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At least 793 records · Page 44Linked to original sources
PubMed1987

Adrenoleukodystrophy in a mother and son.

A 6 year old boy died from a degenerative brain disease which was clinically and pathologically typical of adrenoleukodystrophy. Shortly before his disease became manifest his 28 year old mother had presented with similar symptoms, and subsequently died. Her brain showed almost identical features including the presence of pathognomonic ultrastructural inclusions. The accumulation of very long chain fatty acids in cerebral white matter as well as high hexacosanoic to docosanoic acid (C26:22) ratios, substantiated the diagnosis in both cases. This is one of the few documented cases of adrenoleukodystrophy in an adult female, and is almost certainly an example of clinical manifestation of this X-linked inherited disease in a carrier.

Adrenoleukodystrophy↗
PubMed1990

Fragile sons or harassed daughters? Sex differences in mortality among juvenile primates.

In most mammals, juvenile males tend to be more vulnerable to starvation than females and consequently experience a higher mortality. This has been attributed to selection on high male growth rates in response to strong intrasexual competition. Among primates, by contrast, it has been noted that females tend to be less viable as juveniles. This has been attributed to a greater ability of juvenile males to contest for food. An alternative explanation is that there is local resource competition, and adults of the resident sex (usually females) attempt to limit the recruitment of unrelated immatures of the same sex by harassing them. These ideas are not mutually exclusive. A set of predictions from these three hypotheses was derived for two social systems and two levels of food supply. They were tested using estimates of juvenile mortality and juvenile sex ratios of non-human primates based on over 40 data sets drawn from the literature. The results indicate that the local resource competition hypothesis provides the best explanation for the observed patterns in differential juvenile mortality in primates. The contrast between the findings for primates and those for other taxa is attributed to the low growth rate of immatures and the widespread occurrence of conditions conducive to local resource competition in primates.

Animals↗