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[Characteristics of the reactogenic and immunogenic properties of killed influence vaccine purified and concentrated by the method of adsorbed chromatography on silicate sorbents].

Reactogenic and immunogenic properties of killed influenza vaccine prepared of various strains of influenza virus by the method of sorption chromatography on sliciate sorbents were studied on small groups of volunteers; there proved to be a moderate reactogenic and a marked immunogenic activity of the experimental batches of the preparation. The dose, the concentration and the method of administration of the vaccine to obtain the immune response were determined. The indices of humoral and local immunity following a single vaccination were studied. On the basis of parenteral immunization of donors with killed influenza vaccine there were obtained experimental samples of the antinfluenza gamma-globulin with an increased specific activity.

Adolescent↗

[Personal experience with administration of Smektit (hydrated magnesium aluminum silicate) in the treatment of diarrhea of non-infectious origin and diarrhea after resection of the large intestine].

Smektit was used for treatment of 24 patients, incl. 10 hospitalized with diarrhoea of a non-infectious etiology (postoperative period, non-adherence to the dietetic regime). Microbiological examination involved only examination of the common flora of the large bowel. In the 10 hospitalized patients the complaints receded very rapidly, after a maximum of three days. In the remaining 14 patients who had resections on account of colorectal carcinoma the diarrhoea was in the majority due to reduction of the large bowel and thus reduction of the resorption area. The condition of ten patients became stabilized and the frequency of bowel movements decreased. In the group of four patients after subtotal colectomy only one patient improved. In three patients smektit administration had no effect. In these patients the cause of frequent bowel movements was the extensive reduction of the large bowel.

Adult↗