Sedation threshold, spiral after-effect and overinclusion.
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A group of 16 chronic schizophrenic subjects were compared with 15 age-matched control subjects for interocular transfer of movement after-effects. Contrary to the hypothesis that schizophrenic subjects would show a deficit on this measure schizophrenics showed increased transfer compared to the controls. This effect is not due to response perseveration and is not correlated with length of hospitalization, age or dose of antipsychotic drugs. It is suggested that the effect reflects a deficit in 'inhibitory processes' in schizophrenia.
The duration of the movement after-effect (MAE) was measured in 90 males and 64 females, aged from 7 to 87 years, between 10.30 and 17.00 h. MAE duration was an inverted U-shaped function of age, with subjects in their 30s reporting longest effects. MAEs were longest in mid-morning and declined throughout the day. Females reported shorter MAEs than males.
The theoretical point of departure here was the assumption that a psychogenic vertigo patient displaces affect, or experience of anxiety to one of dizziness, the dizziness serving as an anxiety equivalent. This is seen to imply a change in the locus of experience from the me to the not-me sphere. "Percept-genetic" techniques and a spiral after-effect measurement were used to compare 23 patients with presumed psychogenic vertigo with a control group matched in sex, age, education and occupation. Results of the percept-genetic techniques showed the patients to display stronger signs of affect anxiety than subjects in the control group. Also two main subgroups of patients were differentiated with the help of the descriptive instruments, one group with signs of a primitive-hysteroid mode of functioning, the other with signs of an obsessive-compulsive mode. For both subgroups the suggested displacement mechanism seemed to be functioning. Its apparent effect differed, however, for the two subgroups: in the "primitive-hysteroid" group the displacement mechanism was more effective. The "obsessive-compulsive" group showed stronger signs of affect anxiety, dizziness here being better characterized as a concomitant than as an equivalent of anxiety. Results of a follow-up two years after the investigation also showed a poorer development of symptoms within the "obsessive-compulsive" group.
1. Perceptual adaptation to a 30 or 45 degrees visual tilt was induced in human subjects by means of prismatic spectacles worn for 5-7 days. Relative contrast thresholds and the amplitudes of the occipital potentials to vertical and oblique gratings were studied.2. During continuous exposure to the tilted visual environment the normal differences between contrast thresholds for vertical and oblique targets decreased or were no longer significant. In all subjects the change from control threshold differences was significant at the 0.005 level.3. During the course of adaptation the difference in amplitude of the potentials evoked by vertical and oblique oscillating gratings also decreased. The changes with respect to control differences were significant at the 0.005 level in each subject.4. Intermittent exposure to tilt in one subject resulted only in minor adaptation of the apparent vertical, and the evoked potential differences did not change from control levels.5. The changes are interpreted as suggesting that plastic changes in the extraretinal mechanism responsive to target orientation occur during adaptation to prismatic tilt.