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[Clinical importance of inclusion cysts of nevi in bulbar conjunctiva].

We investigated 30 cases of nevi in bulbar conjunctiva histopathologically from 1980 to 1992. The patients' ages were between 5 and 85 years old (mean, 21 years). Investigated parameters of the tumors were the location, growth pattern, and the presence of inclusion cysts, melanin granules, goblet cells, and feeding vessels. Of 30 cases, 26 cases (87%) had inclusion cysts which were characteristic findings of conjunctival nevi. The mucous secretion from goblet cells may play an important role in the synthesis of inclusion cysts, but goblet cells were not found in 9 cases. This finding suggests that other secretory cells may be present. Four cases without inclusion cysts consisted of flat tumors. From this finding, the presence of inclusion cysts may be related to the growth of tumors. We conclude that the growth of the pigmented conjunctival tumors with inclusion cysts suggests a benign growth pattern. A periodical follow-up study or biopsy should be performed, if inclusion cysts are not found.

Adolescent↗

[Malignant melanoma and melanosis of the conjunctiva. Limited surgical excision and cryotherapy].

A 92 year old woman was noted to have three black conjunctival nodules and a black-brown pigmentation of the temporal conjunctiva. Extensive diffuse intraepithelial conjunctival melanomar was developed with invasive nodules. We treated this disease by judicious excision of the invasive nodules combined with cryotherapy delivered to the surrounding flat intraepithelial areas of involvement.

Aged↗

Clinical diagnosis of tumors of the conjunctiva.

Tumors of the conjunctiva are easily visible to professional and lay observers. Because of this, they are frequently a source of patient self-referral. These lesions range from benign to malignant, and a differential diagnosis often requires the collaboration of the surgeon and pathologist as well as the diagnosing clinician. This article reviews the spectrum of conjunctival lesions based on how they appear to the clinician, with brief guidelines regarding management.

Conjunctival Neoplasms↗