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At least 793 records · Page 44Linked to original sources
PubMed1997

Partial liquid ventilation in critically ill infants receiving extracorporeal life support. Philadelphia Liquid Ventilation Consortium.

OBJECTIVES: To demonstrate that a period of partial liquid ventilation (PLV) with perflubron improves pulmonary function, without adverse events, in a select group of critically ill infants receiving extracorporeal life support (ECLS) with a high likelihood of mortality. METHODS: This was an open-label, noncontrolled, phase I and II trial of PLV in two infants with congenital diaphragmatic hernia and four infants with acute respiratory distress syndrome (ARDS) who were failing to improve while receiving ECLS. PLV was performed by instilling and maintaining a functional residual capacity of sterile perflubron for 4 to 96 hours. RESULTS: Four infants were successfully weaned off ECLS for at least 3 days, and two infants (both with ARDS) are long-term survivors after PLV. All infants demonstrated lung recruitment and improved lung compliance, and there were no adverse events related to PLV. CONCLUSIONS: The study suggests that perflubron PLV is safe, improves lung function, and recruits lung volume in critically ill infants receiving ECLS. PLV therapy for infants with ARDS seems to have a great deal of promise. Based on this and other phase I and II trials, studies of PLV on selected full-term infants before ECLS have been initiated.

Emulsions↗
PubMed1982

Resting pulmonary ventilation and dead space ventilation during the menstrual cycle.

By reanalyzing our previous study (TAKANO et al., 1981) of resting ventilation and PACO2 during the menstrual cycle of eight healthy women, we found that relative to the follicular phase, a 9.4% increase in VA (p less than 0.05) and a 2.5 mmHg decrease in PACO2 (p less than 0.001) occurring during the luteal phase, both of which have been reported previously, were attributable mostly to a decrease in VD (-7.2%, 0.05 less than p less than 0.1) but not to an increase in VE (+1.9%, N.S.), the latter two changes producing an 8.7% decrease in VD/VT (p less than 0.01).

Adult↗
PubMed2006

The effects of ventilated and non-ventilated nasal packs on Eustachian tube function: nine-step inflation-deflation test results.

The effects of different types of nasal packs on Eustachian tube function have been a source of debate. Past study results have been based on single tympanometric evaluations. To our knowledge, this study is the first to use the nine-step inflation-deflation test for evaluation of Eustachian tube function in patients undergoing nasal packing. No significant difference was observed between ventilated or glove-finger nasal packs, in terms of preserving Eustachian tube function in our patient population.

Acoustic Impedance Tests↗
PubMed1977

[Variations in gas exchange and hemodynamic effects of various means of oxygen administration (spontaneous ventilation, controlled ventilation and under I.P.P.B.) in 19 severely obstructed pulmonary hypertension patients].

In 19 cases of severe chronic respiratory insufficiency by obstruction, the authors studied the haemogasometry and haemodynamic incidence of inhaling a mixture with FiO2 by various ways and in respiratory reeducation. Controled ventilation with or without manual abdominal pressure, instrumental kinesitherapy under pressure relaxor and simple oxygen inhalation. The pressure relaxor seems particularly suited to patients suffering above all from hypercapnia and obstruction because of its limited haemodynamic repercussions.

Adult↗
PubMed1982

[A Draeger-universal ventilator with an extended capacity of ventilation].

We have compared an improved Draeger universal ventilator (UV 1) with the corresponding standard model. The improvement was carried out by Draegerwerk according to our directions. The improved equipment is able to provide an increased minute volume (about 50%) and increases, therefore, the respiratory reserve for problem patients.

Humans↗
PubMed1997

Comparative evaluation of the cardiorespiratory effects of assist control ventilation vs pressure support ventilation in patients following orthotopic liver transplantation.

OBJECTIVE: 1) To compare the haemodynamic tolerance of ACV and PSV in patients mechanically ventilated after orthotopic liver transplantation; 2) to compare patients comfort during ACV and PSV. DESIGN: Prospective randomized cross-over study. SETTING: General ICU of the University of Rome "La Sapienza". PATIENTS: Eighteen patients admitted in ICU after orthotopic liver transplantation. MEASUREMENT AND RESULTS: Haemodynamic, oxygen transport and blood gas data were compared during an ACV and PSV trial (30'). A statistically significant decrease of mean pulmonary and systemic arterial pressure, PCOP, LVSWI, occurred during the PSV trial. PaO2 and DO2I decreased during PSV, but were still in supranormal range; 16 out of 18 patients described PSV as more comfortable. CONCLUSIONS: ACV and PSV provided a comparable haemodynamic tolerance in our patients, although during PSV the PaO2 was slightly decreased, probably due to decreased mean airway pressure (from 9.3 +/- 1.2 cmH2O during ACV to 6.6 +/- 1 cmH2O during PSV). PSV can be considered as a good alternative to the standard weaning techniques following orthotopic liver transplantation.

Adult↗