[Problem of the vinyl chloride hazard in relation to the hygienic aspects of using polyvinyl chloride materials].
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The results of an investigation on environmental dust concentration and individual dust exposure in a drying and sacking section of an "emulsion" and "suspension" PVC plant are reported; data on environmental concentration and individual dust exposure have been obtained by gravimetric techniques using similar personal and static dust samplers. Morphology and particle size distribution have been studied by electron microscopy on airborne dust specimens. Morphological analysis showed remarkable differences concerning shape and size between particles sampled in the "suspension" polymer and "emulsion" polymer sacking sections. Remarkably high mean values concerning dustness have been observed: 1.30 mg/m3 (min. 0.15; max. 18.4 mg/m3) for environmental concentration and 5.39 mg/m3 (min. 0.28; max. 45.6 mg/m3) for individual exposure.
In 255 workers of two PVC processing plants no changes have been found in routine laboratory tests. No deviations have been found in blood serum, bilirubin, cholesterol, creatinine, nitric residue of urea, calcium and phosphorus, either. Similarly, the activity of acid phosphatase and gammaglutamylotranspeptidase was not changed. In most examined groups a slight statistically significant increase in ALAT activity has been found, in others--increase in the activity of AspAT and basic phosphatase. Workers exposed to lead did not exhibit any laboratory plumbism symptoms. On the other hand, a significant decrease in the activity of erythrocytes deltaaminolevulinic acid dehydratase has been found. The studies suggest that workers processing PVC most probably exhibit slight toxic liver lesion.
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