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[Severe Basedow's exophthalmia. Indications for surgical treatment apropos of a case].

This report is concerning a case of bilateral Grave's exophthalmia which underlines that it may appear without hyperthyroidism, and progress in an independent way. The association of diploidy, decrease of the right side view (5/10: P.3) and many episodes of keratitis invited us to use surgery. The surgical technic used, rather similar than Tessier's, consisted of an opening of the external orbital wall with section of the anterior part of the temporal muscle by a half coronal approach, lowering of the orbital floor, and breaking in of the planum bone by an inferior eyelid approach. One year later, the result was rather successful, the esthetics improved, the right exophthalmia decrease (from 27 mm to 23 mm) and the right side view became again normal 10/10e P. 2. Others surgical technics have been used, but we choose and appreciate Tessier's because it was clearly indicated, and concerned the three orbital walls.

Adult↗

[Primary intracranial epidermoid carcinoma accompanied with epidermoid cyst in the cerebellopontine angle--a case report].

A case of epidermoid carcinoma arising in an epidermoid cyst in the cerebellopontine angle is presented. Clinical features and CT appearance are discussed in comparison with those of benign epidermoid cyst. A 43-year-old man was admitted to the Department of Neurosurgery, University of Tokyo Hospital on April 14, 1983, with complaints of right facial numbness and weakness of six months' history. On neurological examination, sensation of the right half of the face was decreased in all modalities. Marked atrophy of the ipsilateral temporal muscle was also noted. Right facial paresis of peripheral type was evident. Gag reflex was decreased on the same side. Except for a slightly increased left deep tendon reflexes, there were no pyramidal tract signs. A CT without contrast material failed to show any abnormalities. A postcontrast CT demonstrated an irregular enhancement in the right cerebellopontine angle. The finding of asymmetry of the ambient cistern indicated minimum mass effect on the metrizamide CT cisternography. Suboccipital exploration of the right cerebellopontine angle was carried out on April 28, 1983. Leaving a part of the capsule indenting the pons between the roots of the fifth and the seventh nerve, we removed a white pearly tumor. Histological diagnosis was typical epidermoid cyst. He left the hospital one month later with signs of the right seventh and the eighth nerve. His postoperative course, however, was beyond our expectation. Over a few months following his discharge, left hemiparesis as well as horizontal and vertical nystagmus gradually developed. He was readmitted on November 10, 1983. A postcontrast CT revealed enlargement of the enhanced lesion filling the right ambient cistern.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Management of cryptococcosis and toxic epidermal necrolysis in a dog.

Generalized cryptococcosis with CNS involvement was diagnosed in a 3-year-old spayed German Shorthaired Pointer. Clinical findings included Horner's syndrome, generalized lymphadenopathy, temporal muscle atrophy, and chorioretinitis. Toxic epidermal necrolysis resulted after 19 days of treatment with 5-fluorocytosine and amphotericin B. After discontinuation of the 5-fluorocytosine and amphotericin B and treatment with cephradine and ketoconazole, the toxic epidermal necrolysis resolved. Treatment was completed without further complication by using amphotericin B and ketoconazole concurrently.

Amphotericin B↗

[Reduction of radical cavities by homologous cartilage chips].

The article reviews, first of all, the common obliteration methods of radical cavities. This is followed by a description of the author's own technique which has been practiced for the last 13 years. This method employs preserved (Cialit solution 1:5000) homologous septal cartilage chips, shaped into small cubes of 3-4 mm. size. The chips are implanted in obscure districts (apical mastoid, sinus dura angle) of radical cavities for primary or secondary (old cavities) partial obliteration, as shown in Figs. 1 and 2. Crushed homologous septal cartilage plates and temporal muscle fascia are placed additionally on the chips. The effect is the construction of a small, easy-care cavity, which can be appreciated at a glance. Statistical results of 314 cases (170 cases of primary obliteration, 144 old cavities) are presented. Chips in cavities are well tolerated. Chips were partially rejected in 13 cases only, whereas in 3 cases they were completely rejected. A permanent dry cavity and dry ear was achieved in 86% of the cases. Cholesteatoma recurred in 5 cases. The homologous cartilage technique is contraindicated in fistulas on the labyrinth or fenestra, as well as in exposed facial nerve or dehiscence of the facial nerve canal, in case of healed fistula of the dura, and in dissection of the sinus sigmoideus. In these cases, autologous cartilage (tragus, cavum conchae) must be implanted. One of the most important advantages of this method is that there is no crumpling up of the obliterated areas and no retractions over a longer period of time, compared with other relevant techniques (i.e., pedicled subcutis muscle grafts or free tissue flaps).

Cartilage↗

[Nontraumatic chronic subdural hematoma due to dural metastases of breast cancer. Case report].

A case of nontraumatic chronic subdural hematoma due to obstruction of dural vessels by tumor cells is presented and 25 reported cases are reviewed. A 39-year-old female was referred for headache, vomiting, disturbance of consciousness and right homonymous hemianopia with macular sparing. She had undergone mammectomy for medullary nodular carcinoma of the left breast five years before. She had been treated with combined hormonal therapy and chemotherapy for the cancer metastases to the liver in preceeding six months. Hematological examination revealed drug-induced thrombocytopenia, increase of FDP in blood (80 micrograms/ml), but no abnormality of prothrombin time and fibrinogen content. Therefore in the present case there was no evidence of disseminated intravascular coagulation (DIC) after Colman's criteria. However, it was suggested that this case had compensated DIC after Cooper's criteria. CT scan showed a biconvex-shaped low and partially iso-density area over the left fronto-temporal convexity, indicative of chronic subdural hematoma, and no abnormal findings in the occipital area. After removal of the hematoma she became alert without headache and vomiting. However, seven days later she complained of headache and vomiting again. Repeated CT scan showed a larger biconvex-shaped low density area over the left hemisphere extending to the parietal region at that time. Second operation was performed, but she expired four days later. Autopsy showed systemic metastases of the medullary nodular carcinoma in the scalp, temporal muscle and dura as well as lungs, adrenal glands, ovaries and bone marrow.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗