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At least 811 records · Page 45Linked to original sources

Fibroma of tendon sheath arising from the radio-ulnar joint.

A report of a 65-year-old male with a tumor arising from synovial tissue of the radio-ulnar joint. On magnetic resonance imaging, the tumor was demonstrated as a heterogeneous and lobulated mass with a low signal intensity both in T1- and T2-weighted images. Histological findings of the tumor were identical to those of fibroma of the tendon sheath. In the peripheral villous synovial tissue, several small and fibrous nodules were observed, and their histological features were identical to those of the main tumor. Immunohistochemically, the tumor cells showed diffuse and intense reactivity to vimentin, muscle actin and S-100. These results indicated that the tumor might be a fibromatous analog of synovial chondromatosis.

Actins↗

Infantile digital fibroma treated with mohs micrographic surgery.

BACKGROUND: Infantile digital fibroma (IDF) is a rare benign fibrous tumor of childhood that frequently recurs despite local excision. Conservative, nonsurgical management may result in regression and/or joint deformity. OBJECTIVE: To describe the histologic features of IDF and discuss a case excised using Mohs micrographic surgery (MMS). METHODS: Case report and review of the clinical, histologic, and ultrastructural features. RESULTS: Characteristic inclusion bodies of actin were identified with hematoxylin and eosin, Masson's trichrome, and rapid actin immunostain. The tumor was debulked and the majority was removed after one stage of MMS, except where the deep margin approached the joint space. The defect healed by secondary intention. At 2 years the patient had no recurrence or functional joint deformity. CONCLUSION: MMS is a surgical treatment option for IDF.

Fibroma↗

Rare mesenchymal lesions: Hamartoma of the chest wall and juvenile active ossifying fibroma in siblings.

Mesenchymal hamartomas of the thorax are known as rare dysontogenetic tumorous non-neoplastic lesions. The juvenile active ossifying fibroma (JAOF) also is considered as a benign tumor like lesion of the mesenchymal connective tissue. The authors report the cases of 2 siblings-a 2-year-old girl with a hamartoma of the chest wall and her 4-year-old brother with a JAOF. The girl had bilocular mesenchymal hamartoma in the area of the 8(th) rib diagnosed in the first year of life, which was surgically removed completely. Her brother had been treated for JAOF of the right nasal sinus area diagnosed at the age of 15 months. Both lesions are extremely rare mutations of the local tissue, which occur typically in early childhood and continue benignly after surgical resection, but such a familial occurrence in siblings has not yet been reported. Furthermore, according to the histologic findings, the JAOF also could be seen as a hamartomatous lesion.

Bone Neoplasms↗

Desmoplastic fibroma of the rib.

We present a 17-year-old male patient who had a desmoplastic fibroma. The diagnosis is histologically verified and differentiated from other tumors. The rare localization of this benign lesion in the rib is of particular interest.

Adolescent↗

Successful removal of papillary endocardial fibroma.

We report a case of systemic embolization secondary to a small papillary endocardial fibroma, a rare cardiac tumor. It was attached to a chords of the mitral valve by a short stalk. The tumor was successfully excised and the mitral valve was preserved. Two-dimensional echocardiography played the major role in the diagnosis of this small endocardial tumor.

Adult↗

[Pathogenesis of fibrous cortical defect and non-ossifying bone fibroma].

We were able to show in eighty-one cases that fibrous cortical defects or non-ossifying fibromas of the bone occur only in areas, where tendons insert into the perichondrium of the epiphyseal plate. During growth these tumor like lesions move towards the diaphysis following a cortical line, which begins at the point of insertion of the tendon and is parallel to the longitudinal axis of the bone.

Adolescent↗

[Fibrous bone dysplasia and ossifying bone fibroma in the orbital and periorbital region with special reference to CT].

Fibro-osseous conditions affecting the craniofacial bones pose a complex diagnostic problem. Differentiation between monostotic fibrous dysplasia (FD) and ossifying fibroma (OF) is only possible by correlation of clinical, radiographical and histopathological features. CT was superior to conventional radiography/polytomography in defining exact extent and site of lesions and additional lesions, in verifying aetiology of secondary complications, as well as in depicting lesions and tandem-lesions simulating FD and OF. Density of fibro-osseous conditions was variable due to the ratio of fibrous stroma and metaplastic bone present. Density measurements in FD were 32-695 HU, in immature types of OF, consisting mainly of fibrous and osteoid tissue, 30-250 HU and could reach 690 HU in mature OF, but were definitively lower than normal bone in all our cases. Focal intrinsic nonhomogeneity was more significant in mixed types of FD and immature OF.

Adolescent↗

[The contribution to clinic, pathology and therapy of ossifying fibroma in the long tubular bones (author's transl)].

The ossifying fibroma which rarely localizes itself in the long tubular bones is usually to be found in the face and skull. This contribution involves the therapie of such a case and its follow-up and its also shows you the differential diagnosis of this tumor in contrary to other bone tumors. This work led to the compiling of the publications of the world literature according to DOKDI-Bern and the references to the scientific works being used.

Bone Neoplasms↗

[Fibrous metaphyseal defect (fibrous cortical defect, non-ossifying fibroma) (author's transl)].

Fibrous cortical defect and non-ossifying fibromas can be classified together as fibrous metaphyseal defects (FMD) since they have the same pathological substrate, with a tendency to the same localisation around the knee, and occurring at the same age. They have a tendency to spontaneous healing, are clinically silent and are usually discovered accidentally during radiological examination. A radiological survey of 5.674 metaphyseal regions in the upper and lower extremities of 2.065 unselected patients aged one to 20 years revealed an incidence of 1.8%; exclusive examination of the distal femur showed an incidence of 2.7%. 96% of all lesions were in the lower extremities and only 4% in the upper. The marked discrepancy in the incidence rate between American and German publications is discussed.

Adolescent↗

[Fibrous metaphyseal defect (fibrous cortical defect, non-ossifying fibroma). Paper II: differential diagnosis (author's transl)].

FMD, whether in the stage of a fibrous cortical defect or a non-ossifying fibroma, possesses very characteristic radiological appearances which rarely make it necessary to resort to biopsy. In order to avoid mistakes, it is necessary to observe strictly the known radiological features: metaphyseal position, clearcut relationships to the cortex, well defined margins, maximal size 6 to 7 cm., presence during growth, rarely observed in the upper extremity. The differential diagnosis, which needs to be considered only rarely, is discussed.

Adolescent↗

Cemento-ossifying fibroma of maxillary and sphenoid sinuses: case report and literature review.

We report a case of cemento-ossifying fibroma (COF) involving the maxillary and sphenoid sinuses and review the literature in order to study the clinical features, imaging findings and histopathologic characteristics of COF. Special care was taken to distinguish this lesion from cemento-osseous dysplasia (COD). It is almost inevitable that differential diagnosis of COD and COF will be complicated by the fact that some pathologic features are shared by both lesions. A combined study incorporating clinical, radiographic and pathologic findings is important in order to ensure an accurate diagnosis. Postoperative follow-up is essential, especially in cases where incomplete removal of the COF was performed.

Adult↗

Lhermitte-Duclos disease associated with neurofibromatosis type-1 and non-ossifying fibroma.

Lhermitte-Duclos disease (LDD) is a rare cerebellar disorder of uncertain pathogenesis characterized by enlargement of cerebellar folia. Magnetic resonance imaging is the diagnostic modality of choice and usually distinguishes the LDD by its characteristic "striated or laminated pattern" appearance. Various additional abnormalities have been reported in association with LDD. We report a case of LDD coexisting with neurofibromatosis type 1 (NF-1) and non-ossifying fibroma.

Bone Neoplasms↗