% between the third and sixth decades, but that of the males did not decline significantly with age. This was true of the CSMI as well, for bending in both the anteroposterior (AP) and mediolateral (ML) planes. This result is different than that in some other prehistoric native American populations, where tibia CSMI increases with age in both sexes. The CSMI values were significantly higher in men than in women. Also, in men the AP CSMI was 55% larger than the ML CSMI; in women this difference was only 25%, and declined with age. Since the tibia is preferentially loaded in the AP plane by locomotor activities, the platycnemic differences between the sexes may reflect sex-related differences in activity which become more pronounced with age. The non-destructive method for obtaining data on the cross-sectional geometry of dry bones which is described here may be useful in studying other archaeological collections.

Adult↗

A population study of the jugular foramen bridging of the human cranium.

The author previously proposed a simple standard for diagnosing the jugular foramen bridging in man. The incidence of this bridging trait was investigated according to that standard in nine cranial series of East Indians, Micronesians, Japanese, Ainu, Mongols, Aleuts, Alaskan Eskimos, Canadian Eskimos, and Ontario Iroquois. No sex difference in incidence of the trait was recognized. Side difference in trait incidence was also slight but was statistically significant in the combined series of all the population samples examined. The bridging trait occurred more frequently on the right side than on the left side. Occurrences of the bridging trait were definitely associated between sides. Incidence of the trait was less in East Indians, Ontario Iroquois, and Micronesians, but greater in Alaskan Eskimos and Canadian Eskimos, the incidences in Japanese, Ainu, Aleuts, and Mongols being intermediate. The differences in trait incidence among the nine population samples were considered to reflect the differences in genetic compositions of these specific populations.

Alaska↗

Intra- and interobserver concordance in classifying dental morphology.

A sample of 50 Kodiak Island Eskimo dental casts were observed, using standard reference plaques, three times by one observer and once by a second observer, for 47 graded and discrete morphological characters of the dentition and jaws. Although the frequency of both intra- and interobserver scoring differences between observation sessions are relatively high for some characters, statistical analysis reveals that differences are largely random in direction and cancel out. Most dental morphological variants can be observed in a ranked fashion with adequate within- and between-observer reliability. However, four traits present both within- and between-observer difficulties: the tuberculum dentale, the canine distal accessory ridge, marginal accessory cusps of the upper first premolar, and the anterior fovea on the lower first molar.

Alaska↗

Genetic variation in the Aleuts of the Pribilof Islands and the Eskimos of Kodiak Island.

A sample of Aleuts residing in the Pribilof Islands of St. Paul (N = 163) and St. George (N = 62) and Eskimo residents of Kodiak Island (N = 294) have been typed for genetic variation at 31 discrete genetic markers. Of these, 16 were polymorphic and 15 were monomorphic. Several private polymorphisms previously reported in Eskimo or Alaskan Amerindian populations were absent in both the Aleuts and Kodiak Island Eskimos. Genetic distance analysis shows considerable genetic differentiation between Aleuts and Kodiak Island Eskimos.

Alaska↗

The genetic structure of populations of Chuckotka Peninsula Eskimos and Chuckchi based on study of 13 loci of serum and erythrocyte proteins and enzymes.

The Eskimos and Chuckchi of the Chuckotka Peninsula were studied at 13 loci of serum and erythrocyte proteins and enzymes by electrophoresis. Six loci-including albumin, transferrin, carbonic anhydrase I and II, monoamine oxidase, and superoxide dismutase-were monomorphic in the studied populations. The mean frequencies of alleles in nine polymorphic loci of Chuckotka Eskimos and Chuckchi, Eskimos of Alaska, Canada, and Greenland, some Mongoloid populations of Siberia, American Indians, and Lapps of circumpolar areas of Western Europe were obtained. The genetic distances between these populations were calculated. The Eskimos of Chuckotka were closest to the Alaskan Eskimos. The relative heterozygosity of Chuckotka Eskimos was calculated and was the highest in Chuckchi. The average heterozygosity in Eskimo populations increased in the following order, from least to greatest: Chuckotka Eskimos, St. Lawrence Island Eskimos, Alaskan Eskimos, Greenland Eskimos, and Canadian Eskimos. The average heterozygosity of the Chuckchi was similar to that of Western Hemisphere Eskimos.

Alaska↗

Dermatoglyphic and anthropometric relationships within the Iñupiat (Eskimo) hand.

On the basis of earlier findings with Easter Islanders suggesting a positive correlation between dermatoglyphic variables and hand anthropometric measurements, the present study was designed to determine if such a relationship could be generalized to another population, namely, Iñupiat (Eskimo). Since some dermatoglyphic and anthropometric variables were available for both sides of the body, the extension of this study to explore the question of asymmetry was also possible. The Iñupiat sample numbered 142 male and 176 female adult inhabitants of five Alaskan North Slope communities. The major findings of this study included, for males, significant negative correlations between left arm length and digital ridge counts and positive relationships between the palmar variable of axial index and hand length on both hands. For females, the hand breadth/length index was negatively related to most of the digital variables. Very little definitive information regarding the relationship of the asymmetry variables between the two types of measures was ascertained.

Adult↗

A quantitative investigation of irregular cuspules in human maxillary permanent molars.

The frequency of occurrence of anomalous cusps or tubercles on human upper first molars was investigated in seven racial populations using moiré contourography, which permits the three-dimensional measurement of minute cusps. Tubercles on the mesial marginal ridge were more frequently found in Mongoloid populations (Japanese and Eskimo) than in others. The frequency of the protoconule was high in Eskimos and Negroids (Bantu and San). The lingual paracone tubercle (mesial cusp) showed a particularly high frequency in Australian aborigines. The metaconule was rare or absent in all of the populations. Caucasoid groups (Dutch White and Asiatic Indian) showed generally low frequencies of all these abnormal tubercles, especially the distal accessory cusp (C5). Racial differences in the frequencies of occurrence may offer a key to understanding the adaptive significance of these traits and human microevolution. Confusion in nomenclature for upper molar tubercles is also discussed.

Asian People↗