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Neonatal teeth association with Down's syndrome. A case report.

A case of natal teeth in a four-day-old female brought by a forty four year old mother is presented. These natal teeth were present in the upper and lower jaws. Of special interest was the shape and positions of these especially the upper tooth in the left canine region and the fact that these teeth were present in a child with Down's syndrome features. The anxiety of the mother and the desire to get them removed immediately underlines the superstition and misconceptions with which natal teeth are viewed. The multidisciplinary approach to management is also highlighted.

Down Syndrome↗

[Comparson of occlusal conditions in juveniles from residential areas with different drinking water fluoride contents (author's transl)].

The investigations reported in this paper were conducted in Karl-Marx-Stadt after 16 years from the introduction of drinking water fluoridation (1.0 ppm F), with a total of 792 randomly selected juveniles (whose average age was 14.9 years) being examined. Serving as a control group were 780 juveniles of the same age (15.4 years). The control persons were from Leipzig (0.2 ppm F). Included in the comparison with metric occlusal traits, use being made in this connection of the method for measuring occlusal traits, which was recommended in 1973 by an F.D.I. commission (COCSTOC-MOT). Despite the considerable reduction of caries in the deciduous dentition and the change in the eruptive behavior of permanent teeth, which is of great importance of the development, of dentition, no systematic differences could be observed between the two groups of subjects. An improvement in the occlusal conditions could not, after consumption of drinking water with an optimum fluoride content, be convincingly demonstrated by means of the epidemiological method used in these investigations.

Adolescent↗

Distant consequences of traumatic injuries to deciduous teeth--a case report.

The ever increasing number of injuries to deciduous teeth in children constitutes a serious problem in paedodontics. Among many factors that facilitate tooth injuries are malocclusions, and most specifically protrusions of upper incisors of Class II/1 according to Angle. This is a case report of a 6-year-old girl with irregularities of upper permanent incisors due to traumatic injuries to deciduous teeth. In view of the ongoing child development processes, medical check-ups following injuries to deciduous teeth should be undertaken once every two or three months. Since such injuries have an impact on the development of the masticatory organ, children should undergo medical inspection and observation immediately upon the completion of relevant post-trauma treatment.

Child↗

[Dentomaxillary and -facial problems in cleidocranial dysplasia].

A 14-year old boy with cleidocranial dysplasia was referred because of an almost complete presence of the deciduous dentition. Diagnostics by means of a panoramic radiograph, lateral headfilm, CT scan and 3D computer images of the dentomaxillary complex showed 7 supernumerary permanent teeth: 13', 11', 21', 23', 28', 35' and 45'. A combined orthodontic-surgical treatment was started. The supernumary teeth were removed surgically and the impacted teeth are exposed. The closed eruption technique was used to extrude these teeth orthodontically.

Adolescent↗

A novel GJA 1 mutation in oculo-dento-digital dysplasia with curly hair and hyperkeratosis.

Oculo-dento-digital dysplasia (ODDD) is a rare autosomal dominant congenital disorder mainly affecting the development of the face, eyes, skeletal system, heart and dentition. ODDD has been mapped to chromosome 6q22-q24 and germline mutations have been identified in the connexin 43 gene, GJA1. Abnormalities of the skin, hair, and nails have been recognized in ODDD but are often easily overlooked. We report an ODDD patient with curly hair, early trichorrhexis nodosa and discrete keratoderma. Molecular genetic studies revealed a novel GJA1 mutation affecting the amino terminus of the gap junction protein alpha-1 (Cx43). In the light of the cutaneous findings in our patient and based on recent ectodermal dysplasia classification systems, we propose to include ODDD in the group of ectodermal dysplasias.

Abnormalities, Multiple↗

['Emily goes to the dentist'. Oral care for individuals with Down syndrome].

This article is primarily based on an editorial letter in the Journal of Oral Health and Disability that describes the visits of a patient with Down syndrome named Emily. Oral health care for individuals with Down's syndrome and other people with learning disabilities in The Netherlands is discussed. Due to the syndrome related oral aspects and specificity, the authors argue strongly in favour of working multidisciplinary within oral health care centres. The dependency of persons with Down's syndrome necessitates an appeal to parents, relatives and carers to maintain oral health. Client-centred care is mandatory for an optimal oral health condition of this vulnerable group.

Child↗

Talon cusp: report of a case.

Talon cusp is a developmental dental anomaly, normally located on the palatal surface of the anterior teeth, that can occur in both primary and permanent dentition. The aim of this article is to relate a clinical case of talon cusp that interfered with both the occlusion and appearance of the patient. During anamnesis, the patient told of difficulty masticating. Clinical examination revealed labial inclination of the maxillary central incisors, featuring an overjet of about 5 mm, with interposition of the lower lip and an Angle Class I occlusal relationship. A treatment plan was devised in which gradual grinding of both talon cusps, the fitting of a removable orthodontic device, and clinical and radiographic follow-up were carried out.

Child↗

Aberrant talon cusps: report of two cases.

Talon cusp is an uncommon anomaly seen both in primary and permanent dentition. In most instances they are associated with other clinical problems such as occlusal interferences, poor esthetics and caries susceptibility. Management of such instances requires a comprehensive knowledge of the clinical entity as well as the problems associated with it. Here, we present two cases of talon cusps.

Child↗

Occlusal/dental anomalies found in a random sample of Nigerian schoolchildren.

OBJECTIVE: The aim of this study was to assess the occlusal/dental anomalies needing early treatment for maximal occlusal development among 11-12-year-olds in Ibadan, Nigeria. MATERIALS AND METHODS: An epidemiological survey of 361 school students, 171 (47.4%) males and 190 (52.6%) females, was carried out in Ibadan, Nigeria. Subjects were randomly selected from different schools in the city. One examiner, under natural illumination in the school premises, examined all the children. RESULTS: Prolonged retention of primary teeth with displacement of the permanent series was observed in 4.2% while dental anterior cross bite accounted for 5.5%. Oral habits with their deleterious effects on the occlusion were noted in 5.0%. Other findings were: clinically missing permanent teeth, 3.6%; supernumerary teeth, 1.4%; double teeth, 1.9%; carious lesions, 6.9%; conically shaped lateral incisors, 1.4%; and transposition, 0.6%. Proclination of the upper incisors with increased overjets of more than 5mm, as well as some fractures of the incisors, accounted for 22.4%. In all, 51.8% had one form of occlusal/dental need or another. No statistically significant gender differences were observed for all the various needs (p > 0.05) except the prevalence of supernumerary teeth, which was statistically higher in males (p < 0.05). CONCLUSION: Over half of the children could benefit from one interceptive need or the other for proper occlusal development. Routine dental check ups are very much encouraged in developing countries like Nigeria, as in other developed parts of the world.

Anodontia↗

Alternative oral rehabilitation of children with hypodontia and conical tooth shape: a clinical report.

This case report outlines an alternative oral rehabilitation treatment of a 4-year-old boy with hypodontia and conical tooth shape, which along with other characteristics led to a suspicious ectodermal dysplasia diagnosis. Diagnostic waxup and a silicone matrix formed the basis to the successful reconstruction of the anterior teeth with resin composite. Additionally, removable partial dentures were fabricated to improve esthetics and chewing ability. Positive psychologic influence of this alternative treatment on this patient is also discussed.

Anodontia↗

The prevalence and pattern of hypodontia of the permanent teeth and crown size and shape deformity affecting upper lateral incisors in a sample of Jordanian dental patients.

OBJECTIVE: The aim of this study was to determine the prevalence and pattern of hypodontia and the extent of congenital malformation in the permanent teeth of a sample of Jordanian adults. MATERIAL AND METHODS: Clinical examinations were carried out on 1045 dental patients aged 16 to 45 years to record any congenital absence of teeth except 3rd molars and to note any crown shape or size deformities affecting the upper lateral incisor. The congenital absence of permanent teeth was confirmed by taking complete dental history and orthopantomograms. Impacted teeth and teeth lost as a consequence of extraction or trauma were recorded as present. RESULTS: The prevalence of hypodontia was found to be 5.5% of the sample and the lower second premolar was the most frequently missing tooth. The number of missing upper lateral incisors was significantly higher than that of lower lateral incisors, (p < 0.05). Peg-shaped and reduced size upper lateral incisors were observed in 2.3% and 2.9% of the sample respectively. There were no significant differences according to gender, location of tooth according to arch or side of the jaw and hypodontic pattern. CONCLUSION: The prevalence of hypodontia was 5.5%, that of peg-shaped lateral incisor was 2.3% and that of reduced crown size was 2.9%.

Adolescent↗

[Oesteogenesis imperfecta--genetics, diagnosis and medical treatment].

The molecular background for osteogenesis imperfecta (OI) is mutations in one of the two genes (COL1A1 and COL1A2) encoding collagen I. The disease is characterised by varying degrees of fragile bones, retarded growth, bone deformities, tooth abnormalities, blue sclerae, and hearing loss. Treatment with bisphosphonates reduces the incidence of fractures in children with severe OI, while this still remains to be demonstrated in adults. Results from bone marrow transplantation and animal experiments may lead to alternative treatment in severe OI.

Adult↗

Teratogenic effects of nicotine on first molar odontogenesis in the mouse.

Fetuses of pregnant CD-1 Swiss albino mice, exposed to 0.1% nicotine sulphate at a dose of 1.67 mg/kg body weight from the 6th to the 15th gestational day, were compared with control fetuses to assess the effects of nicotine on first molar odontogenesis. Mothers were sacrificed on the 18th day of gestation. The 130 nicotine treated fetuses, as well as the 348 control fetuses were embedded in paraffin and sectioned in the frontal plane. The developing molars of the experimental fetuses were retarded, less differentiated, and reduced in breadth in comparison with controls. The developing molars of the control fetuses were in the bell stage of odontogenesis, whereas those of the experimental population were either in the late cap or early cap stage, depending on the absence or presence of palatal cleft, which occurred in 9.6% of the fetuses. It is suggested that nicotine, or its metabolic byproducts, interfere with normal interaction between the epithelial and mesenchymal components of the developing tooth.

Animals↗