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[Arytenoid dislocation caused by endotracheal intubation].

We experienced arytenoid dislocation in a 17-year-old man with no significant medical history, who underwent anterior cruciate ligament reconstruction under general anesthesia. After induction of anesthesia, the trachea was easily intubated with an 8.0 mm cuffed endotracheal tube. The operation lasted approximately four hours. The patient was extubated uneventfully. On the first operative day, the patient complained of hoarseness. Four weeks had passed before the diagnosis of right arytenoid cartilage dislocation was made by fiberoptic laryngoscopy. Voice therapy was started. Three weeks after starting voice therapy, the patient's voice was restored almost to the preoperative status.

Adolescent↗

First report of a case of osteoma of the larynx.

Osteomas are common in otolaryngology, as they often involve the skull and facial bones. On rare occasions, these tumors have also been found in the temporal bone and the tongue. Until now, osteomas have not been encountered in the larynx. We describe the case of a patient who came to our institution with hoarseness and dysphagia and who was found to have an osteoma of the larynx. Radiographic imaging, endoscopy, and pathologic classification confirmed the diagnosis. To our knowledge, this is the first reported case of an osteoma of the larynx.

Aged↗

Gastroesophageal reflux disease: extraesophageal manifestations and therapy.

Gastroesophageal reflux disease (GERD) can present with both typical symptoms such as heartburn and regurgitation as well as atypical symptoms. These symptoms may include chest pain, asthma, chronic cough, hoarseness, otitis media, atypical loss of dental enamel, idiopathic pulmonary fibrosis, recurrent pneumonia, chronic bronchitis and even sudden infant death. The diagnosis of GERD in these patients can often present a challenge and usually requires a combination of selected testing and therapeutic trials. Acid suppression by using proton pump inhibitors remains the treatment of choice in GERD, but some patients will also respond well to antireflux surgery. This article addresses the presentations, diagnostic challenges, and therapeutic opportunities in GERD patients with atypical presentations.

Aged↗

Emergency cricothyrotomy: long-term results.

In 1996 we reviewed the literature and reported on our own series of emergency cricothyrotomy (EC) patients. The success rate in obtaining an airway was very good. The survival rate was also acceptable. However, there have been no reports of long-term results of EC. We retrospectively reviewed the long-term results in 27 survivors of 65 original EC patients. The average length of follow-up was 37 months (1-77 months). In 13 patients no airway problems were found. The remaining 14 patients had only minor problems such as hoarse voice and mild untreated stenosis. Of these 27 patients, however, only seven were doing well. Five patients had relatively minor problems such as the need for a gastrostomy tube, minor shortness of breath, or minor neurological problems. Fifteen patients had major problems: cervical spine injuries, changes in mental status, need for permanent nursing home care, seizure disorders, or injuries that precluded their working. In most cases these problems were due to the underlying disease process. EC is effective in obtaining an airway with a low incidence of later severe airway problems. However, many of these patients do poorly overall.

Adult↗

An unusual presentation of thyroglossal duct cyst.

Thyroglossal duct cyst usually presents as a painless swelling in the mid-line of the neck. This is the first documented case of an acute presentation of hoarseness and multi-loculated swelling. It also contrasts the limitations of ultrasonography with the accuracy of magnetic resonance imaging in such atypical swellings.

Adult↗

Ear, nose and throat manifestations of relapsing polychondritis in a child.

Relapsing polychondritis is a rare disorder, that can present initially to Otolaryngologists and can easily be overlooked due to its relative rarity and atypical initial symptoms and signs. Here we report on a 12-year-old schoolboy who presented initially with ear, nose and throat manifestations, including stridor, cough, hoarseness, sore throat and fever. The other clinical signs such as nasal tip, depression and softening of right auricle, developed subsequently. The clinical features, laboratory investigations, diagnostic criteria and treatment options were discussed with a brief review of literature.

Antirheumatic Agents↗

A case of laryngeal carcinoma appearing as a goiter.

We describe the case of a 41-year-old man with hoarseness and a hard, fixed mass in the anterior cervical region. He was referred to our endocrinology service for evaluation of possible thyroid cancer. The results of laboratory tests of thyroid function were normal. Indirect laryngoscopy revealed paralysis of the left hemilarynx and the presence of a large vegetating lesion. Computed tomography of the neck disclosed the presence of a mass in the anterior region, along with invasion and destruction of the adjacent structures. The cytologic diagnosis was established by analysis of a fine-needle aspiration biopsy specimen, which revealed a squamous cell carcinoma. The final diagnosis was carcinoma of the larynx.

Adult↗

[Diagnosis and treatment of glomus jugulare tumor].

OBJECTIVE: To investigate the clinical features, diagnosis, and treatment of glomus jugulare tumor. METHODS: The data of 37 patients of glomus jugulare tumor diagnosed by digital subtraction angiography (DSA) and/or operation and pathology, 14 males (37.8%) and 23 females (62.2%), with an average age of 37.2 (3.5 approximately 66 years) and an average course of 4.3 years (1 month - 19 years), were analyzed. RESULTS: The tumor was located in the left ear in 19 cases, in the right ear in 17 cases, and in both ears in 1 case, totally 38 ears. The tumor was chromaffin in one case with hypertension. One case was complicated by ipsilateral carotid body tumor, and 2 cases were complicated by ipsilateral cholesteatoma. Thirty cases (81.1%) presented pulsatile tinnitus and hearing loss as the main symptoms. Thirteen cases (35.1%) were diagnosed as glomus jugulare tumor at the first visit, and 24 cases (64.9%) were diagnosed as other diseases with an average misdiagnosis period of 4.4 years. Eighteen tumors originated from typanum and 28 tumors from glomus jugulare. According the Fisch classification 1981, the tumors in 11 ears were type A, in 7 ears were type B, in 7 ears type C, in 5 ears type D1, and in 8 ears type D2. All cases, except the one with bilateral lesions, underwent operation. The tumor was completely resected in 30 cases. Postoperatively, facial paralysis was seen in 6 cases, dizziness, hoarseness, and subauricular necrosis was seen in one case respectively. Of the 25 patients followed up with a mean follow-up time of 5.2 years (1.1 - 16.1 years), 3 died of lung cancer, neuroblastoma, or extensive involvement of glomus jugulare tumor respectively, 19 survived without tumor, and 3 survived with the tumor. CONCLUSION: Glomus jugulare tumor is likely to involve surrounding important tissues, and to be misdiagnosed. Early surgical removal of the lesion is important.

Adolescent↗

Subglottic leiomyoma: report of a case.

Subglottic leiomyoma is a rare disease. We encountered such a tumor in a 7-year-old boy who was transferred to our hospital with respiratory distress and hoarseness of 2 week's duration. Stridor was noted and flexible fiberoscopy revealed a huge mass over the subglottis. The tumor was removed endoscopically. Pathologic examination disclosed a leiomyoma. The patient recovered well and no recurrence was noted during 17 months of follow-up. Although subglottic leiomyoma is rare, it should be included in the differential diagnosis of a subglottic tumor.

Child↗

[Importance of voice quality evaluation in the assessment of treatment outcome after endolaryngeal microsurgery].

The aim of the study was to compare subjective and quantitative voice characteristics changes after endolaryngeal microsurgery with respect to different postoperative follow-up term. We evaluated 80 surgically-treated patients aged 14-81 years (mean 42.6+/-13.8 years) with benign vocal cord (VC) lesions (polyps, n=37; cysts, n=16; Reinke's edema, n=18; papilomata, n=9). Patients were evaluated three times - before operation, less than two weeks (mean 1.0+/-0.4) following the operation and more than two weeks (mean 6.5+/-3.9) following the operation. Control group consisted of 122 healthy voice patients. Subjective voice evaluation composed of experts assessment (GRBAS hoarseness scale, visual analogue scale (VAS) of voice quality) and patients self-evaluation (VAS, voice handicap index, and the impression of what repercussions the voice problem has on professional life and emotions). Seven quantitative voice parameters obtained from voice range profile, laryngostroboscopy and registering of maximum phonation time were analyzed as well as overall vocal dysfunction degree (VDD). The data of second postoperative examination were statistically significantly better compared to the first postoperative follow-up (p<0.001). During the first postoperative examination the subjectively healthy voice (G=0) was found for 13.8% (11), quantitatively (VDD=0) for 22.5% (18) of patients, during the second - 63.8% (51) and 53.8% (43). The best results were for patients with vocal cords polyps. The complex voice assessment may be useful for evaluation of voice function recovery and efficacy of surgical treatment.

Adolescent↗

Pseudo tumoral laryngeal tuberculosis.

An 11-year-old female child presented with high grade intermittent fever and cough for a duration of 6-7 months and hoarseness of voice for 6 months. Skiagram of the chest showed evidence of miliary mottling. Direct laryngoscopic examination revealed inflammatory swelling over left vocal cord. The biopsy of the swelling showed chronic granulomatous lesion. Patient improved remarkably with anti-tubercular therapy.

Antitubercular Agents↗

Primary squamous cell carcinoma of the false vocal cord.

Primary squamous cell carcinoma of the false vocal cord may arise on the surface mucosa or may arise beneath it and continue to grow deeply, presenting only a smooth tumescence of the area. These lesions may not cause hoarseness until late in the course of development. Diagnosis of submucosal primary lesions may present difficulty. Widefield laryngectomy is recommended for small primary lesions of the surface mucosa of the false vocal cord. Such lesions do not show edema of the tissues or deep ulceration and do not cause limitation of motion of the false or true vocal cords. For advanced lesions of the false vocal cord which arise on the surface mucosa and cause edema, ulceration and limitation of motion without enlargement of cervical nodes, widefield laryngectomy and elective block dissection of the neck should be done at the primary operation. Patients with such a primary lesion and metastasis to cervical lymph nodes, which are resectable, should be treated in a like manner.Patients with submucosal primary squamous cell carcinoma of the false vocal cord should be treated with widefield laryngectomy and block dissection of the neck, whether or not palpable resectable lymph nodes are noted in the neck. Apparently these lesions metastasize early and widely.

Carcinoma↗

[Differential diagnosis of GERD].

It was widely accepted that the prevalence of GERD is lower in Oriental countries compared to Western countries. But the incidence of GERD has recently increased in Japan. The most commonly recognized manifestation of GERD is heartburn or a substernal burning sensation in the chest. Most patients with reflux esophagitis complain of typical symptoms such as heartburn, regurgitation or dysphagia. However, some patients complain of atypical symptoms such as hoarse voice, chronic cough, adult-onset asthma or vocal cord polyps. It is not always easy to diagnose atypical symptomatic patients as GERD. If patients who complain of these atypical symptoms have not improved with common medical treatment, GERD should be the consideration in its differential diagnosis.

Asthma↗

Cavernous lymphangioma in the laryngeal ventricle in an adult patient.

Lymphangiomas of the larynx are quite rare and even rarer in adults. Isolated cavernous lymphangioma in the laryngeal ventricle was diagnosed in a 47-year-old woman. The patient presented with hoarseness with a history of three months. Direct laryngoscopy performed under general anesthesia showed a large, smooth, gray-reddish tumor above the right vocal fold, originating from the right ventricle. The tumor was removed through a micro-laryngoscopic procedure with cold instruments. Histopathologic diagnosis was cavernous lymphangioma. There was no local recurrence a year after the operation.

Diagnosis, Differential↗

A case of granulocytic sarcoma during complete remission of acute myeloid leukemia with multiple masses involving the larynx and nasopharynx.

A thirty-seven-year-old male patient presented with dysphagia and hoarseness six months after complete remission of acute myeloid leukemia (AML-M0), which had been treated with chemotherapy. Physical examination revealed left vocal cord paralysis and involvement of the 9th, 10th, and 12th cranial nerves. Sagittal and axial magnetic resonance scans of the nasopharynx and neck showed a mass in the left retropharyngeal and perivertebral regions, 6x4 cm in size; another mass in the left vallecula, and infiltration of the right preepiglottic tissue by another mass of 2 cm. There was no bone marrow involvement. A diagnosis of granulocytic sarcoma without leukemia relapse was made and the FLAG-Ida regimen was administered, after which partial regression of the masses was observed. However, the patient died due to a pulmonary infection on the 17th day of chemotherapy.

Adult↗

[Mucoepidermoid carcinoma of the larynx: a case report].

Mucoepidermoid carcinoma of the larynx is an uncommon malignancy. It is mostly located in the supraglottis. It frequently occurs in middle-aged and elderly men. The treatment is primarily surgical. A 42-year-old man presented with a complaint of hoarseness of six-month history. Examination revealed a swelling involving the right arytenoid, false cord, and vocal cords. The right vocal cord was fixed. A biopsy obtained from the lesion showed a low-grade mucoepidermoid carcinoma. He underwent total laryngectomy and right functional neck dissection.

Adult↗

[Malignant jugular paraganglioma: a case report].

Paragangliomas are usually benign tumors. Overall, less than 10% of all paragangliomas become malignant. Although the indicator of malignancy is regarded as detection of histopathological findings of tumor by some authors, most authors accept extension to regional lymph nodes or distant metastasis as the only reliable indicators of malignancy. A 66-year old woman was admitted to our hospital with hearing loss, vertigo, and hoarseness. CT examination revealed a mass in the left jugular foramen. The tumor was confirmed as malignant paraganglioma. Indicators of malignant paragangliomas are discussed in this article.

Aged↗

Laryngeal leiomyosarcoma.

Laryngeal leiomyosarcoma is rare. The authors report the case of a 48-year-old patient who presented with progressive hoarseness. This symptomatology was associated with a laryngeal tumour. Immunohistopathological study indicated a leiomyosarcoma. Acute dyspnoea resulted in an urgent tracheostomy, followed by total laryngectomy without neck dissection later. In the light of this observation and a literature review, histopathological characteristics, clinical aspects and therapeutic indications will be discussed for this localisation.

Dyspnea↗