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Results for “DENTAL PULP”

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At least 811 records · Page 45Linked to original sources
PubMed1989

[The significance of endogenous peptides for dental pulp pain].

The increase of knowledges in the field of endorphines and other peptides causes new aspects of development and transmission of dental pain. Methionin-enkephalin (ME) and substance P (SP) are found also in the dental pulp and the dentine. The concentration of SP is higher in the pulp, than in some other tissues. The concentration of both, ME and SP, in the endodont is different with respect to different functional situations, e.g. it is lower in case of pain. We suppose, there is a peptiderg reception and transmission of pain in dentine. Interaction with this new system opens new ways for opposing pulpal pain.

Dental Pulp↗
PubMed1991

A review of aging of dental components and a retrospective radiographic study of aging of the dental pulp and dentin in normal teeth.

A review of aging of dental components is followed by a clinical radiographic study. Patients received radiographs at 5-year intervals with a 10-year minimum followup. Data obtained were age, gender, tooth, and systemic diseases. Measurements taken were tooth length, coronal length, apical length, cervical width, midroot width, and apical width. Root canal shrinkage was calculated vertically, horizontally, and as a combination (vertical and horizontal). Results showed statistically significantly more shrinkage in men, the elderly, and people with calcification-related diseases. Shrinkage increased with advancing age. With further studies, radiographically determined root canal measurements could prove useful in anthropology, forensics, and as a biomarker of aging.

Adult↗
PubMed1977

PH and the effect of fluoride and zinc on protein and collagen biosynthesis in rabbit dental pulp in vitro.

The effect of pH in the range 6.6-8.2 on the incorporation of 14C-proline into the rabbit dental pulp incubated in vitro has been studied. The amount of label in the cold TCA-soluble pool, total protein, and hydroxyproline (i.e. collagen) of the pulp tissue increased linearly with pH in all three fractions. A similar increase was found in the amount of labeled total protein and collagen recovered from the incubation medium. The results indicated that the uptake of 14C-proline into the TCA-soluble pool was the pH-sensitive step, whereas the incorporation into protein, formation of hydroxyproline, and the release of labeled macromolecules into the medium were not affected to any measurable degree by the ambient pH. In this system, zinc (60 micrometer) had less effect on the incorporation of 14C-proline into the different fractions of the pulp tissue at pH 6.6 as compared with pH 7.4, whereas with fluoride (1.3 mM) an increased inhibition of the uptake of 14C-proline into the TCA-soluble pool and the incorporation into total protein was found upon lowering the pH to 6.8. The inhibitory effect of zinc and fluoride on the release of labeled total protein and collagen into the incubation medium was not affected when the pH was lowered.

Animals↗
PubMedDate not supplied

[Experimentation of apiarian preparations for the direct and the indirect capping of the dental pulp].

With a view to extend the range of biologically active preparations for the direct and the indirect capping of the dental pulp the authors have used a paste made from an alcoholic solution of propolis and zincoxyde. The study was carried on in 150 teeth with indirect capping of deep cavities, and 50 teeth with direct capping. The evolution of the cappings was followed clinically, radiologically and morphologically. The results obtained showed that the paste with propolis exerts effects similar to those of zinc eugenate. The morphologic study of the indirect capping showed that secondary dentin developed shortly after the application of the paste, and that it was followed by the development of pulpolites and the sclerous transformation of the pulp. In teeth with direct capping a protective film developed at the opening of the dental chamber. With time the pulpal wound undergoes cicatrization by a process of fibrosis and there is a trend to remineralization. No areas of pulpal degenerescence were found the rest of the pulpal tissue, and this suggests that the paste is more histophilic than the pastes based on calcium hydroxide, with which an area of necrosis occurred at the opening of the chamber, and calcium and fibrous degenerescence occurred in the coronal pulp.

Dental Pulp Capping↗
PubMed1991

In situ testing of CO2 laser on dental pulp function: effects on microcirculation.

The effect of CO2 laser irradiation on pulpal microcirculation was studied in cat canines. The enamel surfaces of 4 teeth were exposed with energy densities of 304-1440J/cm2, using either a handpiece or a microslad, with a focal spot of 0.21mm and 0.33mm respectively. Pulpal blood flow (PBF) before and following lasing was recorded through the intact tooth surface by a laser Doppler flowmeter. CO2 laser irradiation caused an increase in PBF, which was immediate and transient. The PBF increase was higher in a large pulp than in a small pulp, and it was inversely related to the focal spot size. These findings confirm that the dental pulp is thermally affected by CO2 lasing of the tooth surface, however, without extensive pulp coagulation. It is concluded that the effects of laser irradiation on the pulpal microcirculation may be studied in situ by means of the presented methodology.

Animals↗
PubMed2005

[Proliferation and ALPase activity of human dental pulp cells in response to lipopolysaccharide in vitro].

PURPOSE: To investigate the effects of LPS on proliferation and ALPase activity of human dental pulp cells (HPCs). METHODS: HPCs were cultivated from connective tissue explants digested with collagenase type I. The expression of mCD14 was determined, and the effects of LPS on proliferation of HPCs at the concentrations of 0.1μg/ml,1μg/ml and 10μg/ml were observed by FCM. The effects of LPS tested on ALPase activity were examined. X(2) test and one-way ANOVA were used in statistical analysis respectively. RESULTS: The results showed that LPS receptor mCD14 was not present in HPCs. LPS inhibited proliferation of HPCs (P<0.01) and ALPase activity in HPCs (P<0.05) at the concentrations of 0.1μg/ml,1μg/ml and 10μg/ml. CONCLUSIONS: It is concluded that LPS tested inhibits proliferation of HPCs and ALPase activity of HPCs.

Alkaline Phosphatase↗
PubMed1989

[Laser Doppler Flowmetry: microcirculatory studies in the dental pulp].

Laser Doppler Flowmetry permits studies of the blood circulation in circumscribed tissue areas. This measuring method may also be applied to the dental pulp if a suitable experimental design is developed. Incisor teeth of rats are used as an example to illustrate that a quantitative analysis of changes in the blood flow is possible with the aid of suitable preparation procedures.

Animals↗
PubMed2000

Responses of immunocompetent cells in the dental pulp to replantation during the regeneration process in rat molars.

Responses of immunocompetent cells to tooth replantation during the regeneration process of the dental pulp in rat molars were investigated by immunocytochemistry using antibodies to class II major histocompatibility complex (MHC) molecules (OX6 antibody), monocyte/macrophage lineage cells (ED1 antibody) and protein gene product 9.5 (PGP 9.5), as well as by histochemical reaction for periodic acid-Schiff (PAS). Tooth replantation caused an increase in both the number of OX6- and ED1-positive cells and their immunointensity in the replanted pulp, but almost all PGP 9.5-immunoreactive nerves diminished in the initial stages. By postoperative day 3, many OX6- and ED -immunopositive cells had accumulated along the pulp-dentin border to extend their cytoplasmic processes into the dentinal tubules in successful cases. Once reparative dentin formation had begun after postoperative day 7, OX6- and ED1-immmunopositive cells became scattered in the odontoblast layer, while reinnervation was found in the coronal pulp. The temporal appearance of these immunocompetent cells at the pulp-dentin border suggests their participation in odontoblast differentiation as well as in initial defense reactions during the pulpal regeneration process. On postoperative day 14, the replanted pulp showed three regeneration patterns: (1) reparative dentin, (2) bone-like tissue formation, and (3) an intermediate form between these. In all cases, PAS-reactive cells such as polymorphonuclear leukocytes (PML) and mesenchymal cells occurred in the pulp space. However, the prolonged stagnation of inflammatory cells was also discernible in the latter two cases. Thus, the findings on PAS reaction suggest that the migration of the dental follicle-derived cells into the pulp space and the subsequent total death of the proper pulpal cells are decisive factors for eliciting bone-like tissue formation in the replanted pulp.

Animals↗
PubMed1997

Regressive changes of the dental pulp complex in retained primary molars with congenitally missing successor teeth.

This study was undertaken to investigate the regressive changes occurring in the dental pulp complex (pulp, dentin, and cementum) of retained mandibular primary second molars with congenitally missing bicuspid teeth. Seventeen retained, caries free, primary molars were used. The specimens were fixed in 10% neutral buffered formalin. Fixed samples were decalcified, routinely prepared, embedded in paraffin, sectioned, and stained with hematoxylin and eosin. The results demonstrated a reduction in the pulp size, abnormal odontoblastic pattern, declined vascularity, pulp degeneration, pulp stones, accelerated formation of secondary dentin, and hypercementosis. This study suggests that these findings may be from aging and physiological defensive changes. These normal, age-induced changes are of considerable importance in the fields of endodontics, orthodontics, and pediatric dentistry.

Adult↗
PubMed1991

[Histochemical observations on enzyme activity of the dental pulp following the orthodontic therapy].

The authors studied distribution of alkaline and acid phosphatases, non specific esterase and NADH2 tetrazolium reductase in the dental pulp of children treated by fix orthodontic appliances. All the enzymes studied exhibited positive reaction, the activity, however, was lower than in the controls, except of the alkaline phosphatase. The results of the study demonstrated that the forces between 60-200 g cannot be evaluated as biologically favorable.

Acid Phosphatase↗